Hpse008503.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_947369225.1
- Location
- OX376337.1:8132384-8137113[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.19 12 6.9 2.9 1 23 306 329 306 329 0.93 2 14 0.006 0.39 11.7 1.3 2 23 336 357 335 357 0.96 3 14 0.11 7.2 7.7 1.0 2 23 364 385 363 385 0.96 4 14 4 2.6e+02 2.8 0.0 3 21 393 411 392 412 0.91 5 14 0.053 3.4 8.7 0.1 2 23 434 456 433 456 0.95 6 14 0.46 29 5.8 0.2 2 23 463 484 462 484 0.90 7 14 0.74 47 5.1 1.0 3 23 492 512 491 512 0.94 8 14 0.00098 0.063 14.2 0.2 3 22 520 539 519 539 0.93 9 14 0.00034 0.022 15.6 1.0 2 23 588 609 587 609 0.97 10 14 0.00027 0.017 15.9 0.8 1 23 617 639 617 639 0.98 11 14 0.00012 0.0074 17.1 3.5 2 23 645 666 645 666 0.97 12 14 0.003 0.19 12.6 4.7 1 23 672 694 672 694 0.98 13 14 0.003 0.19 12.6 6.2 1 23 700 722 700 722 0.96 14 14 0.0003 0.019 15.8 3.8 1 23 728 751 728 751 0.97
Sequence Information
- Coding Sequence
- ATGGAAGATCCACTGGAAAGTGGAAACAAAACTCACTGTCGTTTTTGTGCTGAAGAAAAAAATTACGGCGAAGTACTCGATCTTCAAGGTGATATAAAAACGTTTGAAGAATATCTAAAAATCTTGGAATATCTAAAAGTCGATTACTTGGACTTGTCCGACTCGAACAGACTGCCGAAAACTACTTGCGAAAAGTGTTATGATGGTTTTCAGGAGGCCTACAAGTTTTTCACGATACTCGATCATATTCAGTCGGTTTTGAAAACATCTTATGATATTAACGTCAAAAGAGAACCCGCAGACCTTAAATCAGCTAAAAGTGAGAAGAAACACCAAGAAAATACAGAAAGTGATGTACAAAATTGTCCAGATGATTTTATTTCTGGACCGTCTCATCTAGAAAATAAAACTCAAGATTGTAAAGGTCCGAGTTCAGAGGACAATTCAAAAACTAAACCGCAATACAGTATTGCATTTAGTGATAATGATAAAAAAATATCTCAGTGCCGTTTCTGTGCTGGACACAAAAGTTCTAAAGATATGGTCCACCTATCAGGAGAGACTACGATAAAAGAGTATAGAAAAATCATGAGCTTCTTCAAAATTGGCTATTTAAATCTAGACCAGGCTAAATTGCCTAAAACATCCTGCGAACTCTGCTACAATTCTCTCCTAAAAGTCCATAAGTTTTTGAGGAACGTTAGAAATAGTCAGATCATTCTAAATAGTTTATACAATGTTAAAACGGAACCTGGGCATAATCATATAAAAATTAAAATTGATGAGTATAATAATATGGAAAGTGAAGACCTAAATATGTCTAGTACGAATACACAAGAGACAAATGTAGTACCATTATCTATACTTTCACTAAACTATTCAAGCGAAGTGGATAAATCATGGGCAAACTACTTGTATATTTGCTGTCACTGCCAAGTTGTGTACGAGAGTATGGACGAGCTCCGGTCACATAGCAAGGAGAAACACAGCATGTGCTATGCGCTCCGATGTGCAGATTGCAATGAGAAATTCTGTGGCTTTAGCGACTTCATAGAACATGTTAGGCAGCATAGAGAAGTGTTAAGACTTTACTGCCAGTACTGTAATGCACAATTCGAAACAGCAGCCCAATGCACAGACCATGTAAACACCCACTACATCGGCACTCAGAAGATCTGTGAGCTCTGTGGGGAGATGCTGCCCTACACCAACACATTGGATTGGCACAGGAAGCTGTACGGGCAACCATCAAAGGAGGTCCAAAGGGATAATGGGAAATCTTGGCTGGATTATGAGTGGGTTTGTCAGGACTGCTCCCTCACGCTGCCTGACGTGGCCAGCCTGCGCACGCACACCCAGAAGGCACACGACAAGTGTTTCGCGATGCGCTGCATGGATTGTTCCAAGGTGCTGAAGAACTTCAAGCTGTTTGTGGCCCACGCGGTGGAGCACAGGCCTTATCTCAAAAACTTCTGCCAATACTGCAACTCACACTATGACGACATAGCAGAACTCAACCAACACAGAGTGCAGCACATAACGAGCCAACAGCGGCCGTGCGCCAACTGCGGGCAGATATTCAAAGACAACACCCAACTGGCGAAACACAAGAACACTTTCAAAAACGCCACCACCAAACCAAAAACCACAGTAAAGCGAAGGAAAATCTCCACCAAACGTCGTGTCACTAAAAAATCTACAAATAAAACCACTAAACGCAAGCGCGTTGTTAGAAAAGGCTCTTTAAGCACAGAAGATCTCACTTGTACGGTGTGCCAGAAACTCTTCGATTCCCTAGCTAAGTTATCGAGACATCTCAAAACCCACGATGGCACCAGACCTCGAGATTTCGTCTGCCCGACATGTGGAAAAACATTTTTAACAAACACCACGATGAGAGATCACGCTAAAACCCATAGTGTTAGGACTGAAGTGTGCCAGGTTTGCCAAAAAGAATTTCACACGAAGCATCAATTGAAAGCCCATATCATAACACATTCTGAAGTAAGACCGTTCGTCTGTGACGAGTGTGGAAACAGTTTTAAAACGAAGAAACGTTTGAAATGTCACCTGAAAACCCATTCAAACATTAAACCGTACAAGTGTTTGTATTGTTTCAAGGAATTTAAGTTTAAGGAGAATTTGAAAACGCACGAACACCAGCACACGGGTTTGAGACCGTACTCCTGTGAGATGTGTGAGCGAACGTTCACTAATTGGACGAATTGTAACAAACATATGATTAGGAAACATGGTGTGACCCTAGCGAGGACCAAGATCACAGCGCAAGGCAGGGTAGCCATCGATAGGAAAACAGGGGAAATAAAAAGTATAGCCTCCGATAAGAAAACTAAGGATTGGTTGGATCAGATGATGAAGCCTGAGAAACGGGGCAGGAGAACTACACAGTAA
- Protein Sequence
- MEDPLESGNKTHCRFCAEEKNYGEVLDLQGDIKTFEEYLKILEYLKVDYLDLSDSNRLPKTTCEKCYDGFQEAYKFFTILDHIQSVLKTSYDINVKREPADLKSAKSEKKHQENTESDVQNCPDDFISGPSHLENKTQDCKGPSSEDNSKTKPQYSIAFSDNDKKISQCRFCAGHKSSKDMVHLSGETTIKEYRKIMSFFKIGYLNLDQAKLPKTSCELCYNSLLKVHKFLRNVRNSQIILNSLYNVKTEPGHNHIKIKIDEYNNMESEDLNMSSTNTQETNVVPLSILSLNYSSEVDKSWANYLYICCHCQVVYESMDELRSHSKEKHSMCYALRCADCNEKFCGFSDFIEHVRQHREVLRLYCQYCNAQFETAAQCTDHVNTHYIGTQKICELCGEMLPYTNTLDWHRKLYGQPSKEVQRDNGKSWLDYEWVCQDCSLTLPDVASLRTHTQKAHDKCFAMRCMDCSKVLKNFKLFVAHAVEHRPYLKNFCQYCNSHYDDIAELNQHRVQHITSQQRPCANCGQIFKDNTQLAKHKNTFKNATTKPKTTVKRRKISTKRRVTKKSTNKTTKRKRVVRKGSLSTEDLTCTVCQKLFDSLAKLSRHLKTHDGTRPRDFVCPTCGKTFLTNTTMRDHAKTHSVRTEVCQVCQKEFHTKHQLKAHIITHSEVRPFVCDECGNSFKTKKRLKCHLKTHSNIKPYKCLYCFKEFKFKENLKTHEHQHTGLRPYSCEMCERTFTNWTNCNKHMIRKHGVTLARTKITAQGRVAIDRKTGEIKSIASDKKTKDWLDQMMKPEKRGRRTTQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -