Basic Information

Gene Symbol
-
Assembly
GCA_003709505.1
Location
PKRV01000322.1:1892718-1902340[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.011 0.71 10.5 4.4 1 23 130 152 130 152 0.98
2 13 0.00018 0.011 16.2 1.1 2 23 157 178 156 178 0.96
3 13 0.018 1.2 9.8 0.6 1 23 182 205 182 205 0.93
4 13 4.8e-06 0.0003 21.1 1.4 2 23 222 243 221 243 0.97
5 13 5.8e-06 0.00036 20.9 2.1 1 23 250 272 250 272 0.94
6 13 0.00012 0.0078 16.7 6.8 1 23 278 300 278 300 0.97
7 13 6.6e-06 0.00041 20.7 3.7 1 23 306 328 306 328 0.99
8 13 2.3e-08 1.5e-06 28.4 1.1 1 23 334 356 334 356 0.95
9 13 2.4e-06 0.00015 22.1 2.9 1 23 362 384 362 384 0.98
10 13 5.8e-06 0.00036 20.9 0.5 1 23 390 412 390 412 0.97
11 13 0.011 0.7 10.5 8.5 1 23 418 440 418 440 0.97
12 13 1.3e-06 8.3e-05 22.9 1.0 1 23 446 468 446 468 0.98
13 13 0.00083 0.052 14.1 0.2 1 20 474 493 474 496 0.94

Sequence Information

Coding Sequence
atgttagATATAACTTCCTCGTGTAGAACATGTATGAAGGAGAATGTGAATTTGATTGACTTATATGAAGTGGTGAAAATTGAAGAAAATTGCCATCAGTGGGCAGATATATTGGTGATTTGTACTCCAACACAGgtCTCCAAAGAAGATGGTTTACCACAAAAACTCTGTGAAGAGTGTGCAAGAATTCTGCAACTTATATATACATTCCGTATTCAGGCTGAGAAAGCTCAAGAGGAGTTCCAAAAACTCTTACAAAATGCAATAAAGACTGAGCCACCAGAAGTGACCCCCAAAACAGAgaatgatgataattatttgcATAGCTTTGATGATACTGATATTAATCATGATGACCAAAAAACAGAAGacattgaagaaaataaatttacatgcagcaaatgtaataaaacctttttaaaagagaaaaagtttttgaaacatCTGCAAATGCATGAATCACCGTTACAATGTACTATATGTAACAAACCATATCATAATCAGGCATCTTTAGACAAGCATTTAGCAAAacataataaagattatttatgttTGGTCTGCAATATGAACTTCCAAACTGAATCACAATTATTTGAACATAGTACAACtgaacacaataaaataaaaattaaactggaAAATGAGGCACAGGAAACACTATTACAATGCCCTGATTGCGACCTTACTTTTACAAAACAGAGATCTTTGTCTATGCACAGAAGaaggcataaaaataaaaataatgagtttaTCTGTGATACTTGTGGCAAAACTTTCAGTATGAAACATCAATTGAAAAGACATGTGGTCTTGCATAGTGATGTCAAACCCCATGTGTGTACAAAGTGTTCAAAAAGTTACGCAAGAAAGGACCAGTTGGTGCATCACATGCATTCACACAAAGACAGTAAACCGTATGAATGCTCATATTGTAagaaagGTTTTACACAACTGTGCAGTTTGAAGGACCATATTCGTAGTCACACTGGAGAAACTCCATTCTTGTGTTCTGAGTGTGGGAAAGGCTTCACTAACAGCTCTAACTTAAGACAACATATGATGAGGCACACAGGGCTGAAGCCTTATGCCTGTAATATGTGTCCGAAGACCTTTTGTACCAAGGGACAAATGACATCCCACATGTCGACCCACACTGGTGAACATCCATACAAATGTGAGGAGTGTGGCGCTGCATTCACCAAACAGAACTCTTTGAAGAAACACTCGCTGATACACTTGGGGATAAAGCCGTTTGCTTGCGAAACTTGTAATATGAGGTTTACATGCAAAGACCATTTGAAACGTCACCACCGGATCCACACGGGTGAGAAGCCATACCGCTGCAACTACTGCGAGCGCGCCTTCTCGCAGAGCAACGATCTCGTCAAGCACACGCGCGCTCACATCGGACAGAATATATATCAGTGCGCAATATGCGGTTTGCGATTCAGACTCATGTCCGAACTCAAGAGCCACTACCCCATCCACTTCGTTAACGGAAAAATGCAACCCCCAGAGCCCAAGGAAGATGTCAACCTACCAACAAAACCATCATCCCCTACCAAGGACCTCGCCCCACTGCTCGTGCTCAAACCCCCAGAACTACCCCTACTAGCTTTCAATACCAATACAGACATGCCACTAGTTTTAAAGCCTGTAGAAAAAGACATGCCTATTTTGAACCTGAAGCCGACCTCGCCTGTTCAAAATGGCTTGGTGACCAGATCAGAGGTCGGAACAGAAGATGACAAGAACAGGTACACCATTACTATCAATAGTTGTGATAAAAATGGTTTGGTCAATGGTATTACCATAAATATACCGTCTAAAGATACTTAA
Protein Sequence
MLDITSSCRTCMKENVNLIDLYEVVKIEENCHQWADILVICTPTQVSKEDGLPQKLCEECARILQLIYTFRIQAEKAQEEFQKLLQNAIKTEPPEVTPKTENDDNYLHSFDDTDINHDDQKTEDIEENKFTCSKCNKTFLKEKKFLKHLQMHESPLQCTICNKPYHNQASLDKHLAKHNKDYLCLVCNMNFQTESQLFEHSTTEHNKIKIKLENEAQETLLQCPDCDLTFTKQRSLSMHRRRHKNKNNEFICDTCGKTFSMKHQLKRHVVLHSDVKPHVCTKCSKSYARKDQLVHHMHSHKDSKPYECSYCKKGFTQLCSLKDHIRSHTGETPFLCSECGKGFTNSSNLRQHMMRHTGLKPYACNMCPKTFCTKGQMTSHMSTHTGEHPYKCEECGAAFTKQNSLKKHSLIHLGIKPFACETCNMRFTCKDHLKRHHRIHTGEKPYRCNYCERAFSQSNDLVKHTRAHIGQNIYQCAICGLRFRLMSELKSHYPIHFVNGKMQPPEPKEDVNLPTKPSSPTKDLAPLLVLKPPELPLLAFNTNTDMPLVLKPVEKDMPILNLKPTSPVQNGLVTRSEVGTEDDKNRYTITINSCDKNGLVNGITINIPSKDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00707189;
90% Identity
iTF_00441768; iTF_01360908;
80% Identity
-