Basic Information

Gene Symbol
-
Assembly
GCA_030762935.1
Location
CM060880.1:3657103-3725329[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.53 2.2e+02 5.2 0.1 6 23 458 475 458 475 0.91
2 15 0.00015 0.063 16.4 0.2 2 23 480 501 479 501 0.98
3 15 9.9e-06 0.0043 20.1 0.9 1 23 509 531 509 531 0.98
4 15 0.00069 0.3 14.3 0.7 1 23 540 563 540 563 0.95
5 15 1.6e-05 0.0067 19.5 1.1 3 23 571 591 570 591 0.97
6 15 3e-05 0.013 18.6 0.8 2 23 599 620 599 620 0.97
7 15 0.14 58 7.1 6.6 1 21 626 646 626 648 0.95
8 15 0.00016 0.07 16.3 1.7 1 23 654 676 654 676 0.97
9 15 1.9e-05 0.0083 19.2 2.9 1 23 682 705 682 705 0.97
10 15 7.4e-05 0.032 17.3 0.6 2 23 1219 1240 1218 1240 0.97
11 15 0.00011 0.046 16.8 0.8 1 23 1248 1270 1248 1270 0.99
12 15 0.029 13 9.2 2.3 1 23 1279 1302 1279 1302 0.92
13 15 0.00075 0.32 14.2 6.4 3 23 1310 1330 1309 1330 0.97
14 15 7.6e-05 0.033 17.3 0.8 2 23 1339 1360 1338 1360 0.98
15 15 0.36 1.5e+02 5.7 2.7 1 16 1391 1406 1391 1408 0.88

Sequence Information

Coding Sequence
ATGCCTACCTGTTGTGAAACACTCTTCTTCAGTAAGAACCGTGGCTCTCTCCTAGACAGCCCCGATCTTTCAAGTGACCCCCTGAAAGTGGAGTCTGATTCTCATATTGCTGATAATGATAGGACAGCTCTTGTTGCAACAGAAAATAGGAAACCAGTTCCATATGGCGTCTTACAGACGTGCGCTAACAATGCACACTCAGCCCTCAGCGCAGCAGAAAATAGGAAACCAGTTGCATACGGCATCCTACAAACGCAGCCAAACAATCCAAACCCTGTGATGTCGTTACTCATAATGGGTGATGATTCAGCGAACAACCCAAGTGTGCAGCCGCAGTTACTTAACTCAAATCCAATGTTGCCATTTATGGTGAGCGATAACAAAGATGTTCAAAATAATGCAAATGTTGTTAATCCAAATCCATTGATGCCATTGCTGTTACCGGGCAGTAATACAGGACTTCAGAGTGTGACAGATGTACAAACCCAACTGCCATTGATAGTAACAGGTGGTAACATTGCTGTACAAAACAATAAAGCGAATAGTGCAAATGTACAAACTCCAATTATGAATCACGGTTCAATACTGCCATTTCTATTAAAAAGTAGTAATACGGGTGTTAAAAACAGTAAAGTGAATACTGAAACACAGTTTTTAAACTCTAATGAGGTGATGCCATTGTTACCGTCgcttcaaaataaaacaaagccaCAAAGGTCACTTCTGAAGCCTAACCCACTTGCATCTTCGTTAGCAGGTGTTCAAAACATTGTGTATAACACAGGTGTACCAACACAGTTTCTAAACACTAATCAGAAGCTGCCGTTGCTACCTCTTAGAAGCAATAAACATAAGAAGGTGAAAAACACAAAACCTCAGATACTACCATTGTTATTAGGAGCTGGTGATTCCAGTGTTCAGAACAACAAAGTGAACCAAATAAGTCCACAAGCGCAGTATTTCGTTCACAATCCAATGCAACCGTGGATGGTTGTTGGCAGTAATCCAAATGTTCAGGATACAAAGATGAATAATACACCAACAGAGTTTGTCAATCCAAATTCAATACCGCAGTTTCTAGTCATTAATGGTGATGCAACCATTGCGAATAATGTGGGGAACCCAGCTGTGCCACTGAATCCTTTGGAGAAGCCCCTGTTGGTGGTCAGTGGTAATTCAGAAGTTCAGAATGAGAAAATAAGCAGCACGAACACTGAGCTTCCTTCAGAAGATTCACGGTCTTCAAGAGAATGTTCATCTCAGAACATGACCGCTACCAATAATGATGCTTCCAAAACTGAGACGCCACCAGAAGATGGTTCCAATAATGCTGAAGGggCAGAACATGGCAACAATGCTGTTGTATCTTGCTGCAACAGGGAACTTGTTGGAGAAGCTAACCTGGTACGACACATGAGGCAACACAGGCAGCGAGTCAAATGTCCAGAATGTGGCAAAGAACTGTCGATGCGCTGGTCCCTCAAGTATCACATGCTGCGACATCTTCCTCAGGAAAGACGACCGTTCAAGTGCAAGAAGTGTGGCAAAGGTTTTGCTATGCAAAGCGAGGTCCAGAAACACCAAACAGTTCATCTCACAGAAAATGAGAGAGGGCGTCATGTCTGTGATATATGTGGCAAAACGCTGAGCACTGCCTACTCTGTATTGAACCACCAGCTGTACTTCCACCAGCGGGTTCAGAAGGCCATGTGTCACATCTGCCCTAAGACGTTCAGCACGGTGTCAGCTCTCAAGATCCACCTCACGTCGCACTACTCTAAGCCTCAGAGCGAGAAGTGTCCGGAGTGTGGCAAGATGTTGAAGAACAAGATGACACTGCGATCTCACATGCTGCTGCACAACAGCAAGAAGACGTACCCGTGTCCACACTGCGACAAGGTGTGCAGGTTCACCAACAGGCTCCGGGAACACCTCCGCTGTCACCAAGACTTGTGGCCTCACCAGTGTACCTTCTGCAAGAAGCTCTTCAAGCGTAAAGCTGGACTCCAGGCACATATTGTGGTCCATACTGGTGAACAGCCATATCAGTGTCCATATTGTTCTCGCACGTTTGCAAGTAAGAGTAATTACTACTCTCATAAACAAAGAATGCATATTAGAAGAAACGCAAATAAGAAACCTGATACTGCAGATAAGAAAACTAAGGTGCCAAAAAGGAAGAAAGGTAACgtgagaaacaaaaagaaaaagaaggtgTCAGATAATGAGGAAAGCAATGATAGTGACAGTGCAACATGCAATAGGCAAGTAGAAGCTGCAGACTGTAATGTTGATGCTAATAGTGGGGCAGGTGATACTGACGTTATAGCAAATGAGAATACTGACAAAGCAGCTGATGGTAATATTCCAGAAGAGGGAGGATCAAAGATGGATGTCTCAGATAATAAGATAGAAGATCTGGGGAAAGGCTTCATCGAGCCTGAGAAGGATCCACTTGACACCAGCGCAAGTGAGGCACAGCTTCAGATTGATCAGAAGCCACAGTTGGTAGTAACTGGTGCCAACATTGCAGCTGTTGACGTTCAAAATAAGAACACTACTTTACAAACACAATGTCAAAATCAAAAGCAGATTCTGACTATCACTTCCAACGCACACACTCAAAATAAACCGAGCGTAAATGTTAAGAACTTCAATCAAACACCGCCATTTTTATTAATCAGTGGTGTTCAGAATAATGCAAATTCACAGCTTCAGAGCTCCAATCAAACACCACCATTGTTTCTGATTAGTGGTGTTCAAAATAACACAAATTCACAAACACAGCTTCAAAACACTAGCCGGATAGTGGCACCGGTTTTAGTTAGTAATTCTGGCGTTCCAAATAGGGTGACCTTAAAAATACCAACACACCTTCTGAACTCCAATAAGACGATACCGTACTTGATTGTTAGTGGCAATTCACTTGTTCAAAGCAAGGGGACTGCAAATAAACCAACCCAACCACACATCCTGCCAAAACCGTTCTTTGTCACTAATAACTCAAATGTTCAAAATCAGGTAAAAAGTTCAACTGTACAAACACAGTTTCAAAATACAAATCAGGCAGCACAGTTGGTAGTTGTGGGTGCTCAAAACAAGGTTAACAACCTGCAAACTCAGCCGCAGAATCCCAGTCAGATGGTACAGTTACGAATTGTGAATGGCAGTGTAAGTGTTCAGAGCAAGGAAAAGCCTGAAAATGCACTGAAACAAGTTCCGAGAGAGAATCAAAACGAGGCCGCAGCAGAGAGCAGTAAGTCTGATGTCCAGGACAAGAAGGCGAGCAGTGAAAACATGAGACTGTCTGCAGGAGACGGCTCCAGCGAGACAGCACATATGGAAGCAGAGCAACAAGATGACAATTCGGGCACTGATAGTGAAGCAACAGATGATGCCCATGAGAACCTGGATATGTTCACGGATGATGATGAATTCTACGAGTACACTCAAAAAGATGCAGATCTCTCTGCGTTTTATGATTTTACCTGTGCTTTCTGTAAACCTGAAAAGAAGACATTCAAGAAATATGTGTTTCTGGACAGACATTGCCAGTGGGAACACGACAAGAAAGCTGTTATTGAATGCTGTGGAAAGGAACTTTTTGGAGAGTTTCCACTTTTGCAGCACATGAAGAAGCACACTCAGTGTATAAAATGCCCTGTGTGTGATAAACAACTTGCACATCCCAACTCGCTGAAGCTGCACATGATGCGTCATCTTCCAGAAGAAAAGATGCCATACAGGTGTGGAAAATGTGGCAAAGGTTTCTCCGTCAGAATGCGTCTTCAGAACCATGAAAATACTCATCTCTCAGAAAAGGAGAAGTTTGTTCATGTCTGTCAACTTTGTGGGAAAAAGTTCTCCAGCGCACTTGGGAAGCGAAGTCATGAACGGTACTTCCACCAGAAAGTGCAGAACGCCATGTGTCACATCTGCCCAAAGACATTTCCCACTTACTCATGCCTTCGACAGCATCTGCACTCTCATAATACTTTCGAGCGAGAGTGTGTGAAATGTGCAAAGTGTGGCAAGCTGTTGAAGAACAAGGCCACATTGAGAGTCCACATGAAGACGCATGAGATCAAGAAAACATCCCCCTGCCCCTACTGTAAAAAGGATGTGTACAAGCTGCGCTCACATCTCAAGTGTCACCAAGAACAGTACCGCTACGAGTGTGTGGTGTGCAAGAAGAGGTTCAAACGCAGCTGTGGATTCAAGATATCCTCCACCCTACCTGTCCCTAGTTTCCCACCAGAACCACCCACTGAGTCAATTCCCATGTTGCAGATATCCTCCACCCTACCTGTCCCTAGTTTCCCACCAGAACAACATCAATAA
Protein Sequence
MPTCCETLFFSKNRGSLLDSPDLSSDPLKVESDSHIADNDRTALVATENRKPVPYGVLQTCANNAHSALSAAENRKPVAYGILQTQPNNPNPVMSLLIMGDDSANNPSVQPQLLNSNPMLPFMVSDNKDVQNNANVVNPNPLMPLLLPGSNTGLQSVTDVQTQLPLIVTGGNIAVQNNKANSANVQTPIMNHGSILPFLLKSSNTGVKNSKVNTETQFLNSNEVMPLLPSLQNKTKPQRSLLKPNPLASSLAGVQNIVYNTGVPTQFLNTNQKLPLLPLRSNKHKKVKNTKPQILPLLLGAGDSSVQNNKVNQISPQAQYFVHNPMQPWMVVGSNPNVQDTKMNNTPTEFVNPNSIPQFLVINGDATIANNVGNPAVPLNPLEKPLLVVSGNSEVQNEKISSTNTELPSEDSRSSRECSSQNMTATNNDASKTETPPEDGSNNAEGAEHGNNAVVSCCNRELVGEANLVRHMRQHRQRVKCPECGKELSMRWSLKYHMLRHLPQERRPFKCKKCGKGFAMQSEVQKHQTVHLTENERGRHVCDICGKTLSTAYSVLNHQLYFHQRVQKAMCHICPKTFSTVSALKIHLTSHYSKPQSEKCPECGKMLKNKMTLRSHMLLHNSKKTYPCPHCDKVCRFTNRLREHLRCHQDLWPHQCTFCKKLFKRKAGLQAHIVVHTGEQPYQCPYCSRTFASKSNYYSHKQRMHIRRNANKKPDTADKKTKVPKRKKGNVRNKKKKKVSDNEESNDSDSATCNRQVEAADCNVDANSGAGDTDVIANENTDKAADGNIPEEGGSKMDVSDNKIEDLGKGFIEPEKDPLDTSASEAQLQIDQKPQLVVTGANIAAVDVQNKNTTLQTQCQNQKQILTITSNAHTQNKPSVNVKNFNQTPPFLLISGVQNNANSQLQSSNQTPPLFLISGVQNNTNSQTQLQNTSRIVAPVLVSNSGVPNRVTLKIPTHLLNSNKTIPYLIVSGNSLVQSKGTANKPTQPHILPKPFFVTNNSNVQNQVKSSTVQTQFQNTNQAAQLVVVGAQNKVNNLQTQPQNPSQMVQLRIVNGSVSVQSKEKPENALKQVPRENQNEAAAESSKSDVQDKKASSENMRLSAGDGSSETAHMEAEQQDDNSGTDSEATDDAHENLDMFTDDDEFYEYTQKDADLSAFYDFTCAFCKPEKKTFKKYVFLDRHCQWEHDKKAVIECCGKELFGEFPLLQHMKKHTQCIKCPVCDKQLAHPNSLKLHMMRHLPEEKMPYRCGKCGKGFSVRMRLQNHENTHLSEKEKFVHVCQLCGKKFSSALGKRSHERYFHQKVQNAMCHICPKTFPTYSCLRQHLHSHNTFERECVKCAKCGKLLKNKATLRVHMKTHEIKKTSPCPYCKKDVYKLRSHLKCHQEQYRYECVVCKKRFKRSCGFKISSTLPVPSFPPEPPTESIPMLQISSTLPVPSFPPEQHQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-