Basic Information

Insect: Hybos culiciformis
Gene Symbol: zfh2
Assembly: GCA_964007475.1
Location: CAXFZM010000487.1:1-14517[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00016 0.012 16.6 1.4 2 23 73 95 72 95 0.96

2 12 4.1e-05 0.0029 18.5 0.7 1 23 127 151 127 151 0.92

3 12 0.013 0.93 10.6 0.4 1 22 277 298 277 301 0.91

4 12 3 2.2e+02 3.2 6.0 1 23 835 858 835 858 0.94

5 12 0.063 4.6 8.5 0.1 2 23 958 980 957 980 0.93

6 12 0.91 66 4.8 2.4 2 19 1047 1064 1046 1066 0.95

7 12 0.00087 0.063 14.3 1.5 1 23 1118 1140 1118 1140 0.96

8 12 0.0002 0.015 16.3 2.0 2 23 1147 1169 1146 1169 0.94

9 12 0.021 1.5 10.0 3.7 1 23 1291 1315 1291 1315 0.92

10 12 0.014 1 10.5 0.6 1 22 1337 1358 1337 1361 0.89

11 12 0.0063 0.46 11.6 0.1 1 23 1432 1456 1432 1456 0.93

12 12 0.96 70 4.8 3.3 1 18 1588 1605 1588 1609 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00016	0.012	16.6	1.4	2	23	73	95	72	95	0.96
2	12	4.1e-05	0.0029	18.5	0.7	1	23	127	151	127	151	0.92
3	12	0.013	0.93	10.6	0.4	1	22	277	298	277	301	0.91
4	12	3	2.2e+02	3.2	6.0	1	23	835	858	835	858	0.94
5	12	0.063	4.6	8.5	0.1	2	23	958	980	957	980	0.93
6	12	0.91	66	4.8	2.4	2	19	1047	1064	1046	1066	0.95
7	12	0.00087	0.063	14.3	1.5	1	23	1118	1140	1118	1140	0.96
8	12	0.0002	0.015	16.3	2.0	2	23	1147	1169	1146	1169	0.94
9	12	0.021	1.5	10.0	3.7	1	23	1291	1315	1291	1315	0.92
10	12	0.014	1	10.5	0.6	1	22	1337	1358	1337	1361	0.89
11	12	0.0063	0.46	11.6	0.1	1	23	1432	1456	1432	1456	0.93
12	12	0.96	70	4.8	3.3	1	18	1588	1605	1588	1609	0.82

Sequence Information

Coding Sequence: ATGCAACAGCAGCTAGCAATGTCACCGAATGCCGCTGGTAATAGTagtcagcagcagcagcagcaaccgTCGGCTAGTTTCACAATTGGTGCATGCCCCGAACATATTAACGGTCGACCATTGGGTGTCGATTGTGCAAGATGTGAAATGATATTGAATTCAGCCCGACTCAATAGTGGTGTTCAAATATCAACGCGTAATTCATGCAAAACATTGAAATGCCCGCAATGCAACTGGCATTATAAATATCAAGAAACATTAGAAATACATATGCGAGAAAAACATCCCGATGGCGAAAGTGCATGTGGATATTGTTTAGCTGGCCAACAGCATCCGCGGTTAGCACGTGGTGAATCCTATACATGCGGCTACAAGCCATATCGATGCGAAATTTGTAATTATTCGACAACAACTAAAGGGAATTTATCAATTCATATGCAAAGTGATAAACATTTGAATAATATGcaagaattaaataattcacaaaatatgcaaaatgcTGCAGCGGTTGCAGCGGCAGCAGCAGCCGCCGCAGCAGCTGGTGTAGCTGTTGCTGCAGCAGCAAATAATTCACAAAACACAAATCATCCAGCTCAATCATCTTGTAATCAAGGTGGCGGCCAATCTGTGGCacagcagcaacagcagcagcaacagcaacagcagcaacaacagcagcagcagcaacaagaTAGGCCGCAAAGTGTTCAAATCGAACAACAAATACGCGAAAGCCCTAAAATACTAATGCCAGGTATGCAATCACAGCAAACGGCAGCGGCTGCTGCTTCTGCATCCAATGTTGTTCAACAAAAACCGAAGCCATCGTTTCGTTGTGATGTCTGTTCATACGAGACATCGGTAGCTCGCAATTTGAGAATTCATATGACCAGTGAAAAGCATACACACAATATGGCTGTATTGCAAAACAATATGAAACATTTTCAAGCATTATCATTTTTGCAATCGCAGGCAGCTGCCCAGGCCACAAATAGTTTACCAAATTTAGCTGCAGCAGCAGCCGCAGCTGCCAATTTACCACAATTAACATCGGCTGGTGCTGCTGCGGCCGCTGCTGCTGCTGCCGCACATCAGTCACAATTATCgaatttgcaaaattttctaCCCGAAGCAGCATTGGCCGATTTAGCGTACAATCAAGCATTGATGATACAATTGTTACATCAAAATTCGGCTGCTGGTGCATTGAGTGCTGCAGCTGTTGCAGCCGCTGCAGCTGTAACTAATCCTAGTAATACTAATACAACCACAactaatagtaataataataataataataataataacaataataataataataataataataataataataatagcaatatTAGCATCACACAAGCTCAATTGCAATTAAGTAATGCTAAAACAAGTTTAGCAACAGCGACATCATCATCAGCAACAATAACATCCGTATCATcgacatcatcatcatcatcatcatcagtaTTAATAAcgcagcagcaacagcagcaacaacagctaTCAAGCCAACAATCTTTAGTCACATCAACTAACAatgacaacaacaacaacaacaacaacagtaaTAATAGTTCAGCGGCATTGGCAGCTGCTGCTGCCGCCGCCGCCGCTGCTGCTGCTGCAGCTAATACAGCATTATTAAATAGTTCAATTGAAACCGATCAAGGCTTGAATCCAGACACGCTGGAGCCACCAATTGAGCCCGACTTGAAGCCAACCACAATATTCAGCTGTTTGATATGTTcaatttataatacaaataatttggACGAATTAAATAATCACATTATtaattataattatggTATGCAACAGCAACAGCATTCAAATCAATCCGATTCATCATCTGCAACTGCTGAACATCATACTTCAACACAAcatcaacagcaacaacaacaacaacaacaacaacattcTTTGCATCATTCGCATCATTCGCTGCTGCTGcatcaacatcatcatcatcatcatagtGGTGGTGAGCAACAGCAGCAGAATAATGATTATGATTCGCTGGCATTATTCAATTTAACATCCGCATCTGCCGCGACAAAAACCTTATTAATATGCCAATTGTGTCAATATAAGGCTGGCACTATTTTGCATATGATGCAACATGTCAAAAGTATTCGTCATATGCAAGTCGAACAATTTATATGCTTGCAACGGCGTAGCGAACAATTGGATCAATTGGATTTGAGTGATGTATTTAAGATTTGTGAAAATGaCGCTATTAAAAGTGAACGCAGTAGTCCAATGCCGACGTCACCAACGTCGTCCAACAcaacaacaaatttattatttgatcgcAGCAATCTTTTACTGCATGACTCACAGCAATTGCAATTAACGCCGACGACACCGTTGCGACGAGACGCTGATGCAGCCAATAATTCTGGTAGCTCATCATCAACGTCTAGCGTTCTAATGCAGCCGTCCGCAGCATCAGCTCAAAATAATACGATTTTATCTCCCAATGGGCCAACAACTATTTACAAATGTCAACATTGTGATTATTTCTGTGAATTTAAACATGAAATTGAAATGCATTTAGAGCAGGTGCATACCAGCAGCAGCTCCGAAATGGATTATATAATGATTCCAACTACTCCGCAAGCAATTCAAGCGTTCCAAGCTGCAGTTCATGCGGCGGCAGCAGCAGCAGCGGCGGCCGCTTCTTCATCCAAAGATTTGCGCATCCAGTCACCATTGGAGGATTGCATTAAAAGAGAACAATGTGATGACGACGACGAATTGTTGGATGAAGATGATGCGATACCAATAAGTAGTGCTGGTGACGACAGCGGTGACGAAGGCGGCGGCAATCCAATGCGGCGCCGGCAATCAAAATCATCATCGGTAATGTGTCCGCTGTGTCAGGACAGTTTCAATGATAAGGTTAAATTGGAACAACATGTTATGGGTGTACACAGTGTGAACAGTGATGGACTGGCTAGATTGCTGCAACTGGTTGACACAACACATTGGTTAAATGATAGTAATTCAAGTAAAATTGTTGataatcaacaacaacaaagtGAATCAGTGTCGACGGCAGCAACCCATCACCAGCAGCAAGCCCTGCAGCAAATCGAATCGTCGAGTCTGACGATGCAACAGCTGGAATTGGAATGCTCACAATGTGGTAAGTTCTTGAAATCCCATCAGGAATTGCTGCAACACTGTCAGGACAGTCAGCATTATCAATTGAATTCGGCGGAACAATACAATTGTATATTTTGGAAACAGTGTCAGCAGAATTTCTTGAATCTGCCCGCAATGTTAACGCATTACAAAGATTCGCATATGAATCTTGTAATATCCGAACGTCATGTCTACAAATATCGCTGCAAACAGTGTTCGCTGGCATTTAAGACACAAGAGAAATTGAATGCTCATTCGCTGTATCATACGATGCGTGATGCCACCAAATGTATGATCTGCAATCGAAGCTTTCGCAGTACACAATCTCTGCAAAAACATATGGAACAATCTCATCCGGAGCACCAGCAACAACAACCGCAACAGctgcagcaacagcaacagcaacaacaacagcagcaacagcaacaataTACTGTCGGACCAATTTCTCCGGATTTGAATGAATCAGCTTCTTCAAAACTACAGCAACCTAGCTCTTTCCCACCACCAGCAGCAGATGATCATCAACTGGATTCACCACCACCAACTGCAGCTTCATCATCGCCAAAACAAGACGATGATGCGCTCAATCAGGAGCAACAATTTGATTCAATGATGATGCTGGAAGATCATCATCAGCAGCCGCAAACTGAATTAGACGAAATCCTAAATACTCAGCAAATGGCTGAGGAAAATTATAATGACGGACAGCGGAAATATAAGTGTCACAAATGCAAAGTTTCATATACAATTCAATACTATTTAATTGTACATTATAAATCCCAGCAGCATCGGAAGACCACCAGCAGCAACCAGCAATATCCGATCGAGAAATATTTGGATCCTAACAGGCCATTCAAATGTGACATATGCCGGGAGAGCTTCACCCAGAAAAATATCCTGCTGGTTCACTATAATAGCGTTTCACATTTGCACAAAGTCAAGaaacagcaacaacaaaaagAGAATAGTGTAACACCGCCGCAACTATCGCCATCGACGACGAGCGCCACTGATTTGGACAATAAAGCGGATGGATTCATTGAGACTACTACTGCTGATTGCTGCGATGAACAGCCGTCGTCATCAATTAAGCGAAAACTGAGTCCCGAAAATGATTATGATTCGCCGAAGAAACGTTTCAAATGCGACATCTGTAAAGTTGCTTATGCTCAGGGCAGTACACTGGATATTCATATGCGGAGTGTTTTGCATCAGACCCGTGCATGTCGTTTGCAAGAACAACAAATTCAGCAACAGCAacatcagcagcagcagcagctgcaATCCAGTTCTTCGCCaccgaatttgaataaaatttgcgAATTGAGCCAGCAGCAGATTCCAACTACCGCCACTGCCGCCGATGATataccaaaatttaataatcaaatcTATAAAACCCTGCTAGAGAATTTTGGTTTTGATATTGTGAAGCAATTCAATGAAATCAATACCACAAAAACTGGTTTCGGCGCCGGCGGAAATTTGACTGTGGAACAGCAACAGAAATTGTTGGCTTCACCGCCGACGTCCGCATTGCAACCGAAACCGGTTTCGTCGACAATCACCAGCACCGGCGGCAGCACCAGTGGTGGTGACGAAAAATATTATTGCCGTCACTGTAAGAAAGTTTTCTCATCAATATTCGTAATGAAAACTCATTGCGAGGAAATTCATAATGAGAAAATTCCGCTTGAATTTCTCGAAAAATTTGCCGAAAAATTTAAGACATATTATATTGGCGGCGAGAATGAGCAGGATGGCGGTGGCAGTGGCGAAGTTCTcgatttttcatcaaaaaaggGTTCGCCATCGCCAACGCTGTCATCGAGCAGTATTAAATTAGAAAAGTCGGATAGCCTGATGTCACCGGGCGGCAGTACCAAATCAGCAGTGCTGCAGCAGGCCACATCTCCAAATCCAAATCAGGCTACAATGTCGTTGCATAGTCCAGCATCGGCAACGaatcaacaacagcaacagcaacggCAAACACAACAACAGCAAACAACGCCATCTGACttgacgacgacgacgacgaaaCAAATGAACGTTGATCCGAATATTTTGGCGCAAAAAATACTTGAACAAAATTTATCTAACTTGCCGccaaatttttccaatttaccACAAAATTTACAAAGTCTACAGAATTTGCAGAATTTACAGAGTCTGCAAAATTTACCGAATCTCAATAATTTGCCATTAAATACCCTCGACATGCTTAACATCATGCAATTCCATCATTTAATGTCActgaattttatgaatttggcACCGCCATTGATATTCGGTGGAACACCGGGTCAATCGCAAACAAATTTGCCACCAATAACACCGGAGCCGGGGCCCTCtgttggtggtggtggtggtggaccCAGCACATCGTCCAGCTCGAATTCAAGCTGTGCCGGCGGTTCACAAAATTTGAATTGCACTAATCCGGCCAGCAGTAGCGTGCAATCGCCAACAACTCAAGCAGTGGCACAGGTACAATTATTGCAACAGCAAGCTGCCGCGGCAGCAGCTCAAGCTGCTGCTGCTGCCCAACAACAGGCTTCAAATAATCAAAAACGTGCAAGAACTCGCATCACCGATGATCAATTGAAGATATTGCGTGCccattttgatataaataattcACCGAGCGAGGAAAGCATTAtggaaatgtcaaaaaaagCGAATTTGCCAATGAAGGTTGTAAAACATTGGTTCCGCAACACTCTATTCAAGGAGCGTCAACGCAACAAAGATTCCCCCTACAATTTCAATAATCCGCCATCAACAACCCTAAATTTAGAAGAATACGAGAGAACAGGACAAGCAAAGGTTACCCCTTTAGTGGATTCTGGGGGTGGTGAACAACAACTTAATCATCCCCAGTTAG
Protein Sequence: MQQQLAMSPNAAGNSSQQQQQQPSASFTIGACPEHINGRPLGVDCARCEMILNSARLNSGVQISTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGQQHPRLARGESYTCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQELNNSQNMQNAAAVAAAAAAAAAAGVAVAAAANNSQNTNHPAQSSCNQGGGQSVAQQQQQQQQQQQQQQQQQQQDRPQSVQIEQQIRESPKILMPGMQSQQTAAAAASASNVVQQKPKPSFRCDVCSYETSVARNLRIHMTSEKHTHNMAVLQNNMKHFQALSFLQSQAAAQATNSLPNLAAAAAAAANLPQLTSAGAAAAAAAAAAHQSQLSNLQNFLPEAALADLAYNQALMIQLLHQNSAAGALSAAAVAAAAAVTNPSNTNTTTTNSNNNNNNNNNNNNNNNNNNNNNSNISITQAQLQLSNAKTSLATATSSSATITSVSSTSSSSSSSVLITQQQQQQQQLSSQQSLVTSTNNDNNNNNNNSNNSSAALAAAAAAAAAAAAAANTALLNSSIETDQGLNPDTLEPPIEPDLKPTTIFSCLICSIYNTNNLDELNNHIINYNYGMQQQQHSNQSDSSSATAEHHTSTQHQQQQQQQQQQHSLHHSHHSLLLHQHHHHHHSGGEQQQQNNDYDSLALFNLTSASAATKTLLICQLCQYKAGTILHMMQHVKSIRHMQVEQFICLQRRSEQLDQLDLSDVFKICENDAIKSERSSPMPTSPTSSNTTTNLLFDRSNLLLHDSQQLQLTPTTPLRRDADAANNSGSSSSTSSVLMQPSAASAQNNTILSPNGPTTIYKCQHCDYFCEFKHEIEMHLEQVHTSSSSEMDYIMIPTTPQAIQAFQAAVHAAAAAAAAAASSSKDLRIQSPLEDCIKREQCDDDDELLDEDDAIPISSAGDDSGDEGGGNPMRRRQSKSSSVMCPLCQDSFNDKVKLEQHVMGVHSVNSDGLARLLQLVDTTHWLNDSNSSKIVDNQQQQSESVSTAATHHQQQALQQIESSSLTMQQLELECSQCGKFLKSHQELLQHCQDSQHYQLNSAEQYNCIFWKQCQQNFLNLPAMLTHYKDSHMNLVISERHVYKYRCKQCSLAFKTQEKLNAHSLYHTMRDATKCMICNRSFRSTQSLQKHMEQSHPEHQQQQPQQLQQQQQQQQQQQQQQYTVGPISPDLNESASSKLQQPSSFPPPAADDHQLDSPPPTAASSSPKQDDDALNQEQQFDSMMMLEDHHQQPQTELDEILNTQQMAEENYNDGQRKYKCHKCKVSYTIQYYLIVHYKSQQHRKTTSSNQQYPIEKYLDPNRPFKCDICRESFTQKNILLVHYNSVSHLHKVKKQQQQKENSVTPPQLSPSTTSATDLDNKADGFIETTTADCCDEQPSSSIKRKLSPENDYDSPKKRFKCDICKVAYAQGSTLDIHMRSVLHQTRACRLQEQQIQQQQHQQQQQLQSSSSPPNLNKICELSQQQIPTTATAADDIPKFNNQIYKTLLENFGFDIVKQFNEINTTKTGFGAGGNLTVEQQQKLLASPPTSALQPKPVSSTITSTGGSTSGGDEKYYCRHCKKVFSSIFVMKTHCEEIHNEKIPLEFLEKFAEKFKTYYIGGENEQDGGGSGEVLDFSSKKGSPSPTLSSSSIKLEKSDSLMSPGGSTKSAVLQQATSPNPNQATMSLHSPASATNQQQQQQRQTQQQQTTPSDLTTTTTKQMNVDPNILAQKILEQNLSNLPPNFSNLPQNLQSLQNLQNLQSLQNLPNLNNLPLNTLDMLNIMQFHHLMSLNFMNLAPPLIFGGTPGQSQTNLPPITPEPGPSVGGGGGGPSTSSSSNSSCAGGSQNLNCTNPASSSVQSPTTQAVAQVQLLQQQAAAAAAQAAAAAQQQASNNQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSKKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYERTGQAKVTPLVDSGGGEQQLNHPQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00812636;
90% Identity: iTF_00812636;
80% Identity: iTF_00812636;