Basic Information

Insect: Hyposoter dolosus
Gene Symbol: mecom-a
Assembly: GCA_963921915.1
Location: OY998135.1:3042478-3060398[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.001 0.096 13.3 0.1 2 23 110 132 109 132 0.95

2 9 2 1.9e+02 3.0 0.4 1 23 139 162 139 162 0.92

3 9 0.00012 0.012 16.2 0.7 1 23 168 196 168 196 0.93

4 9 1.3e-05 0.0012 19.3 2.7 1 23 202 224 202 224 0.95

5 9 2.6e-05 0.0024 18.3 5.1 1 23 230 252 230 252 0.99

6 9 0.034 3.2 8.5 0.9 2 21 260 279 259 280 0.95

7 9 7.6e-10 7.2e-08 32.6 1.2 1 23 663 685 663 685 0.99

8 9 8.3e-08 7.9e-06 26.2 1.7 1 23 691 714 691 714 0.97

9 9 8.1e-06 0.00077 19.9 3.4 1 23 720 742 720 742 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.001	0.096	13.3	0.1	2	23	110	132	109	132	0.95
2	9	2	1.9e+02	3.0	0.4	1	23	139	162	139	162	0.92
3	9	0.00012	0.012	16.2	0.7	1	23	168	196	168	196	0.93
4	9	1.3e-05	0.0012	19.3	2.7	1	23	202	224	202	224	0.95
5	9	2.6e-05	0.0024	18.3	5.1	1	23	230	252	230	252	0.99
6	9	0.034	3.2	8.5	0.9	2	21	260	279	259	280	0.95
7	9	7.6e-10	7.2e-08	32.6	1.2	1	23	663	685	663	685	0.99
8	9	8.3e-08	7.9e-06	26.2	1.7	1	23	691	714	691	714	0.97
9	9	8.1e-06	0.00077	19.9	3.4	1	23	720	742	720	742	0.99

Sequence Information

Coding Sequence: ATGAATTTGTTGTTGCAGGTCCGCATAGCCGGAAGCGGCGTAAGAGGATGGTTGGACGCTTCGCACGAGGCCGGAAATTGGTTAAAGTTCATCAGAAGCACAGCGAATCCACACGCCATAAATATTCGTCACGTGCTCATCAACGGGCagGTGGTGTACGAATCGGTGAGGGACATAGCGATCGGCGAAGAGTTGCTTCTTGGTCTTCGGGAGCCTCTCCAGCTTCAGGACATGCTCGGAGAGAACACAACCGAAGACAGAAGTGATCGAGAGACCGCTTCCCAACACAGTGGAACGGTCGAGGAGGAAGAGTCGGAAACGGAAATCCGATGTACCGTCTGTGACAGACCCTTCAAGGACATTGAATTATTGGACAATCACTTGGTAACGAGTCATCGTTATCCATCGGATCAGCACCGGTGTGAGACTTGTCCAAGCGGATATTCCTGGCGTCCGTTGTTGGTGCGTCATCGGGCAGTGAAACACGGAGATTTGCGAAAGTATTCGTGCGAGAATTGTCCAAAGTCGGAACGTCCGCAGGTTTTCACGGACCCATCGAATCTCCAGCGTCACATACGGGACCGTCACGTAGGAGCGCGAAGTCACGCTTGCACCGAATGCGGAAAAACTTTTGGAACGAgctcgggattgaaacaacacacgcacatacacaGCAGCGTAAAGCCATTTCAGTGCGAGGTTTGCTTGAAATCGTACACACAATTCTCTAATTTGTGCCGTCACAAACGCATGCACTCGGACTGTCGTATGCCAATAAAGTGCGTCAAATGTAGCCAATTGTTTAGCACAGTGACTTCGTTGACGAAACACAAACGGTTTTGCGACTCTTCGAGCGGTGCTCGACCTTCGACAGGAGCCATGCCACAGTTACCGGCTTCGGGACCAAGTCCCTATTTGGTATTTCAACGACCTAGTGTCTCGCTCTCCGGTTGCTTGCCATTTTATCCACCCTATCCAGGAATCTTTCCAAATGGTCCTAATTTCCTCAACGCGCCGTTGCTCTTCCCGCCCAAAGttcagcaacagcaacaacaacaacaacatgcGCAAGCGCAACAATCGCATCAGCAAATGAAGCAACAGGCCCAACTGCATCACTCCGAACAGCCGGAGAAAAGAAGCGAAAGTCCAAAGAAGGAGCGATTTACACCGCCGAGACTGTTGCCCCAACACAACAAAGTCTCACCGTCGACGGCTGAAGAAGCGACTTCGACGTTGAGACCATCGCCAGCGAGACCAGCGATCCCATCGACAATGGAAACGGAGGACGAGTCATCGAGGCGACGAGACCAACAGCGAGAggcaaaaagaaagagaatctcTTCGACGGAATGTGCGACCTCGTCATCGAACGAAGAAACCGATCAGCCGCTGGATCTCCGGGTTCAAACGAAAAGATTTAAAGAGGATTTGGAAGTGATTGAGCGAGGAAACGCCGAGCCAAGTCCGAGCAACTCCCCGTCGACGCCTCTCATGGAGGAATCAACGGTCGAAACCTCGAGGCACtcggaagaggaagagaacgcgatgcaaataaacgaaacgaaagaaatttcaagtcCGCAATTGCGGAATAGCTCCCAAGAGCAAAACCCTTCCGGGACACCTCCATACATGGCGTATCCCAGGCCAATCCACCCCCAAACACAAGCCATGTTTCTCGAAGCCATGTATCGCAACACCAGTCCGGGGTTTCCTGGATTTCCCGGTGGACCAACCCCGCCCGGTTGCTCACCAGAGTCCCGACTACTTCCCCCTCTACCACCCTTCGGACCACCCCGTGGGCTGCCTTTTTTAGGCAACATAATGAACGGCCTCAGTGGCGCTAGACCCGGAGGGAGTTTTGATCTTTTGACGCGACCATCGATGAGCTCCTTCCCCGGTGTCAAGCCCTTTCAAGATGCAGTCATGTCCcaccaccatcatcatcaacaCCATCACCACCCTGGCAAAATGAAAGATCGATACACGTGCAAATACTGCGGCAAAGTCTTTCCACGTTCTGCCAATTTGACTCGGCATCTTCGAACTCATACAGGAGAGCAACCGTACAAATGCAAATATTGTGATCGATCTTTCAGCATATCGAGCAATCTGCAGCGCCACGTTCGCAACATCCACGACAAGCAACGACCCTTCAAGTGTCCATTGTGCGAGCGTTGTTTCGGCCAGCAAACCAATCTCGATCGTCATCTGAAGAAACACGAGGCCGACGATGGCAGCGGTGTCGTATCGGTCGCGGACTCGCCAGGCAGCAGCAACGAAAACGAACGAGAAGACACCTACTTCGATGAGATCAGATCCTTCATGGGCAAAGTAACGTACAGCGGAGATCCGGTCTACGGTCTCGATCGCCACGCTCGACCGACCTACTGCACAATGCCTGAACGCCTCAGAATCGGCGAAGAATCTGATGTCAGCGAAGAGGATGTTTCGCCACTTGAGGAAACCGATGCCATGTCTCCTCTCGGGACCAAAGAATCACCTCCACCCTCGCAGTACGAACTTGAGTTCAGAGACAAACCGGAACTCTTGAACAACAATACCGCCTCGCCCGTCATCGAAATCTCTACATAG
Protein Sequence: MNLLLQVRIAGSGVRGWLDASHEAGNWLKFIRSTANPHAINIRHVLINGQVVYESVRDIAIGEELLLGLREPLQLQDMLGENTTEDRSDRETASQHSGTVEEEESETEIRCTVCDRPFKDIELLDNHLVTSHRYPSDQHRCETCPSGYSWRPLLVRHRAVKHGDLRKYSCENCPKSERPQVFTDPSNLQRHIRDRHVGARSHACTECGKTFGTSSGLKQHTHIHSSVKPFQCEVCLKSYTQFSNLCRHKRMHSDCRMPIKCVKCSQLFSTVTSLTKHKRFCDSSSGARPSTGAMPQLPASGPSPYLVFQRPSVSLSGCLPFYPPYPGIFPNGPNFLNAPLLFPPKVQQQQQQQQHAQAQQSHQQMKQQAQLHHSEQPEKRSESPKKERFTPPRLLPQHNKVSPSTAEEATSTLRPSPARPAIPSTMETEDESSRRRDQQREAKRKRISSTECATSSSNEETDQPLDLRVQTKRFKEDLEVIERGNAEPSPSNSPSTPLMEESTVETSRHSEEEENAMQINETKEISSPQLRNSSQEQNPSGTPPYMAYPRPIHPQTQAMFLEAMYRNTSPGFPGFPGGPTPPGCSPESRLLPPLPPFGPPRGLPFLGNIMNGLSGARPGGSFDLLTRPSMSSFPGVKPFQDAVMSHHHHHQHHHHPGKMKDRYTCKYCGKVFPRSANLTRHLRTHTGEQPYKCKYCDRSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYSGDPVYGLDRHARPTYCTMPERLRIGEESDVSEEDVSPLEETDAMSPLGTKESPPPSQYELEFRDKPELLNNNTASPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00266682;
90% Identity: iTF_00266682;
80% Identity: -