Hamb024486.1
Basic Information
- Insect
- Hoplodrina ambigua
- Gene Symbol
- ZNF131
- Assembly
- GCA_949774945.1
- Location
- OX458994.1:3065367-3079125[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.85 63 4.9 0.2 1 23 267 290 267 290 0.94 2 9 0.0035 0.26 12.4 1.4 1 23 396 419 396 419 0.96 3 9 7.3e-05 0.0054 17.7 3.2 2 23 424 445 423 445 0.97 4 9 0.095 7 7.9 1.5 2 23 453 473 453 473 0.97 5 9 2.4e-05 0.0018 19.2 1.3 1 21 479 499 479 504 0.94 6 9 0.00066 0.049 14.7 0.3 1 23 512 535 512 535 0.94 7 9 0.00094 0.069 14.2 0.1 1 23 541 564 541 564 0.97 8 9 6.2e-06 0.00046 21.1 0.5 1 23 574 596 574 596 0.94 9 9 5e-05 0.0037 18.2 1.4 2 23 603 625 602 625 0.96
Sequence Information
- Coding Sequence
- ATGGAGCAGGACGTGGATACAGGGTTTAGGACGGTATGCAGTGCTTGTTTGAGTAGCGATCGAGATCTTTTTGATTTGAATAACTCACCACAAGTTTATCAAGTATTTCGTTTGCTGATGTACGATTTCGCGGGCAACCGGtttggAGAGTCAGCACTGAAGATGGAACAGCTAGTTTGCTGGGAGTGCCTGGCCCTGATGAAGAGGTTCCACAAGTTCAAATGGCAAGTGCACAGCGCACAGGAGCACTTGAGAGTGCTGGCACTTAGCAGGTCTCAGGAGAGCATGGACCACACATATATGTCTCAGTCGCTGTCCTGCTTAGAAATGGAAACGAAAATGGAGTACGACAAGATTTACTTCGACTTCTCATCAGCTCCGGAAGACCAGGGGTACATAATAAGCTCTCACTCACACAACGTTAAGAGTGAACATTATGACGTGGCTCAAGTCGTCAGAGACAACAATATACTGGATATTGATGACCATATCTTGGAAGTGCCGGAGATTGTACtggaaaacccagtaactggggtGATGTCTCACATAGTGGTTGCAACTGATCCCTTGGCGTCCTCTGAACCAATGACTCATTCTGTCAATGGGTCTATGCCACATCTTACTATTGGGCCACTGATGTCATCCAAAATTGAGACAGTTATTAGGTGTCAAAATACGAATCCGAAGGTCGAGAATCCCGCAGCAAAATTAGGATATATTACAGAGTATATGAGTGAAACGGATATGCTGGCTTGCAGAGAAGAGGCTAAGCAAAAAGTCCAGTACGCTAGCTCTGTGTACAAGTGTGAACTCTGTATCATTGGCTTCTATACACAACAGCAAGTAGAAGATCATTTTCTGTCTGCGCACAAAGCGAAACCGGGTCAAGTAGCGTGCAAGGTGTGTTATATTTACGTAGATGAGAGCAAATTACCTACACATACAGACGCACACTATCTGCGCTACATCTGCAAGCTGTGCGCCCACAGCGAAATGAGCAACAAGTTGATCAGACAGCATGTGCACGCGCATATGAGTAAGCAGACCAACAATTCGAGTATTAAAATTGGAGATGTTCGTACTAAAAAGGgtagaaaaaagaaagataaagaaAAGGAGAGCGTTTCGACCCCTACTAAACCTGGTGATCTTCGGAAGCTGCTGTCTAAGACATCCATTGAAGGATACCAGTGTCTCGAGTGTGATATGTTCTTCAAAAACTCCCGCGCACGTAAGAACCACGTGGCCCGCTTCCACAGAGAAGGTCTGCAGTGTGACCATTGCAAAAAACGTTTCGTTAACAGGACTACATTAGCAACACATCTCAAGCTTCACGAAGGCCCATTGCCCCGGGCAGAATGTACGATTTGTCACAAAATGGTTCGCGTCATACAACTCAAGTACCACATACAGCGACATCAGAACAAAAGTCGATACGAGTGCGAGGATTGTAATAAAACGTTCTCGCACCTCGCGACCTACCAGGCACATCTCAAGTACTCGAGAGCGCATGCGTCGGATCAAGTGTTCAAGTTTCCATGTCCAATGTGCAATAAAGGCTACCCAACTAAAGATGCGATGCAAGATCATTTTAACTACCAACATCTCGGCAAGACTGTGCACAAATGTCCTGTTTGTGAGAAGccCATAGCGTCAAAAGCGAATGTAGAGAAGCACGTAATGAGAGTCCATGGACAGAAGAAGGAAAAGCCGAGAAACCACGTCTGTCAGGAGTGTGGCAAGGCGTTTACTGATAAGAAAGCCTTAACACAACACGAAGTAATCCACTCCGGTGAGCGCCCCCTCTCCTGCGACATATGCCAACAGACGTTCAAGCAAAAAGCGTCCTTATATACACACAGGAAGCGCGTACACAAAGTGTTCCCAGCGAAACGACTCGTCGAATATATGGATGATAGTATTCAACGCTGTAAAGTTGAGAGAATTATCGTGTAA
- Protein Sequence
- MEQDVDTGFRTVCSACLSSDRDLFDLNNSPQVYQVFRLLMYDFAGNRFGESALKMEQLVCWECLALMKRFHKFKWQVHSAQEHLRVLALSRSQESMDHTYMSQSLSCLEMETKMEYDKIYFDFSSAPEDQGYIISSHSHNVKSEHYDVAQVVRDNNILDIDDHILEVPEIVLENPVTGVMSHIVVATDPLASSEPMTHSVNGSMPHLTIGPLMSSKIETVIRCQNTNPKVENPAAKLGYITEYMSETDMLACREEAKQKVQYASSVYKCELCIIGFYTQQQVEDHFLSAHKAKPGQVACKVCYIYVDESKLPTHTDAHYLRYICKLCAHSEMSNKLIRQHVHAHMSKQTNNSSIKIGDVRTKKGRKKKDKEKESVSTPTKPGDLRKLLSKTSIEGYQCLECDMFFKNSRARKNHVARFHREGLQCDHCKKRFVNRTTLATHLKLHEGPLPRAECTICHKMVRVIQLKYHIQRHQNKSRYECEDCNKTFSHLATYQAHLKYSRAHASDQVFKFPCPMCNKGYPTKDAMQDHFNYQHLGKTVHKCPVCEKPIASKANVEKHVMRVHGQKKEKPRNHVCQECGKAFTDKKALTQHEVIHSGERPLSCDICQQTFKQKASLYTHRKRVHKVFPAKRLVEYMDDSIQRCKVERIIV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00039201;
- 90% Identity
- iTF_00124626;
- 80% Identity
- -