Basic Information

Insect: Hypselothyrea guttata
Gene Symbol: zfh1
Assembly: GCA_035045125.1
Location: JAWNNJ010001699.1:1479435-1485247[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.7e-05 0.0019 18.6 1.0 1 23 152 174 152 174 0.97

2 15 0.00084 0.06 13.9 1.2 3 23 182 202 180 202 0.94

3 15 9.1e-05 0.0065 16.9 0.1 1 23 368 390 368 390 0.98

4 15 0.0036 0.26 11.9 2.3 1 23 396 418 396 418 0.98

5 15 3.7e-06 0.00026 21.3 2.9 1 23 449 472 449 472 0.96

6 15 0.0006 0.043 14.3 1.9 1 23 508 530 508 530 0.95

7 15 0.07 5 7.8 1.8 1 23 536 559 536 559 0.97

8 15 0.027 1.9 9.1 0.4 3 19 568 584 567 585 0.95

9 15 0.00016 0.011 16.2 5.6 1 23 594 616 594 616 0.97

10 15 0.041 2.9 8.6 1.2 2 23 622 643 621 643 0.96

11 15 9.3e-06 0.00066 20.0 1.0 1 23 652 674 652 674 0.98

12 15 0.0011 0.075 13.6 0.1 3 23 682 702 680 702 0.97

13 15 5.6e-05 0.004 17.6 0.5 1 23 708 730 708 731 0.95

14 15 0.054 3.8 8.2 0.4 1 23 741 763 741 763 0.97

15 15 0.00051 0.036 14.6 0.2 1 23 1263 1285 1263 1285 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.7e-05	0.0019	18.6	1.0	1	23	152	174	152	174	0.97
2	15	0.00084	0.06	13.9	1.2	3	23	182	202	180	202	0.94
3	15	9.1e-05	0.0065	16.9	0.1	1	23	368	390	368	390	0.98
4	15	0.0036	0.26	11.9	2.3	1	23	396	418	396	418	0.98
5	15	3.7e-06	0.00026	21.3	2.9	1	23	449	472	449	472	0.96
6	15	0.0006	0.043	14.3	1.9	1	23	508	530	508	530	0.95
7	15	0.07	5	7.8	1.8	1	23	536	559	536	559	0.97
8	15	0.027	1.9	9.1	0.4	3	19	568	584	567	585	0.95
9	15	0.00016	0.011	16.2	5.6	1	23	594	616	594	616	0.97
10	15	0.041	2.9	8.6	1.2	2	23	622	643	621	643	0.96
11	15	9.3e-06	0.00066	20.0	1.0	1	23	652	674	652	674	0.98
12	15	0.0011	0.075	13.6	0.1	3	23	682	702	680	702	0.97
13	15	5.6e-05	0.004	17.6	0.5	1	23	708	730	708	731	0.95
14	15	0.054	3.8	8.2	0.4	1	23	741	763	741	763	0.97
15	15	0.00051	0.036	14.6	0.2	1	23	1263	1285	1263	1285	0.98

Sequence Information

Coding Sequence: ATGAACAATCAGGACTATGGCGGCATTCAATGGATACAGCAGCACGCCTCTGCCGTTGACTCCGAAACCGAAATGCTGGAAGGcagcgctgccgacgtcgacgtcgaggTGACAGGCGCCTACCTGGTGAACGGCGATGGCACCGACGAGGATCTCGACCATATGGCAGCGGAAAATCTCATTTTCATGGCCCGGGACGGACAGCTAAATGAGATCATCGCTGCCAGCGAAACCGCCGGAGGCACAGTGCTGATAACGGATAGCGATAACGTCACCTACGCCGAGTCCTTTGACGATGAGGCGCAGGTGGTGACGGAGGAGATCATCACGGATGATTGGGTGCAGCATCAGGGCGCCGACTGCGTGGAGATTGCAGCGGAGCAGATCGAGGGCAACACCATCTCCTTGGAGCTGCTGGACATGGAGCAGGATGAGTACACGGCGCTGCGTCCGTATCCGTGCGACTTCTGCAGCCGGCGGTTTCGCAAGAAGGCCAGCCTCAACAATCACATGCTGGCGCATCAGAACGATCGCCCCCATCTCTGCAAGCTGTGCGGCGCAAGATTCTCCCGCCGCGCCGAGCTCATCAGCCACTTCAAGGCGCATGCCGAGGCGCAGGATGCCGCAGAGGCAGAagccgccgcagcagctgccgccgcctccGTTAAATTcgagccgcagcagcagcagcagcagcagcggcaggcgGAGGATCACTTCTATGAGCAGGAATGGCCTTTGTATCAGGATCAGGAACAGCCTGTGATGCAGGAGCagccacagccgcagcagGAGCAACTGAATCTGGCCAATCAGGTGCTGCAGCAGGCCAGCTATGCCACCGTCAGCTCCGTGCCCGCCCCTACCGCTGGGCGGGGTCGCATCAGTCGCCTCAAGCCCAAGGAGGAGACCACGCAATACATTGTGCTGGCCGAGAAGCAATCGGCAGAGGAAGTGCAGCATTACATGAACTGCGACGATCTCTCGCATTCGCCAGCTGACAACGCCACGCCCAGTAATGCCGTCGATGGCAATCACTCCATGGGCGTCCATGGGGCGTCCAATCCCCCTCGCTTCCCCGTGCTGGACGACAGCAAACCCTTCGTGTGCCAGCAGTGCGGACTGGCATTTGCGAGGGAGAAGGCGCTCGTCTCCCATATCAAGAATCATCGAGAGGACTCGCCCTTCGAGTGCAATCAGTGCCAGGAGATGTTCTGGGACACGCACAGCCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAACTCGGAGTACGATCCGGCCTCGGCGGGAGAGGACAGCGCCAGCGAATCGGAACCGGAACAGCTTTACGGCGACTTCTACTGCAGCGAATGCGGCATTTCGTTTCACAGGCAGGATCTGTTGCGACGCCACatgaagcagcagcacaagATGGGCCTCGTGGATGCCGCATTGGCGCTCAACGCAACGGATGCGGAGGGCAGCGGCGACGCAGAGGGGGAGGCGGAGACGGAGGATGCCAAAGATGCGGCACACTGTTGTCACACGTGCGGCAAATCGTTTCCCAGCGCTCTCGAACTGCTCGCCCATGCCGAGATTCATGCACGTTTCCCGCCTTTCAAATGCGTCTTGTGTGGCAGCAGCTTCTACGAGGAGCAGGCCATCAAGCGGCACCTGCACACGCGGCACGCGGGCGAGCTGCGGCCCAACTCGTGCGTGCTGTGCGGCAAGGAGTGCAGGGACCGCAAGGCGCTGATCAAACACGCCTGGGACCATTCGCGGGAGAAGTGCCATTCGTGCTCCAAGTGCGGCAAGAACTTCCACAACAAGGCGCGGCTCAAGCGGCACATGGCATCGCATCGCGACAAGTCCGTGGTCTGCGAGGTCTGCCACGAGGAGTTCCCCGACGGACGCACCCTCTCCAACCATCGCCACTCCCACAGCACAACCTCCCCGGGCAAGCTTTTCCCCTGCCACGAGTGCGGCAAGACCTTCGGCTCCCGCAGCTCCCAGCAGATTCACGTGCGCATACACACCGGCGAAAGACCCTACGGTTGTCGGTACTGCTGGAAGGCCTTCGCCGACGGCGGCACCTTGCGCAAACACGAACGCATCCACACGGGCGAGAAGCCCTACGCCTGCTCCGTCTGTCCCCGTGCCTTCAACCAGCGCGTCGTCCTGCGCGAACACATCCGCTCCCATCACTCGGGTCTGGATGCCGTGCGGGGCACGTACCACTGCACCGTCTGCTCCGCGGATCTCTCCTCCTCCAACGAGCTCATCCAGCATCTCATTCAGCACAGCGACACAAACACCGCCAAACAGCGACAGCCTATTaCGGGTCCCCGGAAATACAAACGTCGCAGAAAACTGCAGCCCCATGAGATCGCGCACATGCGTACGGGTGGCAAGGACGACGAGGAGTTTGGCAGCGACATCGATCTCGACCTGGACGTGGAGAATGTGGATGAGCTGCTGGACGGGGCGGATGAGGCGTCGCCACCCCAAAGCGCCAAGAAGCGCAAGCGCAAATCGGCATCCAATGAGGCGGCAGCTGTCGAACAaaacgcagctgcagctgctccaacgGATCGGCTGTGGGAGGAGAAGTTTACGCAGGCGAATGGCAATCAGCAGCTGAACGACGATGCCTACAAGAGCATCTTCCATATGGACGAAGCATCGCTGGAGATGCTGCCCAAGACGCGGCGCAGCGTCAAGCAGCAGACGAGCAACAAGTCCACAATGACAGCAGgaggagaagcagcagctgctgaggaGAGCAACAGATCAAGCGGGTCTAGTAATCGCAGCAGAAAGAAGAGCAGCACAGCAGCCGGCAGCCAGCAGCGTCCTCGGATGATACACACCGGCAAGTCGCGCGTCTGCCCGGAGGCTGCGAGCAAGAGGAGCCGAGGACGCACCTACAACACGCGCACCAGCAACAgcgagagcaacagcaacagccaggGTCTGGGTCTGGTCAAGTCGCGGATTGTGGACGACTACGAGATTATATCACCCGCCACACAGCCGCCCAACCAGATCAGCTCTAGTCCGCTGCACATcaagcaggagcaggagcagcagcagcagcagcatctgcagcagcagcaacatctgcagcagcagcaacagcaacatcaacaacagcagcaacgcgTGCACCTGCTGTATGATGATGCGCATTTGCTGCTTGGCACGACGCTCATGCGTGAGAAGAACTACGAGAAGTACAATCCCAGTCTGGTCAACGATCTGGAGGAGATCTTTCGCAGTCCGATCAAGCATGATCGCAACGCGCGGCTGCGCTTCACCAGCGAGTCGTCGACGACGCCGCAGTTTCTGCCCGAGGAGGAGCAGAATCTGATCAAAATCGAGCCCACATCGCCAGATCTGCGTGAGATGGTGGAGGGTCAGCAGCGTCTGAGCGCAGCTGCCGCCTCCGCATCCTCATCCTCGTCAGCGGCGCGCACCTCCCGCCACCTGCGTCAGCTCACTGCCAACTCCAGCCTGCGCACGGGCAGCAAAcgaagcggcagcagcaaagcgTTGCCTGCaaccagctccagctccaagaAGACTGCATCCTCGGCCAGCTCCTCGGCGGTCAGCAAATCCAACTCGTATCTCAACTATGGCGTGGACGCCTacaatgtgggcgtggcggccAATGTCGGCGCATCGGATGTCGGCTCTGGATTCTTTTCCATCTCCGAGGTGGTGTCCGCCGCAGATGCCGCAGATGCGGCCGCCAAAGCCGCAGCAGCCAACAAATTTCAGCGTCGGGCACGCTGCTTTGAGTGCGAAATGTGCTCCGCTAATTTCCCGGATCGTGGCCAGCTGCTGGAGCATATGCACATCCACATCTAG
Protein Sequence: MNNQDYGGIQWIQQHASAVDSETEMLEGSAADVDVEVTGAYLVNGDGTDEDLDHMAAENLIFMARDGQLNEIIAASETAGGTVLITDSDNVTYAESFDDEAQVVTEEIITDDWVQHQGADCVEIAAEQIEGNTISLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAAEAEAAAAAAAASVKFEPQQQQQQQRQAEDHFYEQEWPLYQDQEQPVMQEQPQPQQEQLNLANQVLQQASYATVSSVPAPTAGRGRISRLKPKEETTQYIVLAEKQSAEEVQHYMNCDDLSHSPADNATPSNAVDGNHSMGVHGASNPPRFPVLDDSKPFVCQQCGLAFAREKALVSHIKNHREDSPFECNQCQEMFWDTHSLQEHQKTHQFEESNSEYDPASAGEDSASESEPEQLYGDFYCSECGISFHRQDLLRRHMKQQHKMGLVDAALALNATDAEGSGDAEGEAETEDAKDAAHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGSSFYEEQAIKRHLHTRHAGELRPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCSADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRTGGKDDEEFGSDIDLDLDVENVDELLDGADEASPPQSAKKRKRKSASNEAAAVEQNAAAAAPTDRLWEEKFTQANGNQQLNDDAYKSIFHMDEASLEMLPKTRRSVKQQTSNKSTMTAGGEAAAAEESNRSSGSSNRSRKKSSTAAGSQQRPRMIHTGKSRVCPEAASKRSRGRTYNTRTSNSESNSNSQGLGLVKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQQHLQQQQHLQQQQQQHQQQQQRVHLLYDDAHLLLGTTLMREKNYEKYNPSLVNDLEEIFRSPIKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVEGQQRLSAAAASASSSSSAARTSRHLRQLTANSSLRTGSKRSGSSKALPATSSSSKKTASSASSSAVSKSNSYLNYGVDAYNVGVAANVGASDVGSGFFSISEVVSAADAADAAAKAAAANKFQRRARCFECEMCSANFPDRGQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -