Hvit028546.1
Basic Information
- Insect
- Horisme vitalbata
- Gene Symbol
- ZEB2
- Assembly
- GCA_951804965.1
- Location
- OX638108.1:720246-724979[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 24 2.5 2e+02 3.6 0.3 1 20 111 130 111 132 0.88 2 24 0.0051 0.4 12.1 0.3 3 23 190 211 189 211 0.95 3 24 0.077 6 8.4 4.6 3 22 216 235 214 235 0.94 4 24 0.0073 0.57 11.6 0.2 1 23 244 267 244 267 0.93 5 24 0.0012 0.091 14.1 5.2 1 23 273 295 273 295 0.97 6 24 0.00084 0.065 14.6 0.7 1 23 302 326 302 326 0.97 7 24 0.00087 0.068 14.5 0.1 1 21 446 466 446 467 0.93 8 24 1.9 1.5e+02 4.0 1.9 1 23 497 520 497 520 0.97 9 24 9.9e-05 0.0077 17.5 0.8 1 23 525 547 525 547 0.98 10 24 0.041 3.2 9.3 6.0 1 21 550 570 550 571 0.92 11 24 0.0013 0.1 14.0 0.2 1 23 583 606 583 606 0.95 12 24 7.9e-06 0.00062 20.9 1.7 1 23 612 634 612 634 0.99 13 24 6.7 5.2e+02 2.3 1.5 5 23 644 662 642 662 0.95 14 24 0.014 1.1 10.7 0.9 1 23 668 691 668 691 0.98 15 24 0.00013 0.0098 17.1 2.7 2 21 817 836 816 837 0.94 16 24 0.098 7.7 8.0 0.0 2 23 843 865 842 865 0.93 17 24 0.58 45 5.6 0.3 3 19 872 888 871 893 0.89 18 24 2.8e-05 0.0022 19.2 0.5 2 23 899 920 898 920 0.95 19 24 0.11 8.7 7.9 2.0 2 20 924 942 923 944 0.93 20 24 0.037 2.9 9.4 3.7 1 23 970 993 970 993 0.95 21 24 0.0028 0.22 12.9 2.2 1 23 999 1021 999 1021 0.96 22 24 0.064 5 8.6 0.2 1 23 1027 1049 1027 1049 0.98 23 24 0.018 1.4 10.4 0.1 1 23 1055 1078 1055 1078 0.94 24 24 0.0037 0.29 12.5 0.9 1 23 1084 1106 1084 1107 0.95
Sequence Information
- Coding Sequence
- ATGCAAGATACACAAACTCCTCGGACACCGCAGCAAATATGCCATCAATGTACTTCACACGTCACAACCTTTTTGCCTTTCTTGAAACTGTGCAAAGAATCCGCCGCGAAGTGGAACTTTCTATCCGAGTACTTGATCAACGTACCTGCTCGCACGAAATCCACAACAGCATTCATCTTTGTCACCGACAGTGTCCAAACAGTGATGGAGGAGAGTAAGAAAAACGACTTGAGAAACGTTAACACTCGTATAAATCATATTTGGGACGAGTTAAAAGCGAACCAGAAATCTTTTAAAGAACTCGAGATAAAAGAACCACGAAAAGTCTCCTACACCTGCTTAGAATGCGGTTCAAGATACAGAGAGGTGTACAAGATAAATCACCACCTGGCTAACCAGAACAAACGTCTTTGCAGACACTGTTACAAAATTGTTGATCTAAAAACTTTTTCGGAACACTTACGGACGCATTCGGTTATTTTCTTCCAATGCGAGGTTTGCTTGCTGCCTTTTGAGTGTAAGAAGAAGTTAGATTTCCACAGAAAAGTGcataaagaaagaaatatgTGCGGATATTGCAAAAAATCATTCCCTACACCAGATATACTAACTCTACACGTTCAAAGAAGACACCAGCCAGATTTCTGTCGTAACTGCAACAAGAAATTCTCTAATAGAATATGCCTGTATAATCATAGAAGAAAATGCAAGCCGATACTACCGAAGCAATACATCTGCGATTACTGCTCGAAGGAATTCAACGATAAAGGCGTTATAAAGTCTCACATAACATTGATCCATTCAAAGAAATTAATGCACCAGTGTGAGTTATGTGGAAAAAAGTTCAACAGTGCATGTCATTTAGAAGAGCATAATGAGACACATAATGTTGTAAAGGACAGATATGTTTGTCAATATTGTGACGGCAAAATATTTAGCTCCTCAGGGGGGTATCGAAGGCATTTGAGATTAAAACATTACAGAATTAATCCAGAATTGAAGGAAGAATCAAATTATTTGTGTGATGTCTGTGATAGACTCTTTGTTGATGAAGACCCCATACTCCCGCCGGGCCTATGCCGCTTCTGCGCGGAAGACGTCATTACCTCCGCTAAATTTAAACACCTTAGCGAGAAGTCAGCCCAAAGATGGAGCGAGGCAGCAGCTTCCCTTGCGGTTATACACCCAGAAGACGAAGACAAAACTATCTTCTATATGTACGAGTTAAATGACACAATTGTATGCAAAAAGAGAGTTCAATCTGTTCAATCTGCAGTCACCAGCCTGGAATCCCACAAAGTGCAGAGTTTGATAAAAGTGAACAGAAATGTATCGTACCTTTGCCCGTATTGCGATAAGCCATTTTCTAATGTTGATGTCTTGAACGAACATTTGAAGAATGGGCAGAAGAGAATGTGCAAATGTGGTCTCGTAATGGACAAATCTGAGATGTGCAAGCATTTGCTCGATATGCATAACATTTACGTATTCGAATGCAAGTTTTGCCACGATCAATTCAATAGCGACGGCGACGCAAATTGGCATCTAAAGAGGTACCACGGTCCTAACTCGTTCTCTTGTAAGAATTGCGGGCGGGGGTATAGAAACGAGAGGGGCTTGCGGGCGCATTACAACTCCCATTCGCTGTTCTTCTGTTACACATGCGGCCGAAGCTTCGAGAACAATAGCTGTTACAAACATCACACGACCACCTGCAAACCCGAGCTCAAATCAGACTTCAGTGTTTACGAATGCAATGAATGCGGACTGCAATACGACAAGAAACCGTCTCTAACGATACACATAATCCAAAAACATATGAACGTACTACCTTACGTTTGCACGATCTGCGGAAAGCGTACTTCCACGATAACTCACTTACGGTCTCATCTTAGAGTTCACGACAAACATAGGAAAACGCTGGAATGCCACTGCGGGGCTAAGTTCCGTACAGAGTTAGGTTATAGCCTCCACAAGAGATTGCATAGCGGTATCAAACCCTACAAATGCCCAGAGTGCGAAGATTCATTTATATCGTCGTCTCGGCGCTTGGATCACATGAAGAGACGTCATAAGAGTACTAAGGACATGGCACATGGATGTGACCAGTGCCCAGCCCGCTTCATAAAAGAAGATAGCTTATGCCCAAAAGGTATGTGCGCGGAGTGCGCTAGCGCCGCCCTCGCGGCCGAAGAGTTCCGATTATTCGTGCACAAAGCTCAGATTATCTGGAGTCGTGCTGTACACAACCTCAAACAACTATCTGAAGAGACCTCTGACGATGCGACATCCGTCTGCGCATTCATGTCTCAAAAGGATTCCAAGTTCAATATCGTTAAGGATTCCGGTACCGGCAGCCCGATAGAGGTTGTCAACAGATCTAAGGCGAAGATAAAGGCGGCAAGGCAGCGCCGGAAACCTATAATATACCGCAACGGACCGATGACAACATGCCCTGACTGTCACAGGTGTTTCGCGAACCCGCATTTACTTCAACAGCATCTACAGAACAGCGATAGGAAAGATGTTTGCCTCATCTGCGGCATAGTTGTCCCGAAGGGTGCTATGCTACAGAAACATATGCAAGACGCTCATAACGAGACCACTTTATTATGCAGTTTCTGTCCTTTAGCATTCTTTTCAGAGGACGAGCTGAAAGAACACGATAAAAAAGCTCATAGATCTGGTGCGATGAGTTGCAGCGGTTGTGGGAAAACGTTCAAGCGTCTCTCATCTTACGAGAGTCACGCGGAGATGCATAAAGTCATGACTTGTAGGAAATGCGGCGTCCAATTCAATAATAGGGGCTGCTTCCGCCAGCACAGGAGTGTCTGTGAGCCGAACGCGAAACGCGACCCGAAAACAATACCGCGCATTCGTAGATCAAACAACCGCGACCCGGGACAGTACATCTGCGATTACTGCGAGAAGTGTTACAACTGCCGGCAGCAACTCCAAAACCATATCCTGTGGATACATATGAATCACCGGCCGCATCAGTGCTCTTGGTGCGGTAAACGGTTTTACACAACGACGCGGCTGAACGAGCATACGGTAGTCCATACGCGAGTTAGGAAATTTGAATGTGACATCTGCGGACTCAAACTAGTCTCAAAGACCGCGGCTCTTTATCACAAACGACGGCATACGGGCGAAAAGCCTTATGTTTGTGAGGATTGCGGGGCTGCTTTTATAACAGCTTCGCGTAGGTTAGAACATGAGAAGAGGAAGCATAATAAAGGGGTTAGGTTTCAGTGTGTGGCGTGTCCGTCTAGTTTTGTAAGGAGGCGGGAGCTTGAGAAGCATGTTGAGAGACATCACAAGGAGGTTCCGGACCCTAAGCCGGAGGTTATGACTGTCAGCTTTAGCTATGTGTCGTAG
- Protein Sequence
- MQDTQTPRTPQQICHQCTSHVTTFLPFLKLCKESAAKWNFLSEYLINVPARTKSTTAFIFVTDSVQTVMEESKKNDLRNVNTRINHIWDELKANQKSFKELEIKEPRKVSYTCLECGSRYREVYKINHHLANQNKRLCRHCYKIVDLKTFSEHLRTHSVIFFQCEVCLLPFECKKKLDFHRKVHKERNMCGYCKKSFPTPDILTLHVQRRHQPDFCRNCNKKFSNRICLYNHRRKCKPILPKQYICDYCSKEFNDKGVIKSHITLIHSKKLMHQCELCGKKFNSACHLEEHNETHNVVKDRYVCQYCDGKIFSSSGGYRRHLRLKHYRINPELKEESNYLCDVCDRLFVDEDPILPPGLCRFCAEDVITSAKFKHLSEKSAQRWSEAAASLAVIHPEDEDKTIFYMYELNDTIVCKKRVQSVQSAVTSLESHKVQSLIKVNRNVSYLCPYCDKPFSNVDVLNEHLKNGQKRMCKCGLVMDKSEMCKHLLDMHNIYVFECKFCHDQFNSDGDANWHLKRYHGPNSFSCKNCGRGYRNERGLRAHYNSHSLFFCYTCGRSFENNSCYKHHTTTCKPELKSDFSVYECNECGLQYDKKPSLTIHIIQKHMNVLPYVCTICGKRTSTITHLRSHLRVHDKHRKTLECHCGAKFRTELGYSLHKRLHSGIKPYKCPECEDSFISSSRRLDHMKRRHKSTKDMAHGCDQCPARFIKEDSLCPKGMCAECASAALAAEEFRLFVHKAQIIWSRAVHNLKQLSEETSDDATSVCAFMSQKDSKFNIVKDSGTGSPIEVVNRSKAKIKAARQRRKPIIYRNGPMTTCPDCHRCFANPHLLQQHLQNSDRKDVCLICGIVVPKGAMLQKHMQDAHNETTLLCSFCPLAFFSEDELKEHDKKAHRSGAMSCSGCGKTFKRLSSYESHAEMHKVMTCRKCGVQFNNRGCFRQHRSVCEPNAKRDPKTIPRIRRSNNRDPGQYICDYCEKCYNCRQQLQNHILWIHMNHRPHQCSWCGKRFYTTTRLNEHTVVHTRVRKFECDICGLKLVSKTAALYHKRRHTGEKPYVCEDCGAAFITASRRLEHEKRKHNKGVRFQCVACPSSFVRRRELEKHVERHHKEVPDPKPEVMTVSFSYVS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -