Ilum006356.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ignelater luminosus
Gene Symbol
TIGD4
Assembly
GCA_011009095.1
Location
Ilumi1.2:55112-61876[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.0039 0.38 11.9 2.5 1 23 386 409 386 409 0.96
2 20 0.031 3 9.1 0.9 2 23 415 436 414 436 0.96
3 20 0.037 3.7 8.8 10.1 1 23 442 465 442 465 0.94
4 20 3e-05 0.0029 18.6 0.3 1 23 471 493 471 493 0.97
5 20 1.5e-05 0.0015 19.5 1.9 1 23 498 520 498 520 0.99
6 20 0.00039 0.038 15.0 0.4 1 23 529 551 529 551 0.98
7 20 0.00036 0.035 15.2 0.7 1 23 557 579 557 579 0.95
8 20 9.1e-07 8.9e-05 23.3 0.7 1 23 585 607 585 607 0.98
9 20 8.8e-06 0.00086 20.2 2.3 1 23 613 635 613 635 0.98
10 20 0.00046 0.045 14.8 2.4 1 22 641 662 641 662 0.93
11 20 0.23 22 6.3 0.8 1 22 839 860 839 862 0.85
12 20 0.0058 0.56 11.4 0.1 2 23 868 889 867 889 0.94
13 20 0.023 2.2 9.5 5.9 1 23 895 918 895 918 0.93
14 20 0.11 11 7.3 1.5 1 23 924 946 924 946 0.90
15 20 3.4e-06 0.00033 21.5 2.2 1 23 951 973 951 973 0.99
16 20 2.7e-05 0.0026 18.7 0.4 1 23 982 1004 982 1004 0.98
17 20 0.00038 0.037 15.1 0.4 1 23 1010 1032 1010 1032 0.97
18 20 1.1e-06 0.0001 23.1 0.3 1 23 1038 1060 1038 1060 0.98
19 20 1.2e-05 0.0012 19.8 1.7 1 23 1066 1088 1066 1088 0.98
20 20 0.00012 0.012 16.6 3.2 1 23 1094 1116 1094 1116 0.97

Sequence Information

Coding Sequence
ATGGAACCAATAATGAAGGAAGCATCAATATCAAAGAGAAGAATGCTTTCAATAGAAGAAAAAGGAACAATTATTAAAAAATTAGAATCAGGCGAATCGAATGCCAATTTAGCCATCAAATATGATTTGTCAGCATCGACCATATCAACTATATGGAAAAACCGCGACAAAATAAAACGAGCTATTGATAATAACTTATTAAAGCAGAAGAAAGTACGATTATCTAGTCATAGAGATGTTGAAGAAGCCTTGCTAGAATGGTTTAAAGATCGAAAAAGATTAGGTATACCTGTAAATGGGCCTGTATTATTAGCCAAAGCAAACGATTTTGCAAGAAGTATGGGTAAAGTGAATTATAGATGTACAAAGAGTTGGATTGGCAGATTGGTGCAAACCTTTCCGAAGACCCAGATGCTAATACTTCCTCAGCAAATCAGTGGGCATAATCTTATTTTGAATAATCAACCAAAACAAACTGTAAAGTGTCAACCACGAGTAGCTTTTATTTGCCAACCACAAAATATTCTAGTTGCCCAAATTCAAAGTGTTCCCACTAACCAACTACAGACTGGTCATTTACAACGTGCTACAATTCCGATGTTGCAATATCAAGGGCAAAATGTGGCCAACCAACAGCAAAATACTCTGTCTTGCCATAAACCACAATATCAATTACAAAATAGCACAGTCAATCAACAAAATGTTTTGGCTTACCATAAACCACAATATCAGTTACAAAACAGCATAATCAATCAGCAAAATGTTTTGACTTATCATAAACCACAATATCAATTTCAAAACAACCTGACCAATCAGCAGCAAAATGTTCTGGTTTGCCAACCACAATATCAAGTGCAAAACATTGTATCTAATCAACAACAAAATATTGGGACTTATTCATTTACTCAATTTAATCAGAAGCAAAAGTCCATGGCAAATCAACAAGATCTCTTAGTTTATCAATCACAACAGATTCCAATTAATAGACTACAATATAACGATAATAACCAACTACCAAATGTTACAACTCATCAATCATACGTTTCAGTTTCTAACCAAAAGCAAAAAATTGATAGTAAATCACAACCTATTGCGACTACTCAGTCACAAGATGTCTTAAATGCTGCCATTTCTCAACCAAATAATATAAGATATTACTACTGTACACGATGTCCTGAGAAATTTACAAGTAAATATCAACAAAAACAGCATGGTAATAAAGTTCACTTGTCTAAAAAAATTTCTTGTCCAACATGTGAACGAATGTTCAAATGGAAATTTCAGATGCTGAAGCATCAAGAGAGTCACAGCGCTGAAAGAAACCACAAATGTGAAATTTGCCATAAACGGTTTAAAACTAAACACTCGTACAGTTTGCACTTTAGTAAGACTCACAGCAATGAATTTAAATTCAATTGTGAACAATGTGGGAAAGGATTTATTTACGGGTCTCAACTTAAAGCACATACTAAAGTACATTCGGATACACTTTATAAGTGTGACGATTGTAATAAAATATTCAGAGATGAGAAATACTATAAGATGCATTTAAAGATTCACAAACCAGGTTATACAGCTCAAACATTTACATGTGTGAAGTGTGGTGCAAAGTTATCTTCATCCGGAGGCTATAGAAAGCATATGCGTGCTCATAATACAGATCTAAAATACATTTGTGATACCTGTGGAAAGCATGTGACAAGCTTGAGTAGTCTAAGAGCACATTCATTATTACACTCTGGAGAAAAGCCATTTGTATGTGAATTTTGCGGTAAAAGTTTTAACAAACCAGGTTTGCTGAAGACCCATAGACGTGTACATACTAAAGAAAAACCATATGTGTGTAAGTTGTGTCAGCAACGTTTTACACAACGATCTAGTCTTCGAATTCATGAAAGAAAACATACTGGAGAAAAGCCATATTGTTGTGATATATGTCAAAAGAGATTTGTTACAAAGACATTGCTGAAGATTCATTCGAAAACCCAGATGCTAATACTTCCTCAGCAACTTACTCTGGATAATCAACCAAACCAAGATGCAAAATATCAACCACGAATGGCTTTTATTTGCCAACCACAAAACATTCTAGTTGCTGAAATCCAAGGTGTTACAACTAACCAACTGCAGAATTATCCACAAGCTATAATTTCGAGCACAATCAAACAACAACAAGATTTTTTGGTTTGCCAACCACAATATCAAGTGCAAAGTATTACAGCTAATCAGCAACAAAATCTTACCTATAATTCACCAATTCAATTTAATCAACATCAATATCAGGAGCAGAAGTTTATGGTTAACCAACACGATTTCTCGGGTTATCAATCACAACAGGTTTCAATTAACAGGCCACAATATAACCAACAATCAAATGTTTCAATTCATCAGTCATATGTTTCAGTTCCTGAACAAAAGCTAGAAACTGATAGTAAACCACAACATATTGTGACTAATCAGTCGCAAGATATCTTAAGACATCCTGTGGTTTCTCAGCCAGATAATATAAAATATTACTACTGTACACGATGTCCTGAGAAATTCACAAGTGTAGCAAAGCAAAAACAGCACGGTGTCAAAGTTCATTCACATAAAAAGGTCCCTTGTCCAATATGTGGACGAATGTTTAAATGGAGATTCCAAATGCTGAAACATCAAGAGGGTCATGATATAGAAAAAAACCACAAATGTGAAGTTTGCCATAAACTGTTTAAAACTAAACACACCTACAACTTGCATGTTGCTAACATTCACAGGAATGAATTTAACTTCAAATGTGAACAATGTGGGAAAGGATTTCTTTATGAGTCGCAGCATAAAGCACATGCCAAAGTGCATTCAGGTACACTTTATAAGTGTGATGATTGTAATAAAGTATTCAGAGATGAGAAATACTATAAGACACATTTAAAGATTCACAAACCAGACTATACAGCTCAAACATTCACATGTCCGAAGTGCAATGCAAAGTTTGCTTCATCTGGAGGTTATAGAAGCCATATGCGTGCTCATAATACAGACCTAAAATACATTTGTGATACCTGTGGAAAGCACGTGACAAGTTTAGGTAGTTTAAGAGAGCATTTATTATTACATTCTGGAGAAAAACCATTTATATGTGAATTTTGTGGTAAAAGTTTTAACAAACCAGCTTTGTTGAAGGCGCATAGGCGTGTACATACTAAGGAAAAACCATATGTGTGTAAGTTGTGTCAGCAGCGTTTCACACAACTGTCCAGTCTTCGAGTTCATGAAAGAAAACATACAGGAGAAAAGCCATATTGTTGTGATATATGTCAAAAGAGATTTGTTACAAAGACATTGCTGAAGATTCATTCGAAAGTGCATGGCACCATGCTTGCTGATATAAATAAAGGGAAAGAACAGAAAAGTTAA
Protein Sequence
MEPIMKEASISKRRMLSIEEKGTIIKKLESGESNANLAIKYDLSASTISTIWKNRDKIKRAIDNNLLKQKKVRLSSHRDVEEALLEWFKDRKRLGIPVNGPVLLAKANDFARSMGKVNYRCTKSWIGRLVQTFPKTQMLILPQQISGHNLILNNQPKQTVKCQPRVAFICQPQNILVAQIQSVPTNQLQTGHLQRATIPMLQYQGQNVANQQQNTLSCHKPQYQLQNSTVNQQNVLAYHKPQYQLQNSIINQQNVLTYHKPQYQFQNNLTNQQQNVLVCQPQYQVQNIVSNQQQNIGTYSFTQFNQKQKSMANQQDLLVYQSQQIPINRLQYNDNNQLPNVTTHQSYVSVSNQKQKIDSKSQPIATTQSQDVLNAAISQPNNIRYYYCTRCPEKFTSKYQQKQHGNKVHLSKKISCPTCERMFKWKFQMLKHQESHSAERNHKCEICHKRFKTKHSYSLHFSKTHSNEFKFNCEQCGKGFIYGSQLKAHTKVHSDTLYKCDDCNKIFRDEKYYKMHLKIHKPGYTAQTFTCVKCGAKLSSSGGYRKHMRAHNTDLKYICDTCGKHVTSLSSLRAHSLLHSGEKPFVCEFCGKSFNKPGLLKTHRRVHTKEKPYVCKLCQQRFTQRSSLRIHERKHTGEKPYCCDICQKRFVTKTLLKIHSKTQMLILPQQLTLDNQPNQDAKYQPRMAFICQPQNILVAEIQGVTTNQLQNYPQAIISSTIKQQQDFLVCQPQYQVQSITANQQQNLTYNSPIQFNQHQYQEQKFMVNQHDFSGYQSQQVSINRPQYNQQSNVSIHQSYVSVPEQKLETDSKPQHIVTNQSQDILRHPVVSQPDNIKYYYCTRCPEKFTSVAKQKQHGVKVHSHKKVPCPICGRMFKWRFQMLKHQEGHDIEKNHKCEVCHKLFKTKHTYNLHVANIHRNEFNFKCEQCGKGFLYESQHKAHAKVHSGTLYKCDDCNKVFRDEKYYKTHLKIHKPDYTAQTFTCPKCNAKFASSGGYRSHMRAHNTDLKYICDTCGKHVTSLGSLREHLLLHSGEKPFICEFCGKSFNKPALLKAHRRVHTKEKPYVCKLCQQRFTQLSSLRVHERKHTGEKPYCCDICQKRFVTKTLLKIHSKVHGTMLADINKGKEQKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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