Hcul012470.1
Basic Information
- Insect
- Hybos culiciformis
- Gene Symbol
- -
- Assembly
- GCA_964007475.1
- Location
- OZ023273.1:112642829-112649376[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 7.7e-05 0.0056 17.6 1.8 1 23 508 530 508 530 0.96 2 18 0.00011 0.0081 17.1 0.3 1 23 536 558 536 558 0.97 3 18 0.0001 0.0075 17.2 1.7 1 23 564 586 564 586 0.98 4 18 3e-05 0.0022 18.9 3.1 1 23 592 614 592 614 0.97 5 18 6.9e-05 0.005 17.8 4.7 1 23 620 642 620 642 0.99 6 18 0.00017 0.012 16.6 5.5 1 23 648 670 648 670 0.96 7 18 1e-06 7.2e-05 23.6 3.7 1 23 676 698 676 698 0.98 8 18 6.9e-06 0.0005 20.9 3.0 1 23 704 726 704 726 0.97 9 18 0.00013 0.0094 16.9 6.7 1 23 732 754 732 754 0.97 10 18 0.00068 0.049 14.7 6.6 1 23 760 782 760 782 0.97 11 18 6.3e-06 0.00045 21.1 4.5 1 23 788 810 788 810 0.98 12 18 1.5e-05 0.0011 19.9 8.1 1 23 816 838 816 838 0.98 13 18 8.8e-06 0.00064 20.6 7.9 1 23 844 866 844 866 0.98 14 18 4.6e-06 0.00033 21.5 7.7 1 23 872 894 872 894 0.98 15 18 0.00042 0.03 15.3 9.5 1 23 900 923 900 923 0.95 16 18 0.00075 0.054 14.5 0.6 1 23 929 951 929 951 0.96 17 18 0.0011 0.079 14.0 4.3 1 23 961 983 961 983 0.99 18 18 1.2e-05 0.00085 20.2 1.7 1 23 989 1012 989 1012 0.96
Sequence Information
- Coding Sequence
- atgaattcggAGTCGCATTCAATAATTGAGGCAACTTCAACTGTTGTCTCAAGTATTGGTGGACATTCGTCAGTAACTTCGACAGAATCAAGGCAGCAACAAGATCAATCTTCGCAATCATCAACCAGGCATCATCATCATTCACAGCAACTGGGGAatgaaCATGAGAGTCGTATACATCAAGTTCAGGGTGTTATTCAGCCGGTTAGTGAAGCCGAAATCAAACACACTGCACTCCCAATTTCGAACGCGCCCCCGttggGAAAGTACTGGGTTGTTACAAATTTATTCCAAGGCCCTGGTGGTCAAACAACAACAACCTATAATTTAGCTTCTTCACCAACTCCATCATCTTCAAATGTCGCAACCTTAACTCCAACAATTTCAACTGCACATACTGCTGTGTCTGTGAAAAGTGCAAtaactaaaaatgaaataataaagcAAGAACAACAAGAAATTCAACAACATAGACATACTCCTCTGATTACTCAGGTAGTTACCTCCTCCAGTCCCATACAAATTCCACATCCAATGATAATCACATCAGCACAACCTCACCAtcatcatcaacaacaacaacatcaacatcatcatcatcatcagcagcagcatcatcatcatcatcatcataatgGCACAACGACAATTATTACCACGGCTGCACAACAACAGTCTCAAGATGACCAACAAGAACTTCAGGCGGATCATCAGCATTCAGCATCGGATCATAATGTCGTTCATGTTAGTTCCGATGATAATATTATGGTTATGAATGCTACTCCTATTAGTAAAGCTGAAGGTAGTAAGATAATTATTGAGCCTATGTCAGTTGACCGGCACGCGACAACAATTCATACAATTCATGAATCAAATATAAAACAAGAGAAACAATCATTTAATGGTTACAATAGCGGAAAAGcgattgaatttcaaattcaaccGGGAAATCATATTACCACTTCTACTGACACCAAAGCCCAAGTTCCGCATATATTAGATGTTAGAAATGTTGATGGTTCTTTTATACGGATACAGCCAAATGATCAAGAATTGGGTAAAACAAGTGGTATTGAAATGTATAAAGTGAATATAGAAGATTTAagtcaatttttatcatatcaTGAAGTGTTTGGTAAAATTCATGGTGATGTGATACCAATTCACACAACCAGCAGTCCAACTGCAACTCATCAAATTCAAACTTATCAAATGCCTtcacaacaacagcaacaaactCAGGTTATTACAACTACAACTTCTAATTCTAACGATCAGGAACATATTCCACTGAGTGGAACATTATCAAATGCGACTGCTGTTATTGATGCAGTAGCTACTGGTCAAATATCATCAAATCAACAACAAACTGAACAAGAAATATCAACCAAAGCTGAACTAATTATgccaaaaatggaaaatattagtAGTGGGACAGCAACTATTCAAATTTCCGGAATAAATCAAGGCCAGCCCATAATTCAAACTTTACCAGATGGCACTGTGATTTCAACAGCTACACATGCATGTGATATTTGTGGTAAAATGTTTCAATTTCGTTATCAATTAATTGTTCATCGAAGATATCATAGTGAACGAAAGCCATTTAATTGTCAAGtttgTGGACAGGGGTTTAACACATCTCAAGATCTGACACAACATGGCAAAATCCATATCGGTGGTCCGATGTTTACTTGCACGGTTTGCTTTCATGTATTCGCTAATGATGCTAGCCTTGAACGTCATATGAAACGACATTCAACTGATAAGCCGTTTGCTTGCACAATTTGTCAAAAAACTTTTGCTCGAAAAGAGCATTTAGACAATCATTTTAGAAGTCACACAGGCGAAACTCCGTTTAGATGTCAAtattgcGCTAAAACGTTCACAAGAAAGGAGCATATGGTCAATCATGTTCGAAAACATACAGGGGAAACACCACATCGCTGTGACATTTGTAAAAAATCATTTACAAGAAAAGAACATTATGTCAATCATTATTTGTGGCATACTGgagaaACTCCTCATCAGTGTGAAGTTTGTGGCAAAAAGTACACAAGAAAAGAGCATTTGGCTAATCATATACGATCGCATACAAATGACACTCCTTTCAAATGTGTAAGTTGTGGGAAAAGTTTTAGTAGAAAAGAGCATTTTACAAATCATATATTATGGCATACTggtgAGACACCCCATCGGTGCGATTTTTGTTCGAAGACATTTACGAGAAAAGAACACTTACTAAATCATGTCCGCCAGCACACAGGAGAATCTCCTCATCGATGTACATATTGTATGAAAACGTTTACGAGAAAAGAACATTTAGTTAATCATGTTCGACAACACACTGGTGAAACACCATTTAAATGCACTTACTGCACAAAAGCCTTTACTCGAAAGGATCACATGGTAAATCATATTCGTCAACACACTGGAGAGTCTCCGCATAAATGTACATATTGTACTAAAACTTTTACCCGGAAAGAGCATCTTACCAATCATGTGCGTCAACATACCGGTGAATCACCTCACAAATGTTCGTATTGTAATAAATCATTTACGAGAAGAGAACATTTAACAAATCATACACGCTTACATACCGGTGACTCCCCACATAAATGTGAATATTGTCAAAAGACTTTTACTCGAAAAGAACATTTAACGAACCATTTACGTCAACACTCAAGTGATAATCCTCATTGCTGTAATgtTTGCAATAAACCATTTACTAGAAAGGAACACTTAATAAATCATATGTCTCGATGCCACACTGGTGATCGCCCTTTTACTTGTGAAACTTGTGGAAAATCTTTCCCATTGAAAGGAAATTTATTGTTCCACGAGCGAAGTCATATGAAAGGACTTCCACAGGATCGGCCATTCAAATGTGAAAAATGTCCAAAAGATTTTATTTGCAAAGGGCATTTAGTCTCCCATATGAGATCACATTCTGGGGAAAAACCTCATGCTTGTACATTATGCAGTAAAGCTTTTGttgaaaaaggaaatttaaaacGTCATATGAAAATGAATCATCCAAATGCTGTTATGCCACCGCCATTACCACCACCTACTATTATACCGGCTGTGCAAATTAAACAAGAACCCAACACTAATGCAATAAGTACAGTTACAACCATAACTAAGCCTCAACAATTTGTAAATGAAAGAATTCCAATGATAAAAACTTCGACTAATATAATACCTATATCCAATGTGTCATCAAACCAACCAACAATTCATACTATTCaacaaattacttcaaatttaaataCGTCATCATCTTCTGGGCGACACTCTGGTGCTAACCAAATTGTTTCCTCTGGTAATTTAATTCCCATTCATCATATATCAACATCAAACATTAGCACAACAACCGTTCCAAATAATAATCAGCAGCAAACCATAGTTTCTACTGTTCCAATTATAACATCAACTATAACCAAATCGAACAATAATCAGCAGGCAGTTTTGATTCAGCATACCGGCCATCAATCCCATCATGGGAATGAGGTTATTATACAAGGTAGACCACCACCATCTTCGTCAGCGGTACAAATGCATCAAGTAACTATAAGTAATCATTCACAACAACAGGAACAGagtaataataatgaacatCAATCAACACAACAGCCAGTACCAATTACAATACTTTCAACACAAAATATAGAAGATGCTTCCATAAATCGTACAGCTATACTTCAACATGTTGAAACTCACCCagtgtattaa
- Protein Sequence
- MNSESHSIIEATSTVVSSIGGHSSVTSTESRQQQDQSSQSSTRHHHHSQQLGNEHESRIHQVQGVIQPVSEAEIKHTALPISNAPPLGKYWVVTNLFQGPGGQTTTTYNLASSPTPSSSNVATLTPTISTAHTAVSVKSAITKNEIIKQEQQEIQQHRHTPLITQVVTSSSPIQIPHPMIITSAQPHHHHQQQQHQHHHHHQQQHHHHHHHNGTTTIITTAAQQQSQDDQQELQADHQHSASDHNVVHVSSDDNIMVMNATPISKAEGSKIIIEPMSVDRHATTIHTIHESNIKQEKQSFNGYNSGKAIEFQIQPGNHITTSTDTKAQVPHILDVRNVDGSFIRIQPNDQELGKTSGIEMYKVNIEDLSQFLSYHEVFGKIHGDVIPIHTTSSPTATHQIQTYQMPSQQQQQTQVITTTTSNSNDQEHIPLSGTLSNATAVIDAVATGQISSNQQQTEQEISTKAELIMPKMENISSGTATIQISGINQGQPIIQTLPDGTVISTATHACDICGKMFQFRYQLIVHRRYHSERKPFNCQVCGQGFNTSQDLTQHGKIHIGGPMFTCTVCFHVFANDASLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYLWHTGETPHQCEVCGKKYTRKEHLANHIRSHTNDTPFKCVSCGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCTYCMKTFTRKEHLVNHVRQHTGETPFKCTYCTKAFTRKDHMVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGESPHKCSYCNKSFTRREHLTNHTRLHTGDSPHKCEYCQKTFTRKEHLTNHLRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHERSHMKGLPQDRPFKCEKCPKDFICKGHLVSHMRSHSGEKPHACTLCSKAFVEKGNLKRHMKMNHPNAVMPPPLPPPTIIPAVQIKQEPNTNAISTVTTITKPQQFVNERIPMIKTSTNIIPISNVSSNQPTIHTIQQITSNLNTSSSSGRHSGANQIVSSGNLIPIHHISTSNISTTTVPNNNQQQTIVSTVPIITSTITKSNNNQQAVLIQHTGHQSHHGNEVIIQGRPPPSSSAVQMHQVTISNHSQQQEQSNNNEHQSTQQPVPITILSTQNIEDASINRTAILQHVETHPVY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -