Basic Information

Gene Symbol
-
Assembly
GCA_907269075.1
Location
OU026109.1:1884290-1903806[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00045 0.035 15.2 3.8 1 23 1620 1643 1620 1643 0.95
2 15 0.023 1.8 9.8 5.1 1 23 1652 1675 1652 1675 0.97
3 15 0.069 5.4 8.3 0.4 2 23 1688 1710 1688 1710 0.97
4 15 0.016 1.3 10.3 2.1 1 23 1719 1742 1719 1742 0.96
5 15 0.00038 0.03 15.4 2.5 1 23 1754 1777 1754 1777 0.96
6 15 0.0018 0.14 13.2 0.5 2 23 1801 1823 1800 1823 0.96
7 15 0.00053 0.042 14.9 1.8 2 23 1833 1855 1832 1855 0.96
8 15 1.4 1.1e+02 4.1 3.3 3 20 1861 1878 1860 1880 0.92
9 15 0.0039 0.31 12.2 1.5 2 21 1885 1904 1884 1907 0.94
10 15 0.0003 0.024 15.7 1.3 3 23 1917 1938 1916 1938 0.96
11 15 0.00098 0.077 14.1 4.5 1 23 1943 1966 1943 1966 0.96
12 15 0.00013 0.01 16.8 0.1 1 23 1978 2001 1978 2001 0.97
13 15 1.5 1.2e+02 4.0 0.6 1 20 2020 2039 2020 2043 0.90
14 15 1.1 85 4.5 0.2 12 23 2059 2070 2049 2070 0.76
15 15 0.027 2.1 9.6 2.0 2 23 2076 2097 2075 2097 0.97

Sequence Information

Coding Sequence
ATGGCAGAAGAAGATAATTCGAGAACTATCAAGATATTTACCAGAAGAGCATTGTATGAGATCTTGAAGGAATTCAAGGGCCACAAAATGGAAGAAAAGTTTTCATTGTTTGAAGATAGACTTGTGCAATTGACAAATTGTCCGGAACATGAGAAACAAAGAATTGTAAATGGTTTGAAGCACTTTAAAAGCGAATTCAAAAAGAAGTGGAGAGGAGCTTCATACAAAGAAGAACGGTTTTTAAAAAGTAATGAAGTGTGGCTTACATCTTCGATGGAATTACCTAACTGGCCTGAAATTACCTTACCAAAACCTGGACGTCCAAAAAAATCATTTGAAGATGTGTGTGACCGTAGCAAACGGAGAAAAACAAAAGATCTGCGTGAACAAGTATCTGTCGAGGAGTTGACTTATGCTGCTGGCGTGAGTCAGGGCACTTCAGGAAACAAAGATGCATCAAAAATAATTAAAGAATTAATGGCTTCACCCACCAGAGCTACTAAACTTAGAAAAGTTATCTCTACTAGCAAGAAACAAACAACTGTAAAAAAATATACGCCAGCAGAAGCACTGGCTATCTTTGTTGAAGGTGATTTCACTAGAAGACAATGGGAAATAATCAACAGATCTGGTAAAGCTATTTACCCCTGCTATTCTGTCATACAAATGGCTAAGATTGAATGTTATCCCGAGGAAGAATCAATACATGTCACTGAGACAAGCGCAGAAGTTAAACTTCAAGCATTACTAAATCACACTGCATTGCGCTTGTACAAATATATAGCGGAGGTTGTCAATACAACTGAGTCGAGTATCACTCCTCCTCCCAAGAAGATCGAGCAGTGCCTAGCAACCGCTAGAAGAGCTATTGCAGCTGGAAGAAACGAGCAGTACCTAGCAACCGCTAGAAGAGCTATTGCAGCTGCAAGATACGAGCAGTCCCTAGCAACCGCTAGAAGAGCTATTGCAGCTACTCCATGCTCTTTAGCATCCTCTCACTGCGGCCAGGAAACCCTTAGCCGTCAGTCGATTGGTCTTGAAAAGGAAGCAACGAAACAAAACACTATGGAAAATATGGACATTGAAGAAATCAATCGTATTATCAGAAGCCAAGAGGCGGACTACAACGAAATCAAACGAATACTTACAAATCTTAAAAAAGACCCAAATACAAGAAAAACCGACAAGTACATTAACGAACGGAGGGCTCGACTCACAGAAATACTCAACAGAACTACTACCAATCACGAGTTACTTAGAAATCAACAAGTACTAGTTGATCATAAGTACATTACTACAAGTTACTACGAATCCATCAAGTCACTCGTCAATCAAACTATGGAAAACTTAGCAAAATGCGAGAAGCGACTACAGTTGCTAGGCAAACTATACGAACCACAAGACATCGAAGAAAATGAATGTGAAGATGCGAACTCACCTAAAATCTTCATTCAACTCTATCGTATCACACAAATGCAGAAGAAACTACAAACAGCTACACAAGCGTTAACAGAAGATAAACCTGTATGGTACTGGGAATCACTGGCGAAAAATATAGAGAAGCAATGGCAAGACATAGAGGAAACTCACCTACTCATTCTAATGGAAGACAGCACCTTAGACCACAGCTACTTTCGAGATAACTTGTTTGAAAAAACGCAAACAGATTACGATGTAATCATTGAGCGTATTACGGCTAAAGCAAGTAACACAAAAAGAGTGGGGAACAGTGAGCACAAAAGTAACCTGCCAAGAATAATTATTCCAGTTTTCGACGGCAACTATGAGTCATGGGATTCATTCTACGACTTGTTTCTAAAAATCATACATGAAGATAAGTCATTATCAGCGACAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGCGAAGCACGTAGATAACATTCTCAATATAGCAAAGATAAATCACGCCACTGCAGCCAACTTAAAAAGTCTACATGATACGATAAACCAAAACATAGAAGCACTTCGACGTCAAAACATAGACACAACTACATGGGACCCCATCCTGGGGAGAATTCTCAGTAGAGTGTGGGACTCTGAAACAAACGAAAAGTATGAACAACAATTAACCGAACCTAAAAAGCCACAAAAGATTGATGAGATGATGGAATTCCTGGAGAAACGATTCCAATGCTTACAGACAACAACTACGATAAGCAAACAAACAAAAACAAATTACAAGACAAGATACGACACACCAGGCCCATACAAGAGGTCAGACAACAATCATTGTTGGTATTGTAACAAAAAACCATACCATACCATATACCAATGCATACAATTTAAACAACTATCAGTAGAAGAACGATACAAGGCAGTTAAAGAGAAAGGAATATGCAGGAATTGCTTGGCGCACAGCCAATCAGAAGAATGTATGAGTACAAAGACTTGCCAACACTGTGGAAGGTTAGGACACCATTCCTACCTACACCAAGAAAACCATAAGCCAACTAGATATACGAAGAACGAAAAAACCAATACATCTAAGAATACAACTACAACTAGGACAAACAATATGCATACAAATACGACAACGACACTACCAAAAACTACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGCACGGAAACAGTAGCTCAACTACTAGCTTACCCGAGGAACAGAACACACGTTGAAGTAACGGGGATAGCTGACGAAAAACCCAAAATAGCGAATTACTCCATTGAAGTGAAATTACAACCAAGATTTCCGAGTGAATTCAAGCTAATAACTACACTAATAATACTTCCAAAACTAACTGGTGCCATACCGAGTACCAATATACCACAATTAGAGGAAAGGCAGTTAGAAAACAAAATGATAGCCGATCCAACTTACAATAAAAGAGGCCCAATCGACGTAATATTGGGAGCTCAAGACTATAGCAAACTACTACTACAAGGGCTATACAAGATTAATGACGACATAATAGCCCAAGACACACATTTTGGATGGATTCTATCCGGGTTCGTCAGTAGCCACACTACAGATAGAATGAAAATCGGGACTGCATGCATTGACAGAGGAGTCTTTAGAATAGAGACAAACTTCGAAAAAGAACAGATTGAACAAAACCTTAGACAAATAAAGAAAGCAGTGACACAGTTCGACGACCTTTGTGAAATAGCAAAAAATACAACCAAAAATGCGACACATTGTGAACAATTCCACCACTACTTAAAAGAATCCGAGTCAAAGTACGAAAGAACAAAAGAATACCTAATGGAAGCAAACCAAACCAAAAGAAAGAAGAGAGGTATATTAGGACAGATATTAACATCAGTTTTTGGCGTAAATGACGAGGTCTACAGGGACATAGATAGCCTGAACAAAAACCAACAACAACTAATCGAAGCTGCAAATCAACAAACGAAGTTTATGATATCAACGGTATCACAAGTTAATGAGACAGAAAATAGAATCACGAAAAAACTACAAAAATTTCAAACAAAACTAAACCAGGTCATACAATTTATACATGAAACAGATTATTGGTACCAAGCAGTCATCAGAAACAGTGTAAATATACATATAATAGAAACGTATCAGTTAGCAAATGATTACATAACTGAAATAACAGAACATTACGCTGGATTATTAGATGTATACCTATCGAAATCAAGTGTATACAGCATTTTGACTCCAAAGAACGTCAGTAACCTAATTTATACGGCAAATAACAAACTTCCTAGTAACTTAAAGATAGTACAACGACAACTGCTAGAAACAAAAATGGCGGAAAACGAAACACACATCCAAGTGTACGCCTACTTTCCGATACAGGACACAACAAAATACACAATGATCTATGTCACAGCGGTTCCTGAAAAAACACGGGACCAGCTATTCCAAACCGTCGAAATACAAAAATCATACATTGGCGTAGACTATAACAACGAACAGTATTTTGACTTAGATCATGAAGAATTTACAAGTTGCCTACAAAGTATGAGTACATACGTCTGCTTTCCTAGTGCCGTGAAGAACATGCAATCAAATGATAATTGCATTGTTAACCAGCTCTTCAAAAACCAAACACAAACGAGGTGTCAATCAAAAACGTTCGACATAACTAACAAACTGTTATGGAAACAACTGCATATGCAAAATACATGGTTATTCATAGCTAAAGACCGTAGTTTGACATCGATCATATGTGACGGACAAAGAGAGGAAATTGAACTGCGGGATGTTGGAGTAATACGGATTGCCGACAACTGTATTATAAAGACAACTAATAACATATTAGCTGCAAAAAGAACAATCTCAGTTCAAACCGTAGCGTCATTTTCAAAACCAATCGACTTCTCTATATCCACCTATAATAGCACTGGCACCATATTTAATGTAACCAAAGACGAAGTTATAGAGAGTTCACAAGATATTCTCGACAATGTAGTCAAATCCGAAAATAACTTACAAACTAAACTAGACAATACAATCTGGACCCAATTCCCCCATATAGATGATGAATACCAAGACAGCAATGAGAACAGCCAACCGGAACCCATCGTTAAATTCGACGAACAAAACAAAGAAGCTGTTCTCCTTACATTTGAAAGTGTTATCAACGAAAAGATCCTATACGGAGAACCAATAGAGTCCATAGACCATGATTTTGACAACGAACAAGTTGAACCCGCAGAACTAGCAATGTCTTTTCTTTGCAAGATATGTCATTTGGTGTTTAAAACCCAGAAAACTCTGGTCCAACATCAGAAACGGACTCATAAACGGTTTAGACGAACTTTCAAACATAAATGTGAACATTGTGGCATGCAATATGAATTTAAAAACAGCTTAGAAGCTCATAAGAAGAGAAGGCACTCACCAAACTCGGTCATTGATGATATGATGGAGCGAACTTGTGATATTTGTGCTCTAGTCTTTAAAGGGGTGAATAGACTACGTATGCATATGCGAAGGACTCACGGTTCCTTCGAAGATGCCTTCAAACATGTCTGCCAAGACTGCGGTCTGACGTATGATAAAACTCAAAGTCTACTCGTTCACCGTAAAAGAAAACACCCGACAGTAAAGAAACCAAAAGTAACCCAATGGTTTAACTGTCTGTTCTGCCCTAAAGTCTTCACTCGTAGAGAAACTTACACGAGACATGTACAAAGAAAGCACAAAGTCGACGATGATAACGTCGGCACAAAGGGTAAAATTAAATCTGAAAAGAGTGAAATCGGAGAGACAACTTGTATGTACTGCAGTCTAGTTTTCTCATCGGTCGGTTACTTAAATTGGCATTTAAGAAGGAAGCATAACGTTAAAATCGATGATTACAAGTTAAAATGTAAAATTTGTAACTTATCGTATAATAAAGTTGAAAGTTTAAAACGGCATATTAAGAGGAAACACACACAGGATAATTACTGTAGTGTGTGTTGTAAACAATTTACAAGTAAAAGTAGTTATATTAACCACACACATATAAAACAGGTGCAGGAATGCAATCTTTGTGGGCAGATATTTGCTCACCAAGGTGGGTTAGCCAAACACCTACGTTGCACCCACAAAATTGAAACCCCAGCGACAGTATTCTGTAATATGTGTAACAAAGGTTTCTACAGTAAAAAGTACTTAAAATCTCATATTATACGGGCACATTTGAAAGTCACTTACCATTGTAAGTTTTGTGATAAAAACTTTAAAGCGAAAGAAAGTTATCGTAGACACATGATAGTCAAACACCCGAATGATAACGACTTAGAAGTTGGGCCCAAGTATATGTGTGAAAAATGTCCTGAAGGTTTTAGAAACGAGTTTGAATTAGCAAAACATATAAATATAATGCACAACGAACCTGAATTCGAAATTAAGAAAGAAGAAGACGACTCGATCAAGACTTCTTTTAAATGTACAAAATGTACTGATGAATTTCTCACATGGGAGCAATTGCGGGCACATTTCGGTGAATCCCACCACTTGACCGAGGAAGTACAGTGTCAAATCTGCGGAGATTTAATGTCCCGATCGGATCTACAGAAACACATAAAGGTCCACGACGAAATCGAAGTCCAATGCAAATACTGCGAGTTTAAGACTAAAAATAAAGTCAGTATGACCCAGCATTTACTACGGCACAAGAATTCTGAAACTTTAAATTGTGATTATCCATTATGCCGCTACAAAACCTTCTACGAGGATGCAATGTTGAAACACAAGAAACGACATGAAGGAACTTCTATTCTATGGAAGCCTGAGATGGAAGCTCTATATGGATCTGGTATGGATGTTGTAAGTGAAACAATTACATATAGACGAGAAGTGATAGGAATAAGACGTTCTGCATCTGCAGGTTCTGCTTCAAAATGCAATTTCTCTTCCCGATTTTATTCGCGTAAATAA
Protein Sequence
MAEEDNSRTIKIFTRRALYEILKEFKGHKMEEKFSLFEDRLVQLTNCPEHEKQRIVNGLKHFKSEFKKKWRGASYKEERFLKSNEVWLTSSMELPNWPEITLPKPGRPKKSFEDVCDRSKRRKTKDLREQVSVEELTYAAGVSQGTSGNKDASKIIKELMASPTRATKLRKVISTSKKQTTVKKYTPAEALAIFVEGDFTRRQWEIINRSGKAIYPCYSVIQMAKIECYPEEESIHVTETSAEVKLQALLNHTALRLYKYIAEVVNTTESSITPPPKKIEQCLATARRAIAAGRNEQYLATARRAIAAARYEQSLATARRAIAATPCSLASSHCGQETLSRQSIGLEKEATKQNTMENMDIEEINRIIRSQEADYNEIKRILTNLKKDPNTRKTDKYINERRARLTEILNRTTTNHELLRNQQVLVDHKYITTSYYESIKSLVNQTMENLAKCEKRLQLLGKLYEPQDIEENECEDANSPKIFIQLYRITQMQKKLQTATQALTEDKPVWYWESLAKNIEKQWQDIEETHLLILMEDSTLDHSYFRDNLFEKTQTDYDVIIERITAKASNTKRVGNSEHKSNLPRIIIPVFDGNYESWDSFYDLFLKIIHEDKSLSATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAKHVDNILNIAKINHATAANLKSLHDTINQNIEALRRQNIDTTTWDPILGRILSRVWDSETNEKYEQQLTEPKKPQKIDEMMEFLEKRFQCLQTTTTISKQTKTNYKTRYDTPGPYKRSDNNHCWYCNKKPYHTIYQCIQFKQLSVEERYKAVKEKGICRNCLAHSQSEECMSTKTCQHCGRLGHHSYLHQENHKPTRYTKNEKTNTSKNTTTTRTNNMHTNTTTTLPKTTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCTETVAQLLAYPRNRTHVEVTGIADEKPKIANYSIEVKLQPRFPSEFKLITTLIILPKLTGAIPSTNIPQLEERQLENKMIADPTYNKRGPIDVILGAQDYSKLLLQGLYKINDDIIAQDTHFGWILSGFVSSHTTDRMKIGTACIDRGVFRIETNFEKEQIEQNLRQIKKAVTQFDDLCEIAKNTTKNATHCEQFHHYLKESESKYERTKEYLMEANQTKRKKRGILGQILTSVFGVNDEVYRDIDSLNKNQQQLIEAANQQTKFMISTVSQVNETENRITKKLQKFQTKLNQVIQFIHETDYWYQAVIRNSVNIHIIETYQLANDYITEITEHYAGLLDVYLSKSSVYSILTPKNVSNLIYTANNKLPSNLKIVQRQLLETKMAENETHIQVYAYFPIQDTTKYTMIYVTAVPEKTRDQLFQTVEIQKSYIGVDYNNEQYFDLDHEEFTSCLQSMSTYVCFPSAVKNMQSNDNCIVNQLFKNQTQTRCQSKTFDITNKLLWKQLHMQNTWLFIAKDRSLTSIICDGQREEIELRDVGVIRIADNCIIKTTNNILAAKRTISVQTVASFSKPIDFSISTYNSTGTIFNVTKDEVIESSQDILDNVVKSENNLQTKLDNTIWTQFPHIDDEYQDSNENSQPEPIVKFDEQNKEAVLLTFESVINEKILYGEPIESIDHDFDNEQVEPAELAMSFLCKICHLVFKTQKTLVQHQKRTHKRFRRTFKHKCEHCGMQYEFKNSLEAHKKRRHSPNSVIDDMMERTCDICALVFKGVNRLRMHMRRTHGSFEDAFKHVCQDCGLTYDKTQSLLVHRKRKHPTVKKPKVTQWFNCLFCPKVFTRRETYTRHVQRKHKVDDDNVGTKGKIKSEKSEIGETTCMYCSLVFSSVGYLNWHLRRKHNVKIDDYKLKCKICNLSYNKVESLKRHIKRKHTQDNYCSVCCKQFTSKSSYINHTHIKQVQECNLCGQIFAHQGGLAKHLRCTHKIETPATVFCNMCNKGFYSKKYLKSHIIRAHLKVTYHCKFCDKNFKAKESYRRHMIVKHPNDNDLEVGPKYMCEKCPEGFRNEFELAKHINIMHNEPEFEIKKEEDDSIKTSFKCTKCTDEFLTWEQLRAHFGESHHLTEEVQCQICGDLMSRSDLQKHIKVHDEIEVQCKYCEFKTKNKVSMTQHLLRHKNSETLNCDYPLCRYKTFYEDAMLKHKKRHEGTSILWKPEMEALYGSGMDVVSETITYRREVIGIRRSASAGSASKCNFSSRFYSRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-