Basic Information

Insect: Hycleus phaleratus
Gene Symbol: PRDM5
Assembly: GCA_013841185.1
Location: JACDRP010000065.1:145778-189919[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 51 0.038 2.5 8.2 0.2 3 23 19 40 17 40 0.91

2 51 3e-06 0.0002 21.1 3.9 3 23 46 66 45 66 0.99

3 51 6.8e-05 0.0045 16.9 5.4 1 23 76 99 76 99 0.98

4 51 7.9 5.2e+02 0.9 0.0 1 12 106 117 106 120 0.82

5 51 0.00066 0.044 13.8 2.9 1 23 136 158 136 158 0.97

6 51 3.2e-05 0.0021 17.9 1.2 1 23 163 185 163 185 0.98

7 51 0.00095 0.063 13.3 0.8 1 23 191 214 191 214 0.93

8 51 0.0012 0.077 13.0 1.5 3 23 223 242 221 242 0.95

9 51 0.00081 0.054 13.5 1.8 1 23 255 277 255 277 0.96

10 51 0.023 1.6 8.9 2.6 1 23 283 306 283 306 0.97

11 51 0.0001 0.007 16.3 0.6 2 23 323 344 322 344 0.97

12 51 0.00016 0.011 15.7 0.9 1 21 350 370 350 371 0.94

13 51 0.023 1.5 8.9 3.1 1 23 378 400 378 400 0.98

14 51 0.004 0.27 11.3 1.7 1 23 406 429 406 429 0.95

15 51 0.11 7.7 6.7 0.4 3 23 438 457 437 457 0.98

16 51 0.0039 0.26 11.3 3.4 3 23 469 490 467 490 0.96

17 51 0.58 39 4.5 0.3 1 16 497 512 497 513 0.86

18 51 0.092 6.1 7.0 5.4 1 23 512 534 512 534 0.98

19 51 4.6e-05 0.0031 17.4 0.2 1 23 540 563 540 563 0.94

20 51 3.4e-05 0.0023 17.8 2.4 3 23 569 589 567 589 0.96

21 51 8.2e-06 0.00055 19.8 4.7 1 23 599 622 599 622 0.98

22 51 0.0025 0.17 11.9 0.1 1 23 629 651 629 651 0.97

23 51 2.4e-07 1.6e-05 24.6 1.6 2 23 658 679 658 679 0.98

24 51 7.2e-08 4.8e-06 26.2 0.8 1 23 685 707 685 707 0.98

25 51 0.024 1.6 8.8 0.6 2 23 722 744 721 744 0.95

26 51 2e-05 0.0013 18.6 4.8 1 23 750 772 750 772 0.98

27 51 0.00044 0.03 14.3 4.1 1 23 778 800 778 800 0.98

28 51 3.2e-06 0.00021 21.1 0.6 1 23 806 829 806 829 0.97

29 51 2.2e-05 0.0015 18.4 1.9 3 23 835 855 834 855 0.99

30 51 7.3e-05 0.0049 16.8 5.6 1 23 865 888 865 888 0.98

31 51 3.3e-05 0.0022 17.9 1.9 2 23 910 932 909 932 0.97

32 51 9.5 6.3e+02 0.7 0.7 12 23 977 988 976 988 0.91

33 51 0.00028 0.019 14.9 0.4 1 23 994 1017 994 1017 0.93

34 51 2e-05 0.0013 18.5 3.4 3 23 1023 1043 1021 1043 0.96

35 51 6.3e-06 0.00042 20.1 5.5 1 23 1053 1076 1053 1076 0.98

36 51 0.0077 0.51 10.4 0.2 1 23 1083 1105 1083 1105 0.95

37 51 0.12 8.2 6.6 0.3 3 16 1113 1126 1111 1128 0.88

38 51 6e-05 0.004 17.0 2.0 2 23 1135 1156 1134 1156 0.95

39 51 1.5e-06 9.9e-05 22.1 2.0 1 23 1162 1184 1162 1184 0.97

40 51 0.014 0.96 9.5 2.0 1 23 1190 1212 1190 1212 0.99

41 51 0.0019 0.13 12.3 0.2 3 23 1220 1241 1219 1241 0.93

42 51 0.01 0.7 10.0 4.2 3 23 1248 1268 1247 1268 0.97

43 51 1.7e-05 0.0011 18.8 4.1 1 23 1278 1301 1278 1301 0.97

44 51 0.00074 0.049 13.6 1.0 1 23 1308 1330 1308 1330 0.98

45 51 0.49 33 4.7 0.6 2 23 1348 1368 1347 1368 0.95

46 51 0.0012 0.077 13.0 1.4 2 23 1375 1397 1375 1397 0.96

47 51 0.0069 0.46 10.6 5.3 1 23 1402 1424 1402 1424 0.97

48 51 0.0046 0.3 11.1 0.7 2 23 1431 1453 1430 1453 0.94

49 51 2.8e-06 0.00019 21.2 0.6 1 23 1458 1480 1458 1480 0.98

50 51 3.6 2.4e+02 2.0 0.8 2 22 1488 1505 1487 1507 0.72

51 51 0.25 17 5.6 0.7 3 20 1531 1545 1530 1549 0.73

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	51	0.038	2.5	8.2	0.2	3	23	19	40	17	40	0.91
2	51	3e-06	0.0002	21.1	3.9	3	23	46	66	45	66	0.99
3	51	6.8e-05	0.0045	16.9	5.4	1	23	76	99	76	99	0.98
4	51	7.9	5.2e+02	0.9	0.0	1	12	106	117	106	120	0.82
5	51	0.00066	0.044	13.8	2.9	1	23	136	158	136	158	0.97
6	51	3.2e-05	0.0021	17.9	1.2	1	23	163	185	163	185	0.98
7	51	0.00095	0.063	13.3	0.8	1	23	191	214	191	214	0.93
8	51	0.0012	0.077	13.0	1.5	3	23	223	242	221	242	0.95
9	51	0.00081	0.054	13.5	1.8	1	23	255	277	255	277	0.96
10	51	0.023	1.6	8.9	2.6	1	23	283	306	283	306	0.97
11	51	0.0001	0.007	16.3	0.6	2	23	323	344	322	344	0.97
12	51	0.00016	0.011	15.7	0.9	1	21	350	370	350	371	0.94
13	51	0.023	1.5	8.9	3.1	1	23	378	400	378	400	0.98
14	51	0.004	0.27	11.3	1.7	1	23	406	429	406	429	0.95
15	51	0.11	7.7	6.7	0.4	3	23	438	457	437	457	0.98
16	51	0.0039	0.26	11.3	3.4	3	23	469	490	467	490	0.96
17	51	0.58	39	4.5	0.3	1	16	497	512	497	513	0.86
18	51	0.092	6.1	7.0	5.4	1	23	512	534	512	534	0.98
19	51	4.6e-05	0.0031	17.4	0.2	1	23	540	563	540	563	0.94
20	51	3.4e-05	0.0023	17.8	2.4	3	23	569	589	567	589	0.96
21	51	8.2e-06	0.00055	19.8	4.7	1	23	599	622	599	622	0.98
22	51	0.0025	0.17	11.9	0.1	1	23	629	651	629	651	0.97
23	51	2.4e-07	1.6e-05	24.6	1.6	2	23	658	679	658	679	0.98
24	51	7.2e-08	4.8e-06	26.2	0.8	1	23	685	707	685	707	0.98
25	51	0.024	1.6	8.8	0.6	2	23	722	744	721	744	0.95
26	51	2e-05	0.0013	18.6	4.8	1	23	750	772	750	772	0.98
27	51	0.00044	0.03	14.3	4.1	1	23	778	800	778	800	0.98
28	51	3.2e-06	0.00021	21.1	0.6	1	23	806	829	806	829	0.97
29	51	2.2e-05	0.0015	18.4	1.9	3	23	835	855	834	855	0.99
30	51	7.3e-05	0.0049	16.8	5.6	1	23	865	888	865	888	0.98
31	51	3.3e-05	0.0022	17.9	1.9	2	23	910	932	909	932	0.97
32	51	9.5	6.3e+02	0.7	0.7	12	23	977	988	976	988	0.91
33	51	0.00028	0.019	14.9	0.4	1	23	994	1017	994	1017	0.93
34	51	2e-05	0.0013	18.5	3.4	3	23	1023	1043	1021	1043	0.96
35	51	6.3e-06	0.00042	20.1	5.5	1	23	1053	1076	1053	1076	0.98
36	51	0.0077	0.51	10.4	0.2	1	23	1083	1105	1083	1105	0.95
37	51	0.12	8.2	6.6	0.3	3	16	1113	1126	1111	1128	0.88
38	51	6e-05	0.004	17.0	2.0	2	23	1135	1156	1134	1156	0.95
39	51	1.5e-06	9.9e-05	22.1	2.0	1	23	1162	1184	1162	1184	0.97
40	51	0.014	0.96	9.5	2.0	1	23	1190	1212	1190	1212	0.99
41	51	0.0019	0.13	12.3	0.2	3	23	1220	1241	1219	1241	0.93
42	51	0.01	0.7	10.0	4.2	3	23	1248	1268	1247	1268	0.97
43	51	1.7e-05	0.0011	18.8	4.1	1	23	1278	1301	1278	1301	0.97
44	51	0.00074	0.049	13.6	1.0	1	23	1308	1330	1308	1330	0.98
45	51	0.49	33	4.7	0.6	2	23	1348	1368	1347	1368	0.95
46	51	0.0012	0.077	13.0	1.4	2	23	1375	1397	1375	1397	0.96
47	51	0.0069	0.46	10.6	5.3	1	23	1402	1424	1402	1424	0.97
48	51	0.0046	0.3	11.1	0.7	2	23	1431	1453	1430	1453	0.94
49	51	2.8e-06	0.00019	21.2	0.6	1	23	1458	1480	1458	1480	0.98
50	51	3.6	2.4e+02	2.0	0.8	2	22	1488	1505	1487	1507	0.72
51	51	0.25	17	5.6	0.7	3	20	1531	1545	1530	1549	0.73

Sequence Information

Coding Sequence: ATGGATGGACTTAAGCGCCATTTGAAACGGCACACGGAAAATTTTACGATTATTTGTGAACTGTGCGGTAGACGTTTTCTAACGAACGGTGAATATAAACAACACAAAAACGATATACATGACAGAGCTAATCTTTGTAATGTTTGTGGCCGGTCGTTTTGTAGTAAAGAAAGTTTGAAGAATCACATGAAACGACATGATGAAAATTACACAAAAGTACACAATTTCCAATGTGATTTCTGCAGTAAACGATTTAGACAAGACATGCATTTGAAAAAACACATAAGACGCATGCATAATGAGAATCGACGAAAATATATTTGTGATTTATGCAATAAAGAGTTGGCTAGTCAGACTGGAAACGAGTGTCCAGAAGCCCAGGATCTTCTAATACAATTTCAACTTTATTCGTGTAATATCTGCCAGAAAACTTTCAAAGGCAAACGAACGCTATATTACCACAAATCTGTTCATAGTAACGTAAAATATGAGTGCAACATCTGCGGTAAAAAGCTCAAAAGTTTCAGTATGTTGAAGATTCATCGTTTACGCCACTTGAAACAATATAAATACACGTGTGAAATTTGTGGTTACGGTTGCATGTTTAACAGTGAACTGAAATCGCATATAACAGACGTACATGTTACCGATCGCAAATACAGCATCTGCGATATTTGTGGCCAGTCATTCAGGACTAGACGTTTGAAAAGCCATATGAAAAGACATGAAGACGATCATAAACGAGTTAGTCACACCGGAAAACACATTTGTAATACTTGCGGTAAACAGCTGGCCACAGCTAAAAGCTTAAGAACTCATCGTTTACGCCATTTAAAACAGTACAAATTCGTTTGTGATACTTGTGGTCAGGGTTGTATGACGACGGATGAGTTCCGTCAACATACAAATCGAAAACACCTCAAAGTAGAACGAAAGAAAGCTGAAAGTCAGAAAACATCACAAGATGAATGTATGTACTGTTCAAAAACTTTTCGTTCTGCCTATCGCTTAGAGGTGCACTTATCCACTCATATTGATGGTAAACCATATTCCTGTAGTGTATGCGAGAAATCTTTCAAACGATTAGAACTCTTAGAAGAGCATAGATGTATAAGCGACCGTATTAAAAAATACAAATGTGACATTTGTGGCATGAAGGTTAGTTGCGAGAAAACTCTAAAGAGACATCGCTTGCGACATTTAAAACAATTTAAATTTGTTTGTGACACTTGCGGGCATGGTTGTATGTCGAACAGCGAACTCCGCCAGCATGTTGATAAAATACATCTAAAAATATCCAAAACCGATCTTTGTACAGTTTGTGGCCTATCAATTACAACGGAAAATATAAAACAACATATGAAAACTCATGAAGAAGGCTACAATCAAAACCGTAAAATTGCATGCAAATTCTGCTCGAAACGTTTCTTACAGAAAATCCACTTGAAGAATCATATTCGAAGAATGCACAATGAGGCACGCCCAAAACATACTTGTGATATCTGTAAGAAAGAATATGCCAGTACTTATGAATTCGAATGCGATATCTGCCATAAGAAGAGCACCTGTTACGGTAATTTAATGTTGCATCGTCGACGACATTTGAAAGATTACAAATTCAGCTGTGAAATCTGCGGGCAAGGCTTCATCTCGAACAGCGAATACAAGCAACACATAGAAGGCAAACATAATCGTACACATCTGTGCAACATTTGCGGTAGATCCTTCTACAATAAACAAGGATTAGATTCGCATATGAAACGACACGAGGAGAATTACACAGAGAAACGCAACTATAAATGCGAATATTGCCCGAAAACGTTCATGCAAGAGATGCATTTGAAGAAGCACCGCCGACGTATGCATAACGATAGCCGGCCGAAATTCATTTGTGATTTATGCGGTAAAGAATTGGCAAGTCGTGGCGGTTTACAATACCATAAAAACGTCCACGATGGCATTAAAGAGAACGAATGTAACCTATGCGGGAAGAAGTTCAATCGTAAAGACACGTTAGTGCAACATATGCGTACGCATTCTGGTGAACAGCCGTACAGTTGTCCTTTCTGTGGGAAATCGTTCACGCAACGATCGCCGTTGACGATTCATATGCGGCAACATACTGGAGAGAAACCGTATGAACTACCGATTGGTGTTTCGTTACAATGTCCGCAGTGTTTGAAAACTTTAAAAAGTCGAGACATATTGAAGAAACATTTACAGTATGTCCATACAGAAGACCGTCCGTATTCCTGTAATATTTGTAATAAATCTTATAAGCATATCAGTTATTTAAAATCGCATCAAAATAAACATAATGGTAGTGCTAAATATGAATGTGATATATGCCAAAAACAATTAACAAGTAATTATAATTTAAAGACACACAAGAAACACCATTTACAACAATACCAGTACAGTTGTGAAATTTGCGAGAAAGGCTTTATTACAAATAGTGAATACAAGAAACATATGGAAAGTACTCACAATCGAACGAATTTGTGCAATATTTGTGGACAATCGTTTTACAACAAGCACGGTTTAAATTTGCACATTAAACGACATGCCCAAGACTACAAAGAGAAGCGTGATTTTAGATGCGAATTTTGCCCGAAAACCTTCATGCAATTCTTCCATTTAAAGAAGCACATAAGGCGGATGCACAACGATAATCGACAGAAATACGTCTGCGATTTGGAATTTACATGGACGCCGAGCGAATCAGTTCAATGTTCTGAATGTTCGAAATATTTCAAAACGAAACGCTCGTTGAGAATACACACGCGTTCTGTACATTCACAAGATCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACATCGTATAGTTTGAAGGAACATAAACGCCGTCATTTGAAAGATTACCAATACAATTGTCAATTATGTGGGAAACTTTTCGTATCGAACGGTGATTATAAACAACACATGGATGGCCAGCATAACAAACGACATCTTTGCAATATTTGCGGCAAATCCTCGTATGACAGACATGCATTGATAAGGCATATGAGACGGCACGAAGAAAACTATACAGAGAATCGTAATTTCAAATGCGAATATTGCCCGAAGAAATTCTCGCAGATGTTCCATTTGAAGAAGCACATAAAACGGATGCACGACGATAACCGCCAGAAATACGTTTGCGATACGTGCGGCAAAGAATTGGCGTCTGTTCAAAGCTTAAAACAGCATAAAGATCTGCATTTGGGCATTAAACCTGTCCATTGTGATATTTGCACGAAAACATTCGCTAAAAGGAAGACTTTGGTGCATGGCTCGAAAAAACCGAAACAATGCCCGAAATGCCCAAAGAAATTCCAACACGCTTCACAATTGAACAAACATTCGGCAATACACAACGAGAAGCGGCCGTATTCTTGTGATATTTGCAAGAAGACATTCAAACAAAAATACAGTCTAACCTCCCATCAGGTGGTGCACAACGATTCGAAACCTTACGAATGTGAGATTTGTTTGAAACGCTTGAAAAAATACCAAAGTTTCATCGATCATCGCCGGCGTCATTTGAAGGATTTTACAGAATTTTGCAAAGACTGCAATATCGGCTTCATTTCTAACGCCGAATATAAAGCCCACATGGACGGGAAGCACGGAAATCGTTCGAATATCTGTACGGTATGCAGCAAAACATTCTACTGTAAATACACGCTGAAATATCACATGAGACTACACGAAGAGGGCTACCGAGACAAGCCCAATTTCAGATGCGATTCATGTGGTAAATGTTTCTCGCAGAAATTGTATTTGAATCGTCACGTAAAAATGATGCATGAAAACGGCGGGCGGAAGTTCGTTTGCGATTTGTGTGGTAAAGAATTGCGGACAATGGTCAGTTTGCGGCACCACAAGAACGTCCACCAAGGTGCTAAACCGAATGAATGCAAACTGTGCGTGGCTGAAAACGCCCTTCAATGTCCGTTGTGTTCAAAGAAAATGCTCAACAGCAGCTGGAATAGGCACGCGCGTACGCATTGTCCAACCTATGGAAATCGTTGCGACATTTGCGAGAAGGTCCTCAAAGATCAACACAGTTTAAGTGTACATAAACGCAACGTTCACAATTCTATGGAGCATGAATGCGATATTTGCCATAAAAAACTCAAATATAGTCGAAGTTTGATAAACCATCGCTCACGCCACATCAAAGAACAGCAGAAAATGTGTAAAATTTGCAATATCGGCTTCGAATATCAACTCGACTTCAGGAATCATATGCAAGAAAAACACGAAATCCACCCCTATTCTTGTCCGATTTGCGGCAACACTTACCGATCGAATAATTGGTTAAAAGAACACATGAAGAAACATACAGATGATAATAATCAATCAACTTGTCCAGTATGCAAGAAGAAAGTTACATTTTTACGAAACCATATGGATCGGTTACACAACGATAAGCGAAATAATTACATTTGCGATTTGTGTGGCCATATGGCACTGCACAATGATGAATCTTTATGTAAAATTTGTAATAAGAAATTTGCACGCTTACAGCAGCATATGGATAAGGTGCATAATGAGAATCGTCAAACGAATATAAATGTAGAAAATTTAGATTTCCATGAAAATTCATTGATTACATATAATAATGATAATGGAGAATTTGAGGTTGATTATGGTAATTTCGATACTGATTCTGAGACGAATTTACAACTTGGTAAGATGAATTATTCGTAA
Protein Sequence: MDGLKRHLKRHTENFTIICELCGRRFLTNGEYKQHKNDIHDRANLCNVCGRSFCSKESLKNHMKRHDENYTKVHNFQCDFCSKRFRQDMHLKKHIRRMHNENRRKYICDLCNKELASQTGNECPEAQDLLIQFQLYSCNICQKTFKGKRTLYYHKSVHSNVKYECNICGKKLKSFSMLKIHRLRHLKQYKYTCEICGYGCMFNSELKSHITDVHVTDRKYSICDICGQSFRTRRLKSHMKRHEDDHKRVSHTGKHICNTCGKQLATAKSLRTHRLRHLKQYKFVCDTCGQGCMTTDEFRQHTNRKHLKVERKKAESQKTSQDECMYCSKTFRSAYRLEVHLSTHIDGKPYSCSVCEKSFKRLELLEEHRCISDRIKKYKCDICGMKVSCEKTLKRHRLRHLKQFKFVCDTCGHGCMSNSELRQHVDKIHLKISKTDLCTVCGLSITTENIKQHMKTHEEGYNQNRKIACKFCSKRFLQKIHLKNHIRRMHNEARPKHTCDICKKEYASTYEFECDICHKKSTCYGNLMLHRRRHLKDYKFSCEICGQGFISNSEYKQHIEGKHNRTHLCNICGRSFYNKQGLDSHMKRHEENYTEKRNYKCEYCPKTFMQEMHLKKHRRRMHNDSRPKFICDLCGKELASRGGLQYHKNVHDGIKENECNLCGKKFNRKDTLVQHMRTHSGEQPYSCPFCGKSFTQRSPLTIHMRQHTGEKPYELPIGVSLQCPQCLKTLKSRDILKKHLQYVHTEDRPYSCNICNKSYKHISYLKSHQNKHNGSAKYECDICQKQLTSNYNLKTHKKHHLQQYQYSCEICEKGFITNSEYKKHMESTHNRTNLCNICGQSFYNKHGLNLHIKRHAQDYKEKRDFRCEFCPKTFMQFFHLKKHIRRMHNDNRQKYVCDLEFTWTPSESVQCSECSKYFKTKRSLRIHTRSVHSQDRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTSYSLKEHKRRHLKDYQYNCQLCGKLFVSNGDYKQHMDGQHNKRHLCNICGKSSYDRHALIRHMRRHEENYTENRNFKCEYCPKKFSQMFHLKKHIKRMHDDNRQKYVCDTCGKELASVQSLKQHKDLHLGIKPVHCDICTKTFAKRKTLVHGSKKPKQCPKCPKKFQHASQLNKHSAIHNEKRPYSCDICKKTFKQKYSLTSHQVVHNDSKPYECEICLKRLKKYQSFIDHRRRHLKDFTEFCKDCNIGFISNAEYKAHMDGKHGNRSNICTVCSKTFYCKYTLKYHMRLHEEGYRDKPNFRCDSCGKCFSQKLYLNRHVKMMHENGGRKFVCDLCGKELRTMVSLRHHKNVHQGAKPNECKLCVAENALQCPLCSKKMLNSSWNRHARTHCPTYGNRCDICEKVLKDQHSLSVHKRNVHNSMEHECDICHKKLKYSRSLINHRSRHIKEQQKMCKICNIGFEYQLDFRNHMQEKHEIHPYSCPICGNTYRSNNWLKEHMKKHTDDNNQSTCPVCKKKVTFLRNHMDRLHNDKRNNYICDLCGHMALHNDESLCKICNKKFARLQQHMDKVHNENRQTNINVENLDFHENSLITYNNDNGEFEVDYGNFDTDSETNLQLGKMNYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -