Hkah009289.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hyposmocoma kahamanoa
Gene Symbol
-
Assembly
GCA_003589595.1
Location
NW:1271-23423[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 6.3e-07 2.8e-05 23.9 1.2 1 23 10 32 10 32 0.99
2 18 3.9e-06 0.00017 21.4 2.7 1 23 38 60 38 60 0.99
3 18 2.6e-06 0.00011 22.0 2.6 1 23 75 97 75 97 0.98
4 18 6.3e-05 0.0028 17.6 0.6 1 23 112 134 112 134 0.98
5 18 3.6e-05 0.0016 18.4 3.1 1 23 149 171 149 171 0.98
6 18 2.5e-07 1.1e-05 25.2 1.5 1 23 186 208 186 208 0.99
7 18 0.00011 0.0049 16.8 2.8 1 23 214 236 214 236 0.98
8 18 3.6e-05 0.0016 18.4 0.1 1 23 243 265 243 265 0.99
9 18 7.9e-06 0.00035 20.4 2.1 1 23 271 293 271 293 0.99
10 18 0.025 1.1 9.4 1.8 1 23 300 322 300 322 0.98
11 18 4.2e-07 1.9e-05 24.4 2.3 1 23 328 350 328 350 0.99
12 18 0.11 4.7 7.5 1.8 1 23 357 379 357 379 0.98
13 18 1.7e-06 7.7e-05 22.5 1.5 1 23 385 407 385 407 0.99
14 18 0.00033 0.015 15.3 0.7 1 23 414 436 414 436 0.99
15 18 1.9e-06 8.5e-05 22.4 1.9 1 23 442 464 442 464 0.98
16 18 0.0014 0.062 13.4 0.3 1 20 470 489 470 492 0.93
17 18 2.7e-05 0.0012 18.8 1.4 2 23 499 520 498 520 0.96
18 18 2.5e-06 0.00011 22.0 1.4 1 23 526 549 526 549 0.97

Sequence Information

Coding Sequence
ATGAAACTTCACTCCGGAAATAAACCCTTCCAGTGCACGGTTTGCGACGCAGCATTTTGCCGCAAGCCGTACCTGGAGGTCCACATGCGCACGCACACTGGCGAACGCCCCTTCCAGTGCGACCTCTGCCTCAAAAGATTTACGCAAAAATCCAGCCTTAATACGCACAAGCGCGTACATACCGATGAGCACATGCGCGCGTTGATGGTGAAGGACCGCCCCTACAAGTGTGAGCTCTGTCAGATGCGGTTCACGCAGAGCTCCAGCCTCAATCGCCACAAGAAAATTCATACCGAGGAGCACAGGCGCGCGCTGCTGGCTAAGGAACGCCCCTACCAATGCGGCATCTGCTTTGTGAGATTCACCCAGAAATCGAGTTTGGGCCGGCACGGAAAAATACACACTGAGGAGCACAGACGAGCCCTGTTAGAGAAAGCGCGGCCGTACCAGTGCCACATCTGTTTTATGCGCTTCACTCAGAAGTCCAGCCTGGGCCGACACGGAAAGATACACACTGAGGAGCACATCCAATCGCTGATCAACAAAGTGCGCCCCTATCAATGCGACATCTGTGACAAGCGGTTCACGCAGAAGTCCAGCCTGGGCACTCATAAACGTATACACACCGGCGAGCGCCCGTTCCAGTGCACCGTCTGCCTCAAGTCCTTCACGCAGAAGTGCGCGCTCAATTTGCACGAAAAGATACATACGGTGCAAGGGCGCCCTTACTCGTGCGGGCAATGCCCGGCCGCGTTCGCTCGTCGGCCCTACCTGGACACTCACATGCGCACGCACACAGGCGAGCGGCCCTATCAGTGCGACGCGTGCCTCAAGCGCTTCACGCAGAAGTCCAGCCTCAATATTCATAAGCGGACGCACACAGTCCAGGGCAGACCGTTCCAGTGCCTGTCGTGTCCCGCCGCCTTCACGTGCAAGCAGTACCTCGAGATTCACACGCGCACCCACACCGGCGAGCGACCGTATCAGTGCGACATCTGCCTCAAACGCTTCACGCAGAAATCCAGTCTCAACATCCACAAACGGACGCACTCAGTGCAAGGGCGGCCCTTCCAGTGCCTGTCGTGTCCTGCGGCCTTCACGTGCAAGCAGTACCTGGAGATCCACAACCGCACGCACACCGGCGAGCGACCTTATCAGTGCGACGTATGCCTCAAGCGATTCGCGCAAAAGTCCACACTTAACATACACAAAAGAACGCACACAGTGCAAGGGCGCCCGTACCAATGCATGGAGTGCCCGGCCGCGTTCACATGCAAGCCGTACCTCGAGATCCACATGCGAACGCACACCGGCGAGCGGCCCTTCGAGTGCGACGTTTGTTACAAACGGTTCACGCAGAAGTCCACTCTCAACATTCACAAACGCATACATACTGGAGAACGACCGTACGCATGTGATATTTGCCAAAAGCGTTTTGCCGTCAAGAGTTACGTAACAGCTCACCGGTGGTCGCACGTTGCGGACAAGCCGCTAAACTGCGACCGGTGCTCTATGACGTTTACATCAAAGTCTCAGTTCGCACTGCACATCCGCACGCACTCCTCCGGCTCTTGCTATGAGTGCAGCGTTTGTGGACGCACTTTCGTGCGGGACAGCTATCTCATCAGACACCACAACCGTGTGCACCGCGAAAACCACAGCAACCTGTCCGCAAACAGCATCTCGAATCTTGCCAGTGTCGCCACCAACACCAACAACTCGAGCAACAGCAACTTTGACAACTCCGCCGTCTGCGATTTGAGTTTCGTACCCATGGTGAACCGGTACATGACGTCGCAGGGTACCCAGGTGTCGATGCAGGACAACTCCAGTAAGATGTCGGCTTTGTCGCCCCAATCCATCGCTTCTATTTCGTCGCCCCCTCCACCGCACACGCCGACGCCACAGCCACAGATGCCCGGACAGATGCACCTCACCGACTGA
Protein Sequence
MKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCLKRFTQKSSLNTHKRVHTDEHMRALMVKDRPYKCELCQMRFTQSSSLNRHKKIHTEEHRRALLAKERPYQCGICFVRFTQKSSLGRHGKIHTEEHRRALLEKARPYQCHICFMRFTQKSSLGRHGKIHTEEHIQSLINKVRPYQCDICDKRFTQKSSLGTHKRIHTGERPFQCTVCLKSFTQKCALNLHEKIHTVQGRPYSCGQCPAAFARRPYLDTHMRTHTGERPYQCDACLKRFTQKSSLNIHKRTHTVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICLKRFTQKSSLNIHKRTHSVQGRPFQCLSCPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYQCMECPAAFTCKPYLEIHMRTHTGERPFECDVCYKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSMTFTSKSQFALHIRTHSSGSCYECSVCGRTFVRDSYLIRHHNRVHRENHSNLSANSISNLASVATNTNNSSNSNFDNSAVCDLSFVPMVNRYMTSQGTQVSMQDNSSKMSALSPQSIASISSPPPPHTPTPQPQMPGQMHLTD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00041088;
90% Identity
iTF_01076785;
80% Identity
-