Hamb023014.1
Basic Information
- Insect
- Hoplodrina ambigua
- Gene Symbol
- Zfy1
- Assembly
- GCA_949774945.1
- Location
- OX458990.1:7932913-7935703[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.0027 0.2 12.8 5.9 1 23 158 181 158 181 0.97 2 17 0.00031 0.023 15.7 0.9 1 23 190 213 190 213 0.96 3 17 0.019 1.4 10.1 0.7 2 23 226 248 226 248 0.97 4 17 0.00048 0.035 15.1 0.6 1 23 257 280 257 280 0.96 5 17 0.00063 0.046 14.8 3.7 1 23 292 315 292 316 0.96 6 17 0.00015 0.011 16.7 0.7 2 23 344 366 343 366 0.97 7 17 0.0014 0.11 13.6 1.2 2 23 376 398 375 398 0.96 8 17 0.093 6.9 7.9 1.4 3 19 404 420 402 423 0.92 9 17 0.00062 0.046 14.8 0.5 2 21 428 447 427 450 0.94 10 17 0.11 8.3 7.7 1.9 3 23 460 481 459 481 0.93 11 17 0.00082 0.061 14.4 3.5 1 23 486 509 486 509 0.94 12 17 0.00053 0.039 15.0 2.1 2 23 521 543 520 543 0.96 13 17 0.18 13 7.0 0.4 1 23 570 593 570 593 0.92 14 17 1.7 1.3e+02 4.0 0.1 2 23 600 621 599 621 0.87 15 17 0.045 3.3 8.9 3.1 3 23 628 648 626 648 0.96 16 17 0.02 1.5 10.0 0.1 1 23 714 736 714 736 0.97 17 17 0.087 6.5 8.0 1.9 1 23 742 765 742 765 0.97
Sequence Information
- Coding Sequence
- atGGATCCAGATGTTAAGGTTAAAATAGAAGTTTCTGATACAAGAAAAGATCCTACCTCATTTTTACCCGAAGAGCCTATGACTTATGAaattaagaagaaaaagaagaagaagaaaaagaagcaGATAGATCCATTCAAAGATATTGATGAGAAAATGGATGTGAAGATTGAACCAATAACTTTATTGGATCCGGAGGTCAAAATAAAGGTCGAAGATATTGAAGTTGAATTGGATTTTAATGATTTTGGAGACAACAGTGGCCTGATCGAAGATCCTAACAACGAGAACGGCCAAGAACCAGCTGTGAAGACAGAGCCACAGAACCGTGATGCCGTCCTGCTCACATTTGAAAGCGTCATCAGCGAAAAATCAGGTGTCGCTAACAGCAGCGAAATGTTTGCATTCAGCAATGAAAAATTTAGCAATGAGAAATTCAAAACCGTGCTGCCATCCAAGCTAGCCCCGGCACACGTCTGCAAAGTCTGCCATTTAGTCTTTCAATCACAAAAAACTCTACGGATGCATCAAAAACGGAAACACAAGTCCTTCAGAAAGTCCTTTAAACATATTTGTGATTACTGCGGCATGTCCTATGAAATGAAGAACAGTTTAGTGGCACATATTAAGAGGAAACACGGACCAGACTCGAGACCAGATGATAGAGAAGAACGGACTTGTGAAATATGTGCTCTAGTGTTTAAAGGCATGACTCGGTTACGCATGCACATGAGACGAAAGCATGGCTCATTCCAGGACTCTTTCAAACACGTTTGCCCAGACTGTGGCTTGACTTATGACAAATACAGAAGTCTAATAGTCCATGTACAACGTAAACATTCAAATCATCAGAAACCTGAACTCAGTCAATGGTACAACTGCCCGTTCTGtcccaaaatatttacaaaaagggAAACTTACTCCCGACACGTGCAGAGAAAACATCATGTGTCAGACGAGAATATAAAGCAAGAAAAAGTCCCAGAAAATGGTTTGGAAAGTTGTAAAAATGAGGAAACTGGTGAGATAACATGTAAAGAATGCCCTCTAGTCTTTTCAtctattaactttttaaaacttcaCATGAGAAGGAAGCATAATGCGTTAAAAGAAGACTTCAGATTGAAATGTCGCATCTGCAATTTGTCTTACGATAAAATCGAGAGTTTGAAGAGACATGTGAGGAGAAAACACGACAAAGGATCTCATTGCGACGTgtgcaataaacaatttgatacGCGAGAGATGTATCTCAACCATTCACACATGAAAGCAATAAAAGAGTGCAATATCTGCGGACTTATCTTCGCATCACAAGGGGGTTTAGCAAAACATTTGCGGTGCACACACAAAATTGACTCCCCCAAAACTGTGTTCTGCAATATATGTAACGAAGGTTTTCATGATAAACGTCAATTAAAACCGCATTTCATGAAAGTGCATTTAAAAGTATCTTACACTTGTAGGTactgcaaaaagatttttaaagcGAAAGAGAGTTATCGACGGCACATATTATTTAAGCACCCGACCGGGAACCATTTTAACATTCAAGCGCAAAAATGTGAACAATGCAGTGCGACTTTTAAGGACGAATTTGAACTCTGTCGACATATAAATGTGTTTCACGGTCGCCCTGAAGATATGACAAAGGAAGACAAAGAAATAATGGAGATAAAACGAGAAGAGCCCGACATCAAGGACTGTTTCCAATGTACAAAGTGCCCGGATACATACTTGACGTGGGAACAGTTGAAATTACATTACGAAGCGAATCACCACAACATTGAAGAGACACAATGCCAGATGTGTGGGGAGATACTCCCTGGAAACGAATTACAGAAACACATAAAAAATCTACACACAGACACTGAAATGCACTGTAAATACTGTGATTTTAAAACGAATATTAGAGTAAGTTTAACTCAACATATGTTGAGGCATAAAAATGCTGAAACAATGCACTGTGACTACACCGGTTGCAAATATAAGACGTTCTACGATGGTGCTATGGAGAAGCACAAGAGAAAACACGCTGATCAAGGAGTCAAACTCCAATGTTCACATTGCCCGTTCCAAACGATGAACAAGTACATATTGAAATATCATGAAGAAGCCCATGAAACGGGGAAAAAACGTTATATGTGTGATCAATGTGATTACGCGACGATATTGCCAGCAAATCTGGTGCAACACAAGTATAAGCATTCAACGGAGAAGAGGTTTAAATGTGAAGTGTGTCCGTTCGCAACGAAATATAATACATCACTGAGATTCCATGTCAGGAAAAAACACTGTGATCTACCCACATTcagttaa
- Protein Sequence
- MDPDVKVKIEVSDTRKDPTSFLPEEPMTYEIKKKKKKKKKKQIDPFKDIDEKMDVKIEPITLLDPEVKIKVEDIEVELDFNDFGDNSGLIEDPNNENGQEPAVKTEPQNRDAVLLTFESVISEKSGVANSSEMFAFSNEKFSNEKFKTVLPSKLAPAHVCKVCHLVFQSQKTLRMHQKRKHKSFRKSFKHICDYCGMSYEMKNSLVAHIKRKHGPDSRPDDREERTCEICALVFKGMTRLRMHMRRKHGSFQDSFKHVCPDCGLTYDKYRSLIVHVQRKHSNHQKPELSQWYNCPFCPKIFTKRETYSRHVQRKHHVSDENIKQEKVPENGLESCKNEETGEITCKECPLVFSSINFLKLHMRRKHNALKEDFRLKCRICNLSYDKIESLKRHVRRKHDKGSHCDVCNKQFDTREMYLNHSHMKAIKECNICGLIFASQGGLAKHLRCTHKIDSPKTVFCNICNEGFHDKRQLKPHFMKVHLKVSYTCRYCKKIFKAKESYRRHILFKHPTGNHFNIQAQKCEQCSATFKDEFELCRHINVFHGRPEDMTKEDKEIMEIKREEPDIKDCFQCTKCPDTYLTWEQLKLHYEANHHNIEETQCQMCGEILPGNELQKHIKNLHTDTEMHCKYCDFKTNIRVSLTQHMLRHKNAETMHCDYTGCKYKTFYDGAMEKHKRKHADQGVKLQCSHCPFQTMNKYILKYHEEAHETGKKRYMCDQCDYATILPANLVQHKYKHSTEKRFKCEVCPFATKYNTSLRFHVRKKHCDLPTFS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00327297;
- 90% Identity
- iTF_00274663;
- 80% Identity
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