Hham013799.1
Basic Information
- Insect
- Hypothenemus hampei
- Gene Symbol
- lola
- Assembly
- GCA_013372445.1
- Location
- JABRWK010000002.1:1440313-1467737[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.0013 0.11 13.0 1.6 2 21 458 477 457 478 0.94 2 8 0.0031 0.26 11.8 0.7 1 22 494 515 494 515 0.95 3 8 0.00029 0.025 15.0 0.1 2 22 531 551 530 551 0.94 4 8 0.01 0.89 10.1 4.3 2 20 567 585 566 587 0.93 5 8 0.0015 0.12 12.8 1.1 2 21 604 623 603 624 0.93 6 8 0.0049 0.41 11.1 3.7 2 20 642 660 641 662 0.94 7 8 8.2e-05 0.007 16.7 0.4 2 21 679 698 678 699 0.94 8 8 0.14 12 6.5 0.1 1 21 714 734 714 735 0.89
Sequence Information
- Coding Sequence
- ATGGACGACGACCAGCAATTTTGTTTACGATGGAACAATCACCAGTCAACGTTAGTAGCGGTATTCGACacattattagaaaatgaaaaactggTGGACTGTACCCTAGCAGCCGAGGGTAAATACCTGAATGCACATAAGGTCGTCTTGTCCGCGTGTAGTCCGTATTTCGAGTCCCTGTTGTCGAGACATTATGACAAACACCCAATTCTGATCCTCAAAGATGTGAAATTCCAAGAACTGAAAGCGATGATGGATTATATGTACAGGGGTGAGGTCAACATATCCCAAGACCAATTGGGGGCTTTATTGAAAGCTGCCGAATCGTTACAAATCAAAGGGCTGAGCGATAATAAACGGGAGGAGCAACAGCCTGTAAAAAGATCCGCGGCTCCCGCACCAGCACCCTCAAAGAGTCCCCAGCCCCAATCGCAATTACCCAAAGTTCAAGGGTTGACGATTGAACAAAGAAATAGGGATGATAgAGAAGGCTCAGTGTCACCAGGTCCTCGGAAGAAAAAACGAATAAGACGGAAAAGTGAAGATTTAGATAATCACCATGATGCCTCCAATTCTTCTGATGCCCACACGCTGCCCTCGACAAACATTCCAACGGCAACTACTCAACTACCTGCTAATATTAAAGTGAACTCAGATGTGCCTGATACCATTGACATGAAACAGGAAATTCTTAGGCATAAGGATGAAATTGGCTCTCAACAATCTCAAGTTCCTAtgatcaaagaaaaattagaaacacaTACAGAATTAATGTTGGAACCGAAATCTGAGTACGTCGAGGAAGCGAACGAGGACAGTATTGAGGACCTGACTTTAGATGATGATGACTTGAGCAACATGGAACAAATGGATGATGGAGCGGGACCTAGTCATGGAGGCGAGGGATCATCACAGCAAGGATTTGGACATTGGCAAATGGGTAATCAATCACAAGACGAGGTATTTTTGGCTGCACAGGAGGCAGTAGGGGCACATAGGGACTCGCAAGATTCAGAAATTTCCATTGTTCCTAATGCCATTCGTATTGGAATGATCGTTCCCAGAGACATAAACACATTAAAAGATCCTGTTCAACTGcCGGAACAATCAAAAGACGAAACAATTATAATGCAAAATAGGGATAAGAAGCAACAAATGTTGAAAGTTCGAGTAAAACCAAAAACTTTTACTTCAAAGTATGTGTGCGAGTGCGgaTTAAAAACCAAAGAACCCGTTACTGGAACCATAAGTTCTGAAAGTAACTCGATGGATCCCTTATTCGAAGATATTGAAATCGAAGCTgaaatgttcaatatttcgGATATATGCAGCGTAATGGATCAGGAGCAAGATAATTTTGATCCTGATATAGTGTGCCAGATTTGTAATACAGCGTTTCGACATATGTCCTCATTGAGATATCACAGAAAGCATCGAGTGTGTTTGAAACCTAAACGAGaggaATTGGAACCAAAAATACATCAATgcgaaaaatgtgaaaaaattttcgCCACTGGTTCTGGGTACAAATACCATGTACGAAGAAGCGTATGCGAACAAGAGGATGAAAAAGAGGAACCCAAGGTACTTCGGTGTCCTATGTGCGAGAAAATATTTGCTACAAATACCggtttaaattatcatttaaaaaggAAAGTGTGCGAGCAAGTCGAAGAAGACAAAGaagaagaaattattaaatgtgaaCATTGCGAAACAGTGTTTAGACATAAGACTTCGTTACATTATCATGTTACCCATAAAGTGTGcttgaaaccaaaaaaagaggATTTCGAaccaaaaactttaaaatgcgATCAATGTGATCGAAATTTTTCTACTACTACTGCATTGACTTATCATGTAAAACACCAAGTGTGTGCTCCGAAAGAACCAAAGGAACCTAAAGTCGAAGAAGAGAAAGAGTGTCATTTATGTAATTCCACTTTTCGACATAATAGCTCATTGAGGTACCATTTGGCTCataaagtttgtttaaaaCCCAAGATAGaaaagaCGGAACCTAAAGTAATGCAATGCGAAAAATGCGATAAAATATTCACGAGTAATACTTCACTGGAGTATCATGTGAAACGAAAAGTGTGTGAACAAATTAAACCAAGTGCTCCCGGACCACCATTTATTTGTGACATTTGTAGTACGTCATTCGATTTACGTCAAACGTGGTATGCCCACGTACAAAGGCAGGCCTGTAGAAAGTATCCGGAGAAATATATGCCAGATACGGAAGTTGATGTTAAAATTGAGcccgaataa
- Protein Sequence
- MDDDQQFCLRWNNHQSTLVAVFDTLLENEKLVDCTLAAEGKYLNAHKVVLSACSPYFESLLSRHYDKHPILILKDVKFQELKAMMDYMYRGEVNISQDQLGALLKAAESLQIKGLSDNKREEQQPVKRSAAPAPAPSKSPQPQSQLPKVQGLTIEQRNRDDREGSVSPGPRKKKRIRRKSEDLDNHHDASNSSDAHTLPSTNIPTATTQLPANIKVNSDVPDTIDMKQEILRHKDEIGSQQSQVPMIKEKLETHTELMLEPKSEYVEEANEDSIEDLTLDDDDLSNMEQMDDGAGPSHGGEGSSQQGFGHWQMGNQSQDEVFLAAQEAVGAHRDSQDSEISIVPNAIRIGMIVPRDINTLKDPVQLPEQSKDETIIMQNRDKKQQMLKVRVKPKTFTSKYVCECGLKTKEPVTGTISSESNSMDPLFEDIEIEAEMFNISDICSVMDQEQDNFDPDIVCQICNTAFRHMSSLRYHRKHRVCLKPKREELEPKIHQCEKCEKIFATGSGYKYHVRRSVCEQEDEKEEPKVLRCPMCEKIFATNTGLNYHLKRKVCEQVEEDKEEEIIKCEHCETVFRHKTSLHYHVTHKVCLKPKKEDFEPKTLKCDQCDRNFSTTTALTYHVKHQVCAPKEPKEPKVEEEKECHLCNSTFRHNSSLRYHLAHKVCLKPKIEKTEPKVMQCEKCDKIFTSNTSLEYHVKRKVCEQIKPSAPGPPFICDICSTSFDLRQTWYAHVQRQACRKYPEKYMPDTEVDVKIEPE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00830519;
- 90% Identity
- iTF_00830519;
- 80% Identity
- iTF_00830519;