Isal017235.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ithomia salapia
Gene Symbol
PLAGL2
Assembly
GCA_028829205.1
Location
JAPOND010000230.1:1892510-1894039[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 5.8e-05 0.005 17.9 1.4 1 23 113 135 113 135 0.97
2 7 6.7e-05 0.0057 17.7 1.7 1 23 141 163 141 163 0.96
3 7 1.4e-08 1.2e-06 29.3 2.0 1 23 169 191 169 191 0.97
4 7 0.12 11 7.4 0.4 1 23 198 222 198 222 0.95
5 7 0.0018 0.15 13.2 0.2 2 23 230 251 229 251 0.97
6 7 0.00031 0.027 15.6 2.2 1 23 265 287 265 287 0.97
7 7 1.4e-05 0.0012 19.9 1.1 1 23 293 316 293 316 0.94

Sequence Information

Coding Sequence
ATGGCCAGTCCGCCACCGAACCCTAAAGAAGGTGCGGAGAGCGGCCCCGAGTTCCAGGAGGAGACGGGCGGCCAACGTGCGGCCGCCCCGCAGAAGAAGTTCATAGCGACGCCCGTCTCGCAGCTGCCGTCCAAGTTGGAGTACGTCGCTCGCGGGTCAACAGGTCGCAGCGTCAAGCATACCTTTCGCACTGTCAAGTTCGCCCGCAGAGTGCCCACGCTGCCGCCCAAGAAGCCCGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACTGGCCGGTGGCAGTGGCGCCGCGCCTGAGCGCCGCCCGCGCCGCGACCGCAGCAAGCGTCACGTCTGCACCACTTGCGAGAAGCGTTTCTCCAGCCCCGGCAAGCTCAGCCAACACGTTCTCTCTCATACTGGTGAGCTCCCGTTTTCGTGTGATTTATGTGACAAGCgttttaattctaaattcaaaCTTGTGCGTCACAGTCTTATACACAGTGAGTCAAGAGCCTTTGCGTGTACTGTCTGCGGTAAGACTTTTAATCGTAAAGATCATCTTACAAATCATATTAGGGTTCACAATCCTGTTAAGAATCTTTATACATGTGAGCTGCCCAATTGTAGGAAAACTTACACAGCTTTGTTGAGTTATCGTAGGCATGTTGCTTTACATTCTGCAGAGGAAGGCAATTTACAGTGTAAAATCTGCGATGAACTGTTTAATTCTAGGCAAGAAATTGTTAATCACCTTAAGGTTCATACAGGGAGTCGCACACCTAAAAGTGAGACTGATAAGAAGTTTACCTGTGATCATTGTGAGAGAAGGTTTTTTACAGCAAAAGATGTTAGACGGCATCTGGTTGTACACACAGGTAGGAGAGATTTCTTATGTCCTTACTGCCCTCAAAAGTTTGGCCGAAAAGATCATTTAGTCCGTCATGTTAAAAATGCACATCCTGAGGAGTCATGGAAATCTGCAGCAGTGGGCACTTCTACAGACCCACCTCCGGAAGCAACTTCATTTGAGGAAACTTATACACAGTACAATTTAGATGATACAGATTTTGATATCTGGAAAGCCATCACTCCTAAAGAGGAGATACAAGAGGGACGGACAGAAGTACCAGCCTCGGATATAATTGTAGAAATACCTTCAGATCTAGATATTAAAGTTGAACcattagatataaaattagaaaatccACCATCACCCAGTGAAATCCTCGAATATCCAGTAGTGTATATGGTACAACCGCCATATACACAAACGTCCTCCGACTTGCCATATATAGCCCAGCCGATTCGTGACCCTATTGATGTGCATTTATTAAGTTCGGGAAATGTCCAATCAATATTGATGGATCCAGGTGAAGGTCCATCGGGATTATCGACTCAAATGTTAGGGCTGCTCGAGGAAGGCGAACCAGCCTTTCCTAGTGAAGAAGGGCGCTTGCAGCAGCGGTTGCCGGCTTTCACGCAGGCCTTCCAGACCGCCCAGAGCCCCAAGCCACCGCCGCCTCCGCCCCCGCCCCACTAG
Protein Sequence
MASPPPNPKEGAESGPEFQEETGGQRAAAPQKKFIATPVSQLPSKLEYVARGSTGRSVKHTFRTVKFARRVPTLPPKKPXXXXXXXXXXXXXLAGGSGAAPERRPRRDRSKRHVCTTCEKRFSSPGKLSQHVLSHTGELPFSCDLCDKRFNSKFKLVRHSLIHSESRAFACTVCGKTFNRKDHLTNHIRVHNPVKNLYTCELPNCRKTYTALLSYRRHVALHSAEEGNLQCKICDELFNSRQEIVNHLKVHTGSRTPKSETDKKFTCDHCERRFFTAKDVRRHLVVHTGRRDFLCPYCPQKFGRKDHLVRHVKNAHPEESWKSAAVGTSTDPPPEATSFEETYTQYNLDDTDFDIWKAITPKEEIQEGRTEVPASDIIVEIPSDLDIKVEPLDIKLENPPSPSEILEYPVVYMVQPPYTQTSSDLPYIAQPIRDPIDVHLLSSGNVQSILMDPGEGPSGLSTQMLGLLEEGEPAFPSEEGRLQQRLPAFTQAFQTAQSPKPPPPPPPPH