Hpse021619.1
Basic Information
- Gene Symbol
- zfy1_2
- Assembly
- GCA_947369225.1
- Location
- OX376312.1:20386019-20398700[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 8.4 5.4e+02 1.8 5.0 2 23 224 246 223 246 0.95 2 11 0.00036 0.023 15.5 1.4 1 23 253 275 253 275 0.96 3 11 0.74 47 5.1 9.7 1 23 279 301 279 301 0.96 4 11 4.4 2.8e+02 2.6 2.9 2 23 306 328 305 328 0.90 5 11 0.021 1.3 10.0 5.6 1 23 331 354 331 354 0.95 6 11 0.11 7.2 7.7 3.9 2 19 361 378 361 383 0.86 7 11 0.42 27 5.9 0.9 3 22 393 412 392 416 0.91 8 11 0.00061 0.039 14.8 0.6 2 23 429 451 428 451 0.95 9 11 0.37 23 6.1 2.8 1 23 457 480 457 480 0.94 10 11 1.7e-05 0.0011 19.7 0.2 3 23 491 511 490 511 0.99 11 11 0.00083 0.053 14.4 1.2 1 23 517 540 517 540 0.95
Sequence Information
- Coding Sequence
- ATGTACAACGCAGAGGAAATAAAAGTGGAATATTATAATGCGTGCAAATTGTCACTATGCCACGCTTGTCTGAGCTCCGAACGCAATTTATCGCCTCTAGGTCAACTTGCAGAAATCTACCAGAAAATCTGCGGAAATCCAATTCTAAGCTTCCCTTCGAATGTGTCGCTGTGTTGGGAATGTGTTGCCGCACTGAAAAAGATGAAACAGTTCAAAGATAAAGTTTCCAATGCCCAGAGACTGCTGACCTGCTATCACTCCAATCAGCAGGTTTTCCCACAATGCCTATCCGGCTTAAAGATTACAGAAATAGACAACGAACAAACCATACTACTAACAGAAAACGAGAAACAAACAGAAATCAAACCTATCTCAATTAAAAAAGAATTAGAACTAGACGATGACTTTGATTACTTGGACCAAAGCAACAATGAATACACGTTAATAGACGATATTAAAGAGGAGACCGGAAATTTGAGTAATAAGTTAACAAAGATTAAGAAAGAATCGACGCATAAGTCTAAAACTAGGAAGAGAGCATACAAAATGGTGATACACCCTTCGAAACCGGTTTCTGATGTGGTCGCTCAAGAAAAGTTGGATCCAAAAGATTTGGATAGCTGGCTTGAGAAGGAAAGGAATAGCAGTTATTTTAAGGGTTTGAAGCAAAAATGTGAGAAGTGCTTGTGTAAGATAAGGAAAAGAGATACGTTGGTGAAGCATAATAAGAGATATCATCTTAAGTCTATAGGCAAGTACAGCTGCAACATATGCCAGAGCTACTTCTCGAAGAAGGAGTCTTTAACGAAGCACATAGGCCAACACTACATAGTTCATCACTGTACGGAATGTGGTTACAAATGTTATTCATCTACCCACATGTACAAGCATGTGGAATCGCATCGGAAGACTGTGCAGTGCATACACTGTGATGCTTGCTATAGCAACGTCCGCAAGTTCTACAGCCACTACAAGGCGCTGCACTGCGTGTTCATCTGCGACCACTGCAACAAGAAGTGCAACACGAAACGCATCCTCATCAAGCATATGGACAGTAAACACAATGATCACGAAGCCCCCGAATGCAAGATATGCAACCAGAAGTTCAAGAACCGCCGTTCTCTACAGTGCCACAACGAGTTGAAACACGTCTCCGGGGGGGGCGAGGACGCGTTCTGCGTGCGGTGCGACCGACAGTTCAACAGCGTCATGCTGTACAGACGACATGTGCACACCAGCGCCGCGCACGCGGACGAGCGGCAGAAAATAAAGCGGGAGAAAGTGCCGTGCCCTCTCTGCGGCAACGTTTACTCTCGTAAGACATACATGATGAACCACTACCGGCACGTCCACATGAACCAGTCCAAACACTACTGCGTGGACTGCGATAAGCCGTTCCTGAACCGTACCCGGTACCTCGACCACCGGCGTTACAACCACGAGGGACAGGTCAAAGAGAAGAACAAACTGTGCAATATTTGTGGACGAGGATTCGCTGCAAACCGAACGCTAGCTAATCACATGAGGACCCATTCTGGAGAACGACCTTTCGTGTGCACCTACTGCGATTCCAAGTTCACACAGAAGCAAGCCATGCTGTCTCATATCAAGTTCATTCACCTCAAGTTCAGAAGGAAGAACTCGGAATACGTCTGTTGA
- Protein Sequence
- MYNAEEIKVEYYNACKLSLCHACLSSERNLSPLGQLAEIYQKICGNPILSFPSNVSLCWECVAALKKMKQFKDKVSNAQRLLTCYHSNQQVFPQCLSGLKITEIDNEQTILLTENEKQTEIKPISIKKELELDDDFDYLDQSNNEYTLIDDIKEETGNLSNKLTKIKKESTHKSKTRKRAYKMVIHPSKPVSDVVAQEKLDPKDLDSWLEKERNSSYFKGLKQKCEKCLCKIRKRDTLVKHNKRYHLKSIGKYSCNICQSYFSKKESLTKHIGQHYIVHHCTECGYKCYSSTHMYKHVESHRKTVQCIHCDACYSNVRKFYSHYKALHCVFICDHCNKKCNTKRILIKHMDSKHNDHEAPECKICNQKFKNRRSLQCHNELKHVSGGGEDAFCVRCDRQFNSVMLYRRHVHTSAAHADERQKIKREKVPCPLCGNVYSRKTYMMNHYRHVHMNQSKHYCVDCDKPFLNRTRYLDHRRYNHEGQVKEKNKLCNICGRGFAANRTLANHMRTHSGERPFVCTYCDSKFTQKQAMLSHIKFIHLKFRRKNSEYVC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -