Basic Information

Gene Symbol
ZFY
Assembly
GCA_946894085.1
Location
CAMPPJ020000191.1:361552-373968[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 5.2 4.3e+02 2.6 1.0 1 20 187 206 187 209 0.90
2 22 0.025 2 9.9 1.1 1 20 216 235 216 238 0.91
3 22 0.0019 0.16 13.4 0.6 2 23 271 293 270 293 0.91
4 22 0.0008 0.065 14.6 4.4 1 23 299 321 299 321 0.97
5 22 0.051 4.2 8.9 3.4 1 20 327 346 327 348 0.93
6 22 0.0008 0.065 14.6 4.4 1 23 359 381 359 381 0.97
7 22 0.01 0.83 11.1 4.5 1 23 387 409 387 409 0.98
8 22 0.092 7.5 8.1 0.8 3 22 420 439 419 443 0.90
9 22 0.04 3.3 9.3 0.0 1 23 451 474 451 474 0.95
10 22 0.00088 0.071 14.5 0.2 1 23 480 503 480 503 0.95
11 22 2.3 1.8e+02 3.8 0.0 1 11 512 522 512 526 0.85
12 22 0.00088 0.071 14.5 0.2 1 23 556 579 556 579 0.95
13 22 2.3 1.8e+02 3.8 0.0 1 11 588 598 588 602 0.85
14 22 0.00027 0.022 16.1 0.2 1 23 632 655 632 655 0.96
15 22 0.64 52 5.5 0.0 1 11 664 674 664 678 0.86
16 22 0.00088 0.071 14.5 0.2 1 23 708 731 708 731 0.95
17 22 1.1 86 4.8 0.3 1 14 740 753 740 756 0.84
18 22 0.00088 0.071 14.5 0.2 1 23 784 807 784 807 0.95
19 22 1.7 1.4e+02 4.2 0.3 1 14 816 829 816 832 0.84
20 22 0.00088 0.071 14.5 0.2 1 23 860 883 860 883 0.95
21 22 4.7e-06 0.00038 21.6 0.3 1 23 892 914 892 914 0.97
22 22 0.00018 0.015 16.7 0.4 1 23 920 943 920 943 0.97

Sequence Information

Coding Sequence
ATGGAGGGCTCGGAATCACTAACGACGTGTAGGTTTTGCCTGGCAACGGAAACAGCAGCACGTCTCACTCGTCGCGACCTCACGGCCTTCTACCTCGCATTCCGCGGCTACGGACTCGGCCTCCAACACATCAGCAAAGAGAAGCTCGCAACAGTCTGCAGATCGTACATCAATGCGCCCGTCGCTCTCTCCACCTGCCCGTGTCCCGACGCCACGTTTTCCCTCTGCTCGGCCGCACGATTGCGTCCCCGAAGGTCTAGACGCCTCACTTCGGCGGAGAAGTCAGATTCGGAGGTGGAGGCGTCTGCGGAGAACCTGGTCGACGAAGCTGCAGCACCGGTGGAACCGCAAAAGAACTGTGAAGTGAAGACAGAGAAAGTAGAAAAGCCGGTGGCATCACAGAAAAAGGACCCCAGCCAGCCCAAGGCACGCAAGGACCCCGACGAGCTGGTGGCGCGCTGGCGGCGACTCGAGGTGGAGGTGGTGAAGCTGAGCGTGGAGCAGCAGCGTCAGGAGCTGGAGGTCCGGCGGCGCTCCGCCCGCTACCAGCAGTGGCGGCACAAGTGCGAGCGCTGCGCGGTCGGCTTCCACGAGGAGGTGTCGCTGAGGCGGCACAACGTTGCGCACGACGAGTCACGAGGGCCGTACGAATGCCAGATCTGCTACGTGCGGTTCGCGAAGCAGCACCAGCTCTCCAGCCACAGCGGCGGACACAAGCGGCGCTGGCGCTGCCTCCGCTGCGGCGACACCATCCTCAAGAACGACTACCTGGAGGCGCACCGCGCCAAGTGCACCGGCAGCCCGCCTCTCCGCTGCGACACCTGCGGCAAGTACTTCTCcaacaaactGCGGCTGAGGCAGCACGTGTCGGCGGCGCACAACTCGAGGCGGAAGCACGTGTGCGACGTGTGCGGGCGCGGCTTCAAGGCGAAGCACCACATCCGCTACCACATGCGCATCCACACCGGCGAGATGCCCTACCAGTGCCATGTCTGCGGCAAGAAGTCCTCCACCTCCACCAGCCATCGCATACACATGACGCACGTGTCGGCGGCGCACAACTCGAGGCGGAAGCACGTGTGCGACGTGTGCGGGCGCGGCTTCAAGGCGAAGCACCACATCCGCTACCACATGCGCATCCACACCGGCGAGATGCCCTACCAGTGCCACGTCTGCGGCAAGAAGTCCTCCACCTCCACCAGCCATCGCATACACATGACTGTGCACAACAAAAAGACGAAGAACCCCGAGGCGTACTGCGTGGAGTGTGACAAGTACTTCAAGAATAAGAATATCCTGCAGATTCACTACCAGCGCTCGCTCAAACACAACAGCAAGGACTCGTTCCCTCACGCGTGCTCCGAGTGCCCGGAGCGGTACCCGGCGGCGGCGGCGCTGCGCATCCACGTGAACAGTGTCCACCTCAAGTCGCGCGCATTCCGCTGCGGGCTGTGCGACAAGGCGTACTATTCGCGCGGCACGCTCGCCGTGCACGTCAAGGAGAAGCACGTCCGCGGCGAGAGGACGCGCGACCACCCGTGCCCCGTGTGCGAGAGGGCGTTCATTGTGAGTGGACTCGCTTGTAATGTAGGAAGTGGCGCCTCAAGCGGTACCCGGTGGCGGAGGCGCATCCACGTGAACAGTGTCCACCTCAAGTCGCGCGCGTTCCGCTGCGGGCTGTGCGACAAGGCGTACTACTCGCGCGGCACGCTCGCCGTGCACGTCAAGGAGAAGCACGTCCGCGGCGAGAGGACGCGCAACCACCCGTGCCCCGTGTGCGAGAGGGCGTTCATTGTGAGTGGACTCGCTTGTAATGTAGGAAGTGGCGCCTCAAGCGGTACCCGGTGGCGGCGGCGCATCCACGTGAACAGTGTCCACCTCAAGTCGCGCGCGTTCCGCTGCGGGCTGTGCGACAAGGCGTACTACTCGCGCGGCACGCTCGCCGTGCACATCAAGGAGAAGCACGTCCGCGGCGAGAGGATGCGCGACCACCCGTGCCCTGTGTGCGATAGGGCGTTCATTGTGAGTGGACTCGCTTGTAATGTAGGAAGTGGCGCCTCAAGCGGTACCCGGTGGCGGCGTCGCATCCACGTGAACAGTGTCCACCTCAAGTCGCGCGCGTTCCGCTGCGGGCTGTGCGACAAGGCGTACTACTCGCGCGGCACGCTCGCCGTGCACGTCAAGGAGAAGCACGCCCGCGGCGAGAGGACGCGCGACCACCCGTGCCCCGTGTGCGAGAGGGTGTTCATTGTGAGTGGGCACGCTTGTAATGTAGGAAGTGGCGCCTCAAGCGGTACCCGGTGGCGGCGGCGCATCCACGTGAACAGTGTCCACCTCAAGTCGCGCGCGTTCCGCTGCGGGCTGTGCGACAAGGCGTACTACTCGCGCGGCACGCTCGCCGTGCACGTCAAGGAGAAGCACGTCCGCAGCGAGAGGACGCGCGACCACCCGTGCCCCGTGTGCGAGAGGGCGTTCATTGTGAGTGGGCACGCTTGTAATGTAGGAAGTGGCGCCTCAAGCGGTACCCGGTGGCGGCGGCGCATCCACGTGAACAGTGTCCACCTCAAGTCGCGCGCGTTCCGCTGCGGGCTGTGCGACAAGGCTTACTACTCGCGCGGCACGCTCGCCGTGCACGTCAAGGAGAAGCACGTCCGCGGCGAGAGGACGCGCGACCACCCGTGCCCCGTGTGCGAGAGGGCGTTCATTACGAGCAGCCAGCTGAAGGCGCACTCGCGCATCCACACGAAGGAGCGGCCGTACGCGTGCCCGCTCTGCCCCGCCACCTTCACCTTCAACTCGGGACTCTACACGCACACGCGCAGCCGCCACAAGCTGAGCACGGCCGAGCTGCGAGCGCGCCTCGGGCTCGCCGCGCTCGGTAAGGCCCGCATCTGA
Protein Sequence
MEGSESLTTCRFCLATETAARLTRRDLTAFYLAFRGYGLGLQHISKEKLATVCRSYINAPVALSTCPCPDATFSLCSAARLRPRRSRRLTSAEKSDSEVEASAENLVDEAAAPVEPQKNCEVKTEKVEKPVASQKKDPSQPKARKDPDELVARWRRLEVEVVKLSVEQQRQELEVRRRSARYQQWRHKCERCAVGFHEEVSLRRHNVAHDESRGPYECQICYVRFAKQHQLSSHSGGHKRRWRCLRCGDTILKNDYLEAHRAKCTGSPPLRCDTCGKYFSNKLRLRQHVSAAHNSRRKHVCDVCGRGFKAKHHIRYHMRIHTGEMPYQCHVCGKKSSTSTSHRIHMTHVSAAHNSRRKHVCDVCGRGFKAKHHIRYHMRIHTGEMPYQCHVCGKKSSTSTSHRIHMTVHNKKTKNPEAYCVECDKYFKNKNILQIHYQRSLKHNSKDSFPHACSECPERYPAAAALRIHVNSVHLKSRAFRCGLCDKAYYSRGTLAVHVKEKHVRGERTRDHPCPVCERAFIVSGLACNVGSGASSGTRWRRRIHVNSVHLKSRAFRCGLCDKAYYSRGTLAVHVKEKHVRGERTRNHPCPVCERAFIVSGLACNVGSGASSGTRWRRRIHVNSVHLKSRAFRCGLCDKAYYSRGTLAVHIKEKHVRGERMRDHPCPVCDRAFIVSGLACNVGSGASSGTRWRRRIHVNSVHLKSRAFRCGLCDKAYYSRGTLAVHVKEKHARGERTRDHPCPVCERVFIVSGHACNVGSGASSGTRWRRRIHVNSVHLKSRAFRCGLCDKAYYSRGTLAVHVKEKHVRSERTRDHPCPVCERAFIVSGHACNVGSGASSGTRWRRRIHVNSVHLKSRAFRCGLCDKAYYSRGTLAVHVKEKHVRGERTRDHPCPVCERAFITSSQLKAHSRIHTKERPYACPLCPATFTFNSGLYTHTRSRHKLSTAELRARLGLAALGKARI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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