Hbet012812.1
Basic Information
- Insect
- Hydropsyche betteni
- Gene Symbol
- ZNF526
- Assembly
- GCA_028571205.2
- Location
- JAOXNN020000082.1:2089801-2091905[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 6.4e-05 0.085 17.2 0.6 1 23 11 33 11 33 0.98 2 11 0.0004 0.53 14.7 1.0 1 23 40 62 40 62 0.97 3 11 2.2 2.9e+03 3.0 0.0 2 23 67 88 66 88 0.92 4 11 0.0013 1.7 13.1 2.2 1 23 93 116 93 116 0.98 5 11 3.3e-05 0.044 18.1 1.3 1 23 121 143 121 143 0.98 6 11 6.1e-06 0.0081 20.5 0.8 1 23 149 171 149 171 0.97 7 11 0.013 18 9.9 0.8 1 21 177 197 177 202 0.93 8 11 2e-06 0.0027 22.0 1.3 1 23 210 233 210 233 0.93 9 11 0.069 92 7.7 0.7 1 23 239 262 239 262 0.94 10 11 3.5e-06 0.0046 21.2 1.2 1 23 271 293 271 293 0.98 11 11 1.1e-06 0.0015 22.7 2.0 1 23 299 322 299 322 0.96
Sequence Information
- Coding Sequence
- ATGAACGAAGAGAAATATTTGAACGCCCCGTTCAGATGTGAACTATGCGTGATTCCGTTCCGACGCGAATTCACATTACAAAACCACATGGAAAAACATAGCGAGGACAGAGGCCCGTACGTATGTTCGATTTGCCAACAGAGGTTTGGTAATGAAAGACAGTTCAAAATGCACACTTCTATACATAGCATCCGTTTAGTATGTTACGCATGTGGAGCGCAATTGAGAGATCGAGGTCGACTTGCTGATCATCTAGCGTGGCATGCGGGTCATAAGTATCCGTGCAAAATGTGCAATGCGACTTTCATATGCAGAACTACATTGAATAATCATATAAgagtaaaacataaaaataatgaatataaatgcgAGTTTTGTGGTAGAGTTTTCAAAGTGAAAGAACGATTAAAGGAGCACGAAtcACGTCATTCCAAATCACCAGCGTATTCttgtaatatttgtaataagCAATTTTATAGTGCAGCAAATTTGTCTAATCACAAAGTTACTCATTCAACGATAAGACATTATTATTGTGTtgaatgtgatttatatttcaaatctgcatcaatactgaaaaatcatcttgaaaaatcaagaaaacatATAGACCCTTCTTCattacaATATCCATGCGATCAATGCAATAAACGTTTCCGCACTTCAGACTTATTGACACATCACATAGATGCAACACatttgaaacggaaaaaattcaGTTGTGAAATATGTAGTGCGTCATATGCTAGTCATCaaggtttaaattttcatcgtcgaTTGGCACATCAAGGATTTCGTCTTCCAAAGTCACATACGTGTTCTATATGTGAGAGATCGTTCACTGCAAAAGCTCTTCTCACTAATCACCTGAGAGTACATACGGGAGAAAAACCTTTCGAATGTTCCGAGTGTTTCAGAAAGTTTTCTCAAAAGTCGTCGTTAAGAACTCATATTAAACTGGTGCATCTCAAATTGAAACGTGTTGTTAAGAAAAAGTTGAAGTCAaacaatcaaactaaaattcaaGAAACGGACGAAAATAATGGTGTATGTGTGGACAAAATTgatgtattgaatttgtatcCGGAAGAAGTCAAAAGTTGGGAATGTAAATCGACAGATAATTTACATGTTCAACAAGAAATAATCGAAGATGTTTGTGACATAAGTGTACCGATAAATATAGAACATTCTCTATATGATGCTTCTTGA
- Protein Sequence
- MNEEKYLNAPFRCELCVIPFRREFTLQNHMEKHSEDRGPYVCSICQQRFGNERQFKMHTSIHSIRLVCYACGAQLRDRGRLADHLAWHAGHKYPCKMCNATFICRTTLNNHIRVKHKNNEYKCEFCGRVFKVKERLKEHESRHSKSPAYSCNICNKQFYSAANLSNHKVTHSTIRHYYCVECDLYFKSASILKNHLEKSRKHIDPSSLQYPCDQCNKRFRTSDLLTHHIDATHLKRKKFSCEICSASYASHQGLNFHRRLAHQGFRLPKSHTCSICERSFTAKALLTNHLRVHTGEKPFECSECFRKFSQKSSLRTHIKLVHLKLKRVVKKKLKSNNQTKIQETDENNGVCVDKIDVLNLYPEEVKSWECKSTDNLHVQQEIIEDVCDISVPINIEHSLYDAS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -