Basic Information

Gene Symbol
-
Assembly
GCA_951804965.1
Location
OX638102.1:15447231-15457186[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00066 0.051 14.9 2.3 1 23 141 163 141 163 0.98
2 13 3.7e-05 0.0029 18.8 4.3 1 23 167 189 167 189 0.99
3 13 0.0009 0.07 14.5 0.5 2 23 193 214 192 214 0.97
4 13 1.5e-05 0.0012 20.1 3.0 1 23 233 255 233 255 0.96
5 13 3.1e-05 0.0024 19.1 0.5 1 23 263 285 263 285 0.97
6 13 0.00013 0.0099 17.1 2.8 1 23 291 313 291 313 0.98
7 13 2.1e-05 0.0016 19.6 1.8 3 23 321 341 321 341 1.00
8 13 2e-07 1.5e-05 26.0 0.4 1 23 347 369 347 369 0.96
9 13 2.6e-05 0.002 19.3 3.4 1 23 375 397 375 397 0.96
10 13 5.2e-06 0.0004 21.5 1.2 1 23 403 425 403 425 0.98
11 13 0.11 8.7 7.9 5.6 3 23 433 453 431 453 0.97
12 13 3.3e-06 0.00026 22.1 1.9 1 23 459 481 459 481 0.98
13 13 7e-05 0.0054 18.0 1.3 1 20 487 506 487 509 0.93

Sequence Information

Coding Sequence
ATGGTAGACATAGAATATTCTTGTAGAACGTGCATGAAGAGTGGTGTTAATTTAGTGAACCTAGAGGAATCGGTTAACATTGATGAGAACAGCATCATTCAATTAATTCAACTGCTGTTTGAATGTGCTGCGATACAgGCAAACAAAAAAGATGGGTTACCACAGAATCTTTGCGAAGACTGCATCCAGGTGCTCCAACAATCTTACATCTTCAAAGTCCAAGCGGCAAGAGCAGAGGAGCACTTCAAATTACTCTTGCAAGATGAGATCAAGACGGAAATCAAAGAGGAAGCTACGGAATACAATGTGTATGAAGATATCATCAATGACCATTGCTCATTCGACACAGATCTCAAATCAGAGCCAGATGAAAAACCAGAGAACATAGAAGAAATAATTCAAAAACCTGATAAGAAAATGTACTCTTGCACTATATGTGAAAAAACTTACACTAAAGAGAAGAAATATCTTAAACACTTAGAGTCGCACACTTCAAAATACAAATGTGCTTATTGTAACAAGCAGTTCGCGAAAGAAACATCATTGCAGAAGCATTTATGCACacacaatattaataaatgcaagACATGTGGCGACATGTTTAGTGACGAGACATTGTTGTTTCAACATATGGCTTCTCACAACGCAGCGACTGTCAAGGAAGAGAATGAGGAAAAAATTGAGGAAAAACCTACGCACGCATGCGATGAGTGTGATAAGACATTTACAAGTAATCGATCACTGGCACAGCATAAGAAAAAGCATAAAAAGGATAAGCCACTGAGTTATATATGTGACGTTTGTGAAAAGAAGTTTGTAACAAAGGCTCTGGTTAAACGGCATTTAAAGCTGCATGTTAAAGAGAGGCCCCACAAGTGTGGAATGTGTATAAGAAGCTATTCGAGGACCGATCAACTGAAAGTACATATGAGGACACATGTAAAGGAGAAACTTAACGGTTGTCCGTACTGTGATAAAACATTCGGACAAGTATGCAGCCTGAAAGATCACATCCGCACTCACACCGGTGAGACGCCCTACCTCTGTTCGGAGTGCGGGCGAGGGTTCGCCAACAGTTCCAACCTGAGACAACACATGCTTCGGCACACGGGGGCTAAACCACACGCCTGCAAGCTCTGCCCAAAAACATTCTGTACTAAAGGTCAAATGACAGCCCACATGGTCACCCACACAGGCGCCCACCCGTACGAATGCGACAAGTGCGGGGCCTGCTTCACGAAGCCCACGTCACTGAAGAAGCACGCCATGATACACACGGGAATTCGGCCGTATGGATGCGATACATGTCTTATGCGTTTCACATGTAAGGATCACTTGAAGCGTCACTACCGGATCCACACAGGCGAGAAGCCGTACAAGTGTCAGTATTGCGAGCGAGCATTCACTCAGAGCAATGATCTCGTCAAGCACACGCGCCAGCATCTCGGTGACAATATCTATGATTGCTCAGTCTGTAACAAGCGATTCAGATTGAAGAGTGAACTCAAGAAGCATTATCCAATACACTTCAACGACGACGGAACCATCAAGGAGCTACACGAtaaaacagacaaacaaacaaacaacaatcaATCAGAAACTTCTCTTGTACAGAACGATGTGAAGCCTATAGAAATACAATCAGAAATATATCCGCTGCCTTCGAAGGAGAATTCCAGCTCAGCTATAGCAGAAACGTCAGAAGCTCTGACAACATGCGTACCGActttagataattttatgttGCCAGATCAGATTAGCGATAACAATGATACGAAGCAAGCTAATAAATTCATGATTACTATTAATCAGGATGGCATGCTAGCTATTAATATTGAACCTGAGCCTAGGTAG
Protein Sequence
MVDIEYSCRTCMKSGVNLVNLEESVNIDENSIIQLIQLLFECAAIQANKKDGLPQNLCEDCIQVLQQSYIFKVQAARAEEHFKLLLQDEIKTEIKEEATEYNVYEDIINDHCSFDTDLKSEPDEKPENIEEIIQKPDKKMYSCTICEKTYTKEKKYLKHLESHTSKYKCAYCNKQFAKETSLQKHLCTHNINKCKTCGDMFSDETLLFQHMASHNAATVKEENEEKIEEKPTHACDECDKTFTSNRSLAQHKKKHKKDKPLSYICDVCEKKFVTKALVKRHLKLHVKERPHKCGMCIRSYSRTDQLKVHMRTHVKEKLNGCPYCDKTFGQVCSLKDHIRTHTGETPYLCSECGRGFANSSNLRQHMLRHTGAKPHACKLCPKTFCTKGQMTAHMVTHTGAHPYECDKCGACFTKPTSLKKHAMIHTGIRPYGCDTCLMRFTCKDHLKRHYRIHTGEKPYKCQYCERAFTQSNDLVKHTRQHLGDNIYDCSVCNKRFRLKSELKKHYPIHFNDDGTIKELHDKTDKQTNNNQSETSLVQNDVKPIEIQSEIYPLPSKENSSSAIAETSEALTTCVPTLDNFMLPDQISDNNDTKQANKFMITINQDGMLAINIEPEPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-