Basic Information

Insect: Horisme vitalbata
Gene Symbol: GIS1
Assembly: GCA_951804965.1
Location: OX638109.1:7338487-7343150[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 9.9e-05 0.0077 17.5 1.2 2 23 149 170 148 170 0.95

2 15 0.0065 0.51 11.8 0.3 2 23 175 196 174 196 0.94

3 15 7.6e-07 5.9e-05 24.1 1.4 1 23 202 224 202 224 0.98

4 15 0.00095 0.074 14.4 0.9 1 23 229 251 229 251 0.95

5 15 3.6e-05 0.0028 18.8 3.5 1 23 257 279 257 279 0.98

6 15 9.9e-05 0.0077 17.5 2.2 1 23 285 307 285 307 0.97

7 15 7.4e-05 0.0057 17.9 3.9 1 23 313 335 313 335 0.97

8 15 3.7e-05 0.0029 18.8 2.0 1 23 341 363 341 363 0.99

9 15 1.2 94 4.6 0.4 1 23 368 390 368 390 0.93

10 15 0.0046 0.36 12.2 3.9 3 23 408 428 407 428 0.99

11 15 4.6e-05 0.0036 18.5 1.0 1 23 434 456 434 456 0.97

12 15 7.4e-06 0.00058 21.0 1.3 2 23 463 484 462 484 0.94

13 15 1e-06 8.1e-05 23.7 0.7 1 23 490 513 490 513 0.97

14 15 0.00016 0.013 16.8 3.7 1 23 518 540 518 540 0.98

15 15 0.0007 0.055 14.8 1.1 1 20 546 565 546 567 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	9.9e-05	0.0077	17.5	1.2	2	23	149	170	148	170	0.95
2	15	0.0065	0.51	11.8	0.3	2	23	175	196	174	196	0.94
3	15	7.6e-07	5.9e-05	24.1	1.4	1	23	202	224	202	224	0.98
4	15	0.00095	0.074	14.4	0.9	1	23	229	251	229	251	0.95
5	15	3.6e-05	0.0028	18.8	3.5	1	23	257	279	257	279	0.98
6	15	9.9e-05	0.0077	17.5	2.2	1	23	285	307	285	307	0.97
7	15	7.4e-05	0.0057	17.9	3.9	1	23	313	335	313	335	0.97
8	15	3.7e-05	0.0029	18.8	2.0	1	23	341	363	341	363	0.99
9	15	1.2	94	4.6	0.4	1	23	368	390	368	390	0.93
10	15	0.0046	0.36	12.2	3.9	3	23	408	428	407	428	0.99
11	15	4.6e-05	0.0036	18.5	1.0	1	23	434	456	434	456	0.97
12	15	7.4e-06	0.00058	21.0	1.3	2	23	463	484	462	484	0.94
13	15	1e-06	8.1e-05	23.7	0.7	1	23	490	513	490	513	0.97
14	15	0.00016	0.013	16.8	3.7	1	23	518	540	518	540	0.98
15	15	0.0007	0.055	14.8	1.1	1	20	546	565	546	567	0.95

Sequence Information

Coding Sequence: ATGTTTGCCTCCAAGTGTGTATGTCGTGTATGTCTCGCCAGCGACGTCAATACACACACCATTGAGGACCCCCAACTACTTGAATTGTATGAGAAACTCATTAATGTTAAGTTCAATGCTGGTGATGGAAGGCCTACCACAGTATGCTACATATGTCGGTGCTGGCTGCTCAAGTGCAGAAGGTTCTCTGACACCGCTCGGAGGTCTGAAAAATTTCTGAGAGATCTGCTGCTCAGTAACTTgaagGTAACACCCAAAACTGTAGCTATGTTAAACATACCATCATCAAGAAACCTCACAATAACAACATTAGAACCAATATCCTTCGATGGACTAACCAACACATCCGAGGAATTAGCAAACATAGCTATTAAAGAAGAAATAGACGAACAAGAATCAAAAGTAGAGATCAAAGATAACCAAATCAAAGCAGAGAAGTTATGCAATTGTGAAGAATGTGGACTCAAATTTGCTAATAAGAAATTATTCATCGCACATCTCAAAATACATAACAAACAGACATACTGTAAGCCTTGCGATAAGATGTTTGCGTCAATAAGTTCTTTAAAAGGTCATTTAACTATTCACACCGGAGAGAAACCTTTTTCTTGTCACATTTGTGGCAAGGAGTTTAGAAAGAAACCTTACTTAGCAGAGCATATAAGAATGCATGCCGAGAAACCTCATTTCTGTTCCACTTGCAATATAGGTTTCGTTAAACCGGAAACTTTAAGCAAACATATGATTTTACACAGCAAAGACAAGCCTTATTCATGTAGCAATTGCAGCAAGAGCTTTCACTTTCAAAGCGCTTTGGATAGACATATGAAGATTCATAAAAGCGATAAGCCATTCGCTTGCAACCGATGTGATATGTCATTTCGAGTCCGCTGCGGATTAACCAAACATATGCAAGTCCATACGAATGTCAAACCACATGTTTGTGTTAAGTGTAACAAGGCTTTCAGACACGCGGTGAGCTTGAGACGCCattcaaacacacacacaaacgaaGCTAGCTATGAATGCAGCGAATGTCATAGTAAATTTAGCAACGAATCCAGCTTAGATTCTCATATGTTGACACATACAGACAAACCATTCGTTTGCGGCAAATGTAGCTCAACTTTTGGTTTATACAGCATTTATATCAAACATATGCAAGCACATAAAGAGATTGATGCTACAAATGAAGCTGTTAGGAAGAAAAATCAACCGTTATGCCCCGTTTGCAATAAGAAGCAGCACAGCAAGTCCCATCTGATCTCTCATATGAGAATTCATACTGGGGAACGGCCATTTGCCTGTGATGTTTGTCAAAGAACATTCAGAACAAAGGCATTTCTAATCGGTCATAAACGAACGCACACAGGTGAAAAAGTTTGCTCTTGTGAGATCTGTGGACAGTCATTTACTCAAACGGGGAGTTTAAACAAACATATGGTGTTACATACTGGTAAATTACCTTACGCTTGCCATTTGTGTGATAAAGCTTATAAGCAAAGTGGGCAGTTGACAGCGCATATAAGAAATTTACATGATGGTGTGAGATTCTCTTGTGATATTTGCAGTTCCAGGTTTACGGCAAAGCAGCATTTGAAGCGTCATATGAATTCTCATGCTGGTTTGAAACCGTACCCTTGTTTGAAATGTAACCAGAAGTTTTCGACTAAAACTTCAGCGAAACGGCATATGACGAATTCGTGTAAATAA
Protein Sequence: MFASKCVCRVCLASDVNTHTIEDPQLLELYEKLINVKFNAGDGRPTTVCYICRCWLLKCRRFSDTARRSEKFLRDLLLSNLKVTPKTVAMLNIPSSRNLTITTLEPISFDGLTNTSEELANIAIKEEIDEQESKVEIKDNQIKAEKLCNCEECGLKFANKKLFIAHLKIHNKQTYCKPCDKMFASISSLKGHLTIHTGEKPFSCHICGKEFRKKPYLAEHIRMHAEKPHFCSTCNIGFVKPETLSKHMILHSKDKPYSCSNCSKSFHFQSALDRHMKIHKSDKPFACNRCDMSFRVRCGLTKHMQVHTNVKPHVCVKCNKAFRHAVSLRRHSNTHTNEASYECSECHSKFSNESSLDSHMLTHTDKPFVCGKCSSTFGLYSIYIKHMQAHKEIDATNEAVRKKNQPLCPVCNKKQHSKSHLISHMRIHTGERPFACDVCQRTFRTKAFLIGHKRTHTGEKVCSCEICGQSFTQTGSLNKHMVLHTGKLPYACHLCDKAYKQSGQLTAHIRNLHDGVRFSCDICSSRFTAKQHLKRHMNSHAGLKPYPCLKCNQKFSTKTSAKRHMTNSCK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -