Basic Information

Insect: Hyposmocoma kahamanoa
Gene Symbol: -
Assembly: GCA_003589595.1
Location: NW:680088-694655[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 1.8e-06 8.2e-05 22.4 1.7 1 23 149 171 149 171 0.98

2 20 1.3e-05 0.00058 19.8 3.4 1 23 177 199 177 199 0.98

3 20 9.1e-08 4e-06 26.5 2.1 1 23 205 227 205 227 0.99

4 20 0.00017 0.0075 16.2 3.3 1 23 237 259 237 259 0.99

5 20 2.9e-05 0.0013 18.6 2.3 1 23 265 287 265 287 0.99

6 20 0.11 4.9 7.4 0.2 1 23 293 315 293 315 0.91

7 20 0.00011 0.0048 16.9 2.0 1 23 321 343 321 343 0.93

8 20 2.9e-07 1.3e-05 24.9 1.0 1 23 349 371 349 371 0.99

9 20 0.0013 0.057 13.5 3.9 1 23 377 399 377 399 0.94

10 20 1.3e-06 5.8e-05 22.9 1.6 1 23 405 427 405 427 0.99

11 20 0.051 2.3 8.5 2.1 1 19 433 451 433 454 0.91

12 20 0.016 0.69 10.1 3.3 1 23 667 689 667 689 0.96

13 20 2.9e-06 0.00013 21.8 1.7 1 20 695 714 695 717 0.92

14 20 2.2e-06 9.8e-05 22.2 0.9 1 23 722 744 722 744 0.98

15 20 9.9e-05 0.0044 17.0 5.8 1 23 750 772 750 772 0.97

16 20 5.3e-05 0.0023 17.8 0.7 1 23 778 800 778 800 0.97

17 20 8.9e-06 0.00039 20.3 1.6 1 23 806 828 806 828 0.97

18 20 8.5e-06 0.00038 20.3 5.9 1 23 834 856 834 856 0.96

19 20 0.00023 0.01 15.8 2.3 3 23 864 884 862 884 0.98

20 20 7.1e-05 0.0031 17.4 5.4 1 23 890 913 890 913 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	1.8e-06	8.2e-05	22.4	1.7	1	23	149	171	149	171	0.98
2	20	1.3e-05	0.00058	19.8	3.4	1	23	177	199	177	199	0.98
3	20	9.1e-08	4e-06	26.5	2.1	1	23	205	227	205	227	0.99
4	20	0.00017	0.0075	16.2	3.3	1	23	237	259	237	259	0.99
5	20	2.9e-05	0.0013	18.6	2.3	1	23	265	287	265	287	0.99
6	20	0.11	4.9	7.4	0.2	1	23	293	315	293	315	0.91
7	20	0.00011	0.0048	16.9	2.0	1	23	321	343	321	343	0.93
8	20	2.9e-07	1.3e-05	24.9	1.0	1	23	349	371	349	371	0.99
9	20	0.0013	0.057	13.5	3.9	1	23	377	399	377	399	0.94
10	20	1.3e-06	5.8e-05	22.9	1.6	1	23	405	427	405	427	0.99
11	20	0.051	2.3	8.5	2.1	1	19	433	451	433	454	0.91
12	20	0.016	0.69	10.1	3.3	1	23	667	689	667	689	0.96
13	20	2.9e-06	0.00013	21.8	1.7	1	20	695	714	695	717	0.92
14	20	2.2e-06	9.8e-05	22.2	0.9	1	23	722	744	722	744	0.98
15	20	9.9e-05	0.0044	17.0	5.8	1	23	750	772	750	772	0.97
16	20	5.3e-05	0.0023	17.8	0.7	1	23	778	800	778	800	0.97
17	20	8.9e-06	0.00039	20.3	1.6	1	23	806	828	806	828	0.97
18	20	8.5e-06	0.00038	20.3	5.9	1	23	834	856	834	856	0.96
19	20	0.00023	0.01	15.8	2.3	3	23	864	884	862	884	0.98
20	20	7.1e-05	0.0031	17.4	5.4	1	23	890	913	890	913	0.97

Sequence Information

Coding Sequence: ATGGCATCGCCCATGGATGAATCTAACATGTACAGTGATGCAGTGTTTAAGTCCATATATGTAAAAATCGAGCCTGTACTTGACGATGAGCTCAACAGCAATGACCTTAATAGCATGGCAATCGagtttgatttaaaattagatagagataaaaagaaaactgAGAATGTGTCAAAAACTGATGCAGTACATCAAAATTGGAATATGGAAACCGATCAAAGATATATGGAAAAACTGAATATGGAACCTATCAATGATACAAATGCCACAGAAGTGACAGAGAAACAAGATCCTTTAGATCagtcaattgaaataaaaaagaattatttgtaCCCTAAATGTGTAATTAATGAAACTACGGAACTGATCAAATTACGTGAAACTGATGCTTCACAGAAAAGAAATAATGATATTGAAAAAGACTTAAAAGATAACGACAAAAAATTCAAATGTGAAATTTGTGACACACgggtaaaaaacaaaaagaatttagAAAAACACATGAAATTACACAATGGCGACAAACCATTTGTGTGCGAACTTTGTAACAAACAATTTAGAGAGAAACATAATTTACAGACGCACACACGGATTCACAGTGGAgagaaaccatacaaatgtgacttttgtaacaaatattttgctGATAAAAGTAATTTGCAACGTCACTTACGTGTGCACGATGTAAACCACAAAGctaaaaaaattttcacatGTGATATTTGttctaaaacatttatttggaATAGCTGTTTGATTAAACATCGTCGGACGCACATAGATCAAGATGTATATACATGTGAGATTTGTAGCAAACAATTCAAGGAAAGAAACAACTTCTTCTCTCACATGCAAGTTCATACAGGAGAAAAACCTTTCCAGTGTCCGGTTTGTAACATGTATTTTCCTGTCAGAACCAGTCTAGACTTTCATTTATTAATCCACAGTGACACAAAACCATTTGCTTGTGGTGTTTGTGgtaaacaatttacaaataagCGAGGATTACAAAAGCATGAATACCATCACAGTGATGTAAAACCATTTAAGTGTGATATTTGCAACAAGGAGTTTACACAGGAAGTCAATCTGACTAATCATAGGAGGATTCATACTGGAGAGAAgccatttaaatgtgaaacATGTAACAAACGGTTCACACATTACAGTGCATGGCTACGTCACAATTTCATTCATACAGGAGAAAAACGTTACAAATGTGAAGTTTGTGACCAAGATTTTACAAGACGGAGTAGTTTGGTACGTCATCAGTTTACACATACTGGATACAAACCTTTTTCGTGCGACGAGTGTGATAGAAAGTTTGTGCAAAAACAACGGTTTCTTGAACATAACTGCGGACGGAaagctaaaattaaatattcagaTAATGATGAACAATATCATACATCAcacgaaaagaaaataaaaaagactattTCGGATAGACCAAGGCGGCAAACAAGACAAAGGAAATATTCTGATTACGCTACAGACGAGTCTGAAACTGGTGAGGGCAATGTTgtGTGGTGTAACTGCATGTTTTGGTCTGTAACTAATATTGATCTACATACTCACGTCTACAAAAACTTAGCAATGTCTGACCTGGAAATTAAAGCTGAGGAGAGAAGGTCTGATGACAGTTCTGATAGCATATACATGAGTATAAAAATGGAACCAGAATCAGCAGACGATGAAGAACGGAGTCGAGTTATAAAGAAAAATCCTGGAGGCTCAGAACACAGCTATCTAGACTCCGATTGGGAGGTACAAATTAAATTGGAAACTCTGgatcaagaagaagaagaacaaatAACAGTTGAACCAGATTTATATGAACATGAGGTCAAGGAAGACCCAACCCTTGCAGCGTTGCAACAGCCTGAGAACTCTTGCTACGATATCAATGTAGATTTTATAAGTGACAGTGAACAAATAGACGATGCGTTGCAAGAAGAATTGTCAATCCAAGAGAGTGGTAGTAAAGGAAAGAAAAAATTCCAATGTCGAACTTGTCTGAAATCATTTTGTTCAAAGCAGTATTTAGGTCAGCATGAGATAATACATACGGGAGAAAGGCCGTTTGTATGCAAGATCTGCGGCAGGAGTTTTACCAAGAAAGATTATTTACGTAGACACACATGGACTCATACGGGTAATCAGTTCACGTGCAACATTTGCAACAAAGGGTTTGCTCGTAAGGAATCTCTTAAAAGCCATGAAATGAGTCACACTGGCGAAAAAACATTTATGTGTAACATTtgtcacaaatattttacgagacagcagaatttgaatttacatTTGTTGCATCATAGCGGCGAGAAACCATATGCCTGTAACATTTGTAACAAACGATACACTTTGAAACGGAGTCTTAACGCTCACGTGTTGAGACATACAGCTGAAAGAACATTCGCATGTGATATTTGTAACAAAAGCTTTATGGATAAACATGGTCTCAAGAATCATGCAAGGAGTCATACCGGAGAAAAACCACATTCatgtaatatttgtaacaaacgttttacaagaaaacataaCCTTAATTTGCATTTAAAGGCTCATACCGGTGAGAAACCGTTTGGATGTGATATTTGTAACAAGCATTTTATagataaacaatattataaacaacatttattgACTCATAGTGAAGAGAAAAAGTTCGTATGTGATATTTGTAAGAAATGCTTCTCTATTAAGAAGTatcttaaaaaacatttaatgaaGAAGCATTCTAGGCTTGTCCATGGAAGATCAAAGCGAGTTATTAAATAA
Protein Sequence: MASPMDESNMYSDAVFKSIYVKIEPVLDDELNSNDLNSMAIEFDLKLDRDKKKTENVSKTDAVHQNWNMETDQRYMEKLNMEPINDTNATEVTEKQDPLDQSIEIKKNYLYPKCVINETTELIKLRETDASQKRNNDIEKDLKDNDKKFKCEICDTRVKNKKNLEKHMKLHNGDKPFVCELCNKQFREKHNLQTHTRIHSGEKPYKCDFCNKYFADKSNLQRHLRVHDVNHKAKKIFTCDICSKTFIWNSCLIKHRRTHIDQDVYTCEICSKQFKERNNFFSHMQVHTGEKPFQCPVCNMYFPVRTSLDFHLLIHSDTKPFACGVCGKQFTNKRGLQKHEYHHSDVKPFKCDICNKEFTQEVNLTNHRRIHTGEKPFKCETCNKRFTHYSAWLRHNFIHTGEKRYKCEVCDQDFTRRSSLVRHQFTHTGYKPFSCDECDRKFVQKQRFLEHNCGRKAKIKYSDNDEQYHTSHEKKIKKTISDRPRRQTRQRKYSDYATDESETGEGNVVWCNCMFWSVTNIDLHTHVYKNLAMSDLEIKAEERRSDDSSDSIYMSIKMEPESADDEERSRVIKKNPGGSEHSYLDSDWEVQIKLETLDQEEEEQITVEPDLYEHEVKEDPTLAALQQPENSCYDINVDFISDSEQIDDALQEELSIQESGSKGKKKFQCRTCLKSFCSKQYLGQHEIIHTGERPFVCKICGRSFTKKDYLRRHTWTHTGNQFTCNICNKGFARKESLKSHEMSHTGEKTFMCNICHKYFTRQQNLNLHLLHHSGEKPYACNICNKRYTLKRSLNAHVLRHTAERTFACDICNKSFMDKHGLKNHARSHTGEKPHSCNICNKRFTRKHNLNLHLKAHTGEKPFGCDICNKHFIDKQYYKQHLLTHSEEKKFVCDICKKCFSIKKYLKKHLMKKHSRLVHGRSKRVIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -