Hpse000504.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_947369225.1
- Location
- OX376336.1:5549684-5556353[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 1.2 75 4.5 1.8 3 23 53 74 52 74 0.94 2 16 0.00082 0.052 14.4 0.5 2 23 101 123 100 123 0.94 3 16 0.0048 0.31 12.0 0.1 1 23 145 167 145 167 0.96 4 16 0.02 1.3 10.1 0.1 1 23 171 194 171 194 0.90 5 16 0.58 37 5.4 0.9 2 22 200 220 199 220 0.89 6 16 0.016 1 10.3 0.1 2 23 228 250 227 250 0.89 7 16 0.02 1.3 10.0 1.2 2 21 258 277 258 280 0.83 8 16 0.0034 0.22 12.4 2.5 1 23 284 307 284 307 0.94 9 16 1.2 75 4.5 1.8 3 23 337 358 336 358 0.94 10 16 0.076 4.9 8.2 1.4 2 23 385 407 384 407 0.89 11 16 0.0051 0.33 11.9 0.1 1 23 429 451 429 451 0.96 12 16 0.02 1.3 10.1 0.1 1 23 455 478 455 478 0.90 13 16 0.11 6.9 7.7 1.3 2 22 484 504 483 504 0.88 14 16 0.0045 0.29 12.1 0.3 1 23 511 534 511 534 0.91 15 16 0.02 1.3 10.0 1.2 2 21 542 561 542 564 0.83 16 16 0.0034 0.22 12.4 2.5 1 23 568 591 568 591 0.94
Sequence Information
- Coding Sequence
- ATGTTGTTGTTTGTTTGTAATAATTCATTCATTCATACAAAACTTGTCCAAATCAGATACTTCTCTTTTCTAGACGTGGAGGAGCACAACGCCACGATTATTCTGCGACACTCCACGGCGTACCCGTTCCGGCTCAATTCCAAGTCAATAATACTCTGCTGTTACTGCCCCAACCGATACGATGACCCTTGCTTATTTAGAGCGCATGTGGATTCTGAACATCGAACAGTCGACCAACACCACGCGGCTCTACAGACAAACAAATATTGTACTCTAGTACGCGTAGATATCACCAATTTACGTTGCAAATCTTGTATCAAAGTCTTCTCTAATCTCGACAATCTTGCGAAACATTTAAAGGACGATCACGACCTCGAAATCGATTTGAATCATGGCTTCGGTGTAGTGCCAATGAAACTAGAAAAGGACCACTTTCAATGTCTTGTGTGTCCAAAGATATTCAGCGGATTACTAGAGTTGTACAAACACGCTGCCAGCCACATAGTTCGACATATTTGCGACGTTTGTGGAAAAAACTTTCAGACTGCAGCAGGTGCAATTTCTCACAAGGAATCTGTACATCCAATACAAGATGTGTACTGTAGGGCTTGCAAAAAGTCGTTCCCTTCCATTGAGGCTAGAAAGCATCACAGGAAGACTGATAAAACTTGTTTACCGGTCAAATGTACCATCTGTAACGAACGTTTTCCGTATTGGGAGGCCAGGCAGGATCACCTCGTTGAAGTGCATGGGAAAGAGAAGTTGGTGAATCGTTGTACAATGTGTGAGAAAGTGTTTAACTCTCGTACCAATTTGTATTTCCATTTCAAAGCGGAACACACTGATGATTTCAAGTGTCAGTATTGTGATCGGAGGTTTCCGACTCGGACCAGAGTGCAGGAGCATACATTCAAAGTACACACTGACGTGGAGGAGCACAACGCCACGATTATTCTGCGACACTCCACGGCGTACCCGTTCCGGCTCAATTCCAAGTCAATAATACTCTGCTGTTACTGCCCCAACCGATACGATGACCCTTGCTTATTTAGAGCGCATGTGGATTCTGAACATCGAACAGTCGACCAACACCACGCGGCTCTACAGACAAACAAATATTGTACTCTAGTACGCGTAGACATCACCAATTTGCGATGCAAATGTTGTATCAAAGTCTTCTCTAGTGTCGACAATCTTGCGAAACATTTAAAAGACGATCACGACCTCAAAATCGATTTGAATCATGGCTTCGGTGTAGTGCCAATGAAACTAGAAAAGGATCACTTTCAGTGTCTGATGTGTCCAAAGATATTCAGCGGATTACTCGAGTTGTACAAACACGCTGCCAGCCACATAGTTCGACATATTTGCGACGTTTGTGGGAAAAACTTTCAGACTGCAGCAGGTGCAATTTCTCACAAGGAATCCGTTCATCCAATACAAAATGTGTACTGTAGGGTTTGTAAAAAGTCGTTCCCGTCCATTCAGGCTAGAAAGCATCACAGGAAGACTGATAAAACTTGTTTGCCGTTCAAATGTACCATCTGTGACGAACGGTTTCCGTATTGGGAGCGCAGACAGGACCACCTCAGCGAAGTGCATGGGAAAGAGAAGTGGGTGAATCGTTGTACAATGTGTGAGAAAGTTTTTAACTCTCGTACCAATTTATATTTCCATTTCAAAGCGGAACACACTGATGATTTCAAGTGTCAGTATTGTGATCGGAGGTTTCCGACTCGGACCAGAGTGCAGGAGCATACATTCAAAGTACACACTGGTGAACGTCCGTTCATATGCACAACAATGATGCGAATCTCATCGCGAGACAGAACGCCCAGATAA
- Protein Sequence
- MLLFVCNNSFIHTKLVQIRYFSFLDVEEHNATIILRHSTAYPFRLNSKSIILCCYCPNRYDDPCLFRAHVDSEHRTVDQHHAALQTNKYCTLVRVDITNLRCKSCIKVFSNLDNLAKHLKDDHDLEIDLNHGFGVVPMKLEKDHFQCLVCPKIFSGLLELYKHAASHIVRHICDVCGKNFQTAAGAISHKESVHPIQDVYCRACKKSFPSIEARKHHRKTDKTCLPVKCTICNERFPYWEARQDHLVEVHGKEKLVNRCTMCEKVFNSRTNLYFHFKAEHTDDFKCQYCDRRFPTRTRVQEHTFKVHTDVEEHNATIILRHSTAYPFRLNSKSIILCCYCPNRYDDPCLFRAHVDSEHRTVDQHHAALQTNKYCTLVRVDITNLRCKCCIKVFSSVDNLAKHLKDDHDLKIDLNHGFGVVPMKLEKDHFQCLMCPKIFSGLLELYKHAASHIVRHICDVCGKNFQTAAGAISHKESVHPIQNVYCRVCKKSFPSIQARKHHRKTDKTCLPFKCTICDERFPYWERRQDHLSEVHGKEKWVNRCTMCEKVFNSRTNLYFHFKAEHTDDFKCQYCDRRFPTRTRVQEHTFKVHTGERPFICTTMMRISSRDRTPR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -