Basic Information

Insect: Hydropsyche betteni
Gene Symbol: zfh1
Assembly: GCA_028571205.2
Location: JAOXNN020000043.1:2449023-2454822[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0047 6.2 11.4 0.0 1 23 73 95 73 95 0.96

2 8 4.9e-06 0.0065 20.7 0.6 2 23 106 127 105 127 0.96

3 8 1.2e-06 0.0016 22.7 6.2 1 23 136 158 136 158 0.99

4 8 5.7e-05 0.075 17.4 1.1 1 21 164 184 164 185 0.95

5 8 0.00086 1.1 13.7 1.3 2 21 442 461 441 462 0.92

6 8 1.8e-05 0.024 19.0 0.6 1 23 763 785 763 785 0.94

7 8 0.0025 3.3 12.2 5.9 1 23 791 813 791 813 0.97

8 8 0.044 58 8.3 7.1 1 21 819 839 819 840 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0047	6.2	11.4	0.0	1	23	73	95	73	95	0.96
2	8	4.9e-06	0.0065	20.7	0.6	2	23	106	127	105	127	0.96
3	8	1.2e-06	0.0016	22.7	6.2	1	23	136	158	136	158	0.99
4	8	5.7e-05	0.075	17.4	1.1	1	21	164	184	164	185	0.95
5	8	0.00086	1.1	13.7	1.3	2	21	442	461	441	462	0.92
6	8	1.8e-05	0.024	19.0	0.6	1	23	763	785	763	785	0.94
7	8	0.0025	3.3	12.2	5.9	1	23	791	813	791	813	0.97
8	8	0.044	58	8.3	7.1	1	21	819	839	819	840	0.96

Sequence Information

Coding Sequence: AtggtggcgcgcggcgacgccatGTTCGGCTGCTACGGAGACAGCAGCTACTCGTACCGCCTGTGGAGCTTGGCCAACTGGACGGGGGCTCACTTCCCTCCCTTGagcaataatgataataaaagtgTGACTGAAGAAGATGACGTCCCTCCTATTGGAAATGTCAATGCGCGATCTAGGAGATCTCCATCGTTACCCTTGGGACCTGGTGGTCCGTTCACATGTCCTCAATGCGGAGGTGCATATCCTTCAAGAGAACTGCTCGATAAACACGAGTTACTTCACTCGCCTAACACACAGGTGAGAGGCACTATCTCTTGCAAAATTTGCAACAAAAGTTTTGCTAATGTGTATCGCCTCCAAAGACATATGATTAGTCACGATGAAAGCGCATTATTGCGCAAATTTAAGTGTAATGACTGTGATAAAgcctttaaatttaaacatcatttAAAAGAACATCTCAGAATACATAGTGGAGAGAAGCCTTTTGAATGTGGCAACTGCGGGAAAAAGTTTTCCCATTCAGGCTCTTATTCTAGTCATATGACTTCCAAAAAATGCCTTGTTATGAATCTCAAAATGGGTCGCATTCGGCCCAACAACCCTGCGCTTAATCCTGAAAGAAGCCCATCAAGAAAACGGAACGCAACTATCCTACCACAAATCAATAACAATTCgtcttcaaataataataattcgtttttgcCAATGTTACCAAAATACAGTgatgcggctgctgctgctttTTTGGCTTCAATTACGCCTAGAGATGGAGGTTTTCCTACTTCCCCAAGCCCGTTGGCAGCTTCTGCTCTCCATTCATTGTACTTGCCGCATTCTATGCCTCTTCATCATCCGAGCGCAATGACTCCATTCATAAGTAACTTATTTGAGCATCTTACTACTCCTCAATATTTACCTCGCAAGATCGAAAAAGAATATACCAAAGCTTTAAGTCCACAGTCTGATCCTGAAGATATGATTGAAGAAGTTACTGAAGAAGAAGATAAGAGATCGTCTGTAGGTGATGATCAAGAATTGGTAATGGATATTGAAGAAGAAGaggcaattaaaataaaacaagaaaaacaatcTGATGACTATcctcaaacaaataataaaacattgtttcaaaatagaGCTTCTCCTGCATGTGACAACAACAGTTCTGGATTAGGATTAAATATGATCTTGGAATCCGTTCTTTCTAATCAAACATCCGTCACGAAAAAGTTATTGCAGGCGCAGACTAGTAAAcaaacttcaaatgaaaatattgttcctGATATTACAATCAAAGGTGATCCAGATGAGCCTTTAAAATGTTTGCAGTGTCATAAAGTGTTCAATCATAAAACTGAACTAGTTCAACATGAACAAGTTTTATGTGGCAAATTGTTCAGGAAACATGAAGGTCTAGCCGCACAAGTGGCAGAAACATTAGCTTTAAATCGTATGGAAGCTGAACTTCACGCATCTATACATAGTGGCATGAGCGGTAGTGAAGATGATGAATATTCTAAAGAATTAGACGGCAAAACTCCacatgaaaatgaaagaaaagttAGAGTACGTACTGCAATAAGCGATGAACAGCAAGCTATTTTAAAAGACCATTATGCTCGTAACCAAAAACCAAATCgtgaagaattcaaaaaaattgcccAAAGATTAGGATTAGATAACCGTGTTGTCCAAGTTTGGTTCCAAAATAACAGAGCACGTGTACGAAGAATGAatcaaactatttcatattCTGAACAACCCTTAGATTTATCtactaaaaaaacaactcaatcaACTACCTCTAGCCCGTCGATTTCTCCTCATTGTAATATGTCCGCTGTACAATCTGACTCTGGTGAAGAAGCTGTTAACCTGAGTCAAAAATCATCTCGTAGTCCTACGCCATATAGAAACCCATTTCAACCACACTATCAACATTCCAACtgttcttcatcatcattaacCGATTTTCGGCATTCACCATCAccaaatgatatattattaaatgggactaaaaaaaattcctttacTACAAAAAGCACTCCTTTGAACAATTCacaaatttcggaaaaattacCTATGTATGACGCAGAAGATACACCTCATTCACCTGTTATATCTAATGTAGATATAGCTAGAGCGTCAAGTTCTAGTCCGAGTTCAGAAAGAAGATCATGGACTGAAGAATCGCGTATTTCTCAAAATGACACTGATGTAGACAAAACTCTGAAGAAAAATCGACTCAAAAATGTTACAACTAAAGAACCAGAGGGTCAATTTATATGTGATCAATGTGATAAGGCATTTGTGAAACAGAGTTCTTTGGCTCGACATAAATATGAACACTCAGGTCAAAGGCCTTACAAATGCATAGAATGTCCGAGAGCTTTCAAACATAAACATCATCTAGCAGAGCACAAACGACTACACACAGGTGAAAAACCCTTCCAATGttgtaaatgtttgaaaaaattctcacacTCTGGATCATACAGTCAGCATATGAACCACCGTTATTCTTACTGTAAGCCATACcgagaataa
Protein Sequence: MVARGDAMFGCYGDSSYSYRLWSLANWTGAHFPPLSNNDNKSVTEEDDVPPIGNVNARSRRSPSLPLGPGGPFTCPQCGGAYPSRELLDKHELLHSPNTQVRGTISCKICNKSFANVYRLQRHMISHDESALLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECGNCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIRPNNPALNPERSPSRKRNATILPQINNNSSSNNNNSFLPMLPKYSDAAAAAFLASITPRDGGFPTSPSPLAASALHSLYLPHSMPLHHPSAMTPFISNLFEHLTTPQYLPRKIEKEYTKALSPQSDPEDMIEEVTEEEDKRSSVGDDQELVMDIEEEEAIKIKQEKQSDDYPQTNNKTLFQNRASPACDNNSSGLGLNMILESVLSNQTSVTKKLLQAQTSKQTSNENIVPDITIKGDPDEPLKCLQCHKVFNHKTELVQHEQVLCGKLFRKHEGLAAQVAETLALNRMEAELHASIHSGMSGSEDDEYSKELDGKTPHENERKVRVRTAISDEQQAILKDHYARNQKPNREEFKKIAQRLGLDNRVVQVWFQNNRARVRRMNQTISYSEQPLDLSTKKTTQSTTSSPSISPHCNMSAVQSDSGEEAVNLSQKSSRSPTPYRNPFQPHYQHSNCSSSSLTDFRHSPSPNDILLNGTKKNSFTTKSTPLNNSQISEKLPMYDAEDTPHSPVISNVDIARASSSSPSSERRSWTEESRISQNDTDVDKTLKKNRLKNVTTKEPEGQFICDQCDKAFVKQSSLARHKYEHSGQRPYKCIECPRAFKHKHHLAEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00158586;
90% Identity: iTF_00814992;
80% Identity: iTF_00814992;