Hcun017771.1
Basic Information
- Insect
- Hyphantria cunea
- Gene Symbol
- znf423
- Assembly
- GCA_003709505.1
- Location
- PKRV01000669.1:587855-595135[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.66 41 5.0 0.8 1 23 20 44 20 44 0.93 2 20 1.4 89 3.9 6.1 1 23 65 87 65 87 0.96 3 20 0.0016 0.1 13.2 0.1 1 19 110 128 110 130 0.97 4 20 0.17 10 6.8 1.0 5 23 140 159 129 159 0.86 5 20 0.085 5.3 7.8 0.5 1 23 219 242 219 242 0.97 6 20 6.2e-06 0.00039 20.8 0.9 1 23 248 270 248 270 0.96 7 20 0.011 0.7 10.5 3.4 1 23 276 298 276 298 0.97 8 20 1.4e-08 8.4e-07 29.2 0.9 1 23 304 326 304 326 0.99 9 20 1.2e-06 7.7e-05 23.0 1.6 1 23 332 354 332 354 0.98 10 20 0.00026 0.016 15.7 3.3 1 23 360 383 360 383 0.97 11 20 4.6e-06 0.00029 21.2 3.2 1 23 389 412 389 412 0.97 12 20 2.9e-05 0.0018 18.7 0.6 1 23 419 442 419 442 0.97 13 20 0.029 1.8 9.2 5.9 1 23 448 470 448 470 0.96 14 20 0.75 47 4.8 5.4 1 23 476 499 476 499 0.89 15 20 0.004 0.25 11.9 0.8 2 21 504 523 503 524 0.93 16 20 0.00031 0.019 15.4 0.6 1 23 559 582 559 582 0.95 17 20 2.4e-06 0.00015 22.1 0.6 1 23 587 609 587 609 0.98 18 20 1.1 70 4.2 4.0 2 21 614 633 613 634 0.93 19 20 1e-06 6.2e-05 23.3 2.4 1 23 641 663 641 663 0.97 20 20 0.00026 0.016 15.7 0.1 1 23 670 693 670 693 0.98
Sequence Information
- Coding Sequence
- ATGGATAACATAAATCTAGGTCAAGAGCTGAGGGTCGAAGTAGAAAAATTGGGCTTCCACATATGTCCTGTAAAATCCTGCTCAAAACCTTTCCTAGATGCTAGTTATCTGGCCGACCATGCTAAACACCATGATAAGGTGTTTTATGAtcatatgGCCAGTGCATTTGTGGAAATAGAACGGgcgaaaatatttgaatgtgaCAGTTGCAACAAATGCTtcttaagtaaaaataagttttatttacataagctAAAACATATAAGTCTATCTTAtataaacttaaacagaaatataaaaatcaaaggAAATGGCAAAGTTAAAAAGTATAAGTGCTCTGAATGTGAATACGCGTTTGTAGCCAAGAGTACTCTAGAAGCCCATTCTATTTGCCATCAACCATTTCCCCACGTCTGTCATTGTGGGATTGGCTACTACCAGCTAGAAGACCTAAAGAGTCATAAAAAACTTGTGCACCCTGTACAGAAGTCAGAAAAGTTAAAAGCAGTAAATAACGACATACCtaagttatttaatagtaaGTCTAAGAAGCAAGAGCCTGTTCCTAAATTGAAAGCTGAGCTAAAATTTCGTCAAGCTCATCAAGCAGTTGCACTtccaaaagtaaattttaaacggACCATAAGCGGCAGATACCAGTGCCCACATTGTATGAACGACTTTGCCTCTAAAGTTGGTGCTCAGATCCATTACCGCTCCATACACAAAGGTGAACGGCCACACATCTGTCAAATATGCGGCAAAGGTTTTACTCAGTCTTCTGTGCTTAAAAATCATTATCTTATCCATACTGGATCTAGAGACTATGCATGTCGTTATTGTCAAAAAGCATTTCGGACTTTTCATACTCGAGAACTCCATGAACGAATTCATACTGGAGTGAAACCATATCAATGTACTTACTGTAAGAAAGCTTTCAGCGACCCAAGTGCCTTCCAACGTCACATACGAATACATACTGgagacaaaaaatatgtatgtgctCATTGTCCTAAGACCTTTACCGATAGCAGTGCCCTGTATGTTCATAGAAAAAGACACCGGCATGAAAGGAATCATACTTGTGGGAATTGTGACAAAAAATTCTACACCAAGTCTGACGCACGGCTACACTACAAGACTGTACACAAACCTGAATTGAATTTCCAATGCGATTActgcaaaaaaagtttttcaaccaaaatgtatttatcatCCCATATAAAATTAAGACATTCTAGCAACAACAAGACCTACAATtgtaatttgtgtttaaaaatatttaaacaagaagAGTATCTACAAGTACATATGAAAAGTATTCATGGGGGTCAAAGAAACCACACTTGTAAAGTTTGTTTCAAGCAATTTTTCCATAAATATAGGCTTGAGGAACATATGGTTTTGCATTCGGgtgtaaaaaaatttgaatgtgATTATTGttctaaaagattttatataaaatcgcATATAAGTTGTCATATAATTCGAAAACACTTGAATAATGTGAAGTGTGAAATGTGTAAACGAATGTTTATATCTAAGTTTGACTTTGAACAACATAAATTGAAAATCAGCGATTGTTGTGATATATGTGGACAGACATTCTTCTGTAAAGGTGAGAAGTTAGTTCACCATAACAATGAGCATATCCTccctaaaaaaataagtagttaTGAATGTGATCATTGTGGCAGCATATTTTCAAAACGCTATcagataataaaacatatactcGAGGCGCACAGCACACCAAAATTTGTATGTGATTATTGTGGAAAGCGTTTTGCACTAAAGGATGCAATCAGATCTCATATGCGGaaacatttagattttttaagttgTAATATTTGTTGTAAACACTTTTATTCAACATCAGagttttataatcataaaagaGTGGGATGTACTGTGGAAAGACATTCTTGTGAGATATGCGATAAGTCGTTCACAAAGTTGAGCAGTTTGCgaaaacatctatccatacacATGGAAAATCGTGAAAAATATAAGTGTCCAATATGCCCTACAGAGCTTTATTCCAAAGCCTCTGTAATTAGACATATTAAGATGATGCATAATAAGaagaaattaaagaataaaagaagGTCCGGTAATCACTGA
- Protein Sequence
- MDNINLGQELRVEVEKLGFHICPVKSCSKPFLDASYLADHAKHHDKVFYDHMASAFVEIERAKIFECDSCNKCFLSKNKFYLHKLKHISLSYINLNRNIKIKGNGKVKKYKCSECEYAFVAKSTLEAHSICHQPFPHVCHCGIGYYQLEDLKSHKKLVHPVQKSEKLKAVNNDIPKLFNSKSKKQEPVPKLKAELKFRQAHQAVALPKVNFKRTISGRYQCPHCMNDFASKVGAQIHYRSIHKGERPHICQICGKGFTQSSVLKNHYLIHTGSRDYACRYCQKAFRTFHTRELHERIHTGVKPYQCTYCKKAFSDPSAFQRHIRIHTGDKKYVCAHCPKTFTDSSALYVHRKRHRHERNHTCGNCDKKFYTKSDARLHYKTVHKPELNFQCDYCKKSFSTKMYLSSHIKLRHSSNNKTYNCNLCLKIFKQEEYLQVHMKSIHGGQRNHTCKVCFKQFFHKYRLEEHMVLHSGVKKFECDYCSKRFYIKSHISCHIIRKHLNNVKCEMCKRMFISKFDFEQHKLKISDCCDICGQTFFCKGEKLVHHNNEHILPKKISSYECDHCGSIFSKRYQIIKHILEAHSTPKFVCDYCGKRFALKDAIRSHMRKHLDFLSCNICCKHFYSTSEFYNHKRVGCTVERHSCEICDKSFTKLSSLRKHLSIHMENREKYKCPICPTELYSKASVIRHIKMMHNKKKLKNKRRSGNH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -