Hpla006568.1
Basic Information
- Insect
- Hololepta plana
- Gene Symbol
- L
- Assembly
- GCA_963695495.1
- Location
- OY968835.1:9714112-9722703[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.00072 0.061 13.5 1.6 1 23 47 69 47 69 0.98 2 20 0.0059 0.5 10.6 6.1 1 23 75 97 75 97 0.98 3 20 7.9e-07 6.6e-05 22.8 2.8 1 23 103 125 103 125 0.99 4 20 0.00028 0.024 14.8 1.2 1 23 131 153 131 153 0.98 5 20 0.084 7.1 7.0 0.5 2 23 183 205 182 205 0.89 6 20 0.44 37 4.7 1.0 5 23 231 250 228 250 0.91 7 20 0.0017 0.14 12.4 0.6 1 23 285 308 285 308 0.96 8 20 0.13 11 6.4 1.1 2 23 364 385 363 385 0.95 9 20 0.016 1.4 9.2 0.0 3 23 406 426 405 426 0.95 10 20 0.039 3.2 8.1 8.1 3 23 436 457 434 457 0.91 11 20 0.00093 0.079 13.1 1.0 1 23 462 485 462 485 0.98 12 20 0.4 34 4.9 0.2 2 12 556 566 555 578 0.86 13 20 4.9 4.2e+02 1.4 2.4 1 9 638 646 638 661 0.76 14 20 0.02 1.7 8.9 2.7 2 23 673 695 672 695 0.97 15 20 0.052 4.4 7.6 2.0 1 23 703 725 703 725 0.95 16 20 1.8 1.5e+02 2.8 0.4 3 23 734 754 733 754 0.95 17 20 9.1 7.6e+02 0.6 0.2 3 14 806 817 805 820 0.86 18 20 0.55 46 4.4 0.0 3 23 884 904 883 904 0.96 19 20 0.14 12 6.3 1.1 3 19 913 929 911 933 0.89 20 20 0.00054 0.045 13.9 0.6 1 19 940 958 940 960 0.97
Sequence Information
- Coding Sequence
- ATGATGTTCAAAGTGCCCGGAAGTTCGCCATCAAGTGTGGAACAATCGTCGCCTTCGAGCTCTTGCGTAAGTTCGTCCGCAGGCGAACAGAATGATGGTGACGAGCAATTGACGCCAGGATCATCGAGTGCGCCTACATTCGAATGTCCCCATTGTAAAATCGTTTGCGGTAATACTAACGAATTAATGAAACACATAACGGTGCATGTAAATCTTCCACGTTACACTTGCCCTTATTGTACGCGATATTTCAAACATAAAAGATCGAGAGATAGACACTTGAAGCTTCATACCGGCGACAAAAACTACAAATGCAACCATTGCGACGCGGCGTTCGCTCGGAGCGATCACCTGAAAATCCATGTGAAAACTCACGAGAATAAGAAGCCGTATCAATGCGATACATGCAGCAGAAGCTACAATACGGCGATTGCGTTAGCAACGCATCAGCAACACCACGCGGCAAAAGAACAGGACCACGGCAGCGGCAGCGGCAGCGGCAGCGGCCCGGCCGTCGCTGCCGCTCACGGCACGCCGTCGGAATCTCGCTGCTTGCAGTGTTCCGAAGTGTTTCCTACAAGCACTGAATTACAGTGCCACATAATAGACGTGCACGCGCGTCTTGAAAGGGATGACGACCAAAGGAAGAGCGTCAAAAAGATGATCGTGCTTCCCAAGATCGCGTGCATTTATTGCAGCCGTCCTTGTTCGTCCTTGTCGCATATGTACGAACATATTAACGCCGAACATGCTAACCGAATTGCAACGGTGCCGCGTAATTACCAAATAAACATGGCAGGTGTACCGCAAAACTACGAAGACACAATGCGAATATTAATCGATCCGCCGACTTACGCGTGCGAGAGGTGCAATCTGCATTTTGCGTCGTCGAATTTGCTGAAGGATCACGTCGATACGGTGCATTGGGCCGGCAGAATGAACAACGCGAATGTGCCACAAATGCAAGGAAACGTCAGCCGTAAACGGCGCGCAGACGGATCTATCGAGACGGTGCAAGATCCGGCACCGCCGGTACCAGAGTTGCAGAGTTTTAGCGAAAGCGTTTACGAAGCCAGCACGCGGCCGTGCATTTGCCCGTATTGCAACCAACAGCTGGCGAACTTCAATCTCTTCCTGATGCACATGGAGAATCATGTGAATTTAAATGCGGGAACCAGCAGCGCCACGGCGACGACTAATAATTATTCGCGAATTTGTCCGATATGCGGCGAGGCCGGTTCGAATACGGTGGAGTTCAGCAAGCACATATTCCTGCACACGATTGCCGCCGTTGTCGGCAAATGCTGCCACCATTGTAACAAGAGCTTTGATAACGATGATCAGTATCACAAGCATCTGATCGATGTTCACTCGCAAGCGTACTACAAGTGCACGGTTTGCAATGACACGTttgataatttaatcaatCTAAATGTGCATTTCCAAACGAAGCATACGAGTGCGTGTAACCATATGAAGTGTAATATATGCCCTGATCAGGTATTTCACGCCATAAACGCTGCCCAGGCTCATGTCGCCTTAAATCATAACACGCACCTACAAGCAAGCAGCTTAAGTCGCGTGCAACCGGTTGCAATGAACGATATGAATTACACCAATGTCTATCCAGAACATGATCCGAGATATTTATATGCGTCGCCGATACAATGCTCATACTGTTCTAGAACATTTCCAGACGACAACTCCCATTACTTGCACTTAGTTAATGAGCACGGCGACGTTCGAATGCCCGATAATTACTTATTAACTATGTCTTCGTCAACAGCGACAGCGACAGCGACAGCAAACCAGACGCTGATTCCGTCCAATTCGTCCGGTTACTTAGCTAGTAGTGGTGCCTCGTTAGCGTCgccgaataataaaaacaaagtaaatgcgaaatcaaattattataaatgcaaTATATGTAAAAGAAGTGATATGAAGACTGAAGGTGAATTAATTGCTCACAAGAAGTTGCACCAGTCGAAGACGAAAGAAGATCCCGTTAGTTTACAGTGCGGTTATTGCCGGATACATTGTAAATCGGGCGGCGAACTAGAGACTCACATCAAAACCCGCCACGCTCGTTACAAGAACTCGAAGCACAAGTGCAATATATGCGACGCGACGTTTGCAGAATCGACAATATTGTGCGAACACAAATTGATGCACTGCAAGATAATACAAGGTAATAATTGTCTGATATGCAAAACCGTTCTTGTTGACGAACAGTTTTTCTACAATCATCAATTGCAACACGGTAACCAAGCGTCCGTAGTAGGCAAACTGAATTCTCGCCAATCACCTTTACCGGCTAATTGTATCGTTTGCAGTCAGACAATACAAACCGACACGGAAATAGCATTACACGCGAAATTCCATCTAAGTTATTTGCGGCAAAAGGACGTCATTTGCGCTAACTGCAACATAGTCTTTTTCAATAGTGACAGTACGACCATGAAGCTTGATCTCCGTATATCCGGCAAAGATTACACGGTATCGATATGTAACGATTGTGCGAGCGGTTTGAAAAACCTCTCTTTAGAAACCGTACAAGCAAATAAAGCGCGTTTGATTGCTATTGACAAGACCAATGACGATGCTCCATCAAGCAATTTGCAATCGTCGAGCGAAAACTCCTTGCTGTGTAACATATGCAAAAGCATGATGGCATCGGCAGATGATcttcaaattcatttaattgagCACAGTTTTGCAGGACAACAGCTCCATTGTTACGCTTGCGGTGCCGTGTTTACAAATGCGAAAGGTTTACGATCGCACTGTGTAATCCACGATTATAAAAGTAGACCGTACGAATGTAAGGATTGTAAAATTAGATTCAGTTTCAAAGCCGAATTAGAAAATCATAATTATTGTCATCGATGGGCTCCTCCGCAGTTAGAAACCAACGGTGATGCTAACAGCAGAAAGAATTGTTTTAGACTGTGCCCTTATTGTGCGAAACCGTATCACGAAAGTGTTTATACCGAACACGTCGATTATTGCGCAATTAAGCCAGATAACCCGATAGCACCTAATTGCGATCAGTTGGACCAATCCGACACTACCGAAAATGATAGACTAAACTTCCAGAACCCCGTCCAACATTACTTTCAACTCGTGATCCCATGTCACCATTACCACCAACACCACCAATACCGCTACCTGAACTACCTGGTGTTGAACTAA
- Protein Sequence
- MMFKVPGSSPSSVEQSSPSSSCVSSSAGEQNDGDEQLTPGSSSAPTFECPHCKIVCGNTNELMKHITVHVNLPRYTCPYCTRYFKHKRSRDRHLKLHTGDKNYKCNHCDAAFARSDHLKIHVKTHENKKPYQCDTCSRSYNTAIALATHQQHHAAKEQDHGSGSGSGSGPAVAAAHGTPSESRCLQCSEVFPTSTELQCHIIDVHARLERDDDQRKSVKKMIVLPKIACIYCSRPCSSLSHMYEHINAEHANRIATVPRNYQINMAGVPQNYEDTMRILIDPPTYACERCNLHFASSNLLKDHVDTVHWAGRMNNANVPQMQGNVSRKRRADGSIETVQDPAPPVPELQSFSESVYEASTRPCICPYCNQQLANFNLFLMHMENHVNLNAGTSSATATTNNYSRICPICGEAGSNTVEFSKHIFLHTIAAVVGKCCHHCNKSFDNDDQYHKHLIDVHSQAYYKCTVCNDTFDNLINLNVHFQTKHTSACNHMKCNICPDQVFHAINAAQAHVALNHNTHLQASSLSRVQPVAMNDMNYTNVYPEHDPRYLYASPIQCSYCSRTFPDDNSHYLHLVNEHGDVRMPDNYLLTMSSSTATATATANQTLIPSNSSGYLASSGASLASPNNKNKVNAKSNYYKCNICKRSDMKTEGELIAHKKLHQSKTKEDPVSLQCGYCRIHCKSGGELETHIKTRHARYKNSKHKCNICDATFAESTILCEHKLMHCKIIQGNNCLICKTVLVDEQFFYNHQLQHGNQASVVGKLNSRQSPLPANCIVCSQTIQTDTEIALHAKFHLSYLRQKDVICANCNIVFFNSDSTTMKLDLRISGKDYTVSICNDCASGLKNLSLETVQANKARLIAIDKTNDDAPSSNLQSSSENSLLCNICKSMMASADDLQIHLIEHSFAGQQLHCYACGAVFTNAKGLRSHCVIHDYKSRPYECKDCKIRFSFKAELENHNYCHRWAPPQLETNGDANSRKNCFRLCPYCAKPYHESVYTEHVDYCAIKPDNPIAPNCDQLDQSDTTENDRLNFQNPVQHYFQLVIPCHHYHQHHQYRYLNYLVLN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -