Hdol004097.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hyposoter dolosus
Gene Symbol
PRDM1
Assembly
GCA_963921915.1
Location
OY998130.1:18500311-18504234[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 1.9e-05 0.0018 18.7 2.5 1 23 789 811 789 811 0.99
2 5 1.4e-06 0.00014 22.3 3.3 1 23 817 839 817 839 0.98
3 5 1.2e-06 0.00011 22.6 4.2 1 23 845 867 845 867 0.98
4 5 0.00077 0.073 13.7 1.5 1 23 873 895 873 895 0.97
5 5 5.1e-05 0.0048 17.4 0.2 1 22 901 922 901 922 0.96

Sequence Information

Coding Sequence
ATGGAAGCCAGCGAGTGGGATCACGCGACCTTAAGGGAAGAAGAATTCGAACAACATGCAGTTTATTTGGTACCCGATGTCTCGGCGTCGCCCAACGATGCTAATCGCGCCGAAGGATCACTCCCGAGAAATCTCGTTCTCAAACCCTCTCAAGCACTCGACGACATGATGGGCGTTTGGAGCACGAGTTACATTCCCAAAGGGACGCGTTTCGGTCCACTTGTCGGTCAGGTCTACACCAAGGACTCTGTACCGGCTGACGCCAACCGGAATTACTTCTGGAGGgTGTACAAAAACAACGAGTTGTTCTACTACATCGATGGGTATGACGTACAAAAATCCAACTGGATGAGGTACGTCAACCCGGCGTATTCGTCGGAATCTCAAAACCTTATAGCTTGTCAATACAAGatgaacatttatttttacacgatcaAACCGATCCTTCCGAATCAAGAACTCCTTGTTTGGTATTGCCGAGAGTTCGCTGAGAGGCTCAAATATCCACTTACCGGCGAGCTCATGCTGCAACGAATACgaCAACATTTCCAACAATCGACTCTCTCCCCGGAAACAGCACCGACGGTCGAAGTGGTATTACCCCTTAAGGAATCGACGATATACGAAAGGCGTTGTCAAATGACACCAACCGAGGGTTCAGTGAGATCGGACGAGGGTTACAACTCGAACGGTTATCACGACGAGATATTAACACCACCGGAGGAGAGCAGCGAGTCTGATTCGGAGAACAACTACGTGCTCGACTTCAGTAAAAACACGAGAACGTCTGTGCCGAGTAACGAGTTGCGTAGCAAGCAAGACAGCGTGGTAGTGAAGAACGAGTACAGAAAAGTCAAGATAAAGATACCGAAGAGTTACAGCAACAATTTTCAGAGTACGAAAGCAACACTGGACGTTTCGAAGGACAAGGATGATTTGTCGAGTGGTACGGTGACGCCAGAGATTCCTCACAAATCAGTCTCGCCGATGCTGCTGTTGCAAAAACAAACGGTTATTTCGACCTCAAACGACGACGagattatggaaaaaaattcaaagcctTTTTACGAGCCCGAACCAAAGGGCGGATTGCCGATTACAATTTCGAACAATTCAAGGCCGCCATATGTCACGAGTCCGAGCAGTTCTATACTCGAAAATATTCTGCTACGCAGCAGTACCGatagcaacaacaacaacaacaataatccTGGCAACCACAACAACATTataaacaataacaacaacagcagcaataACAACGGAAATGTTCATATTCATCATCACAATTCCATCACGAATTCAATCAGCAATCATCCTCATCAGAGTCACAACCATGGAGTCTACGCGAGTCATTTGGACTCGGTAACTCCTCCACCATCCAGTCCAACCGAGATGGCGTATTCGTACAAAAAGTCCCACAGATATGGCAACATATTGCCCTGCAGTCCAGACTCGAGCTCGAATTTACCGATGAGTACAGAAACTTGTAACACGGTCGTTAATTCGACGAGCAACGTGACGATGCTCCAAAGTCCTGGCAACCTCCACTCGACCAGTGGCAACCCAGTCGTCAGTGCTTCCCATCCCTCCAACAATTCGTTACATTCCAGTATCTCCAACAACCAAACCAACATACATTCGAGTAGCGTATTATCGTCGACAGCAACGACAACCACTACGACGAGTATGAGCCTTTATCCCACCACGACCACCAACGGGCTCGTCATAAAATCGAGAAAGAGCAAAAGTCCTTCCCCCGGTGCTACGACAACAACCAACATTCCAAACTCCTCGAGCACCCCGCCTATCGGTACGAGCACTATTTTGTACTCCGGCTCAAACGTCTCTTCCCCTCATATAGAATCGAGCAATTCAATGTATTTGAACTCTTCGAACAACACGAGTGTCTCTCCCATCTCCCCCATACACTCCCCATCACCTTATCCCTATGGATTGTATCATTCCAACGGTAACATGCATCCGCACGTTGCCCCCTTGTCCATCAACTGCACCGCTTACTCGCCAACTCCTTCCTCAGCTGGCAATTTGAGTTACGAAAGAAACGATGTCAGGAGACACGAGAACGCGAGTGCTCACCAATTACCTACGTCCTCGACCATGCAGATCGATGCCAATCAATCGAACCTCATCGCCGGCACCCACAACTTGCATCTTGGACATCATCCCGGTCTTACGATACACGCCAACTCGTCATCCATCAATCGATACTCTCCTGCGAGCTCCTTGTCACCCGACGATCATGCCTGCTCTCAAAGTGGCTCACTCAGTCCCAACTCGCAAGGCTCACGAGGATACAGATCTTTGCCTTATCccttgaaaaagaaagatggCAAAATGCATTACGAGTGCAATGTTTGCTGCAAAACTTTTGGACAGTTGTCTAATCTCAAAGTTCACCTCAGAACGCACTCCGGCGAAAGACCCTTCAAGTGCAACGTTTGCACCAAGAGCTTCACGCAATTGGCACATCTTCAGAAACATTATCTCGTTCATACAGGCGAAAAACCCCATCAGTGTGAAATCTGCAAGAAGAGGTTTAGCTCAACATCCAACTTGAAAACTCATCTCAGACTTCACTCCGGTCAAAAACCCTACGCTTGTGATCTATGCCCTGCAAAATTCACCCAATTCGTACATCTCAAGTTACACAAGAGACTGCACACTAACGAGAGGCCTTACACGTGTCAGGGTtgtgacaaaaaatatataagcGCCAGTGGACTCAGGACACATTGGAAAACAACGAGCTGTCGACCGAACAATATCGAGGACGAATTGGTTCTCGCAGCTGCGGCAGGATCCCCGAGTTATTACACCGAGTATGGCTCTGACATGAATGTTGGTAATATGCAAAAAGAGTGTGAATTGGAGCACCTAGAGAATTATGAGAGACGAGCAAATGGCCACGGTCCACATTCGACGTCGCTCCACAATCTGGACAGTTCGGTAGGTCGACCGAGTGTAATAGAGTCGTCGCAACCGCACATAATTGAGTGCACATAA
Protein Sequence
MEASEWDHATLREEEFEQHAVYLVPDVSASPNDANRAEGSLPRNLVLKPSQALDDMMGVWSTSYIPKGTRFGPLVGQVYTKDSVPADANRNYFWRVYKNNELFYYIDGYDVQKSNWMRYVNPAYSSESQNLIACQYKMNIYFYTIKPILPNQELLVWYCREFAERLKYPLTGELMLQRIRQHFQQSTLSPETAPTVEVVLPLKESTIYERRCQMTPTEGSVRSDEGYNSNGYHDEILTPPEESSESDSENNYVLDFSKNTRTSVPSNELRSKQDSVVVKNEYRKVKIKIPKSYSNNFQSTKATLDVSKDKDDLSSGTVTPEIPHKSVSPMLLLQKQTVISTSNDDEIMEKNSKPFYEPEPKGGLPITISNNSRPPYVTSPSSSILENILLRSSTDSNNNNNNNPGNHNNIINNNNNSSNNNGNVHIHHHNSITNSISNHPHQSHNHGVYASHLDSVTPPPSSPTEMAYSYKKSHRYGNILPCSPDSSSNLPMSTETCNTVVNSTSNVTMLQSPGNLHSTSGNPVVSASHPSNNSLHSSISNNQTNIHSSSVLSSTATTTTTTSMSLYPTTTTNGLVIKSRKSKSPSPGATTTTNIPNSSSTPPIGTSTILYSGSNVSSPHIESSNSMYLNSSNNTSVSPISPIHSPSPYPYGLYHSNGNMHPHVAPLSINCTAYSPTPSSAGNLSYERNDVRRHENASAHQLPTSSTMQIDANQSNLIAGTHNLHLGHHPGLTIHANSSSINRYSPASSLSPDDHACSQSGSLSPNSQGSRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHYLVHTGEKPHQCEICKKRFSSTSNLKTHLRLHSGQKPYACDLCPAKFTQFVHLKLHKRLHTNERPYTCQGCDKKYISASGLRTHWKTTSCRPNNIEDELVLAAAAGSPSYYTEYGSDMNVGNMQKECELEHLENYERRANGHGPHSTSLHNLDSSVGRPSVIESSQPHIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01102321;
90% Identity
iTF_01101612;
80% Identity
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