Basic Information

Insect: Hymenopus coronatus
Gene Symbol: ZNF648
Assembly: GCA_030762935.1
Location: CM060890.1:48336096-48393062[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 1.7e-06 0.00074 22.5 0.5 3 23 663 683 662 683 0.99

2 10 5.1e-05 0.022 17.9 1.9 1 23 689 711 689 711 0.98

3 10 6.9e-07 0.00029 23.7 0.5 1 23 719 741 719 741 0.96

4 10 2.1e-05 0.0088 19.1 2.7 1 23 747 769 747 769 0.98

5 10 2.6e-06 0.0011 21.9 0.3 2 23 778 799 778 799 0.98

6 10 2.5e-05 0.011 18.9 0.3 3 23 807 827 805 827 0.97

7 10 3.8e-06 0.0016 21.4 5.4 1 23 833 855 833 855 0.97

8 10 4.5e-07 0.00019 24.3 0.2 1 23 861 883 861 883 0.97

9 10 0.00022 0.096 15.8 7.2 1 23 889 911 889 911 0.98

10 10 3.5e-05 0.015 18.4 2.0 1 21 917 937 917 938 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	1.7e-06	0.00074	22.5	0.5	3	23	663	683	662	683	0.99
2	10	5.1e-05	0.022	17.9	1.9	1	23	689	711	689	711	0.98
3	10	6.9e-07	0.00029	23.7	0.5	1	23	719	741	719	741	0.96
4	10	2.1e-05	0.0088	19.1	2.7	1	23	747	769	747	769	0.98
5	10	2.6e-06	0.0011	21.9	0.3	2	23	778	799	778	799	0.98
6	10	2.5e-05	0.011	18.9	0.3	3	23	807	827	805	827	0.97
7	10	3.8e-06	0.0016	21.4	5.4	1	23	833	855	833	855	0.97
8	10	4.5e-07	0.00019	24.3	0.2	1	23	861	883	861	883	0.97
9	10	0.00022	0.096	15.8	7.2	1	23	889	911	889	911	0.98
10	10	3.5e-05	0.015	18.4	2.0	1	21	917	937	917	938	0.95

Sequence Information

Coding Sequence: ATGATTGGTGAGaaacTACTGCTGGAGCACGGAACTTCAGACCACGTGACAATCATTCTGCCCGATGTGGATCCCGAGGACATGCACTGGCTGCTCCACTTCATATACACCGGCACAGTAGCTGTACCACGCAGTCGACTCAGCTCCTTTTTGCAGGCTGCCGATTCTCTCGGGGTCAAGATGCTCGCTGACATACAGTCTCAAGACAAATGCGATGCCGATAGCGTGATCTGTTGCGTCGATCTCAAGCGTGACGATTTCAAATTCGCAAAAGACAAACGGACTTACACTTCGGAAAATATACGCTCCCAATTGCTTGAAGATGTTTATGAAAATAAAGTAGAGACTAAAGACCACGTATCAGGGAAACACACTGAGCCGAATGTCCAACAAACAGATGCAAAAAAGGAAGAACTACGAACCAGATCGCTGTGCGATTCCGTTGAACCTGTGAAACGTAGTAGTGCTATCGAATCGTTTCAGAAGTGCGAAAGTATGAAGTCTCTTGCCGTTGCAAGTAAACCGCCAGACAGTGCCATCTGCTTTAACCCAACATACTGCGGTGGTCGACAAAAAGACTGTTGCGACGCTAGAACTGATATTAATCCCCAGGCTGCGCCTATTAAGCTTATGTCACCTGTACAAAACAGCTCAATGCCATGCTGTCCTAGAAATGCCCTCGACTATACAGACCCAGCAGTACAGCGGAAAGATGGAGGTCCTGGAACCAAAAGTCCAACTATTAACCCACAAGTTAATACCTACAACGGAATGCTGCCACAGTGTGCAGTCCGCCCCTTTGTAAACGATAAATGTCAGCAGAAACAGCACAGAGACGAAATTCTAACTCATTCCAGGAATATTTATGCAGATATTCATCAATCTGAACACTATTCTCTGCAGCACTTGGCTCAATGGGCAAAACCAGTTCCCTCTCTAATGCCCCTTGCAAACAACAATTATAATTTCAATGGGAAATTTCCTAACGTCCCTCCGTCACCTGCTCTATTTCCTGGAGGAGAACGTCCGCTCAACGGGTACGTGATGAGACCCAACCTAGGAGATTACGGCAAGGACGAAACAATACTACCACCTCCACCGCCTCCACAGTTACCTGGTGATCCCAGATGGGTACATCAGCGCCTTCCAGGACAGATGCCAAGATTATCACCCATTGTGCCGCCTTCTCCTTGGGTACAACACCATCGCCCTCCATGTGCAGCACCCAGAGCATACACCAGTTCCTTACAGCATAGTGGAGGTGCTACTGGAGGTCACCCTGGCCACCGTATTGCCAACACGGCACCCTCTGGACATGCACTGCAACAAGCATTTGGTGATCCCACATTTCATTGCGCAGCCACAGCGATCCACATGaacTCTGCGGAATCCACGGACCCTGCAGAGGGGCACACAACAAAGCTAAGACGCCACGAAGCCAACGAACCAGATACTCGAAAACGAAACCTGGGTAGCACCGAGACTTTACTATGCAGATTAAAGGAAAGGAGACTTCAGGAATTTTACCGTGAACAAAACACCGAAAAAGCTAGAGATTTATCCACCTCAGCAAGCACACCGTTGCCGGCTACAACACAGAAGATGCCTGCCATTCCTCCAGGTTCCTTCCAGCAGAAGCTAAAACACATCGCGGAACTATCCTCTCCGCGACTCCCGGATCACCGGGACAAGCTATTAGCGGTAAAgaaagaagaggaagatgaagGCAGCGATACGAGGAAAGTCTCCACTGACGATGTCGGTAGTTTGAAGACGGAGCCGAATTCCATGAACGACGAGGAGAATAATGATGAGGACGcaagcaacaacagcagcaggtTGACAAATGGGGTCACAGAGGTGGCAAACAACAAGAGGGAAGCTGAGGATGATGAGGTTCAAATCCTTAGTGCTTCCGCCGTACAACCGCCAACATACACCAAGAATGACAACAACAATAACGGAACAGTAACGAAGAACCATGGTTGTGAAGATTGTGGGAAGAGTTTCTCACGCAGGCAGTTGCTGGTGCAACACCGCCGTATCCACACAGGAGAACGTCCATATTCATGCGCCGACTGTGGGCGTCAGTTCACTCAGCGGGGTCACTGGAGCACACATCAAAAGTTACATGAACCGAGCCGGCGACCCGAGCATGCCTGCCCCAGCTGTGGAAAGGCTTTCGTCACAAGAGCTTCCCTTAAGGTCCATCTGAGAACACACACAGGAGAAAAACCATTTCAGTGCACCGAGTGCGGCAAGCAGTTTTCACAACTAAGGAACTACAAGTATCATCGCTCGGTGCACGAAGGCACACGAGAATTCGCCGCTACTTGTCCCGAATGCGGTAAATACTTCAACGATAGAGGATATCTTAGTTCTCACATGAAGATACATCGCAACCGAAAGGAGTACGGATGCCAGTATTGTGGAAAAAGCTTCAATCAACGAGTGGCCTATAACATGCACGTCAGAATACATACAGGTGAACGACCTCATTCCTGCCCACACTGCAGCAAATCCTTCTCCAGGAAAATGTTGCTGAAACAGCATTTACGCATTCACACTGGCGAGAAACCCTTTGCATGTTCCGTCTGTGGGAAGGCATTTGCTGATAGGAGCAACATGACTCTGCATATGCGCCTACACTCGGGAGTGAAACCTTACTCTTGTTCGTTATGCTCCAAGGCCTTCACCAAGAAGCATCACCTCAAGACCCACCTTAACTATCACACTGGAACCAAGCCTTACTCCTGTTCTAAGTGTGGTCTGCGTTTCTCTCAGTCCAGCAACATGAGAACACATTACAAGAAGTGTACTAGTACAGGCCCACCGCAGAATTCATCTCCTGAACATTCCGTGATTGAAAACACACTCACAACTAATCCATCCTTGAAATTGAACGGTGGTTCTCCGGTCGTGTCTCCGGGAACATCTTCCACGGTGGGGTCCGAAGTAGCGGTGTCCTCTCCAAGGTCTGCTTCTGCCTCAGTTATAACACCTCCCCATTCGGATGAATCTTCCTGCGGCAGCTCTGTGATATCCAGAAATGGAATGGACGTGCAAATTGTGTGA
Protein Sequence: MIGEKLLLEHGTSDHVTIILPDVDPEDMHWLLHFIYTGTVAVPRSRLSSFLQAADSLGVKMLADIQSQDKCDADSVICCVDLKRDDFKFAKDKRTYTSENIRSQLLEDVYENKVETKDHVSGKHTEPNVQQTDAKKEELRTRSLCDSVEPVKRSSAIESFQKCESMKSLAVASKPPDSAICFNPTYCGGRQKDCCDARTDINPQAAPIKLMSPVQNSSMPCCPRNALDYTDPAVQRKDGGPGTKSPTINPQVNTYNGMLPQCAVRPFVNDKCQQKQHRDEILTHSRNIYADIHQSEHYSLQHLAQWAKPVPSLMPLANNNYNFNGKFPNVPPSPALFPGGERPLNGYVMRPNLGDYGKDETILPPPPPPQLPGDPRWVHQRLPGQMPRLSPIVPPSPWVQHHRPPCAAPRAYTSSLQHSGGATGGHPGHRIANTAPSGHALQQAFGDPTFHCAATAIHMNSAESTDPAEGHTTKLRRHEANEPDTRKRNLGSTETLLCRLKERRLQEFYREQNTEKARDLSTSASTPLPATTQKMPAIPPGSFQQKLKHIAELSSPRLPDHRDKLLAVKKEEEDEGSDTRKVSTDDVGSLKTEPNSMNDEENNDEDASNNSSRLTNGVTEVANNKREAEDDEVQILSASAVQPPTYTKNDNNNNGTVTKNHGCEDCGKSFSRRQLLVQHRRIHTGERPYSCADCGRQFTQRGHWSTHQKLHEPSRRPEHACPSCGKAFVTRASLKVHLRTHTGEKPFQCTECGKQFSQLRNYKYHRSVHEGTREFAATCPECGKYFNDRGYLSSHMKIHRNRKEYGCQYCGKSFNQRVAYNMHVRIHTGERPHSCPHCSKSFSRKMLLKQHLRIHTGEKPFACSVCGKAFADRSNMTLHMRLHSGVKPYSCSLCSKAFTKKHHLKTHLNYHTGTKPYSCSKCGLRFSQSSNMRTHYKKCTSTGPPQNSSPEHSVIENTLTTNPSLKLNGGSPVVSPGTSSTVGSEVAVSSPRSASASVITPPHSDESSCGSSVISRNGMDVQIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00955759;
90% Identity: iTF_00955759;
80% Identity: iTF_00821131;