Basic Information

Gene Symbol
ovo
Assembly
GCA_030762935.1
Location
CM060884.1:33502467-33511719[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0016 0.67 13.2 4.3 1 21 648 668 648 670 0.94
2 4 8.2e-06 0.0035 20.4 2.1 1 23 676 698 676 698 0.96
3 4 0.0033 1.4 12.2 6.1 1 20 704 723 704 727 0.89
4 4 1.6 6.9e+02 3.7 0.4 1 11 743 753 743 766 0.82

Sequence Information

Coding Sequence
ATGTTGTTGCTTTCAGAACGGAAACAACCAACAGAGGAGGAGAAGGCGAAGACTCCAGAAACGAAGCCAGGACCACGTTTCATCTCGTCCATACTGGGTGGTGACGTTCCTTACCGTGGACACATTCCTACAAGAGCTGAACGCAAGGAATACGCTGAACCGCCGCCACCCccacctccaccgccaccacAACCTCCACGCTGTCAGCAAGTGTCGGTGATCCAGCGTACACCCGCAGCCACGGTTCCAAAACCTCCACCCCCGCCAGATTCGCCGTCACCCCCACCGCCACCAGAACGTGAACCAGAGCAGGACGCGCCCATAGATTACCACGTACCTAAGAAACGAACGGAAAACGACAACGAATCAACAGGCAAACGAATACCTATGGCCTGTCTTCAACGACCCCGACTACCTGGACCTTTACCTCCGCTTGCTAGGCTTGGAGGCGGCAAGCCAAGATCAGTAGCTGCAGGACATGGTCATAGCAATCGTGGCGGCAGCGGGGGTGGTGGTCATCAAGGTGGAGGCGGCTCACATAGCTCCGGTTCCATGTCACAAGGATCctatggtggtggaggtggtctTTCttcaggaggaggaggaggtggaggtttAATGGGAAGTGGGGGAGGAGGTGGATCAATGAACCCTGGAGGCGGCGGAGGCGGGGGTCGTGGGGGAGGAGGTGGTGGCAACTATGGACCTAGCAGTCCTCCCACTGGCTCCCTGCCTCCGTTTTATGAATCACTAAAGGGTGGAGGGTTGGTAGGAACTTTGGGAGGTGGAGTGTTTAATGGGGGACTTCAATATCCAGGAGGAGTGGGCAATTATGGGATGTTATCAGCCCCACTGCCTATGGACTGTGACACAGGTCAGGGGCAGGAATCAGGGGCATTGGGCTATTCAAAACAATACTCATTACTGCAGAATGTGGGGGCATCTTATGGTCTCATTACAAtaaaagaagatgaagatgatgacaCCATTCTGGGTTCTGGGAATAATTATACGCAATATGAAGACTCTATGTTAGTGGATCTTGCAGCAGCTAGTGGAGCTGTGGTGGATCCCCTACAGTTTACAGCCACTCTCACATTCTCAAGCCCAGCTGACCACAATGCTTTGTTGGAGAGCCTCTCTGATGACCTGTTTCTGCAGCGCATGTCATCTGCCTCACCAGATGATGCTTCTGATCTGTTGACTCCAGAACCACAACCACAGACTAACATCCCAGGTCCAATTGAACCTTCAGTGGATCCCTTCCCAGAGCACAATGCCCTCGGCCTGAATCAAAGAAGCAGTTACAATGACACATCCCGCAACTTTGCTGCTCCAACACACTTCACCAAGAACACACTTTTCCTCAATGGTAACAGCAATAACCATAACAGCAGCACAACCGAAGGAAGCTTTCACAACCTGCCCAAGGAGAGACCTGAACTTGCCCTGCATATCTCTTCTAGTGGAAACAGCCAATCAGAATCAATGCAGCAACTGCAGGTTCAGGTGCAGCAAACGCAACAAAACAGTGGCCTGCTCTCTCCAGGATTAAGCTTTGCAGACTTGGACTCGCCCACTACTATGTCGCTGCCTTCCCCAGGATGCAGTCTGGATGGTACAACAAGTTCTCTATCTCCACCGGCCAGTATCAGTGGACGCAGAGACTCAACAGCTGCCTCAGCTTCAGCAGCAGCTGCAGCTGCAACAGACATTGCCAGCATACCATCTCTTCAGGTCCGTGTGAACATCCTGCAGCAGAGGCTTGGTTTGCCTGGAGATATGCAAGTGGAGTTTGTAAATGGCGGCCATGGGATCAAGAATCCATTAGCTTCCCATGAGACCATCCCCCGTGGTGGAAGCAGTTCAAGTAGCAGCAATGGAGCTGATTCTGACAGTAAACCAAACCAGCAACAGGTTAACCCTGATGATCCAGCAAGATTTGCATGCAGGATGTGTTCCAAGTCTTTCAGCCTGCAACGCCTTCTTAACCGACATATGAAGTGTCATAGTGACATTAAACGATATCTTTGCACATTCTGTGGCAAAGGATTTAATGACACCTTTGACCTGAAACGACACACTCGTACACACACAGGTGTACGACCATACAAATGTAATCTGTGTGAGAAGTCCTTCACTCAGCGCTGTTCTCTAGAGTCCCATTGTCTCAAAGTGCATGGAGTTCAGCATCAATATGCATATAAGGAACGTCGTACCAAGatGTACGTCTGTGAAGAATGTGGGCATACCACGAATGAACCTGAGGTGCACTATATTCATCTGAAGGAGAATCATCCTTACAGTCCTGCATTACTGAAGTTCTATGACAAGCGGCATTTTAAGTTTACCAATTCCAATTTTGCAAACATGCTTTTGCAAGTGAGATCCTGA
Protein Sequence
MLLLSERKQPTEEEKAKTPETKPGPRFISSILGGDVPYRGHIPTRAERKEYAEPPPPPPPPPPQPPRCQQVSVIQRTPAATVPKPPPPPDSPSPPPPPEREPEQDAPIDYHVPKKRTENDNESTGKRIPMACLQRPRLPGPLPPLARLGGGKPRSVAAGHGHSNRGGSGGGGHQGGGGSHSSGSMSQGSYGGGGGLSSGGGGGGGLMGSGGGGGSMNPGGGGGGGRGGGGGGNYGPSSPPTGSLPPFYESLKGGGLVGTLGGGVFNGGLQYPGGVGNYGMLSAPLPMDCDTGQGQESGALGYSKQYSLLQNVGASYGLITIKEDEDDDTILGSGNNYTQYEDSMLVDLAAASGAVVDPLQFTATLTFSSPADHNALLESLSDDLFLQRMSSASPDDASDLLTPEPQPQTNIPGPIEPSVDPFPEHNALGLNQRSSYNDTSRNFAAPTHFTKNTLFLNGNSNNHNSSTTEGSFHNLPKERPELALHISSSGNSQSESMQQLQVQVQQTQQNSGLLSPGLSFADLDSPTTMSLPSPGCSLDGTTSSLSPPASISGRRDSTAASASAAAAAATDIASIPSLQVRVNILQQRLGLPGDMQVEFVNGGHGIKNPLASHETIPRGGSSSSSSNGADSDSKPNQQQVNPDDPARFACRMCSKSFSLQRLLNRHMKCHSDIKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNLCEKSFTQRCSLESHCLKVHGVQHQYAYKERRTKMYVCEECGHTTNEPEVHYIHLKENHPYSPALLKFYDKRHFKFTNSNFANMLLQVRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00995904;
90% Identity
iTF_01411129;
80% Identity
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