Basic Information

Gene Symbol
-
Assembly
GCA_907269075.1
Location
OU026096.1:13640875-13647629[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00085 0.067 14.3 0.5 1 23 311 334 311 334 0.92
2 12 1.6 1.2e+02 4.0 0.7 1 8 347 354 347 356 0.92
3 12 1.5e-05 0.0011 19.8 2.4 2 23 408 429 407 429 0.96
4 12 0.019 1.5 10.1 1.1 3 23 435 456 433 456 0.92
5 12 0.34 27 6.1 1.0 1 23 459 483 459 483 0.95
6 12 0.0032 0.25 12.5 1.0 5 23 563 581 561 581 0.94
7 12 1.4 1.1e+02 4.2 0.6 2 23 601 623 600 623 0.92
8 12 1.1e-06 8.4e-05 23.4 4.1 1 23 629 651 629 651 0.98
9 12 0.0029 0.23 12.6 4.3 1 23 656 678 656 678 0.97
10 12 0.019 1.5 10.0 5.8 2 23 685 707 684 708 0.95
11 12 5.6 4.4e+02 2.3 0.5 1 19 715 733 715 734 0.81
12 12 0.024 1.9 9.7 2.0 3 19 747 763 746 768 0.94

Sequence Information

Coding Sequence
ATGGAGAGAGAAGACGTTACTCCCGAGTTGGGGATGGTCTATCCTATCGTATTCCTACCGAAAAGGAGCACTAACTTGGAAACGAGCGCCAATATCAGCGACAACATCTATATTAACATGAACATGACGACTATAGACGCTGAAGGTAACGAAATGTGTATTTACTCAGGGTTCTGCTGCATTAAAATGGTAGATTCCTGTGATACTAATATTCCAACTGAACCAACTCCGGAAACTAGCGTATCACTCGATGATGACATAGAAAATATGCCAATTATCTTATCTGAGGCAAACCAGCTTTCCTTCCCTGCTTTCAATCAATCCAGGGTCTGGATTGACCCATCCAGAAGTCCCTATGTTTATAATAATTACGATGTAAGCGCTCAGGAGCACTACTCCATTCACGAAGCTCAGGGCTGCATCACCGTGGAACAACACAACACATACATCACTCAGAATGTATATAACTATAAAGAAACAAACATTTGCAACGTCCAAGAGTTGCCGAAAGACTTTGGGCAACATAAAAAATATAGGAAATTAGAAGCGACTGCAGGACAGTCCGATTCTAACAAAAGTTATTACGAAGATGATGAATTTGAATGTGGAGTATTTCTTTCTAATTTACCCGAAGAAATCATCAATGAGAAAAAATCCAAAGATAAAAAACCTACAATTTCTTCCGGACCTAAAATAGAAGATAAAAGTGCACTCCGCCAGTTGTTGTCACAGGACATTGAACCTGTTTCCAAACAGAGAAAGACTATTTTATATCTGGGTGAGGATTCATACTCGGGGCAAACAATACAGAATATATCATACAATGATCCGATGATGACATGTGCAGGGGTTGATCAAGACTATGCCGGGGATGTTCAAGTGGACCATGAAGTTGTTATTGATTCAACAGCAGACCCTAAAAAGAAGCGTTACCAATGTGACAAGTGTAAACAGATATTCAACGACATAGCGTCGTTCAGACAGCACATGGTCGGCAATCACAACCACAGCAGCCAACCGCAGACCACCAACATGCCTTACAAGTGTACTGACTGCGGACGATTCTGGACACCTCCGGGTGCTCGGCGACGTCGAGGTCGGCCACGAAAGCGCTGGCGAGACGACCTCCACCGCCTCGAGCCAGCTTGGCCGGAGGTGGCCCAGGACCGCGAACGATGGAGGGAGATGGGGGATACTAGGGGCCACGGCGATCCGGAGCTAGAATGCGATAAATGCCACAAAGTGTTCGCATCAAAGTTCACACTGCGAGCCCACCAGAAGTTGCACAATAGGAAGCATCTGTGCCATGTCTGTGCAAAATCTTTCGTTACCGGTGAAGGATTGAGGCAACACGCAGCCAGATCCCATTCGATGTTCATGTGCGATTCAAAGAAGTGTAACTTCGTCGCTGGAGTGTACTCCGACTTGTGTGACCACCAGAGGGTACATAGGGAACTTAGTGATGACGACAACGATTCCAATTTAGAGGTCGAAATGAAATCCGAAGAGAACACTAAGACCGAGCTCGTGATAGAAAGTGACAAGATCATAGAACCCGTGACAGAAGGTGACAAGATCACAGAACCCGTGACAGAAGGTGACAAGATAAGACAGGCGGATATTGTGATAGCCAAAGTGATGTCCAATAAGGTGTTCCTTTTGAACGCTAAGAAGGCTAACAAGCAGAAGTGTCATAAGACATTCGACCGTATCGGCGACCTGAAACGTCACCTAATAGAACACGTGATCAAGAGCACGATGGCCAAGACACCGATCAACGAAGACGGAACATTGGACATCCAATGCGAGGTATGTCGCTCACAATACTTCACTAAAGTTGACAAATACAAAGCACATCTACGTGAACACGCCAAACTAACGCTATACAAATGCACTTTCTGCGACAAATCCTTTAGCGATTCCAGTAATTTCTCTAAACATAAAAAAATCCACGGCACTGCTTATTTCCAATGCGATTTGTGCCATAGGAAGTTTAATTCGAAGAAAATGATCTCTCAACATATGGAATATCATACTAAAAATAAGCCTATTAAATGTAGGTATTGTACCAGAATATTTCATTTTCAATCGATGTTGAATAAACATGTTAAGAATTCCCATCACGAGAGTCCGGTATCGAAATTTCGCTGTACTTTTTGCGATGATATCTTTAAGTCTCTAAGAGATAAATGGGATCACGAATGGGATGTCCATAATGTTAGGAAGTTGGTTGTTGATTGTTTGATCTGTGGGAGTAAGTTCAGAAAGTATTCGCAATTGAAAAGGCATTGCATTGACGAACATAATTTGGATATACCACCTGCTAGGAAGTTGTTAACGAAACGGTTTAATAATTATAATTCTTAG
Protein Sequence
MEREDVTPELGMVYPIVFLPKRSTNLETSANISDNIYINMNMTTIDAEGNEMCIYSGFCCIKMVDSCDTNIPTEPTPETSVSLDDDIENMPIILSEANQLSFPAFNQSRVWIDPSRSPYVYNNYDVSAQEHYSIHEAQGCITVEQHNTYITQNVYNYKETNICNVQELPKDFGQHKKYRKLEATAGQSDSNKSYYEDDEFECGVFLSNLPEEIINEKKSKDKKPTISSGPKIEDKSALRQLLSQDIEPVSKQRKTILYLGEDSYSGQTIQNISYNDPMMTCAGVDQDYAGDVQVDHEVVIDSTADPKKKRYQCDKCKQIFNDIASFRQHMVGNHNHSSQPQTTNMPYKCTDCGRFWTPPGARRRRGRPRKRWRDDLHRLEPAWPEVAQDRERWREMGDTRGHGDPELECDKCHKVFASKFTLRAHQKLHNRKHLCHVCAKSFVTGEGLRQHAARSHSMFMCDSKKCNFVAGVYSDLCDHQRVHRELSDDDNDSNLEVEMKSEENTKTELVIESDKIIEPVTEGDKITEPVTEGDKIRQADIVIAKVMSNKVFLLNAKKANKQKCHKTFDRIGDLKRHLIEHVIKSTMAKTPINEDGTLDIQCEVCRSQYFTKVDKYKAHLREHAKLTLYKCTFCDKSFSDSSNFSKHKKIHGTAYFQCDLCHRKFNSKKMISQHMEYHTKNKPIKCRYCTRIFHFQSMLNKHVKNSHHESPVSKFRCTFCDDIFKSLRDKWDHEWDVHNVRKLVVDCLICGSKFRKYSQLKRHCIDEHNLDIPPARKLLTKRFNNYNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00837904;
90% Identity
-
80% Identity
-