Basic Information

Insect: Hyposoter didymator
Gene Symbol: zfh1
Assembly: None
Location: scaffold67:3437368-3451893[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.027 2.3 8.7 1.1 2 23 65 87 65 87 0.92

2 7 7.4e-06 0.00064 19.9 0.6 2 23 107 128 106 128 0.97

3 7 4.6e-06 0.0004 20.6 7.8 1 23 137 159 137 159 0.99

4 7 0.00029 0.025 14.9 4.5 1 21 165 185 165 186 0.95

5 7 7.2e-05 0.0062 16.8 4.2 1 23 641 663 641 663 0.94

6 7 1.8e-05 0.0015 18.7 7.3 1 23 669 691 669 691 0.98

7 7 0.0012 0.11 12.9 4.3 1 21 697 717 697 718 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.027	2.3	8.7	1.1	2	23	65	87	65	87	0.92
2	7	7.4e-06	0.00064	19.9	0.6	2	23	107	128	106	128	0.97
3	7	4.6e-06	0.0004	20.6	7.8	1	23	137	159	137	159	0.99
4	7	0.00029	0.025	14.9	4.5	1	21	165	185	165	186	0.95
5	7	7.2e-05	0.0062	16.8	4.2	1	23	641	663	641	663	0.94
6	7	1.8e-05	0.0015	18.7	7.3	1	23	669	691	669	691	0.98
7	7	0.0012	0.11	12.9	4.3	1	21	697	717	697	718	0.96

Sequence Information

Coding Sequence: ATGCCCTCGCCTGTTGACGAAACTTTCCCATCTTCCCATCGATATCACATTATAGTTTTGCGACTACCGAAACTTTTAGGTGGTGGGGGCGGAGGAGGGGGAATCGGCGGTGGTGAAGGCGTTGGAGGAGGCGCCGGTGTCGCCAGTAGTGGCGGCACAGGAGGCGAGTCCGGCTCGGCGAAGCAAGGCGAGAGATGCCCGCAGTGTGGCATGATCTGTAGAAATTTACACGTTCTTCAGCTTCATCTCGAAGACATTCACAAAACTTCATTCGCGAGCATCGACAAGCACGATCTCAGCGCTCAATTCTCCCAAGTTTCGTGCAAAGTGTGCAACAAAACATTTGCGAACGTCTATCGTCTTCAAAGGCACATGATCAGCCACGACGAAAGCGCAGTTTTGCGTAAATTTAAGTGTCCACACTGTGAGAAGGCCTTCAAGTTTAAGCACCATCTGAAGGAACATCTCCGAATTCACAGCGGCGAAAAACCATTCAAATGCCACAATTGCAGCAAACGTTTCTCTCATTCGGGCTCGTACTCGAGCCACATGACGTCGAAAAAATGTTTGATAGTAAATTTGAAAAAAACCCGACAGACTTCGACAGCGAGTGTCGATCGCGTGGCAAAAAAGTCACAACAGAATCTCGTCAACTCCCGCAGAGATCCCGTCGACCTTCACGTCTCAAACAACAATACTTTCATGCCCATTTTACCGAAATTGTCACCCTCGGACTATCAGGATATACAACGAGAAGGAGCAGGGATCTACGACATGCCGACACTTTTACCTCAAATGATGGGCTTCGGTAGTTATTTTTTGCAATCGTCAATCGGTAAAATTCTCAACCAATTGCACACGAAACGATTGGACGAGGTTGCAGAACAATTCGAGACTCATCGCGAGGTGATGAGTCCTTCGACCGCTGATTCCGAAGGTACCGAAGGCACCGAAGGCAAAAATTCACCATTGCCGAACGATCCTCAAGGCCTTGATGCTGTCAGACGAATTCTCGAGACCGTCAATACCTCAGTTACGAAACAATTGCTCGAGGCGAACGTGAGGAAATTAGCCTCGTCTCCTGTCACCATAAAGCGAGAATACGATCAGGATTATCAGGATCAAGACAGCGAGATGTCGAGCGAGATGACTCACAGTCAAGACTGGCATGCTGCCGATCAATGTGATTCTCAGAGCGAAGGTCTCGCTGCAAAGCTCGAAGACGTTAATCGACCGGCGTCGGAGCGCCAGAGTTACAAGAGAAAAGCAGATGACAACGGTGTCGAAAGTTCCGAGGGTGATACGGAGGACGAAGAGAGCACACAGCCGCAAAACGAATCAGGCAGAAGAGTAAGAGCTCGCTCGTTAATCGATGACGAACAATTGGCCGTCCTTAAGGGTTATTACGCGATAAACCCTCGACCTAAAAAAGAAGAAATTGCAATGATAGCGAATTACATTAATTTTCCAACTCGAGTCGTTCAGGTTTGGTTTCAAAATTCACGAGCGAGAGATCGAAGAGAATCAAAAATCCCGGCACTCTTGCCATTGGCCAACTTCACCAATCACAATAATTTCGAGCAACCGCTCGATCTCTCAAAAAAAGATGCTTACGCGATATCGCTCGTCAAGGACAGCGACGGCGGATCTAGCAGACATACCGCATCTCCCTGCGGACCTAAAGAAGAACCAATTCGTCCTGTTTCTCAACCTCGCAACGATGTCGAAGACGTCGATGATACGCCACTTGTCATCGACGAGGAAACCCCTGACTCTGTTGAACCCAAGAAAGTAGAGCCCGTTATCAAAGAGAAAAGTCTCCCCAAGAGCCAACCCGTAACTGTTACGAAAACCACCGAGCCCGTAGTCAACACAACGACCGAACCACCTCCACCTGCCGAGAACGAGCAAGAAGGTTTATACTTTTGCGATCAATGTGACAAAACATTCTCGAAGCACAGTTCACTTGCCAGACACAAGTACGAACATTCCGGTCAAAGGCCTTACAAATGCGAGGAATGTCCTCGTGCGTTTAAGCACAAGCATCATCTTACGGAACACAAGAGACTGCACACCGGTGAAAAACCTTTCCAGTGTTCCAAGTGCCTGAAGCGATTTTCCCATTCGGGTTCCTACAGTCAACACATGAACCATCGTTACTCCTATTGCAAGCCGTACAGAGAATAG
Protein Sequence: MPSPVDETFPSSHRYHIIVLRLPKLLGGGGGGGGIGGGEGVGGGAGVASSGGTGGESGSAKQGERCPQCGMICRNLHVLQLHLEDIHKTSFASIDKHDLSAQFSQVSCKVCNKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFKCHNCSKRFSHSGSYSSHMTSKKCLIVNLKKTRQTSTASVDRVAKKSQQNLVNSRRDPVDLHVSNNNTFMPILPKLSPSDYQDIQREGAGIYDMPTLLPQMMGFGSYFLQSSIGKILNQLHTKRLDEVAEQFETHREVMSPSTADSEGTEGTEGKNSPLPNDPQGLDAVRRILETVNTSVTKQLLEANVRKLASSPVTIKREYDQDYQDQDSEMSSEMTHSQDWHAADQCDSQSEGLAAKLEDVNRPASERQSYKRKADDNGVESSEGDTEDEESTQPQNESGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIAMIANYINFPTRVVQVWFQNSRARDRRESKIPALLPLANFTNHNNFEQPLDLSKKDAYAISLVKDSDGGSSRHTASPCGPKEEPIRPVSQPRNDVEDVDDTPLVIDEETPDSVEPKKVEPVIKEKSLPKSQPVTVTKTTEPVVNTTTEPPPPAENEQEGLYFCDQCDKTFSKHSSLARHKYEHSGQRPYKCEECPRAFKHKHHLTEHKRLHTGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00266735;
90% Identity: iTF_00266735;
80% Identity: iTF_00828675;