Basic Information

Insect: Hybos culiciformis
Gene Symbol: GLIS3
Assembly: GCA_964007475.1
Location: OZ023274.1:44524027-44532634[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3e-05 0.0021 19.0 0.7 1 23 60 82 60 82 0.98

2 17 0.00021 0.015 16.3 1.1 3 23 90 110 88 110 0.98

3 17 0.00034 0.025 15.6 2.9 1 23 116 138 116 138 0.98

4 17 0.0082 0.59 11.3 0.5 1 23 145 167 145 167 0.95

5 17 1.1e-06 7.9e-05 23.5 0.6 1 23 174 197 174 197 0.97

6 17 0.0012 0.09 13.8 0.4 1 23 203 225 203 225 0.98

7 17 6.7e-05 0.0049 17.8 1.8 1 23 232 255 232 255 0.97

8 17 9.1 6.6e+02 1.7 0.5 1 9 264 272 264 278 0.82

9 17 0.16 12 7.2 0.6 1 23 349 377 349 377 0.98

10 17 0.02 1.5 10.0 3.9 1 23 569 592 569 592 0.93

11 17 6.9e-05 0.005 17.8 0.9 3 23 613 634 612 634 0.97

12 17 1.4e-06 0.0001 23.1 0.3 1 23 640 662 640 662 0.98

13 17 1.5e-06 0.00011 23.0 2.4 1 23 668 691 668 692 0.96

14 17 0.00032 0.023 15.7 0.6 1 23 719 742 719 742 0.96

15 17 0.11 8.1 7.7 0.0 3 23 984 1005 983 1005 0.92

16 17 1.5e-05 0.0011 19.8 0.8 1 23 1011 1033 1011 1033 0.98

17 17 0.00037 0.027 15.5 2.6 1 23 1039 1064 1039 1064 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3e-05	0.0021	19.0	0.7	1	23	60	82	60	82	0.98
2	17	0.00021	0.015	16.3	1.1	3	23	90	110	88	110	0.98
3	17	0.00034	0.025	15.6	2.9	1	23	116	138	116	138	0.98
4	17	0.0082	0.59	11.3	0.5	1	23	145	167	145	167	0.95
5	17	1.1e-06	7.9e-05	23.5	0.6	1	23	174	197	174	197	0.97
6	17	0.0012	0.09	13.8	0.4	1	23	203	225	203	225	0.98
7	17	6.7e-05	0.0049	17.8	1.8	1	23	232	255	232	255	0.97
8	17	9.1	6.6e+02	1.7	0.5	1	9	264	272	264	278	0.82
9	17	0.16	12	7.2	0.6	1	23	349	377	349	377	0.98
10	17	0.02	1.5	10.0	3.9	1	23	569	592	569	592	0.93
11	17	6.9e-05	0.005	17.8	0.9	3	23	613	634	612	634	0.97
12	17	1.4e-06	0.0001	23.1	0.3	1	23	640	662	640	662	0.98
13	17	1.5e-06	0.00011	23.0	2.4	1	23	668	691	668	692	0.96
14	17	0.00032	0.023	15.7	0.6	1	23	719	742	719	742	0.96
15	17	0.11	8.1	7.7	0.0	3	23	984	1005	983	1005	0.92
16	17	1.5e-05	0.0011	19.8	0.8	1	23	1011	1033	1011	1033	0.98
17	17	0.00037	0.027	15.5	2.6	1	23	1039	1064	1039	1064	0.98

Sequence Information

Coding Sequence: ATGAATCATAATAAGAATTCATCAAATAGGAGTTATTCATTTAAAGGTcgcaagaaattaaaaaaagagaatttATCCACGCAAAAAAAGTTACCTGACGGTTATTGGCGATGTCTTATTTGCGGTCAAACCTTGAAACTAGAATTTAAAGAAGATCATTTGAAAAcacataagaaatttatttgcgAATCATGTGGAAAAGgatTTGATCGACGTTTCCGTTTGACAATACATATTCGAACTCATACAGGAGAACGTCCATTTGGATGCCCTTATTGTTCAAAAACTTTTACAACTGATCGAGTATTAAAACAACACGAAAGGAcacatttgaatttaaaaccATTTCAGtgtacTTCGTGTTTGAAAAGTTTTACAACAAAAAACTCGTTATTTGTTCATGAAAAAAGCCATTCATTGGCTATATCGACTTATAAATGTGATCTTTGTCCTAAAAAATTTCCTACTGAACAAAGAATGATCGATCATCGTGGACGGCACAAATTTGAAGGGAAAACATTTCAATGTTCACAATGTCCAAAATCTTTTGCACTTAagtacaatttAACAGCTCATATAAGATTATCTCATAAAGGTGAATTTAATTACAAATGCGATTTTTGCGACAAGgtGTTCATACAAGTTGCAATGAAAAGATCGCATCAAATTGTGCATACCAGAATTGGACAACCATTTCAATGTactttatgtgaaaaaaaatacgCAACAAATGATGGCTTAAGAAAGCATAAAAAAAGAGATCATAAGCCAGATTTACCACCAATTAAATATCGTTGCAATAAATGTGATATGCATATTCAACAAAAagacaaaaaactaaaattagaaaatgttgaaattgaaattgaagacCCACTAAAATTACCAGCAGCAATATCATCAACAACTGAACTAAAGGATGTTAAGTTTAATAATGATATTGATGAACAaacagatgaaaaaaatttagaaacaaacAGCCAGCTGCAACAACAAACAGCTGCTTTAAATAGTAGTTCTACAGCTGAAcctaaaaacaattattatcaaTGTAATTTGGTCAAGTgtggttttaaaattttgaaaatatttgaaaatcgtGCAAAATTTCTCGAACACTTAAAATCTCATAAATTCCAATCAGCAAAATTGGAATTTATTCCATCAGTATTAAATTCCAAAGAATTATCTGTTGCTGTTTCTTCTAATtcagctgctgctgctgctgcttcaTCAATTTTAGATGTTTATGCAAATAACACTACTATTGCATTGGAATCAAGAGAAGTAAATGAtgataaacaaatattattatcaaattatgaTGAACAACTTCCACAAACAGTAGTGATTAAAGAAAAACCTTTAGATATAGTTAAGACAGTGAAAAAACTTCCAACTGTACAtgacaaaattaaattggaacAAATTCAGGCCCTGAATAGGCCCAGAAAACTACCAACCATCCAAGGGAAtgcaaatttcaataaaagaaaacttaaaacgGGAAATGACACGGATACGAACAATGATGGGctaagtaaaattaataatcgATCATTTGAAATGTATCCAGATAAATCTGTTATATTGTTAGTTGATGATGTTATAACGAAAGTGCATGGTGctcaaaaattaacaaataatgataaaaatattgtgaCGGTGACAgcacaacaaaaattatttaataaaaaaccatactttttttgtgatttgtGTGAAGTACGTTTTACACACAGATCATCCTATAATAAGCATAATTTATCACAACATTCAGAAGTGATTGCAATTGATGATAAAACTGGTGAACGTTTAGATGGCAAACAAAGAATTTGCAATCATTGTAATCAAGTATTTTCAAGAGCTTcagtcTTAAATCAACATTACCTTACTGTGCATCTTAAGCAGAAACCATTCGAATgtgattattgtcaaaaaaaatttgcggcaAAAAGTAATCTAATTGAACACATTAGAATTCATACAGGTTCAAAGCCTTATAATTGTCCAGattgtgataaaaatttttcttatagatCAACATTAACGACACATATAAAAAATGTCCATCACACAAATAtactaaattttgataatttgccAATGTTAGATGATGAcatctCTCCAATGGTCACTGATATGCGACGAagttatatttgtaatttttgtacaCGTAATTTTTCATCTAAAATAGATGTGATTCGACATATGATGCAGGTTCACAAAGTTAATTCAGTTACATCGATATGTCAAATTGATGAAACACTTAATGCGGATATAACAAAGAATTATTCTGTTggttcaataataaaaattcctcaaacatcattaaatacaaaaaattcagaCCAGAAAGAAGAAACTATAACCCAACCGAATGAAGTTGGAgtaaaaaaagaagtaataatTCCGGcagttgaaattgaaaataattctgCGGAAACATTATTCGAAATTTCTTATGAGAAAGTTCAAAATAATGATGAAGAATATTTAtgtgaagaaaattttgttgcAACTGAAACTTGTGACACTGAAAATTTTGCAATAGCAACTTATGAAAATGTTTACACAGAAAATTCATCAAATGTTATCGAAGAAAATCATATAAACGAAAATTGTATTCAAAAAGAACCAGAAAATGAGTTTGACGAAGatgatatagaaaattttttaaatgcaagtATTGTCAAAGTAGATGGATCAGTAGATTACATTGATCAGAACGCTATTACAGTAAATGATGATTCTGAAATTTATGAAGTGGAATATCTAGAAGATTATGATGGTGACGATAATGATAGTATCCGATCTGTATCCAATTCAAAACACTCAGACAGTTACGAAGTAAATagtataaatttagaaaatgaagtTACTCAACTTGAGGAAACCCCACTTGCTGATTTGGCTAAACTATTTGTAGATCCAAAAAATCCTAGAAGATGTATTgaatgtaatgtaattttttcaaGGCCTGCGGTACTTTATCAACACATCAAAAtagtacattttaaaataaaatcatattcatgcaaatattgtaataaaacatTTGGAGCTAGCAGTAATTTGTCAGAGCATGAAAGAATACATACAGGGGAAAAACCATACAAATGTACTGCAGGGTTTTGCAACAAGGCATTCAGTAGGAGAACGGCTTTTGTACACCACGTAAAAACCAATCATCCATGTAACATAACTGAGATTATTCGAAACAGTAATAACAATGCCAAATAA
Protein Sequence: MNHNKNSSNRSYSFKGRKKLKKENLSTQKKLPDGYWRCLICGQTLKLEFKEDHLKTHKKFICESCGKGFDRRFRLTIHIRTHTGERPFGCPYCSKTFTTDRVLKQHERTHLNLKPFQCTSCLKSFTTKNSLFVHEKSHSLAISTYKCDLCPKKFPTEQRMIDHRGRHKFEGKTFQCSQCPKSFALKYNLTAHIRLSHKGEFNYKCDFCDKVFIQVAMKRSHQIVHTRIGQPFQCTLCEKKYATNDGLRKHKKRDHKPDLPPIKYRCNKCDMHIQQKDKKLKLENVEIEIEDPLKLPAAISSTTELKDVKFNNDIDEQTDEKNLETNSQLQQQTAALNSSSTAEPKNNYYQCNLVKCGFKILKIFENRAKFLEHLKSHKFQSAKLEFIPSVLNSKELSVAVSSNSAAAAAASSILDVYANNTTIALESREVNDDKQILLSNYDEQLPQTVVIKEKPLDIVKTVKKLPTVHDKIKLEQIQALNRPRKLPTIQGNANFNKRKLKTGNDTDTNNDGLSKINNRSFEMYPDKSVILLVDDVITKVHGAQKLTNNDKNIVTVTAQQKLFNKKPYFFCDLCEVRFTHRSSYNKHNLSQHSEVIAIDDKTGERLDGKQRICNHCNQVFSRASVLNQHYLTVHLKQKPFECDYCQKKFAAKSNLIEHIRIHTGSKPYNCPDCDKNFSYRSTLTTHIKNVHHTNILNFDNLPMLDDDISPMVTDMRRSYICNFCTRNFSSKIDVIRHMMQVHKVNSVTSICQIDETLNADITKNYSVGSIIKIPQTSLNTKNSDQKEETITQPNEVGVKKEVIIPAVEIENNSAETLFEISYEKVQNNDEEYLCEENFVATETCDTENFAIATYENVYTENSSNVIEENHINENCIQKEPENEFDEDDIENFLNASIVKVDGSVDYIDQNAITVNDDSEIYEVEYLEDYDGDDNDSIRSVSNSKHSDSYEVNSINLENEVTQLEETPLADLAKLFVDPKNPRRCIECNVIFSRPAVLYQHIKIVHFKIKSYSCKYCNKTFGASSNLSEHERIHTGEKPYKCTAGFCNKAFSRRTAFVHHVKTNHPCNITEIIRNSNNNAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -