Hcul013879.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hybos culiciformis
Gene Symbol
PZF1
Assembly
GCA_964007475.1
Location
OZ023273.1:139144760-139155133[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.00018 0.013 16.5 2.9 3 23 95 115 93 115 0.97
2 26 2.4e-05 0.0017 19.3 0.7 2 23 224 246 223 246 0.95
3 26 0.013 0.96 10.6 1.0 1 23 252 276 252 276 0.97
4 26 0.0033 0.24 12.5 0.4 1 23 287 309 287 309 0.99
5 26 0.00019 0.014 16.4 0.9 1 23 318 340 318 340 0.98
6 26 0.0029 0.21 12.7 2.9 2 23 347 369 346 369 0.94
7 26 3.3e-06 0.00024 22.0 2.2 1 23 375 397 375 397 0.98
8 26 1.6e-05 0.0011 19.8 0.6 1 23 403 425 403 425 0.96
9 26 0.0016 0.12 13.5 0.1 1 23 431 453 431 453 0.98
10 26 0.0061 0.44 11.7 1.1 1 23 459 481 459 481 0.98
11 26 0.024 1.8 9.8 2.7 3 23 489 509 487 509 0.95
12 26 5e-06 0.00036 21.4 0.9 1 23 515 537 515 537 0.99
13 26 0.011 0.8 10.9 2.1 1 23 543 565 543 565 0.96
14 26 1.3e-06 9.1e-05 23.3 5.5 1 23 674 696 674 696 0.98
15 26 8.2e-06 0.00059 20.7 0.7 2 23 832 853 831 853 0.97
16 26 0.035 2.5 9.3 2.2 1 23 859 883 859 883 0.97
17 26 2.4e-05 0.0017 19.3 0.5 1 23 898 920 898 920 0.99
18 26 0.00024 0.017 16.1 2.6 1 23 929 951 929 951 0.97
19 26 0.0032 0.23 12.6 0.7 2 23 958 980 957 980 0.93
20 26 2.7e-06 0.0002 22.2 4.3 1 23 986 1008 986 1008 0.98
21 26 1.1e-06 8e-05 23.4 1.2 1 23 1014 1036 1014 1036 0.94
22 26 2.8e-05 0.0021 19.0 0.3 1 23 1042 1064 1042 1064 0.98
23 26 0.0038 0.27 12.3 1.4 1 23 1070 1092 1070 1092 0.98
24 26 0.00014 0.01 16.8 1.4 1 23 1098 1120 1098 1120 0.97
25 26 3.8e-06 0.00028 21.8 1.5 1 23 1126 1148 1126 1148 0.99
26 26 0.0041 0.3 12.2 2.7 1 23 1154 1176 1154 1176 0.98

Sequence Information

Coding Sequence
ATGTTGGATAAATTGTGCCGTGCCTGCATGACATCCGAAGATGAGGAGGACAAGCTGTTTGAAGAATTCaatgaaaaagatgaaaattttaagcaatttattcaattaacatcaataacaattgaaaaattaaaaatttgtgaaaattgtcAAATCGAATTGTTGAATGCtattaagTTCCGATCAAAATGCATTGATTCTGATAAAAGAATTCGTGAAAATTACAACATTCCAACAACACCAAAATTCGAAGAAAACAGttcaataaaaaaaaaatttggttgccaattttgtgataaatattttacaagaaGTAATAGTTTAAAACGTCATTATAAACTTCACACAAAGGAAATCCTGAAAATTTCGATTGAAATTGATACAGATTTGAATGATAATTCCGacgaaattgaaaatgataaaacaGAAGAGTTAACTACAAAATTAGGGAATGACATTGAATTTCTTAAAAGCACAGAATCTGaaaacttcttaaaaaaaaaaaaaattgatttaattgacGATCCAAAAgatgaaaacttttttgttgGGAAAGGACAtagtaatgaaaatgaaattgaagttaatgaacataaaaaaatttctgtagaCTGTGAAAACATAACCATTGAAAAACcaaatccaaaaaataaacGTAGAAAATTAACTTCATGTCCGGTTTGTAATAAAACATTTGAACGTAAATATCGTTTAGCACGTCATTTAAATAATGTTCATGATCCGAAAAAACCTTATGAATGTGATTATGATCTCTGCAAAATACGTTTTCAAACAGAATATGGCTTAAAACGTCATAAATTATCCCATAcaccaaattttaaaaaattaaatgagttTTATCAGTGTCCTGATTGTTCaagtaaatttgaaaaaatagaaGCTTTATCAACACACAGaCTTACGCACAAAAAAAGCATATCTGAAGAAAAATTTGTATGCGACATTTGTTTAaagGTGTTTGATAAAAGAAATTTGCTCACACGACATTCCCAAACACATGAAGAAAATAAACATTGGCAATGCAAAGTATGTGATAAATGTTTTACTATTAAATCGAAGTTCGTGGAACATAGTAAAATAACACACCAAGTTTTAAAGCCTTTTACTTGTACAATATGTCATAAAGGTTTTGCACATCCGTCCGGGCTGAAagtacACACTCGAATTCATTCCCGAGAAAAGCCTTATCTGTGCTACGAATGTGGTAAAAGGTTCAAAGGAGCGTCTGAGTTACGACAACATGTCAATAGGCATAAAGGAATAAAACGTTTTGTGTGTAATCAATGTCCTgcaaaatttgttgaaaatggTAGACTTCAAGCGCATTTAAATTCACATACgggtgAAAAACCTTATTCCTGTGATTTATGCAGttccaattttaaaacaatttatgctttaaaattacataagagAATACATACAGGAGAAAAACCTTTAGCTTGTTTGAGATGTCCTAAGAGatttttaacatCAAATCATTTAAGAAGACACAACCGAATTCACACAGGGGAAAAGCcttatGAGTGCACGTTTTGTGAACGAGCATTTTCTCAAAGTAATGATTTAGTGAAGCATTTACGATCACATGTTGGAGAAAaggtgtATCAATGTAAATTGTGCCCAAGTGCGTTTAGAttacattttgaattaaaaaaacaccAAGTAGAGCATTTCAAACAAAATGACGAATCCGctgttaataattttgaaatgtTGGATAAATTGTGCCGCGCATGCATGGCATCAGAAGATGAAGACAAGCTGTTCGAAGAATTCaatgaaaaagatgaaaattttaagcaatttattcaattaacatcaataacaattgaaaaattaaaaatttgtgaaaattgtcAAATCGAATTGTTGAATGCtattaagTTCCGATCAAAATGCATTGATTCTGATAAAAGAATTCGTGAAAATTACAACATTCCAACAACACCAAAATTCGAGGTTGATACAATAGAAGAAAGcggttcaaCAAAGAAATATGTATGCGAATATTGTGATAAATGTTTTACAAGAAATTATAGTTTAAAACGTCATTTTAAAGTTCATATTAAGGAAATTCcgaaaatttcaaatcaaagtGGAACAGATTTAGATGATAATGCTGATGAAATTGATTCAGATGAAAATTTGGCTGAATATAAAAGTGGTTTAACAGGTGGCTTAACTGCAAAATTAGAGAGTAGTGGCATTGAGTTTCTTGAATACTCAGGAtcggaaaatttattaaaaaatgtcaaaattgaaaaaattgattttaatgatGATTCAAAAGATGATGAAGAATTTGATTATAATGACGATCCAAAAGATGAGGACTTTGTTGTTgagaaagaagaagaagataatgaaaatgaaattgaagaaaatgaagataaaaaaaacttattggaCTGCAGTGAAGATATAGGAATTGAAAAACcaaatccaaaaaataaacGTAGAAATTTAACTTCATGTCCGGTTTGTAATAAAACCTTTGATCGTAAATATCGTTTAGCACGTCATTTAAATGTTCATGATCCGAAAAAACCTTATGAATGTGATTATGATCTCTGCAAAATACGTTTTCAAACAGAACATGGCTTAAAACGACATAAATTATCCCATATATTGATAGATACACCGAgtacaaaaaaagtaaatgagTTTTATCAATGTCCTGATTGTCCgaggaaatttgaaaaaatcgaATCTTTATCATCACACAGaCGTATGCACAAAAAAGGTTTATcagaagaaaaatttgaatgcaaaatttgtttaaagGTGTTCGCTAAAAGGCATTTGCTGAGAAGACATTCCGAAACGCATGAAGAAAATAAACATTGGAAATGCGAATTATGTAATAAAAGTTTTGCCCTTAAATCGAAGtttatgGAACATAATATGATATCACATCAAGGTTTAAAACCGTTTACTTGTACAACATGTCATAAAGGTTTCACACAATCGTATACATTAAAAgAACACATGCGGATTCATTCTCGAGAAAAACCTTTTCTGTGCAACGAATGTGGTAAAAGGTTTAATAATTCAAGTAATTTACGTCAGCATGTCGATAGGCATAAAGGAATAAAACGTTTTGTATGTAACCAATGTCCATCAAGGTTTGTTGATAAGGGATCTTTAAATTCGCATATGATAACGCATACtgGTGAAAAGCCTTATTTCTGTGATATATGTAGTTCCAGTTTCACTAAAGGATATTCCTTGGTAAAACATAAGAGAATACACACTGGCGAACGACCTTTTGCCTGTCCCAGTTGTCCTATGaggtttatttCATCTAATCATTTAAAAAGGCACAACCGCATACACACTGGGGAAAAACCTTATaaaTGTACATTCTGTGAACGAGCGTTTTCTCAAAGTAATGATTTAGTGAAGCATTTACGTTCACATGTTGGAGAAaagGTGTATCAATGTAAATTGTGCCCAAGTGCGTTTAGATTGCATTTTGAGTTAAGAAAACATCAACAAGAGCATTTCAAACAAAATGATGAATCGGCTGTTAATGATTTTCAAGTGATAAATTCATTGAATGCTCAGCTTTTTTTAAAAGCTGCAACTGATACTGAAAAATGTTGA
Protein Sequence
MLDKLCRACMTSEDEEDKLFEEFNEKDENFKQFIQLTSITIEKLKICENCQIELLNAIKFRSKCIDSDKRIRENYNIPTTPKFEENSSIKKKFGCQFCDKYFTRSNSLKRHYKLHTKEILKISIEIDTDLNDNSDEIENDKTEELTTKLGNDIEFLKSTESENFLKKKKIDLIDDPKDENFFVGKGHSNENEIEVNEHKKISVDCENITIEKPNPKNKRRKLTSCPVCNKTFERKYRLARHLNNVHDPKKPYECDYDLCKIRFQTEYGLKRHKLSHTPNFKKLNEFYQCPDCSSKFEKIEALSTHRLTHKKSISEEKFVCDICLKVFDKRNLLTRHSQTHEENKHWQCKVCDKCFTIKSKFVEHSKITHQVLKPFTCTICHKGFAHPSGLKVHTRIHSREKPYLCYECGKRFKGASELRQHVNRHKGIKRFVCNQCPAKFVENGRLQAHLNSHTGEKPYSCDLCSSNFKTIYALKLHKRIHTGEKPLACLRCPKRFLTSNHLRRHNRIHTGEKPYECTFCERAFSQSNDLVKHLRSHVGEKVYQCKLCPSAFRLHFELKKHQVEHFKQNDESAVNNFEMLDKLCRACMASEDEDKLFEEFNEKDENFKQFIQLTSITIEKLKICENCQIELLNAIKFRSKCIDSDKRIRENYNIPTTPKFEVDTIEESGSTKKYVCEYCDKCFTRNYSLKRHFKVHIKEIPKISNQSGTDLDDNADEIDSDENLAEYKSGLTGGLTAKLESSGIEFLEYSGSENLLKNVKIEKIDFNDDSKDDEEFDYNDDPKDEDFVVEKEEEDNENEIEENEDKKNLLDCSEDIGIEKPNPKNKRRNLTSCPVCNKTFDRKYRLARHLNVHDPKKPYECDYDLCKIRFQTEHGLKRHKLSHILIDTPSTKKVNEFYQCPDCPRKFEKIESLSSHRRMHKKGLSEEKFECKICLKVFAKRHLLRRHSETHEENKHWKCELCNKSFALKSKFMEHNMISHQGLKPFTCTTCHKGFTQSYTLKEHMRIHSREKPFLCNECGKRFNNSSNLRQHVDRHKGIKRFVCNQCPSRFVDKGSLNSHMITHTGEKPYFCDICSSSFTKGYSLVKHKRIHTGERPFACPSCPMRFISSNHLKRHNRIHTGEKPYKCTFCERAFSQSNDLVKHLRSHVGEKVYQCKLCPSAFRLHFELRKHQQEHFKQNDESAVNDFQVINSLNAQLFLKAATDTEKC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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