Basic Information

Gene Symbol
zfy1
Assembly
GCA_028829205.1
Location
JAPOND010000028.1:53210-58598[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 4 3.4e+02 2.7 0.3 2 23 6 27 5 27 0.94
2 13 4.1 3.6e+02 2.6 0.2 1 23 1012 1034 1012 1034 0.92
3 13 9.1e-05 0.0078 17.3 1.6 2 23 1037 1058 1036 1058 0.96
4 13 0.0067 0.58 11.4 3.3 1 23 1064 1086 1064 1086 0.98
5 13 0.015 1.2 10.4 2.8 2 23 1093 1114 1092 1115 0.95
6 13 0.23 20 6.6 1.5 6 23 1129 1146 1127 1146 0.97
7 13 0.018 1.5 10.1 1.1 3 23 1153 1174 1152 1174 0.96
8 13 0.019 1.7 10.0 0.1 2 23 1187 1207 1186 1207 0.96
9 13 0.0063 0.54 11.5 1.9 1 20 1213 1232 1213 1235 0.87
10 13 0.0075 0.65 11.3 1.4 1 23 1243 1265 1243 1265 0.98
11 13 0.0052 0.44 11.8 7.2 1 23 1271 1293 1271 1293 0.98
12 13 6e-06 0.00052 21.0 1.3 1 23 1299 1323 1299 1323 0.98
13 13 0.00094 0.081 14.1 5.1 1 23 1329 1351 1329 1352 0.95

Sequence Information

Coding Sequence
ATGGATCAGAGAGTGCAATGCCCTGTTTGTACACTGTACCTACACAGTGGAATGTCCTTAGAGTCACATCTGGACACTCATCCAAAAGATCAAAGGTCTTATAGGAGTAGGTCAAGAACACCTGCTACTGATGATAGTGGTAGATGGGCTACATCACATCGCAATAATGAAAATGAAAGGTTTTGGAGGAGAACTCCAAGTCGTACAAAGTCTACTCCAACTTCCAATACTTCAAGAAATCCTACACCAGACCTCAGAATTAGCAGTATAACTTTTGAAAACACCTCAAATAATAATTCAAGTCAATGTTCAGACTCTTATACTGTGAAATCAGATAAAACACAGCAGACATTTGGTTCCAATGCTCCATCATCAGACTTTGATCAACCATATCCTTTCTTTCCGGAGCAACAAGAAGATgcagaaataaaattttcacgTAGCACTGAATACAGTACACAAATTGAAAATCCAAGTAACATGTTTGGGTACAACACACCAATCTTGGGATCAAGTGATAAAATGCCTCCCACTGCACCAACAACCTCTAGAAAGGGTAATGACTATGTTAAAATAGTGCCAAAACCAGGAAATATTCTGTTAAAAAGCAATGTTGGAGGAATGCAGTATCTGGCACCGGGTGTGAAACCTTTGCATGTTATGATGCCAACTACTCCACCATTTGTTCAGAAGAATTTGCAGAACAACATGATTATGTCCGGAACGTTACAAGGTTCCCCAGTAATGGATCCAAAAACAATATCAACTTCACATTCTAACCAATTTAACCAAATTACACCAGGAACCTTTACACCAGGCACCACAGTTGTCACTCAGAattcacaaattatttatagagaGATGGTTCATAACTTGGATGGGAAACCGTTTATTTCCAGTGGACCTCTTGCGCTTGGTACTCAAGATAATGTCACAAATGTACCACAATCTAGTTCTGTGTACCAAAATGTAATGGTTGTGGATCAGTTTGGTAATACTTCATGTATGTACACTCCTCCACATCTATTATCTAAatcaaataattcttttaatgaAAATGTACCATATATGCAAAATGTGCCAGAAAAGTCTGTTCCTAATGTAGTTAGTGATGCAAACAAAACTCTAATTATTGAAGTAAGTCCTATGTTACCGCCTGGTACCACTAGTAGTAAAAGTTCTTGTGCTAGTGAATTGCTGCCAGCTCCACaatctgttaataaaaaaatggaactTGAAAAATCAGATTCAAAAAATGATAATTCAGGACCCACTAAAGGTCTTAAAATTCTAAGCAATATTAAGGTAGAAGTTCCTGTGCAGCATCACAAAAATATGCTTAATACTGTAATGGATCTGACTGGTTCAACTGATGCAGAATATCCTGATCCATCAGTTACACCAGAAACAATCTTACCAGATTTAGATGACAATAGTCCAGGTATAACTAATGGTTGTATTCAACCCTTGACTAGTGGTGTTGATAGCTTAGGTTCAAACTCattttctgttataaaaaattCTAGTAACTCCTCATTCAAAGAGAGTGTGGGCAAGCAAAGTACTGTGGATAATAAACTAGATGCTGAGTTTTCTGATAGTTGTCCTGTTCCTGATCTAACTTGCAATGAGAAACCATCCATATCACCATGTAGTGAGTTATCAGAACATGGAGATAATTCTATTGACTGTACATCTCCTTTTCCTAAGCCGGAAAGCAGCCGGTCACAAAGCACTGTGAATAGAATGGACAAAggaaaaaaaactgttacaaaACCAAGAAACAATCTTCTCAggcttaataatatatttgtaaaaaaacataaaaaagttctacaaataaaaaacgCCAAATTCTATCCACCTCACCTTACTAGTCAGGCACAGGAACAAAGGGAATCTTCTTCATCAAACAAATCACCAGAAAACTTTAGTATGAATAAAATTCATTCTGAGAATGGCGATTCCAAGTCTAGTGGAAGCATTCATACTATTACTAttgaaaaaattaaagttattgagGACCATCAAAACGAATTTGATGCTAACACAGAAGAACAATCAATGGATATTGAACCAGTAACACCTTCTAATGTTAACCAATATACAACCACTGTTGATATGGTCCATGTCAAAGAAGAAGTAAATTCAAGTAATGATTTTAGCAGTGAGGATAGATCATCTACAGATATTGCACCCATGGAGACCCTAAGacctataaatgtaataaattacagtAACATGGGTGGAGATTTTGATGACGAATCGAATCACAGAGAGCTACTGGAATTGGAAGCGGCGTCTAAGAACAAGCAATTTGTGTCAATGATGAATGAAAACTATTTCGGGGACAATATCTATGCGGACTACTTTACTCCAGATCGCGTGGAAGCATTTGAAGCTGCAAAAGAAAATAGTTATGTCAAAGAAAATTCAAAAGATTCCATGTATATTTGGGGTGAACCTTCGCAGAAGGAAAGCGAATTCGTTCTGCCTAATTTCATTCACGAGAGTTACAAAATTGCCGAAAACGGGGTTGATTATTCTGATGTAGCTGGTGATAACCAGACAGATGCGGAAGTTGACAGATGCGAAAGAGACAGCAAAGTGGATGTGTTAAGCGAACGCAGTGAAGGTGAAACTCCCTTGAACATCTGTTCGGACGAAAGAATGCCGCCTCGTGGGGAGCTGAGCGGCCAAGAGAGCAACGGGGATATGGAGTCGCCGTGGACTGGGATGTACTCCGGAGTGCCACCGGCGGAACCCTACGATCTCATGGCTCGAGAGAGCTGGGTCTCCGACGCCTCTGATGACGATGCCAACGAAAAGACTGAAAATATCCGCCTGCTAACTGCCCGCGCCATCAAGAAAGAGGAGAAACCTGACGAATCCGTTTTGGCAGGCAATCTCCTGACATTAGACTCTAAGGAGTCGATGACGACGACGATGCTACAAGTGTACGACGCGATGAATGAAACGAAGCCGCAAATAGAGGGACTCATTAAATCCGAGAATAGAAAGAGAAGGCGAGATTACGTCTGTCCCACTTGTAAAGTGGATCAAATTACTGAGGCGGGGTTCCACGCTCATCTTAAGATACATCCGCTGGAGTGTCTCACGTGCGGAAAGTGTTTCTTCCGACGAGCCAATCTGGCGCTACATGCGAAAACACATACGGGAATTAAGAATTTTAAGTGCGAAATCTGCGAGAAGCGCTTTTTGACGCGTCAAAAGCTGACGGAGCACCATAACGTACACACGGGGCGAGCGCCCGTTAAGTGCACCCTCTGCGATGACACCTTTCGACGCTACTCCAACATGGTGCAGCACAGGGACCGCCACCACTTCAAGAAGAAGGCGAAGGTGCGAGACTTCGTGTGCTCGTGTGGCGCAGTGTTCCACTCGCGCGCCAAGCTGCGCTGGCATCGCGAGACGCACGACGAGCGACCCAAGGCCTGCCTCTACTGCAGTGACAAGTTCGTGCACGCCGCCTCGCTCACGCGCCACGTGCGGCGCTCCCACAACGACCACTACACACGCGGACAGCGACACAATGTGCCCTGTCCCGTCTGCAAGCAGATGTATCTCCGGACGAACTTGCGTGCACATCTTCTGACTCACAGCGGGAAACGCCCCTACCACTGCATAGTATGCAACAAGGCATTCACCACCAAGTGGAACCTGAAACTGCACAGATGGACGCACCTCGGGCGTTCGGCGAAACCTTATAAGTGTACTCTATGTAAGGGCGCCTTCATCAGACACACGGAGTACGTGTCTCACATGAACGCTCATAAATCCGTTCGACCCTACACCTGTAACTACTGTGGCTGCCAgttcataagaaaatataattgtcaGAGACACGTACGCGAACACGAAATGGCCAAGAAGTACGTGTGTAAAGTGCCCGAGTGTGGTAAATCGTTCCACAGAAGCTACTATCTGTCGGAACATATGAAGGTTCACAGTGGAGCTCGTCCGTTCTCGTGTAACATATGCGGGAAGACGTCGAGCAACAAGTCCAACCACAACAAGCACGTAAAGATCCATCACGCGAGGGAGCCCGTCGCCACGGAGGCCTAG
Protein Sequence
MDQRVQCPVCTLYLHSGMSLESHLDTHPKDQRSYRSRSRTPATDDSGRWATSHRNNENERFWRRTPSRTKSTPTSNTSRNPTPDLRISSITFENTSNNNSSQCSDSYTVKSDKTQQTFGSNAPSSDFDQPYPFFPEQQEDAEIKFSRSTEYSTQIENPSNMFGYNTPILGSSDKMPPTAPTTSRKGNDYVKIVPKPGNILLKSNVGGMQYLAPGVKPLHVMMPTTPPFVQKNLQNNMIMSGTLQGSPVMDPKTISTSHSNQFNQITPGTFTPGTTVVTQNSQIIYREMVHNLDGKPFISSGPLALGTQDNVTNVPQSSSVYQNVMVVDQFGNTSCMYTPPHLLSKSNNSFNENVPYMQNVPEKSVPNVVSDANKTLIIEVSPMLPPGTTSSKSSCASELLPAPQSVNKKMELEKSDSKNDNSGPTKGLKILSNIKVEVPVQHHKNMLNTVMDLTGSTDAEYPDPSVTPETILPDLDDNSPGITNGCIQPLTSGVDSLGSNSFSVIKNSSNSSFKESVGKQSTVDNKLDAEFSDSCPVPDLTCNEKPSISPCSELSEHGDNSIDCTSPFPKPESSRSQSTVNRMDKGKKTVTKPRNNLLRLNNIFVKKHKKVLQIKNAKFYPPHLTSQAQEQRESSSSNKSPENFSMNKIHSENGDSKSSGSIHTITIEKIKVIEDHQNEFDANTEEQSMDIEPVTPSNVNQYTTTVDMVHVKEEVNSSNDFSSEDRSSTDIAPMETLRPINVINYSNMGGDFDDESNHRELLELEAASKNKQFVSMMNENYFGDNIYADYFTPDRVEAFEAAKENSYVKENSKDSMYIWGEPSQKESEFVLPNFIHESYKIAENGVDYSDVAGDNQTDAEVDRCERDSKVDVLSERSEGETPLNICSDERMPPRGELSGQESNGDMESPWTGMYSGVPPAEPYDLMARESWVSDASDDDANEKTENIRLLTARAIKKEEKPDESVLAGNLLTLDSKESMTTTMLQVYDAMNETKPQIEGLIKSENRKRRRDYVCPTCKVDQITEAGFHAHLKIHPLECLTCGKCFFRRANLALHAKTHTGIKNFKCEICEKRFLTRQKLTEHHNVHTGRAPVKCTLCDDTFRRYSNMVQHRDRHHFKKKAKVRDFVCSCGAVFHSRAKLRWHRETHDERPKACLYCSDKFVHAASLTRHVRRSHNDHYTRGQRHNVPCPVCKQMYLRTNLRAHLLTHSGKRPYHCIVCNKAFTTKWNLKLHRWTHLGRSAKPYKCTLCKGAFIRHTEYVSHMNAHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKYVCKVPECGKSFHRSYYLSEHMKVHSGARPFSCNICGKTSSNKSNHNKHVKIHHAREPVATEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01034965;
90% Identity
iTF_01034965;
80% Identity
-