Basic Information

Insect: Hyposoter dolosus
Gene Symbol: lolal
Assembly: GCA_963921915.1
Location: OY998135.1:2060047-2076779[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 5.7e-07 5.4e-05 23.5 1.9 1 23 751 773 751 773 0.98

2 8 1e-05 0.00096 19.6 2.4 1 23 779 801 779 801 0.98

3 8 1.9e-06 0.00018 21.9 0.3 2 23 810 831 810 831 0.98

4 8 2.3e-05 0.0022 18.5 0.2 3 23 839 859 837 859 0.97

5 8 2.1e-07 2e-05 24.9 3.0 1 23 865 887 865 887 0.98

6 8 1.9e-06 0.00018 21.9 0.8 1 23 893 915 893 915 0.98

7 8 7.4e-05 0.007 16.9 7.5 1 23 921 943 921 943 0.98

8 8 9.8e-05 0.0093 16.5 1.5 1 21 949 969 949 970 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	5.7e-07	5.4e-05	23.5	1.9	1	23	751	773	751	773	0.98
2	8	1e-05	0.00096	19.6	2.4	1	23	779	801	779	801	0.98
3	8	1.9e-06	0.00018	21.9	0.3	2	23	810	831	810	831	0.98
4	8	2.3e-05	0.0022	18.5	0.2	3	23	839	859	837	859	0.97
5	8	2.1e-07	2e-05	24.9	3.0	1	23	865	887	865	887	0.98
6	8	1.9e-06	0.00018	21.9	0.8	1	23	893	915	893	915	0.98
7	8	7.4e-05	0.007	16.9	7.5	1	23	921	943	921	943	0.98
8	8	9.8e-05	0.0093	16.5	1.5	1	21	949	969	949	970	0.95

Sequence Information

Coding Sequence: ATGATGGGCGAAGTGATAAGAGTATCAGGACGAGCTCCGGATGTCGGTGACCTTCTCAGAGAGGCCATGGTGTCACAGAGATTCGCTGATGTAGCTCTTTGCTGCTCAGGTGGACagagatttttggcacatcgaCTTGTTCTTTCGGCTGCAAGTCCGTATCTGCAGGATGTTTTGTTGGCCCATGGGAAAGCAGCAGGATCCAGTGAACCGATAACGATAATTTTGGCGGAAGTAGAAGCTCCAGAATTGTCAGCGATATTGGGTTTCGTGTATACCGGAAGTGCGACCATACCAAAATCTCGTTTAGAGGCATTTACACGTGCGGCAGAGACACTGCACGTGAGGATTCCAACGTTTGGTTCGCCGGTCAGATTGGACGTTGGTAATTACGAAATATTATCATCCTCGTGTAACCACGAGCTCGATTGCAAGTTTGATTGTTTAAAAGTCGAAGAGACGACGAGATTAAAGGATGCGAGATATTTTCGCTGTGAGCAATATCCGTCCTGGGAAGGTTGGTTGAGTCCTTCGGATTGGCATTATCATCGCGAATGTACGAGACGAGTTTTCCAACCTGAAGACTGGATACTAAGAAGCAAAGAAAATGGAGCTTTACAGAGACAAAGCGAAGCCGAAGCGCCGGCATTCTCCGAGAACGTTGAAGCAACGAGCAGGAAACATTTGCCTCGAGAAAGCTTTGAAAAGAGTGTTGATGGCGTTGAGACTTCAAGAAACGAGGGATACAGCGAGAGACGAGAGTCTCCGTGGATCGAGGGCGATTCCTCGGTCTCAAATCCTAGCAGTGTCTTCCTTGATCCATCGAAATCGATACCTGAAATTCGCAAGGAGCCCAAAAACTACGAATTTCCGGTTCAAGCTCGTCAGGGACTCGAAGCTTTGGTTGACCCGCGATCCAAGCTCGTAGATTCTTTCTCCGTGACCGGAAACTATAGCTCGAGAACAAACCTCGATTCCTGCAGAgtttacgaagaaaattctcaaGAAAACAGAGATTTGGAGCCTCGATCGAATCTCAAGTTCGATAAATACGATTACGAGCATTCCTCCTCGTTCTCATCGAAAGTTCCAATTAGTCCCTCGTCGAATCTTCAGCCTGGCACAAAAATACTCTCCGAAACAACGGTCTCTTCCAACATCCCTTCACAATTTACTACCAACCTTACAAATTTAACGATTCCatcaaaaaactcgaatttctgCAGCGATTATTGCTGCACGTGGAGAACACCGAAAAGACACGTTGCCAATCGCGTGCCAGCTTCGCCTTGGTGCCAACTCGCTCGACCGGCTCATCATTCTCCAAAAACACGGCCCATCCTCCCACGCAATCCGAACGAAAACGTCGAGCCGTCAGCTCATCCAGACTGGAACGGTACTGTTCTTCCGAACGAAACGCTTACTCGAGGATTTTCGTCATCGAGAGCAACTTACGTGGAGAAGAATCAAGTTGGTGCTGGATCTTTGCATCAAAATTTGGAGGGGAATGCATCGTCGGATGGTACGGGAGGAATTTATGGTTTTCGAGTTCCTAAAAGCGTCGATGAGGAATGTACGGATTATTCGAAACAACCGGGAAGtcgagacgaaattttttatgacgaaaagtcttacgaaaaatcatcgacaTTTCCTGCACGAGGAAATTTCTCCACGGAGAATTTTCCAAAGGAAACAATTTCGCAGGAAGttgttcgatcgatcgaaaagcCCTGTGCGCTCGTCGATATCCTTCAGGACCAATCGCGTCCTCAGCAAAGCAACGAAGCTTCAAATATAATCGTGAATCACGAAGAATCGCGCGTTAGAATTTCTCAACACGCGATCCCGCCTCCGGCACATCCTAACAAGCAAATAATCAACGATCCTTCGTCATGCAATCTCCAAACGTCACCGAGAATCGAACTTTCTCATCCGATAAGTCGGCTTTGTGATTCTGTCCGTAATATCGACGATTCCATCTGCCGCGaaccatttttcatcgataaagATACGTCGGAATTTTCGTCCCTGGGGATTCAACCGATCGAACAGAAACTCAAAGATTCTTTGGATCGAAGCAAAACCAACTTGTCAATTTCTCATGTGATCCTCCAAAgcgacgacaacaacaacgagcCTGGAATCGACGACCCCGTCGTCGATATTTCAACGAATCCTGATGTTCGTTCGAGCGGAGATGTTAACGAAAGTGCCACGGTGGACGATGGGATCGGTAACGGGGAGGATCACAAATGTGAACAATGTGGAAAAACTTTCGTCACTCGAGCGTCTCTCAAGGTTCATGGTCGTACACATTCGGGGGAGAAACCATTTCGTTGCACGGACTGTGGCAAGGAATTTTCGCAGTTGCGGAATTACAAGTATCATCGTAGCGTGCACGAAGGTACAAGAGAATTTGCGGCAACATGTCCCGAATGTGGAAAGTATTTCAACGACCGTGGTTACTTGAGTTCTCACATGAAGATCCATCGGAATCGTAAAGAGTACGGGTGTTCGGAGTGTGGCAAGAGTTTCAATCAGCGAGTAGCTTATAACATGCACGTGCGTATCCACACAGGTGTAAAGCCTCATCAGTGTGACCAATGTGGCAAAGCATTTTCCCGAAAGATGTTGTTGAAGCAACATTTGCGTACACATTCGGGTGAACGTCCGTATCAATGCCAAATTTGTCAGAAGGCATTTGCGGACAGATCGAACATGACGTTGCACACGCGGCTTCATTCTGGCCTCAAACCTTATCAATGCACCCTTTGTTCCAAAGCATTCACCAAGAAACATCATTTGAAGACTCATTTGAATTATCACACCGGTACAAAACCATATTCTTGTCCAAATTGTTCCTTGCGATTTTCCCAGAGCAGTAACATGAGGACACACTATAAAAAGTGTTGTTCCATGGCAGGGATCGAAGGATTCGATCGCCACGAAGCCACAGCCGGAAGTGaggaaaagaataaagagCCAGGAGGTCAAGCGTTGCTCGTAGCCTCGGGCATCGAAGTTCCTTCGGTCGGAGGCCGAACGAACGCCTTAACGCCTCCCAATTCTGACCAAGAATCCAGCATCCAAACCCCGACGAAAATAAACCCAGCAATTGCATTGCGCTCGACTTGCCGTCCTCGGAAAATAGACATCAATGTCCTTCTTGACACGTGA
Protein Sequence: MMGEVIRVSGRAPDVGDLLREAMVSQRFADVALCCSGGQRFLAHRLVLSAASPYLQDVLLAHGKAAGSSEPITIILAEVEAPELSAILGFVYTGSATIPKSRLEAFTRAAETLHVRIPTFGSPVRLDVGNYEILSSSCNHELDCKFDCLKVEETTRLKDARYFRCEQYPSWEGWLSPSDWHYHRECTRRVFQPEDWILRSKENGALQRQSEAEAPAFSENVEATSRKHLPRESFEKSVDGVETSRNEGYSERRESPWIEGDSSVSNPSSVFLDPSKSIPEIRKEPKNYEFPVQARQGLEALVDPRSKLVDSFSVTGNYSSRTNLDSCRVYEENSQENRDLEPRSNLKFDKYDYEHSSSFSSKVPISPSSNLQPGTKILSETTVSSNIPSQFTTNLTNLTIPSKNSNFCSDYCCTWRTPKRHVANRVPASPWCQLARPAHHSPKTRPILPRNPNENVEPSAHPDWNGTVLPNETLTRGFSSSRATYVEKNQVGAGSLHQNLEGNASSDGTGGIYGFRVPKSVDEECTDYSKQPGSRDEIFYDEKSYEKSSTFPARGNFSTENFPKETISQEVVRSIEKPCALVDILQDQSRPQQSNEASNIIVNHEESRVRISQHAIPPPAHPNKQIINDPSSCNLQTSPRIELSHPISRLCDSVRNIDDSICREPFFIDKDTSEFSSLGIQPIEQKLKDSLDRSKTNLSISHVILQSDDNNNEPGIDDPVVDISTNPDVRSSGDVNESATVDDGIGNGEDHKCEQCGKTFVTRASLKVHGRTHSGEKPFRCTDCGKEFSQLRNYKYHRSVHEGTREFAATCPECGKYFNDRGYLSSHMKIHRNRKEYGCSECGKSFNQRVAYNMHVRIHTGVKPHQCDQCGKAFSRKMLLKQHLRTHSGERPYQCQICQKAFADRSNMTLHTRLHSGLKPYQCTLCSKAFTKKHHLKTHLNYHTGTKPYSCPNCSLRFSQSSNMRTHYKKCCSMAGIEGFDRHEATAGSEEKNKEPGGQALLVASGIEVPSVGGRTNALTPPNSDQESSIQTPTKINPAIALRSTCRPRKIDINVLLDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00829662;
90% Identity: iTF_00829662;
80% Identity: iTF_00829662;