Basic Information

Gene Symbol
-
Assembly
GCA_037464855.1
Location
JAZBHA010000617.1:42752-46072[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 3.6e-05 0.0016 18.5 0.7 1 23 176 198 176 198 0.95
2 15 0.0016 0.07 13.3 1.2 3 23 206 226 205 226 0.99
3 15 0.00014 0.006 16.7 0.1 1 23 334 356 334 356 0.98
4 15 0.04 1.7 8.9 0.1 1 23 362 385 362 385 0.94
5 15 4.4e-07 1.9e-05 24.5 3.0 1 23 417 439 417 439 0.98
6 15 0.0076 0.33 11.2 0.0 1 23 452 474 452 474 0.94
7 15 0.084 3.7 7.9 0.4 1 23 480 503 480 503 0.95
8 15 0.076 3.3 8.0 1.9 2 19 511 528 511 529 0.96
9 15 0.0003 0.013 15.6 3.6 1 23 538 560 538 560 0.97
10 15 0.0045 0.19 11.9 0.3 2 23 566 587 565 587 0.96
11 15 1.2e-05 0.0005 20.0 0.4 1 23 595 617 595 617 0.98
12 15 0.005 0.22 11.7 0.2 3 23 625 645 623 645 0.97
13 15 0.00016 0.0069 16.5 0.3 1 23 651 673 651 674 0.95
14 15 0.046 2 8.7 1.5 1 23 688 710 688 710 0.96
15 15 0.0017 0.075 13.2 0.1 1 20 1083 1102 1083 1105 0.94

Sequence Information

Coding Sequence
ATGGAGGATAATTTTGCATTAAGTTGGGAGGATTCAACAACGGTTGTCCAAGGTGAAGAAGTAATTTGTAgtatagaaaatgaaatattaccGAGTGAATCGGAAGAATTTACTGGTGTCGTCTGTAGTGATGAATCACcaaccaaacaacaacaacaacaatcacaaatTGAAGAAGTAGTAATAGGAGATGGTGATCAAGAAGAAGTTGTAGAACAAGAgaatattgtttatataacTGAAGATAATGTATTGGTTATGGATTCGGGTGATGGtactggtggtggtagtgctggtgttgttgttgaaggtgaacaaacaccaacaactgataatgattttcaacaacaatttatggATTGTCAAGTAACTGAAGAGATTGTAACAGAACAATGGGATGAAAGTTGTCCAGAAGAgattgttgttggtagtgAAGAAGCTGTTGGTGGTACCGAAGAACAAACAAATGAAGATTTTGATATACCATTACCAACTGATCAAGATGAATATACAGCATCAAGACCATATCCATGTGATTTTTGTAGTCGACGTTTTCGTAAAAAAGCGAATTTAATGAATCATATGGTTGCACATCAAACAGATCGTCCACATGGTTGTAATTTATGTGGTGTACGTTATATAAGAAAATGTGatttaatgaatcatttaaaaattcatgcTTATATACCGGAAACTGATGgtttagaagaagaagaaacacaacaattaGATGAATCAGATCAAGAGAAACGTATTAGTAAACGAACAAAACCATTTTCACGACGTAATAAACGAAAAGTTAAAGAGgaatatgaaaattatgaaGGTGATGAAACTGGTGCATCCAGTTCCAAATCGTATAATTATGTTGATGAAGATATGCGTTTAATGGAAGCAATGGAGAATAATGTTAAACCTGATTATACTGAATATAATGAATATATAACAGAGAATCAAACTGTTGAAGTACGTTATCCAATAACAGATCCACGTAAACCGTTTGTATGTCAACATTGTGGCGTTGGTTTTGCTAGAGAGAAAGCATTAGCATCACATGCTCGTATACATGGTGGTGATAGTCCATTTGAATGTCAGAAATGTGGTGAAATGTTTTGGGATTTAGCATTAATGCGTGAACATGTACGTGCAAAACATGGTGGTGATATTGATGATCTTATTGAtgagaatgatgatgatgatgatgaagaagatgatgattattCGGAAGAAGAGACAAAATATGGTACATTTTATTGTTCTGTATGTGGTTTATCATTTCATCGACAAGATAATTTGAAACGTCATCAACGTGTCCATATCAAAGAAGAATATATAAATGATCATGAATTTGGACATATATGTAATGTATGTGGTGAATCATTCCCTGGTGCATTAGAATTATTAGCACATGCTGAAGTACATGCACGTGGTTCGGAACATCGTTGTATGATATGTGGTGAAGTATGTACAGATGACCAAGCAGTTGCTGCACATGTGCAATCAAAACATGGTAAAACATTACCATCAAATACGTGTATGTTATGTGGACGGACATGTAAAGACCGTCgtacattattaaaacattcatGGGAACATTCAAAAGAGAAAAGTTTTGCATGTTCGAAATGTGCAAAAACATTTCATAATAAAGCTCGATTAAAACGTCATATGTTATCGCATCGTAATAAAGTTGTTTCATGTGATGTATGTGGTGAAGAGTTCCCTGATGGACGTTCATTGATGAATCATCGACATAGTCATAGTAGTTTATCTGGACGACAATTTCCATGTCGTGAATGTGGTAAAACATTTGGTTCACGTAGTTCCCAACAGATCCATATACGAATACATACCGGTGAACGGCCGTATGGTTGTCGATTTTGTTGGAAAGCATTTGCCGATGGTGGTACATTAAGAAAACATGAACGTATACATACCGGTGAGAAACCGTATGCATGTGCTGTATGTCCACGTGCATTCAATCAACGAGTTGTTTTAAGAGAACATATACGTTCACATCATTCAGGACCTGATCCGAAATATTCACATAGTGTTACACCGTATTGTTGTTCAGTATGTTCGGATATGTTTGCCACATCACAAGATCTAATTGTACATTTAATACATCATTGCGATATGAATACAGCTATGAAACGGCAACCACAAGTTGGTCCAAGAAAATATAAACGTCGACGAAAATTGAAACCACACGAATTGGAAATGATATCAAGTAAAGTTGATGATGaaatggatgatgatgatgaacaacaacaacaacaacaacaacaacaacaacaacagcaagaGCAATCACcacatcatcaacaaccaccacaacaacaacaaaatatatattcagATTCGGAAGAGGATCGTGAAATACGTAAAAAAGGTAATAAGAGATTCAAGAAAAATTCCCCGAAAGCAAATCTAAATGAAACAtacaatgatttttataatagttgttcatcaacaattgaaaatataaattcaatagttaattcaaaaacaacaaattcaaagaCAAAACGTAAAACTAAAAATGAAACTACAGTACCATCACGTCCGAAAATGATCCATACACAAAAGACACGTGTACCAGTTGATACCGGTGAAGATGGTAAAGTACGACATAAAACTAAAACATTAGTAACACGTACACAACCAACTGAATTGAAATCATCAAGTGGTGATCGTATACGGCCACGTACAAAGAATGTCAGTTATCATATActgaataatgaaaaattaccattgGCTACGTTCCCAGAAGATGATCAAGCtgttagtaatttattaaaagagaatTTAAATGATGAACAACAGACAACCAATAATGGTGATGTTGTAATGGAACAACCAACTGAACAAACACCAGAAGTTGCATCTGAACAAGTTATTGAAAGTGATAATGGTGCATTtccaacaaatattattaaaataacatcaACTCCGACacaattacataatttacGTCCTGGTCGTCATTTAATTGTACCTGGTAGTAAAGTTGTACGTTTAGTTAAAGGTGGTATGattgtaacaaaaacaaaagagaaagaaaagaaaactaataatGAACCGGAAAATATTTTACCAGATGTTGAAACATCTACAacagataatgatgataatgttaataataataataaaaataaaaataagaaaaaaatcaaacggGAAATTGTTGATCCAAGTCCATTACATGAACTAGCTGAAATATCAATGCAACATGcacaaaatatatttaaatgtgaaaTGTGTAGTGCAGTGTTCTCTGATAGAAGTAAACTATTGGATCATGTGCCCATACATATATGA
Protein Sequence
MEDNFALSWEDSTTVVQGEEVICSIENEILPSESEEFTGVVCSDESPTKQQQQQSQIEEVVIGDGDQEEVVEQENIVYITEDNVLVMDSGDGTGGGSAGVVVEGEQTPTTDNDFQQQFMDCQVTEEIVTEQWDESCPEEIVVGSEEAVGGTEEQTNEDFDIPLPTDQDEYTASRPYPCDFCSRRFRKKANLMNHMVAHQTDRPHGCNLCGVRYIRKCDLMNHLKIHAYIPETDGLEEEETQQLDESDQEKRISKRTKPFSRRNKRKVKEEYENYEGDETGASSSKSYNYVDEDMRLMEAMENNVKPDYTEYNEYITENQTVEVRYPITDPRKPFVCQHCGVGFAREKALASHARIHGGDSPFECQKCGEMFWDLALMREHVRAKHGGDIDDLIDENDDDDDEEDDDYSEEETKYGTFYCSVCGLSFHRQDNLKRHQRVHIKEEYINDHEFGHICNVCGESFPGALELLAHAEVHARGSEHRCMICGEVCTDDQAVAAHVQSKHGKTLPSNTCMLCGRTCKDRRTLLKHSWEHSKEKSFACSKCAKTFHNKARLKRHMLSHRNKVVSCDVCGEEFPDGRSLMNHRHSHSSLSGRQFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACAVCPRAFNQRVVLREHIRSHHSGPDPKYSHSVTPYCCSVCSDMFATSQDLIVHLIHHCDMNTAMKRQPQVGPRKYKRRRKLKPHELEMISSKVDDEMDDDDEQQQQQQQQQQQQQEQSPHHQQPPQQQQNIYSDSEEDREIRKKGNKRFKKNSPKANLNETYNDFYNSCSSTIENINSIVNSKTTNSKTKRKTKNETTVPSRPKMIHTQKTRVPVDTGEDGKVRHKTKTLVTRTQPTELKSSSGDRIRPRTKNVSYHILNNEKLPLATFPEDDQAVSNLLKENLNDEQQTTNNGDVVMEQPTEQTPEVASEQVIESDNGAFPTNIIKITSTPTQLHNLRPGRHLIVPGSKVVRLVKGGMIVTKTKEKEKKTNNEPENILPDVETSTTDNDDNVNNNNKNKNKKKIKREIVDPSPLHELAEISMQHAQNIFKCEMCSAVFSDRSKLLDHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00987317;
90% Identity
-
80% Identity
-