Basic Information

Insect: Kallima inachus
Gene Symbol: MBD-R2
Assembly: None
Location: HiC:5421470-5440788[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.43 39 5.3 0.7 1 23 350 372 350 372 0.97

2 11 0.00029 0.027 15.3 7.0 1 23 379 401 379 402 0.95

3 11 0.05 4.6 8.3 1.8 1 23 406 428 406 428 0.97

4 11 0.045 4.1 8.4 1.8 1 23 433 456 433 456 0.97

5 11 0.014 1.3 10.0 0.2 1 23 460 483 460 483 0.93

6 11 0.012 1.1 10.2 0.5 3 21 497 515 496 520 0.93

7 11 0.9 82 4.3 0.3 2 23 572 594 571 594 0.94

8 11 0.0067 0.62 11.0 0.7 2 20 610 628 609 631 0.91

9 11 8.8e-05 0.0081 16.9 0.6 1 23 637 659 637 659 0.97

10 11 4.8e-06 0.00044 20.9 2.3 1 23 666 688 666 688 0.97

11 11 3.8e-05 0.0034 18.1 4.1 1 23 694 717 694 717 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.43	39	5.3	0.7	1	23	350	372	350	372	0.97
2	11	0.00029	0.027	15.3	7.0	1	23	379	401	379	402	0.95
3	11	0.05	4.6	8.3	1.8	1	23	406	428	406	428	0.97
4	11	0.045	4.1	8.4	1.8	1	23	433	456	433	456	0.97
5	11	0.014	1.3	10.0	0.2	1	23	460	483	460	483	0.93
6	11	0.012	1.1	10.2	0.5	3	21	497	515	496	520	0.93
7	11	0.9	82	4.3	0.3	2	23	572	594	571	594	0.94
8	11	0.0067	0.62	11.0	0.7	2	20	610	628	609	631	0.91
9	11	8.8e-05	0.0081	16.9	0.6	1	23	637	659	637	659	0.97
10	11	4.8e-06	0.00044	20.9	2.3	1	23	666	688	666	688	0.97
11	11	3.8e-05	0.0034	18.1	4.1	1	23	694	717	694	717	0.95

Sequence Information

Coding Sequence: ATGCGGTGCTGTGTGCCTTCATGTAAAAACGATTCGAGGCATATTTCAAAATCGCAAGGGATAACATTTCATGTTTTTCCAATGGAACCGAACCTTCGTGCATCATGGTTAAAAGCTGTTGGGAAAGACACATGGTCACCTAGAGAACGAAGTGCAGTTTGCTCAGAACATTTTTCATGTGATGATCTTTATGAAACTAAGAGTGGTTTGCGGAAAGTTAGATCCGGAGCTGTTCCCACTGTATTACAGGACGCTTCAAACTGTGATTTTGGTGAATCTGTAAGTTCGAAGGTATGCAGAATATGTCTTGCAATGGATTTAAAATTGTATCCAATGAGAATATTTAAATTAGAAAAGGCTTATGAGAATTTGACTGGACTAACGCTATCTCATGAAGATGATCTCCCGCAGAAGTTGTGTGCAGAATGCGCTAGAAGATTGTTGAATTGTGATAAATTGAGAAGCAAAAGTTTAAGAGCGAACTTGTTGCTGCTAGAATTGATTAAGAAGCAGAAGCTTTTAACAATACAAAATATAAATACAATAAATCGTGACAACAACCAACTGACCTCGAACTTAACTAATAAAACATTCGAAACCGACCACTGTGATGTATACATAGAATACAATGAAAACCAAAAGGAACAGACCGACAAAAATCCAATCCAAGAAATAACATTAGACGTTAAGAGTGAGAAGAATGAAGAAATATACATTAACGAGATTTACACTGAAGCAAAAGACGAAATTAATATCAATCATACAAACGATGAAAACGATACTGATTTTATAGTGAATAATTATTCCTCAGACGATAGCTTGCCTCTAGAAACACAAAGAAAGAAAGTTAAAAAGATAAAGACAAAAGAAAAGAAAAAGAAAAAGATAGTTAAGAATCAAAATGAACCAAAGATAGATAGACGGAGAAAGCCATTCCTAAATGATGATTTAAATGAAACGTTATTCACTATAACAGATCTAACATTTGATGAGCAAGTCGCTGAAATTCTCAAAAGGCAAGAATCGTCGAATTATAAGAATTCAATGTATAAGTGTACGGCTTGTTTTAAAGGGTTTTTGGATGAAACGGCATATAATGGTCATATGACGCGGCATACTAACCAATGCGGTGAATACGAGTGCGACATATGTAAAACGCATTTTAAACACCCGCACGCGTTAAGAAAACATATAACCGCACACCACACACAGAGGTTCAGTTGTAATCAGTGTCCGTATGTCACAACTCACCGACAGACAGCGAGACTACACGAGAGATGGCACAAGGGTACGAAATATCAGTGTCCACATTGCCAAGACGAATTCGTTAAATTTACAACATATATGGGTCATATTCGTATAAAGCACCCATCGGATTTCGTTTGCGCGCTCTGCGGGTATTCCTTTGTCAGTGAGAAAGGGATAGAGCTACATAAGAAATTAAAACATCGTCTTGATGACGGACAGATACCGGATGATGGACCGCTCTGTGACTTGTGTAATGTTAGATTCGTATCACAAGAAGCGTATAGAAGGCATTTACACGTATCCGGGAGGCATAACAACAGTGACTCAGACTCAAAAGAATCAAACAAAACGAGAAAGGGAAGAACGCGTGTAGTCAGAGAGAAGAAGAGGAGCATAGATAATATAGAAGATGATGAAAAGAAAAAAGTATATCCCAGTCAGATGAGGAAGGCTGAAGGACCAATACCTTGTGAGCAGTGTGGGATTCAATTAGAAGATTCGAGAGCGTACCATGGACACTTCAGACGGATGCATCCGGATAAGAATCGAACCAACTACCCATCCATGAAATCGCCTTGTATGTGCGAAGTCTGCGGGAGAATGTTCCAAAGTTACGCTCTATTAAAAGATCATCGATGGGTGCACACTGGCGAACGGCCGTTCGCGTGCGAATCGTGCGGGAAGTCGTTCCGGATGCGGCAGCGTCTTGTCGCACATCGGAGGGTCCACGCTCCGCGAAGAGCCGCTTACGCCTGTGCGCTTTGTGGGAAGAGCTTCAGCACGCACAGCAACCGACAGCGACATATGTTCATACACACGGGTTTGAAGCCGTTCAAATGCGAGATGTGCGGTAAATGCTTCAAGCACGCGAGCGAGAAACGAGCTCATATCACCTACGTCCATTTAAAGAAGCCCTGGCCGAAGAGGGCTCGAGGAAAACGACGGACGGACAGACCTGGACAGCTGATGGGTCAAGGTTCGATACCAACGGGTGCAAGCGAGATGGATATAGCTCAGCCGATGTGGCCCAATTGTGACCCTAAAATGGGGGACATGAACAATATTATAGACGATAAACCCATTTATTATAACTTAAAAATATAG
Protein Sequence: MRCCVPSCKNDSRHISKSQGITFHVFPMEPNLRASWLKAVGKDTWSPRERSAVCSEHFSCDDLYETKSGLRKVRSGAVPTVLQDASNCDFGESVSSKVCRICLAMDLKLYPMRIFKLEKAYENLTGLTLSHEDDLPQKLCAECARRLLNCDKLRSKSLRANLLLLELIKKQKLLTIQNINTINRDNNQLTSNLTNKTFETDHCDVYIEYNENQKEQTDKNPIQEITLDVKSEKNEEIYINEIYTEAKDEININHTNDENDTDFIVNNYSSDDSLPLETQRKKVKKIKTKEKKKKKIVKNQNEPKIDRRRKPFLNDDLNETLFTITDLTFDEQVAEILKRQESSNYKNSMYKCTACFKGFLDETAYNGHMTRHTNQCGEYECDICKTHFKHPHALRKHITAHHTQRFSCNQCPYVTTHRQTARLHERWHKGTKYQCPHCQDEFVKFTTYMGHIRIKHPSDFVCALCGYSFVSEKGIELHKKLKHRLDDGQIPDDGPLCDLCNVRFVSQEAYRRHLHVSGRHNNSDSDSKESNKTRKGRTRVVREKKRSIDNIEDDEKKKVYPSQMRKAEGPIPCEQCGIQLEDSRAYHGHFRRMHPDKNRTNYPSMKSPCMCEVCGRMFQSYALLKDHRWVHTGERPFACESCGKSFRMRQRLVAHRRVHAPRRAAYACALCGKSFSTHSNRQRHMFIHTGLKPFKCEMCGKCFKHASEKRAHITYVHLKKPWPKRARGKRRTDRPGQLMGQGSIPTGASEMDIAQPMWPNCDPKMGDMNNIIDDKPIYYNLKI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00825075;
90% Identity: iTF_00825075;
80% Identity: iTF_00843595;