Basic Information

Gene Symbol
-
Assembly
GCA_964007245.1
Location
OZ023310.1:4904650-4908973[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.0097 0.89 11.3 0.7 1 23 74 96 74 96 0.94
2 20 4.2 3.8e+02 3.0 0.7 2 23 101 122 100 122 0.83
3 20 0.53 48 5.9 0.2 3 23 154 174 152 174 0.96
4 20 0.65 59 5.6 0.1 1 23 200 223 200 223 0.78
5 20 0.038 3.4 9.5 5.1 3 23 231 251 229 251 0.96
6 20 0.42 38 6.2 2.0 3 23 309 329 307 329 0.97
7 20 7.9 7.2e+02 2.2 0.1 2 23 356 378 355 378 0.89
8 20 0.00028 0.025 16.2 0.5 1 23 399 421 399 421 0.95
9 20 0.0073 0.67 11.7 0.3 1 23 425 447 425 447 0.96
10 20 2.8 2.6e+02 3.6 0.3 2 23 536 558 535 558 0.93
11 20 0.076 6.9 8.5 1.2 1 23 607 630 607 630 0.96
12 20 2.5 2.3e+02 3.7 0.1 2 12 727 737 726 740 0.88
13 20 0.7 63 5.5 1.1 1 23 770 792 770 792 0.95
14 20 0.066 6 8.7 2.2 2 20 797 815 796 818 0.92
15 20 0.0027 0.24 13.1 2.0 1 23 825 848 825 848 0.95
16 20 0.0014 0.13 13.9 0.6 1 23 853 876 853 876 0.98
17 20 0.0008 0.073 14.7 1.7 1 23 882 905 882 905 0.97
18 20 1.5 1.4e+02 4.4 3.5 1 23 911 933 911 933 0.97
19 20 3.2e-06 0.00029 22.3 0.4 1 23 940 962 940 962 0.99
20 20 7e-05 0.0064 18.1 0.8 1 23 968 990 968 991 0.95

Sequence Information

Coding Sequence
ATGTCAAGCCATCCGCTGAAATCGGACAAACTCGATATATTTAAGAATTCTCGACCAGGTGAAAGTGTCAAAACTGACATCGCGGATCTTAAATGCGATCTGTGCGAGCAAGATATTGACGATATACCGACACTAATGGACCATATTTACGAGATTCACAAAAAACCCATAGCTAATAACTTTGATTCGGGTATCGTTCCTTACGTTTTAGCGAATGGATTCACCTGCGCACTATGCGGCAAAAGTTTCGATCATTTTGCTATACTGAATGAGCATATGTTTGCCCACGTCCCCAAGTGCGCTTGTTCCGAATGTGGAAAAGAAATCGCCGTAGATAAACTTAAAAGGCATGTTCTCCGAACACACTCAGGCGGATATAAAGACGGTCGGCATAATGCTATTCTTATCTTCGAATTCTCTAACGCGTGTCCTTTCAAATGGCAAGGGAACGTTTTTGGTTGTGCTTACTGTACTTTCACTTCGCCTGAATTCACCGATTTAAAAATACACATGAGTGTTCACCCCATTAATGAGACATTCAAATCTTATACGCTTCGAGTGCAGCATCTAAACGAGGAGCACGGCAAGAAGATAGAGTATCCTTGCAAGATTTGCTCGGAAGTATTCCAAACTGTTGCCAAACGTGCAGGTCATGTCAAAAATGTCCACAGGAAAGACAAATTGCAACACTGTTCCATTTGTAACTACACGTGCTTGACCGCATCCAAATTGAAAAGGCATATGATAAGGCACGGTGATCTTAGGCTTTGTAAAAATCAACTGACgacgtattttcttttgtttatagACCCTGGCCAATGGAGACCGAAACTGGGCGACTATCGTGACGGGCGCGACAATGCAACCATTATACTAGGGTGTTCCAACGTCCTCCCCTTCAAATGGCGTCGAAACGTGTTCGGCTGTCCGAGCTGTGACTTCACCTCGCCCGATTTCACTTGCCTCAAAAACCATATGACAAATCATTCGGTCAAATCAAATAAACTCGATGTTCTTAAGAAGTCCCGACGAGGCGATCCCATCAAAATTGACGTTGCGGAGCTTAAATGCGATCTGTGTGAGCGAGAAATTGACGATATACCGGCACTAATGAACCATTTGCACGACTTTCACAAAAAACCCATCGTGAAAAATTTCGATTCGGGCATCGTTCCTTATTTGCTCGGAAATGGATTTGTTTGCGCGTACTGCGGCAAAGCATTCGATCGGTTCGTTACTTTAAATACGCACGTGTTTAACCATATGCCTAAGTACGCTTGCTCTGAATGTGGGCTACTTTTCTCTGCGGACAGGCTTAAAAAACACATGCTTCGAAATCACGATAAAAGTCGCGAAATAAAATTCAAGCCGAAATCAGGCGAATATGACGTTCGACATAACACCGCTCTCATTTTGGAGTTTTCTAACATCTGCCCTTTTAAATGGCAACGGAATGTTTTTGCTTGCGCCTGCTGCGCTTTCACTTCCGCAGAATTTATTGATTTGAGAATGCATATGAGTGCCCACCCCGTTAAGCCAGAGAAACTCGAAATACTTCGTCATTTGCTACCAAACGACATTGTCAAAGCTGATATCACCGATCTGAAGTGTGAATTGTGCCAACAAAATAtcgaaaatatacaaaaactaatgaCTCACCTGAAAGACGACCACGATAAAcctattttaaaacaatttggcTCGGGTATAATACCCTATTTTCTGAGGGACGGATTCAAATGCGCCTACGGTTCCTGTAACGAATTGTTTGATTCTTTTAACAAACTAAACATGCATATAAAATGTCACAATGTTAAGTATACCTGTGCACAATGTGGACAGTATTTTACCAGTGGGAAAAGGATGAATACCCATTTGATTCGGAAGCACGGGCAATCTCAACTTACTAAATTGAGATCCGAATGCGACAAACTCAAACCTGGATTGAGAACCAAATTCAGTCTATACGACGATGCCAGGGCTAATGCGGCCATAATTCTGGAATTTTCTAACGCATGTCTGTTTAAGTGGCACCGAAATGTATTCGGATGTGCCACTTGTGATTATACTGCAGCGGACTTCGGGCTGTTTAGATCTCATGTTGAAACTAAATGCAAAGGCCTGCAATTGCGCTACTCTCGGCTCACGGACTTGCTGAAGGCTGAAGTTACAGATCTCAAATGCAAACTCTGTGATGAGGCTTTCTACGATCTGAAAATATTACTTTGCCATTTAGGCGAGATACATAATAAACCGATAAAGGTAGAGCACGACACTGGACTCATTCCTTACCTGTTGAGTTCCGGCTACATCTGCGCCTACTGTGGAGTTCAATTTGACGGCTTTACAAAACTAAATTGTCACATGAATGAGCATTTTCCTAATTGCGTTTGCTCCTATTGTGGGCAAGGTTTCACCAGCGAGACTAGATTAAAATACCATACCTGGCAGCATAAACGCAGAATGGAGAGTTTCAAATGCTCCGTGTGCAAAGAGAATTTTGCAACAAGACACCTGAAGCAAAAACATATGATAGCTGAACATGGCAAGCTTACCTACAAATGTCCTTACTGTAGCGAGATGTTCAAGTCTTACCCACTCAGAGTGCAGCATTTGAACACGGAGCACGGCAAGAAGATAGATTATCCTTGTAAACATTGCTCGGAGGTATTCAAAACGTCTGCCAAACGTGGAAAACATATCCGGAGCGTTCACAGGAAAAACGAACTTCACTATTGCTCCGTTTGTAATTACACGTGCTTGACAGCAGCCAGATTGGGAAAGCATATGTTAAAACACGGTAGCACTGAAAGGAACTACAAATGCGACATCTGTTTTAAGGCTTACCCGAGGAGGAGCGCACTGTCTCTGCATATGCGTATACACGACAATGACAATCGGTTTATTTGTGTATACTGTGGCGCCGCGTTTGTGCAGATATCTAGTTTGAAGAGTCACACCAAGACTCACCATCCGTAA
Protein Sequence
MSSHPLKSDKLDIFKNSRPGESVKTDIADLKCDLCEQDIDDIPTLMDHIYEIHKKPIANNFDSGIVPYVLANGFTCALCGKSFDHFAILNEHMFAHVPKCACSECGKEIAVDKLKRHVLRTHSGGYKDGRHNAILIFEFSNACPFKWQGNVFGCAYCTFTSPEFTDLKIHMSVHPINETFKSYTLRVQHLNEEHGKKIEYPCKICSEVFQTVAKRAGHVKNVHRKDKLQHCSICNYTCLTASKLKRHMIRHGDLRLCKNQLTTYFLLFIDPGQWRPKLGDYRDGRDNATIILGCSNVLPFKWRRNVFGCPSCDFTSPDFTCLKNHMTNHSVKSNKLDVLKKSRRGDPIKIDVAELKCDLCEREIDDIPALMNHLHDFHKKPIVKNFDSGIVPYLLGNGFVCAYCGKAFDRFVTLNTHVFNHMPKYACSECGLLFSADRLKKHMLRNHDKSREIKFKPKSGEYDVRHNTALILEFSNICPFKWQRNVFACACCAFTSAEFIDLRMHMSAHPVKPEKLEILRHLLPNDIVKADITDLKCELCQQNIENIQKLMTHLKDDHDKPILKQFGSGIIPYFLRDGFKCAYGSCNELFDSFNKLNMHIKCHNVKYTCAQCGQYFTSGKRMNTHLIRKHGQSQLTKLRSECDKLKPGLRTKFSLYDDARANAAIILEFSNACLFKWHRNVFGCATCDYTAADFGLFRSHVETKCKGLQLRYSRLTDLLKAEVTDLKCKLCDEAFYDLKILLCHLGEIHNKPIKVEHDTGLIPYLLSSGYICAYCGVQFDGFTKLNCHMNEHFPNCVCSYCGQGFTSETRLKYHTWQHKRRMESFKCSVCKENFATRHLKQKHMIAEHGKLTYKCPYCSEMFKSYPLRVQHLNTEHGKKIDYPCKHCSEVFKTSAKRGKHIRSVHRKNELHYCSVCNYTCLTAARLGKHMLKHGSTERNYKCDICFKAYPRRSALSLHMRIHDNDNRFICVYCGAAFVQISSLKSHTKTHHP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-