Basic Information

Insect: Iphiclides podalirius
Gene Symbol: ZFHX3
Assembly: GCA_933534255.1
Location: OW152823.1:9378575-9385248[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.4 33 5.5 2.5 1 23 47 70 47 70 0.95

2 15 0.049 4.1 8.3 0.0 1 23 77 100 77 100 0.95

3 15 0.0046 0.38 11.5 4.1 2 22 155 175 155 178 0.91

4 15 0.53 44 5.1 1.1 1 23 190 215 190 215 0.91

5 15 0.0082 0.69 10.7 1.3 1 23 233 255 233 255 0.97

6 15 0.00099 0.083 13.6 0.3 2 23 262 284 261 284 0.96

7 15 0.00018 0.015 16.0 3.1 1 23 390 414 390 414 0.92

8 15 0.0073 0.61 10.9 0.7 1 22 434 455 434 458 0.89

9 15 0.00073 0.061 14.1 0.2 1 23 505 529 505 529 0.93

10 15 0.58 49 4.9 0.1 3 21 604 622 603 623 0.91

11 15 0.53 45 5.0 3.5 2 19 713 730 712 735 0.91

12 15 1.9e-05 0.0016 19.0 2.9 1 23 1240 1262 1240 1262 0.99

13 15 0.00049 0.041 14.6 0.3 1 23 1349 1371 1349 1371 0.98

14 15 0.0046 0.39 11.5 0.4 2 23 1509 1531 1508 1531 0.97

15 15 0.21 17 6.3 1.6 2 22 1760 1780 1760 1783 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.4	33	5.5	2.5	1	23	47	70	47	70	0.95
2	15	0.049	4.1	8.3	0.0	1	23	77	100	77	100	0.95
3	15	0.0046	0.38	11.5	4.1	2	22	155	175	155	178	0.91
4	15	0.53	44	5.1	1.1	1	23	190	215	190	215	0.91
5	15	0.0082	0.69	10.7	1.3	1	23	233	255	233	255	0.97
6	15	0.00099	0.083	13.6	0.3	2	23	262	284	261	284	0.96
7	15	0.00018	0.015	16.0	3.1	1	23	390	414	390	414	0.92
8	15	0.0073	0.61	10.9	0.7	1	22	434	455	434	458	0.89
9	15	0.00073	0.061	14.1	0.2	1	23	505	529	505	529	0.93
10	15	0.58	49	4.9	0.1	3	21	604	622	603	623	0.91
11	15	0.53	45	5.0	3.5	2	19	713	730	712	735	0.91
12	15	1.9e-05	0.0016	19.0	2.9	1	23	1240	1262	1240	1262	0.99
13	15	0.00049	0.041	14.6	0.3	1	23	1349	1371	1349	1371	0.98
14	15	0.0046	0.39	11.5	0.4	2	23	1509	1531	1508	1531	0.97
15	15	0.21	17	6.3	1.6	2	22	1760	1780	1760	1783	0.88

Sequence Information

Coding Sequence: ATGATGCGATTCTTGGAGCAGCACCAACACCAGCACCAGCAGCAACAGCAGCAACAACAACAACAACAGCCGCCGCTCCAGCAACAGCCCCAACAAGGGCCGAGCGAACGCGAAGACGATCACGACACTCCCGGACAACACGCCTGCCCATACTGCAACTTTAGTTGCGCCGCCGAATCCAGACTGCACGCGCACGTCACCACCGTGCACGGAGACACGGCGCGTCATTTCATCTGCCCTCTATGCCAGGATGCGTTCAAAGAGCGGCCGGCCCTAGAAAGGCATGTCATGCAAATACATTCGGTCAACTCCGAGGGCCTACAGAGACTGCTACTCCTTGTTGACCAAAGCCATTGGCTGAATGGGGGATCACACCCGCAGAGGGAGGAAACCCGACAAGCAGAGGACGACCGCGAGATCTCTTCGCCGCGCTCGGAGGGGAGCGTGGACGGCGAAACCGAGCGATGCTCCACTTGCAACAGGACGTTCCGCAACGTCGACGAACTCTGCCATCACCAGAACGAATCGGGCCATTTGGAACTGAAGCAGACACCGCAAGGCCCCGGATACTTCTGTTGGAAGAAAGGCTGCAACAGATACTTCGACGCGGCGCACGCCCTACAAAATCACTTTAGGGAAGCTCACGCTCGCAACTCTATTGCGAACATGTCGGTGTCCGAAAAACACGTATATAAATACAGGTGTAATCAATGCAGCTTAGCTTTCAAAACCATTGAGAAATTACAATTACACTCTCAATATCACGTCATAAGGGACGCAACAAAATGTGTGCTATGCGGACGAAGCTTCCGTTCTGTCTTAGCTCTACAGAAACATGTCGAGACCTCTCACTCTGAGCTCTCGGAAGAAGATCTCGCTGCGTTCAAAAGGAGTCTCGCATCAAATCCTTTACTACAAGCGAACCAGGGCACTGCACTAGATCCTGCTACGGCTGAATTATTACGCAAAGAAGCTCTTAGGACTCCAGACGATGAGCTAGGTGAGATGGAAGATCGCGATTCGAGCGCCACCGCTGCTGACGAATCGGGCCATAACGATGCCGAAAACTCCGACGATTCGATAATATATAAAGATCAACAATTTTTGGAAGACTACTTAAACTCGCAGGCAATGGCCGAAGACTCATACAATGACCCGAACAGGAAATATAAATGTCACCGATGCAAAGTGGCATTCACCCGCCAGTCTTATTTAACTGCTCACAATAAAACGCTTTTGCACAGAAAAGGCGAAAAGCTAACATACCCGATGGAAAAATACCTCGATCCAAATAGACCTTTCAAATGCGATGTATGCAAGGAGTCGTTTACACAAAAGAATATTTTGCTTGTTCATTACAACAGTGTTAGTCATTTGCACAAATTAAAGAGGGCCATGCAAGAACAACAGAACAATAACAACCCTCCCGTATCACCCGGAGCTGGGACAGCGCCCTCCAATTTGACGCTCACCCCAAAAAGTACATCTAGCGAAGAAGACGATCGTAAACGTTATAAGTGCAATATATGCAAAGTAGCTTACACGCAGGGCAGCACCCTAGACATTCACATGAGATCGGTGCTGCATCAAACGCGAGCGGGTAAGTTGCAAGAGCTCGCCGCGGCCGGCCACGTGGACTTGACGCGTCCTTTAGTCGAGCAACCCGATAGAACGGACCCCGCGAAAATATTACAAGACGTATTGTCGCCGAAAAATACATCCCCTTCTTCGACGAGCAGCGGGGGGCCCCGCTCCTCGCCCCCCGCGCGCCCAGGTAGCCCTCGCTCCCCTCGCGCAGGTAGCGCCTCGTGCGATCGGTGCCACGCGTCATTTCCTAACGTTGAGCTACTCGACGCACACCGTGCGACCTCATGTCCGTTTGGCGATGCGCGGGCGCATTCGCCGCTAGGTGACGCGGAGCAAGCTGCGCTGGACGAGATGGTCGCCAAGGGCAACCCGCCCAAACGAAACTCACAAATGTATAAGCAGCTTTTGGAGACATTCGGCTTCGATCTCGTCATGCAATACAATGAGAATCAACGGCGGAAATTGCAAGAGGAGCGCGAAATGGCGCGCGCGCCCAGCCCGCCGCCCCCGCCCCCTGAAGAAAAGCCTCCGGATGGGGAAACGAAATCGACGTGTCAACATTGTAACAAGGAATTCTCTAGTGTGTTCGTTTTAAAAACTCATTGTGAAGAAGTGCATAAAGATAAAGTTCCGCTCGAGTTTTTAGAGCAATTCGCGGAGCAGTTCAAATCAGAATATGAGAGGAAATCGGGAGCGCCAAATTCGCCCCGTGCGGCATCGCCCGCGCCGCAGGACGAGAGGTCGCCTTCGCCGCGGGGCGAGGCTAATAACAGCTTCAATGAAAACGGTACTGGTCCGGGTGATGCGCAGGCAGGAGCCCTGCTAGCGGCTCAGGTGCAAGAAATGCAAGCTGCACTCAACATGCTACAATTACAGCAACAGCTCGGACAGCTGCACCCTATGATGGCTCAGATGTTGTCCCTGGGACTTCCTTTGGGCTTGAACGTCGGAGCTCTGGCTGCTATGAACCTGCAGCCACCGCTGGTTCCTCTGATGCTTCCACCTCCACCTTTCGACGCAATGCCATTCGCACACGACGCGCAAATTAAACAACAGCAGCTATTGCAGCAACAGCAACAGGCGAATGCTGCGGCCGGACAAAAGCGTGCGCGCACTCGTATAACGGATGAACAATTGAAAATACTACGAGCGCACTTCGACATTAATAATTCTCCCAGCGACGAAGCAATTGCGAAGATGGCTCAGCAGTCAGGTTTAGCGACAAAAGTTATCAAGCACTGGTTCCGGAACACTCTGTTTAAGGAGCGTCAACGCAATAAGGACTCGCCTTATAACTTTAATAATCCTCCTTCAACAACACTTAATCTCGAAGAATACGAGAAAACTGGCGAAGCCAAAGTGACTCCTTTGGATTCATCGGCGAGTTCTGATGAAGGCAAACCACCACCTGAAAAAAAAGCAAAAACTGAAGACACTACACCAATAACACATCAGGAAGTCAAATCTGAACCAAATGACGAACCGACAATGGAAGAGAAATATAATTCTTATGACGACAGACATCAAGAGGATAAGAGTTTTATATTTCCTCAGGCCCCATTACAAAGTCCGGCATTAAATAATTCTGATCATCAACAAAATATTTCACGACCACAGACACCAACACATTTGTCGCTAAATTCATTAATCCAGTCTCAGTTAGATTCAATACCGGCGACAAGTATACCACAACCACCACATCCATCTATGTTGCCGCCAAAATTAAATCCAAACTTCACGTCCCCAAACTCCGCGCCCCCGAACGTCCTGCCTTTGACCCCAAATCGCAGCCTGAGTCCTGGCAGAGGACCGGCGGATTTCGGACTTTCCGGGGGCAACTCGAATGGATCCAACAGCTCGGGGTCTTCTGGCAAACGCGCCAACAGAACTAGATTCACTGATTATCAAATCAAAGTACTACAAGAATTTTTTGAGAACAACGCCTATCCTAAAGATGATGACTTAGAATATCTTTCAAAACTCCTTGGACTAAGTCCTAGAGTTATTGTGGTGTGGTTTCAAAACGCTCGCCAAAAAGCACGAAAAGTTTATGAAAATCAGCCAGCAGCAGAACCACCCACTGGAGCAACCGATGATGCAAATAGATTTCAACGTACTCCTGGTTTAAATTATCAATGCAAGAAATGCCAGTTAGTGTTTCAGAGATACTATGAATTGATAAGACATCAGAAAACACATTGTTTTAAAGAAGAAGACGCGAAGCGTTCAGCTCAAGCTCAGGCAGCTGCCGCCCAAGTAGCTGCTACTCTGAGTAGTGAAGATTCAAATTCAAGCACAGTTGAACATCATGTGCCTCACGTACCAGTTTCTCCTGCTCCACCTCGTACTCCAACACCCGCTGCCCCTAACTACCCAGTATCGCCGGCTCCACAGGCCCCTCTTACACCAGTAACTCCCATTACTCATCAGCCACGAACCGAAGAGAAAGACGATAATTTTCAATGCGATAAATGCAACCTTGTCTTCCCTCGATTTGATTTATGGCGGGAACATCAACTTGTTCATATAATGAACCCAAACTTATTTCCCACGTATCCACCAGATTCACCATTTGGAATACTTCAACAACACGCACAGTTACAACAATTAAACGCCACGCTTGCTAATGAGGAATCACGTCATCCTTTAGTGGCAGCACTTAACCAACAAGTTGCGAAAAGGAAATTTGATGAATTTGAAGAAATAGACACAGGAGAACAACCAAAAGACAAACGGTTAAGAACTACCATTTTGCCAGAACAATTAGATTACTTATACCAAAAGTATCAAATAGAGTCAAATCCATCACGAAAAATGTTGGAAAATATTGCTCGAGAAGTGGGTTTAAAAAAAAGGGTGGTACAAGTTTGGTTTCAAAATACAAGAGCTCGGGAGAGAAAAGGCCAATTTCGGGCCCATGCACAGGTTATCAATAAACGATGTCCCTTTTGTCCTGCGTTATTTAAAGTGAAGAGTGCTTTAGAGAGCCACTTAAGCACCAAACACGCAGATCAGTGTGCACGAGGTGAAATAAACGTAGATGCTCTACCAGATGAAGAATTAAGCACCGAATCAACCCCAAGCTTTGGTTCTCAACAAAGTGATAGGCAGCAAAATTTTTCCCAAGGGGGGGCTCCCATGTTGCCCCCTATTTTCCCGCCTTTTCACTCAGACATGGAGAAATTTATCAAGCAGTACAGTGAAGAATCAATGAAACGCTACGTAAGTGAATTGCAAGCTCACGCTGTCGCGCAACAAAATGGCGCTAATAATGAGTCTGCAGAAAGACAATTATCTCATGGAAAATCAGAAATACCATTAGATCTCAGCAAGCCAGTAGACCTGTCACGCCCAGGATCGGATGCAGATGAACGCTCAGACACTGCGTCAGAAACAATGGAGTTCTACGAGGAAGATGAGCCGACGTCACCATTACCAGGTCAACAACAAACGACCCGGCCACCTGGAAAACGCTTCCGCACTCAAATGTCATCAGTACAAGTAAAAATAATGAAGTCTTTGTTCAACGACTACAAAACACCAACAATGGCGGAGTGTGAAGCCTTGGGCCGAGAAATTGGCTTACCCAAGCGCGTGGTGCAAGTATGGTTCCAGAATGCACGTGCCAAAGAAAAGAAAGCACGACTAGCGGCAGGCTTGTCGGAAGTGTCGGACGCACCTCCGCCGGAGGAATGTCGCGTTTGCGATTTTAAGTACAGCCACAAGTATTCAGTGCAAGATCACGTGTTCACGCGCGGGCACATCGCAGCTGTGCGCGCGCGGTTAGAGAGCGGCGTTGGCGGTGCGGACGACGGCACGCTGGCCCTCATGCAGATGGCGGCACGGCTCGAGAGCGGCATCGGCAGCGAACTGCACAACGCTTTTCTGAGACCCCAACTCGCCGGCAACGGTGAGTGCACCACTTGA
Protein Sequence: MMRFLEQHQHQHQQQQQQQQQQQPPLQQQPQQGPSEREDDHDTPGQHACPYCNFSCAAESRLHAHVTTVHGDTARHFICPLCQDAFKERPALERHVMQIHSVNSEGLQRLLLLVDQSHWLNGGSHPQREETRQAEDDREISSPRSEGSVDGETERCSTCNRTFRNVDELCHHQNESGHLELKQTPQGPGYFCWKKGCNRYFDAAHALQNHFREAHARNSIANMSVSEKHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRDATKCVLCGRSFRSVLALQKHVETSHSELSEEDLAAFKRSLASNPLLQANQGTALDPATAELLRKEALRTPDDELGEMEDRDSSATAADESGHNDAENSDDSIIYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNPPVSPGAGTAPSNLTLTPKSTSSEEDDRKRYKCNICKVAYTQGSTLDIHMRSVLHQTRAGKLQELAAAGHVDLTRPLVEQPDRTDPAKILQDVLSPKNTSPSSTSSGGPRSSPPARPGSPRSPRAGSASCDRCHASFPNVELLDAHRATSCPFGDARAHSPLGDAEQAALDEMVAKGNPPKRNSQMYKQLLETFGFDLVMQYNENQRRKLQEEREMARAPSPPPPPPEEKPPDGETKSTCQHCNKEFSSVFVLKTHCEEVHKDKVPLEFLEQFAEQFKSEYERKSGAPNSPRAASPAPQDERSPSPRGEANNSFNENGTGPGDAQAGALLAAQVQEMQAALNMLQLQQQLGQLHPMMAQMLSLGLPLGLNVGALAAMNLQPPLVPLMLPPPPFDAMPFAHDAQIKQQQLLQQQQQANAAAGQKRARTRITDEQLKILRAHFDINNSPSDEAIAKMAQQSGLATKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLDSSASSDEGKPPPEKKAKTEDTTPITHQEVKSEPNDEPTMEEKYNSYDDRHQEDKSFIFPQAPLQSPALNNSDHQQNISRPQTPTHLSLNSLIQSQLDSIPATSIPQPPHPSMLPPKLNPNFTSPNSAPPNVLPLTPNRSLSPGRGPADFGLSGGNSNGSNSSGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAAEPPTGATDDANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSTVEHHVPHVPVSPAPPRTPTPAAPNYPVSPAPQAPLTPVTPITHQPRTEEKDDNFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNATLANEESRHPLVAALNQQVAKRKFDEFEEIDTGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLSTKHADQCARGEINVDALPDEELSTESTPSFGSQQSDRQQNFSQGGAPMLPPIFPPFHSDMEKFIKQYSEESMKRYVSELQAHAVAQQNGANNESAERQLSHGKSEIPLDLSKPVDLSRPGSDADERSDTASETMEFYEEDEPTSPLPGQQQTTRPPGKRFRTQMSSVQVKIMKSLFNDYKTPTMAECEALGREIGLPKRVVQVWFQNARAKEKKARLAAGLSEVSDAPPPEECRVCDFKYSHKYSVQDHVFTRGHIAAVRARLESGVGGADDGTLALMQMAARLESGIGSELHNAFLRPQLAGNGECTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00840144;
90% Identity: iTF_01495287;
80% Identity: iTF_00840144;