Basic Information

Gene Symbol
-
Assembly
GCA_028571205.2
Location
JAOXNN020247825.1:6619-7648[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.018 24 9.5 0.4 2 20 100 118 99 121 0.92
2 8 0.09 1.2e+02 7.3 0.2 1 23 125 147 125 147 0.92
3 8 7.2e-06 0.0095 20.2 1.7 1 23 152 175 152 175 0.96
4 8 0.00033 0.44 15.0 1.0 1 23 181 204 181 204 0.92
5 8 4.1e-05 0.054 17.9 0.9 1 23 211 234 211 235 0.97
6 8 1.7e-05 0.023 19.0 2.1 1 23 240 262 240 262 0.98
7 8 8e-07 0.0011 23.2 0.6 1 23 268 290 268 290 0.98
8 8 4.6e-05 0.061 17.7 6.6 1 23 296 318 296 318 0.98

Sequence Information

Coding Sequence
atgtataaagacaATTGCAGCAGTGACTATTCAGATCTGAAATTAGCATTCGTCGTCAAAAACGAATATTTGGTCGACGACAATAATGATTTAGAAGATTTAGAAATTTCTGATTGCGAAAGCGACAAGAAcgtaaaattgaacaattcacTCGattccgaaagtgacaaatccAATTCCAAAACGGAGAAACCCGATGTAAAACTGAAGggaaaaaacgacgaaatacACTACCTCATAAAGTCTCACTCCGAAATCCCCAAAATCTCCATACCTAGTTTAGAGCCATCGAcgttgatttgtcccgtttgtaaagaagaattcaaCTCCCACGCCTTCCTGTTGCAACATTATCCGAACCATTACCCTAGTTATTTGTGCGACATTTGCGGACAAGCACACTTAAACAAAAGCAGCCTTTTGAGGCACGTAGCGATACACACTCTGAAACGGCATCCGTGCAAACTCTGCCAGAAGTCGTACGCGAACTCGAGCGCTTTGAATCAACACGTCAAGCGAACACACGAAGGCAGGGAGTCGTACGCGTGTCAGTTATGTCCCAAACGGTTCTCCAGCTATTCGGCTAGAAACAAACACCGAACCGAAGACCACGGGATACCGGCGAGGACGTACGTCTGCCCGAGCTGCGGGAAAATATTCTTGCGGTCGTCAAGGCTGTCCGTTCATATCAGAAGGGATCATCATaagatcaaaaatttcaaatgcaccGTGTGCGATAATAAGTTTTTTACTAAGTCTGAGTTGAAAGATCACGTTTTGAAGCATACAGGTGAGAAAAACTTCGAATGTAATGTCTGTGGTAAATTGTATGCGAGAAAGAAAACGCTGACGGAGCACATGAAAATCCACTCGAATATCCGAGCGCACAAGTGTGATTATTGTGAAAagacttttattcaaaaatgcacTTTGAAGGGACATCTCAAAACGCATATGCGGACgaataattaa
Protein Sequence
MYKDNCSSDYSDLKLAFVVKNEYLVDDNNDLEDLEISDCESDKNVKLNNSLDSESDKSNSKTEKPDVKLKGKNDEIHYLIKSHSEIPKISIPSLEPSTLICPVCKEEFNSHAFLLQHYPNHYPSYLCDICGQAHLNKSSLLRHVAIHTLKRHPCKLCQKSYANSSALNQHVKRTHEGRESYACQLCPKRFSSYSARNKHRTEDHGIPARTYVCPSCGKIFLRSSRLSVHIRRDHHKIKNFKCTVCDNKFFTKSELKDHVLKHTGEKNFECNVCGKLYARKKTLTEHMKIHSNIRAHKCDYCEKTFIQKCTLKGHLKTHMRTNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-