Basic Information

Gene Symbol
-
Assembly
GCA_958296145.1
Location
OY282513.1:23226158-23231643[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00042 0.028 15.4 2.0 1 23 204 226 204 226 0.97
2 13 0.00032 0.022 15.7 1.4 1 23 232 255 232 255 0.96
3 13 0.001 0.069 14.2 1.1 3 23 262 285 260 285 0.90
4 13 0.01 0.7 11.0 1.4 2 23 496 517 495 517 0.97
5 13 0.0019 0.13 13.3 4.9 1 23 722 744 722 744 0.98
6 13 8.5e-05 0.0057 17.6 1.3 2 23 751 773 750 773 0.95
7 13 5.7 3.9e+02 2.4 9.4 2 23 779 803 778 803 0.91
8 13 1.8e-05 0.0012 19.7 2.1 1 23 822 844 822 844 0.96
9 13 0.0012 0.079 14.0 3.1 1 23 852 874 852 874 0.98
10 13 0.0081 0.55 11.3 0.9 1 23 879 901 879 901 0.98
11 13 9.6e-05 0.0065 17.4 0.2 1 19 907 925 907 930 0.91
12 13 0.013 0.88 10.7 2.1 1 23 936 958 936 958 0.97
13 13 0.00012 0.0079 17.1 4.6 1 23 964 986 964 987 0.95

Sequence Information

Coding Sequence
ATGGAAAAGTTGCGCTTAACAAATGTCCATGATTTGTGTCGCACATGTCTTCTGGAATTAAAGCATAGACAGAAGTTTCATCTATATTCCATGCATTACCGAATTCGTAGTTGGCTACAAGATGACTCCCTAAACAGTTCTGAGGATACGTATCCACAATTTGTGTGCGGTCGGTGTCTTGATAAATTGGAAGATATTCTTGAATTCCGGCTTATGTATGAGCGTACGATTAATacgtttaataatattttgaagaattctgCTGTTAATGGGCAAATGAAGTCCGAGTCGAATGTTATGGTTAAGGCCAATAATGTCGTGGAGGACGATACAGATGCGGCAGCAGTTCTTAATGAGATACATAGCAATGGAGATTTGTTGGAATTTGATTGTATGCTTATTTCGAACCagcCTGCAACATCCAAGGACCAGCAATTTCttgaaaatgatgaaaccacAACTAGCTTAAATGAAGAATCTACAGATTTCTTCGACTTCATAGAAGCAGACCAAGATATAAGAGTCAATGTGAGTTCCGACGAAGATaaatgcaacaacagcaaactgAAACACTATGAAACCAATGGCGAGAACAgcaacaaacatatatttaattGTGATCAATGTAACAGGCGGTTTGAGAATCAAGGCAAACTTgataaacacaagaaaatccaTCAGGATCTCAGGACATTTCAATGTCCAAAATGTGATCATGGTTTTAATAGACTGAACCGCTtacaaaatcatttaaatgaagtTCATGCTCAAATAAGTATTGACTGTGAATATGAGGGTTGTGATAAAGTGTTCCGGCGCTCTCATACATATATGCGTCATAAACTTTATGAACATGTGGACGGAGGAAGACAAAAAACGACCTCCGATCAACAATACGACATTTGTGATGAATCGGAAAATGTAACAGAGGATATAACAAGTATTAATGAACATCTGTATTGCCGTAAACCGGAAATCAAGAAAGTCGATGAGGAGAATGAGGTAGTTCTGAATGAGACAATCGACGATAGCGATTTGTTGGAATTTGATTTTATACCTATTGACAGAATGACGTTACCCGCAGATTTAATATACTCCGAACTTTCTGAAATGGAAGACTCAAAAATTACTGTGAACATTGGGCAGGCAGATTCTTTTGAGTATCTGGCAAATACCCAAGAAAATATGGCCACTGACAAAGATGAAGACAGCAGAGGCAATTGCAGCATTCATATAAAGGATGAAGATAGTGCAGAGGAAGTGGGCGATGTGGTTTCGTATGATATGTTTAGCGTAGCAAATAACTCCAGCCGTAACCACTGGAAGCAGACATTGGACACTCACAGGAAAACCCATCTAAAGACAAAAGATTGTCCTCCACATGTTCTATCGACTGCAACAAGAATCCCCGTCTGCGATAACGTGTCCGAAACAAACAAGATTCAAAAAGTAACAACTGTTAAAACAATGCAACGATTAACGTTACCTTGTAATCAATGTGATAAAGTTTGTTTCAGTCAAAGAACATGGGACATTCACCAAATGACCCACAAACGACTCAAAACCTATCAATGTCCAAAAAAATCCAATCAAAGTTTTGAACATCTCAATAAAGTGCActccaacaaaaatattatctgCAAATATGAGGGTTGTAATAGAATGTTCCAATGTTCTGATTCATACACCTACTTCTGTCACTGTCGTGATGACCATGGACTGAAGGCGAATAAAGAGGCAACAACAATGTCCCATGAACCTCGAGAACTTTGCGTAAAATTAAGCCGACTTAAAGAACATCAAATGCAAGGAACATTTAAATCGCTAAaggcaaatggaaaaattgtaGAGGACGATACAGGCGTAAACAATGATTTGTTAGAATTCGATTTTACATCTACGGATGGGAAGTCCACAGAAATCTCACAATCTCAACATGATGGAAAAGTGGGACATACAACTACATGTCATAGCGAATACCAAGAAAACAACACCAACGATAACCCTGAAGAGCGTCTAAGTAGAATAAATGAAGAAGAACACAATCCCGAGGAAAACCATCAATGTGCCCCAACAAACACAGCGGCACAAAAGTTATCTAGTACAACGTCAATGAAAATGCCCTTGACTAGCAAAACCACCCCACGGAAGTATGGATATCAATTTCGATGTAATCAATGTAATAAGCGTTGTTTGAATCAGCAAACATTGAATAATCATATGAGAATTCATCAAGGACTTAAACCCTCTCAATGTCCGAAATGCAATCGCAGTTTTCATTCGCCAGCCTATCTGCGAGTTCATCTAaatgaattccacaaaaaaatcaatattaaatgtGAATATGAGGGCTGTGGCAAAGAGTTTCATCGTACTTGTACATATCGCCATCATAAACGTCATAAGCATATGTTCGTTGACCAACCAAAGCCTAAGCCCCCAAAAAATCCTCAACAGGCCCAACACATTTGTGAAGAGTGCGGAAAGGTATATACACAACTACATAGTCTTCAGGCCCATCAATATAGCCATAGGCCTAAAGAGGAATATCCATTTCATTGTTCCCACTGCGATGGTGCTTTCGCATCTCGAGAAAGATTAAAACGTCATCTAATCACACATAGAGAAAAAATCTATGAATGTCCTCATTGTGGCCTAATGAAGAGAAATGTTTACGAATTACGGATGCACATCAACTACCACACCAAGGAACTGAAGTATCCGTGTCCAAAATGTCCCAAGGTCTTCAATGATTCGGTTAATTTAGGCAGACATGATAAGATATCGCATCTGGGTCTGCGACCTTACGCCTGCCGCTACTGCGATCAGAAGTTTGCTGTAAGCCAGACTTGGAAGCATCATGAAATGCGTCATACAGGTGAAAAACCCCATGAATGTCCAGTGTGTGGTCTACGCTTTATACAACCGTGCTCCATGAAGAGGCACATTAAAAGGCACCATAGTGGAAAAAAACCTGCGTCGCCAATTGCTGGTAAACAGAAGAGGAAACGGAAAACGTAG
Protein Sequence
MEKLRLTNVHDLCRTCLLELKHRQKFHLYSMHYRIRSWLQDDSLNSSEDTYPQFVCGRCLDKLEDILEFRLMYERTINTFNNILKNSAVNGQMKSESNVMVKANNVVEDDTDAAAVLNEIHSNGDLLEFDCMLISNQPATSKDQQFLENDETTTSLNEESTDFFDFIEADQDIRVNVSSDEDKCNNSKLKHYETNGENSNKHIFNCDQCNRRFENQGKLDKHKKIHQDLRTFQCPKCDHGFNRLNRLQNHLNEVHAQISIDCEYEGCDKVFRRSHTYMRHKLYEHVDGGRQKTTSDQQYDICDESENVTEDITSINEHLYCRKPEIKKVDEENEVVLNETIDDSDLLEFDFIPIDRMTLPADLIYSELSEMEDSKITVNIGQADSFEYLANTQENMATDKDEDSRGNCSIHIKDEDSAEEVGDVVSYDMFSVANNSSRNHWKQTLDTHRKTHLKTKDCPPHVLSTATRIPVCDNVSETNKIQKVTTVKTMQRLTLPCNQCDKVCFSQRTWDIHQMTHKRLKTYQCPKKSNQSFEHLNKVHSNKNIICKYEGCNRMFQCSDSYTYFCHCRDDHGLKANKEATTMSHEPRELCVKLSRLKEHQMQGTFKSLKANGKIVEDDTGVNNDLLEFDFTSTDGKSTEISQSQHDGKVGHTTTCHSEYQENNTNDNPEERLSRINEEEHNPEENHQCAPTNTAAQKLSSTTSMKMPLTSKTTPRKYGYQFRCNQCNKRCLNQQTLNNHMRIHQGLKPSQCPKCNRSFHSPAYLRVHLNEFHKKINIKCEYEGCGKEFHRTCTYRHHKRHKHMFVDQPKPKPPKNPQQAQHICEECGKVYTQLHSLQAHQYSHRPKEEYPFHCSHCDGAFASRERLKRHLITHREKIYECPHCGLMKRNVYELRMHINYHTKELKYPCPKCPKVFNDSVNLGRHDKISHLGLRPYACRYCDQKFAVSQTWKHHEMRHTGEKPHECPVCGLRFIQPCSMKRHIKRHHSGKKPASPIAGKQKRKRKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-