Ipod021262.1
Basic Information
- Insect
- Iphiclides podalirius
- Gene Symbol
- gtf3a
- Assembly
- GCA_933534255.1
- Location
- OW152842.1:4429675-4444075[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 3.2e-05 0.0027 18.3 2.9 1 23 16 38 16 38 0.98 2 12 0.0077 0.65 10.8 4.8 1 23 45 68 45 68 0.93 3 12 4.1e-06 0.00034 21.1 0.9 2 23 77 99 76 99 0.95 4 12 7.1e-05 0.006 17.2 0.2 2 23 106 127 103 127 0.94 5 12 0.01 0.84 10.5 2.0 1 23 133 157 133 157 0.92 6 12 0.00055 0.046 14.5 1.2 1 23 163 185 163 185 0.96 7 12 0.0022 0.19 12.5 0.1 2 23 193 215 193 215 0.97 8 12 0.00098 0.082 13.6 0.3 1 23 220 243 220 243 0.97 9 12 0.0055 0.46 11.3 0.8 2 20 250 268 249 269 0.95 10 12 8.8 7.3e+02 1.2 6.2 1 21 469 489 469 491 0.89 11 12 0.086 7.2 7.5 0.4 2 23 502 522 501 522 0.90 12 12 0.00016 0.013 16.2 0.9 1 23 645 667 645 667 0.98
Sequence Information
- Coding Sequence
- ATGGCGCCCATTAGGCGAGAGTTTACACGGGCTGACGTAAAGCCCTTCGAATGCTCGATGTGCGACTACGCGTGCCGTGACAGTTCCACGCTGAGGAAGCACCAGGATAGGCACTTGGGCAAGAAGAAAATGTACCCGTGCAAATATTGCAGCAGGCAGTGTAAATCGAAGAAGTCCCTCAAACTGCACACGGAGGAGAGGCACTTCGGCGTGGACGTGAACAGGATACCGTGCGACATCTGCGGCAAGATGTTTAAGAGCACCACCCACTTGACGAACCACGTGAACAGGGTGCACGCGCGCCGCTACTCGTGCAAGTGCGAGATATGCGGCGCCGCCATCAGCGCGAAGGGCAACCTGCTCGCACACATGCGCACACATACGGACATAACGCCGTACAAGTGTGCGCACCCCAGTTGCGGCAAGCTGTTCAAGCGGATGGACTATCTGAAGAAGCACAGCATCCTTCACCGCCCCGAGCGTCACTACGCCTGCGACATCTGCGGCCACCTCTTCTCGCGGAAGACTCGGCTCAACAGCCACCTGGCCCAGCACCAGCCCAAGGTCAAGTCGGCCCAGTGCGACCTCTGTGGGGTCCGCTTCTACAACGCCAACTACGTGGCGGCGCACATGCTCCGCAAGCACAGCGGCCGCCGTTACGAGTGCGACGAGTGCGGTTTCCGCACGCCGAACAAGCCGAGCCTCGTGATGCACATCAAGCACGGCCACGAAACGGAGAACGGGAAAGTATGCCAGATATGCCGTAGGGGTTTCAAGAACAACCTGCATCTCAGACAACACTACTGGAACGCGCATTGCGTCCAATACAAGAAGGTCAGACGGCGAAGGCGCAAGAAGGAGATAGAGGAGACCGTCATAAAACAGGAGATGGACACTATACCAGAAATAGATCTGCTAGAAGTTCACAAAGAGGAGATAATGTCTGACGTGGAAGCAGATTCTCAGAGCGGCGCAGAAGTGGAGTACACGAAACGGGAGTTCCGTGATGATGAGAGGATGCTGGAAGCCGGTGACGGTGAAGATGAGGAGCGTCCAGAGATCTCCACCGAAGTGGTGGTGGAGAAGCTCGAGGAAGTCAGCGGCAAAGTCGAGGAAGCGACGGAAGCCCAGCTCCTGGTGGAAGTAGACACCGGACTGGAGGAGAACGCGAAGAGAGAGCTGGAGACGCTCCTGTCTAAGGCGAGAAGAGAGAAGAAGTTGGCGGAGTTGGAGGAGACCAGGAGGGATTACAACGAGAGGATAAGACGGGCTATCGGCGAACAACCGAAGACAGACAAATCATTGAACGATAATGACGCGGCCAGTGAGAAAGAGACGGATGGAAACGACAACGAAATCGACAAAGCGGCGGATAGGAAGGGTGGGAAGTTGAAAATCAACACTCACCAATGCTACGTCTGTTTCAAGCTGTTCCCAACGAAGCTCGCCCTGACGGAGCACTGCCAGCACCACTTCGACGTTTGCGGCGGCGTGATGCTGAAGAAGTGCCCGATGTGCGATTACGCCACCAACCTGGACCTGAGGAGGCACATGAGGCTGGTCCACGGCGTCCACGTGCGGCTGAAGCACCCGAGGATCAAACAGACGAAGGAGAACGGCTCCAAGTTCTACTACGACCTCGGCAACCTTGGCGATGTGGAGGTCATACCCAGCGCGCGGAACCTTAACAGGCGCGAGTGCGCGAAGATCGACCAGCGGAGCAGGCGCGAGAGGGAGATGACGGTGGCCAAGAAGAAGCTGGTCAAGAGGGGGTCCGAGTGGGTGGTGGAAACGGAAAGGCTCTCCGTCGAGGAGTTCCTCCTGCCCGAGCTGGCGGCGCAGGGCGACACCGGCCCGGAAGTCGGCGACGACTACTTGGCCAGGCTGAAGCGACTCAGCCGGCTGGCGAAAGCCCACGGCGCCAAGATGCTGTTCCCGTGCGACGGCTGCCCGAAGATATGCCAGACCCTCAGCGCCCTCAAGCTGCACACGCGCCGCCACGACCCGAACAAGAAGCCGTACAAGCCGAAGATATGGAAGCACAAGACGAAAACGCAGAATGACAGCGGGAGAACGGGGAACGGAGCAGGCGACGACGCCGAGGGAAGAGTAGGAGAAGGAAAATCGCGGCCGACGTCCTGCAAACAAGCAAAGGCAGCGCTAACGGACAAAAGAGAGACGGTAGCAGAGGCTGGGGAAGACGCCGAGGGTGGTTTTGGTGGGGCGGCGCAAAGCGCTCAGCAGTCAGCGGGGGACACGGGGGGAAGTGCTCGTTCTGAAGAGGCGGTGGGAGGGGGCGGGGCCTCCGCCAACCGGCACGCCGAGCCGCGCCCGATAGTGAACCGCCACAGATGCGACCCCGCCCTGAGGGAGTTCTACGCGCGGAACGTCAGGGGCGGCGACGTGGAGTTCCACCAGTTCCTGAAGATCTACAACCGGATATCGCGCGAGGGGGGGCCGCCAGAGGACGCCGCCTGTTCCCCCCCCATAGAGGGGCCTCCGCGGCGGGGGAAGCCCCGGCCGGTGGGAGTGCGCAAAGCCGCGCCGAACCCTCACACCAGGGTCGTGAGAGTCACCAGGAGGGAGCATTTGGCGCGGCTGGAGGCGAGGAGCAGACTGAGGCGCGAGCTCGAAGCCAGGTCGTCGGGAGCTCGCGCGTGA
- Protein Sequence
- MAPIRREFTRADVKPFECSMCDYACRDSSTLRKHQDRHLGKKKMYPCKYCSRQCKSKKSLKLHTEERHFGVDVNRIPCDICGKMFKSTTHLTNHVNRVHARRYSCKCEICGAAISAKGNLLAHMRTHTDITPYKCAHPSCGKLFKRMDYLKKHSILHRPERHYACDICGHLFSRKTRLNSHLAQHQPKVKSAQCDLCGVRFYNANYVAAHMLRKHSGRRYECDECGFRTPNKPSLVMHIKHGHETENGKVCQICRRGFKNNLHLRQHYWNAHCVQYKKVRRRRRKKEIEETVIKQEMDTIPEIDLLEVHKEEIMSDVEADSQSGAEVEYTKREFRDDERMLEAGDGEDEERPEISTEVVVEKLEEVSGKVEEATEAQLLVEVDTGLEENAKRELETLLSKARREKKLAELEETRRDYNERIRRAIGEQPKTDKSLNDNDAASEKETDGNDNEIDKAADRKGGKLKINTHQCYVCFKLFPTKLALTEHCQHHFDVCGGVMLKKCPMCDYATNLDLRRHMRLVHGVHVRLKHPRIKQTKENGSKFYYDLGNLGDVEVIPSARNLNRRECAKIDQRSRREREMTVAKKKLVKRGSEWVVETERLSVEEFLLPELAAQGDTGPEVGDDYLARLKRLSRLAKAHGAKMLFPCDGCPKICQTLSALKLHTRRHDPNKKPYKPKIWKHKTKTQNDSGRTGNGAGDDAEGRVGEGKSRPTSCKQAKAALTDKRETVAEAGEDAEGGFGGAAQSAQQSAGDTGGSARSEEAVGGGGASANRHAEPRPIVNRHRCDPALREFYARNVRGGDVEFHQFLKIYNRISREGGPPEDAACSPPIEGPPRRGKPRPVGVRKAAPNPHTRVVRVTRREHLARLEARSRLRRELEARSSGARA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -