Basic Information

Gene Symbol
-
Assembly
GCA_946894085.1
Location
CAMPPJ020000274.1:338667-340593[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.024 1.9 10.0 1.6 1 23 46 69 46 69 0.98
2 9 0.89 73 5.0 0.1 2 23 98 120 97 120 0.92
3 9 0.092 7.5 8.1 4.7 2 23 141 162 140 162 0.96
4 9 9.2e-05 0.0075 17.6 1.7 3 23 168 189 167 189 0.97
5 9 0.0043 0.35 12.3 2.0 2 23 199 221 199 221 0.93
6 9 0.00037 0.03 15.7 1.6 1 23 227 250 227 250 0.96
7 9 0.011 0.92 11.0 0.5 1 23 256 278 256 278 0.95
8 9 2.1e-06 0.00017 22.7 0.4 1 23 284 306 284 306 0.98
9 9 1.8e-05 0.0015 19.8 3.6 2 23 313 334 312 335 0.94

Sequence Information

Coding Sequence
ATGTTCTACTGTATGGTGTATCCTTGTTGCCACATTGAACATGGACAAAGAACGAATACGCTCGGCGTGATCCGAAACGTCGTCTGCGTCCTCAAGAACTCCACGGTGTTGCCGTTCAGCTGGCATCTAAATAAATACAAATGCTTCTTTTGTATCGCTGGCTTCGTGGATCATTCCGACATAAGGCAGCATATGCGCAAAGAGCACAGTGCCCCCAACCTCGACCTGGTAGTCAAACATCACCTGATCTCTCGCCAAGCGGCCAACGTCAAAGTCGACCTATCAGACATAACCTGCAAGCTGTGCGCGCAGAACATAATCACCTTGGATAGCCTAGTGCAGCATTTAATAGAAAAACACAAGATCAACTACGACAGGAATGTTGAATGTAAGCTACAGGGCTTCTATTTGTCTGAACTGAAGTGTTCGAAGTGCAATGAGAAGTTCGAGTTCTTCCAAACACTCCTCCATCACTCGAACCGGCACAGCGCCCCCTGGCTCTGTCACGACTGCGGCAGCAGCTTCTCGAACAAGGCGCTGATGCGTCAACACATACTGCGCACCCACCTGGCGGTTAAAAAGGTGTACCAAAGAAAGTGCAGACACTGTCCGGAGAGGTTCAAGACGCCTCACTTGCGCTGGTCgcacatggctgccgcgcacgacttaaaagtagactataagtgcgagcaatgcgggatgggtttccacatcaagagccgactgacgaggcacgtcagggcaactcacctcaaggagcgcaacttcgcctgcgaagtgtgcggggacaggttcttcaattcgaatctgctcaaactgcataaagtccggcactcccaggcgaggccgttcgagtgtgaagtgtgcaagaaggagttcgcgcgtaagaagaatctagatatacacgtgcgtatacatacggacgacagacggtgcgtgtgcaagctgtgtggcaagaagtttatacagactgctagcttgaaaCTGCACCTCAGGGTCCATCATGCAAATAAGTAA
Protein Sequence
MFYCMVYPCCHIEHGQRTNTLGVIRNVVCVLKNSTVLPFSWHLNKYKCFFCIAGFVDHSDIRQHMRKEHSAPNLDLVVKHHLISRQAANVKVDLSDITCKLCAQNIITLDSLVQHLIEKHKINYDRNVECKLQGFYLSELKCSKCNEKFEFFQTLLHHSNRHSAPWLCHDCGSSFSNKALMRQHILRTHLAVKKVYQRKCRHCPERFKTPHLRWSHMAAAHDLKVDYKCEQCGMGFHIKSRLTRHVRATHLKERNFACEVCGDRFFNSNLLKLHKVRHSQARPFECEVCKKEFARKKNLDIHVRIHTDDRRCVCKLCGKKFIQTASLKLHLRVHHANK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-