Basic Information

Gene Symbol
-
Assembly
GCA_907269075.1
Location
OU026112.1:2819422-2821029[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.12 9.5 7.5 0.2 5 23 57 76 53 76 0.91
2 14 0.00069 0.054 14.6 1.7 2 23 82 104 81 104 0.95
3 14 0.0014 0.11 13.6 1.5 1 23 109 132 109 132 0.94
4 14 0.33 26 6.1 0.1 2 23 135 157 135 157 0.93
5 14 0.0053 0.41 11.8 1.0 2 22 164 184 163 184 0.95
6 14 0.021 1.6 9.9 0.8 1 23 240 263 240 263 0.89
7 14 0.19 15 6.9 0.0 3 23 292 313 290 313 0.91
8 14 0.31 24 6.2 0.4 2 23 336 359 335 359 0.94
9 14 0.00031 0.024 15.7 0.4 3 20 366 383 364 387 0.90
10 14 0.011 0.89 10.7 0.4 1 23 392 415 392 415 0.97
11 14 0.00023 0.018 16.1 0.2 2 23 421 443 421 443 0.94
12 14 2.5e-05 0.002 19.1 4.7 1 23 447 470 447 470 0.98
13 14 0.00038 0.03 15.4 0.5 2 23 477 498 476 498 0.96
14 14 0.018 1.4 10.1 1.9 1 23 504 527 504 527 0.95

Sequence Information

Coding Sequence
ATGGAGATAAAAATTGATATTTCTAATATAAACTGTGAAGTTTGTTGTCAGAATTTTGATTCTGTAGATGATGTTGTTAGTCATCTTGTTTTGGTTCATAAGTTGGAGTATGATATCGATGTAGATATGGCTACAGAGGAATACAGACTTGCTGATCTTAATTGCATAGTTTGCAATGAGAAATTCACTTATTTCGGCTATTTAGTCTCACACGTCAATATAAATCATCCTAAAAACTGTTTGATTTGCGACAAATGTGAGCAGAAGTTTAATAAAAAGAGAGACCTGTTCTCCCATATCAAGAATTATCATAGAGAAGGAGGGTATCAGTGCGAATATTGTCCCCAAAGCTTTAATTCCCTAAATATATTAAGAAAACATAGAAGCAATAGGCATGTCGCGAGTTGTAGCATCTGTCAGTTGAGATTACCATCTGCAGCTTTGAAGCAAAAGCATATGGAACTCGAACATCCCGATGACGGTTGTCTTCAATGCGATAACTGTGCTAAAGAATTCCACACAAAACAGGGCTTAAGAATGCATCTTCGAAAATGTAAAGGAGAGTACGAATACATCATCAAAAAAGAAGATCTAACTATGGATTTGGATCAGAACTACGATTTAACGAAACGCCCAACAGTGAAACAAATTAGAGAGAATATAGTGACAGTGATTAATATGTCTACGGCTATACCTTTTAATTTTTACAAGAATAAGTTTAACTGCTTCTATTGTTCGAAAGATTTCCAAGATTCGGATTTGATGCGGGAACATACGGTATTAGAACATCCAGTTTGCGATGTTAAAGATGATTGCATAAGGAAATGTAAGGAATCAGTCGCGTGCGTCAAAATAGACATTTCAACACTAGCCTGTAAAGTCTGCTTTGAATCCTTACCAGATTTGGACAGTCTGCTTGATCATTTGATCGCGAAACATGACGCCAATTACGATAAGAACATTACAACTTGTCTTCAGCCTTACCGTCTTATCAAAGACCATATGACTTGCCCGAACTGTCCGGAAGAAATCTTTCGTTTCTTCGGTACTTTATTAAAACATGTAAATAAAAAGCACACAGATAACAATATCATTTGTGTTTACTGCGGGGAAACGTTCCGTAGAGACCAGAACTTGCGCGTACACATCTGGCGACACCATAGAGACGGTAGATTCAAATGCAATATTTGCGATGCCGAGTGCAATATACCATCACGTCTATACATGCATATGGCTAAAGCTCACGGTGTAAAAGCAGCTAAATGTCCGAAATGCCCCGAAAGCTTCGCAACTCAGTATTTAAGGCAGAAACATTTGATAGAAGCTCACGATTCGGGCCACAAATGCTCATATTGTGGGAAGCTATTTACGAGAAATTCCTTCATGAGGGACCATATCAGACGGACTCATCTTAAAGAGAAAAACGTGGAGTGTTCCATTTGTAATATGAAGTTTTTCAACAATATTCTATTAAGGCGGCATTTGGTAAGACATAGTGGAGAGAAAAACTTCCACTGCGAAGTATGTGGAGAGAGATTTTTCTGGAGGAAGAGTTTAAGGACTCATATTGTGAGGAATCATAAGCAGTTGGAGGCTATTCATATGTAA
Protein Sequence
MEIKIDISNINCEVCCQNFDSVDDVVSHLVLVHKLEYDIDVDMATEEYRLADLNCIVCNEKFTYFGYLVSHVNINHPKNCLICDKCEQKFNKKRDLFSHIKNYHREGGYQCEYCPQSFNSLNILRKHRSNRHVASCSICQLRLPSAALKQKHMELEHPDDGCLQCDNCAKEFHTKQGLRMHLRKCKGEYEYIIKKEDLTMDLDQNYDLTKRPTVKQIRENIVTVINMSTAIPFNFYKNKFNCFYCSKDFQDSDLMREHTVLEHPVCDVKDDCIRKCKESVACVKIDISTLACKVCFESLPDLDSLLDHLIAKHDANYDKNITTCLQPYRLIKDHMTCPNCPEEIFRFFGTLLKHVNKKHTDNNIICVYCGETFRRDQNLRVHIWRHHRDGRFKCNICDAECNIPSRLYMHMAKAHGVKAAKCPKCPESFATQYLRQKHLIEAHDSGHKCSYCGKLFTRNSFMRDHIRRTHLKEKNVECSICNMKFFNNILLRRHLVRHSGEKNFHCEVCGERFFWRKSLRTHIVRNHKQLEAIHM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00837839;
90% Identity
iTF_00837839;
80% Identity
-