Hpse014314.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_947369225.1
- Location
- OX376338.1:823872-826292[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.023 1.5 9.8 1.8 1 23 99 122 99 122 0.98 2 11 7.9e-06 0.00051 20.7 1.0 1 23 126 148 126 148 0.98 3 11 2.7e-07 1.7e-05 25.4 4.2 1 23 154 176 154 176 0.98 4 11 0.0029 0.19 12.6 0.3 1 23 182 204 182 204 0.96 5 11 3.9e-05 0.0025 18.5 2.4 2 23 212 234 211 234 0.96 6 11 1.2e-05 0.00077 20.2 2.9 1 23 240 262 240 262 0.98 7 11 0.038 2.5 9.1 1.0 1 23 308 330 308 330 0.98 8 11 0.0043 0.27 12.1 5.3 1 23 336 358 336 358 0.98 9 11 2.4e-05 0.0015 19.2 0.3 1 23 364 387 364 387 0.95 10 11 0.00072 0.046 14.6 1.0 1 23 421 444 421 444 0.95 11 11 0.00051 0.032 15.1 1.5 1 23 450 473 450 473 0.95
Sequence Information
- Coding Sequence
- ATGTTACAATTATTATTACGTGACAGTTACATAAATCTGTTTCTTACAGATAATGACGTTGATTTTGATGACGCCGCCGAACCGATTAAAACTGAAGATAAAAAAACGTGCAAAATAGAAATATGTTTGGAACCCAAGTACACACCGCCGGCCAAAAAGGGCGGCGCGCGGAAAAGAACCACTAGACCTGTCAAGCAACCGGCCAAGGATAAATCTGCCAAGAAACCACCCATCAAGAGAGAAAGAACCCACCCATCCTTAGTAGTAAAAGTTAAAACCGAAAGCGGCCATCTTTACACATGCAAGGCTTGCAGTGGGAGCTATGAGTCGCTGAAGACTTTACATCTACACATCAGGACTTCGCATAAAAGATCCTACGACTGCACAATCTGCAATGAAAATTTCAACGGGGAATCCACGTTTAAAAGACACATGATGACCCATAATGAAACTTCACCGTTCCCATGCACATACTGTGATAAAAAATTTAGCAACTACCATAATTTAACCACCCATATTAACACGCACACTAAACAGAAAATTTATATCTGCGATGTGTGCAGCAAATCTTTTGCAACGAGACAGATTATTATAAAACACCTGAGATTGCACGAAGGAAAGAATAAGAAATGCATGTGTGAAATTTGCGGGCACTCGTTCAACGATAGAACTAACATGATGATCCATGTACGAACGGTGCATGAAAAGCTGAGGCCGTTTCCTTGTACGTTATGCTCGAAGACGTTCTCAGCGAAGAAACATTTGAAAGTTCATATAATGAAACACACCGGGGAACGTCCGTATCAGTGTGAATTGTGTCTCAAATCGTTCATCTGCATTACTGATTTGAAATGTCATAGAAAAAGGAGACATGGAGTCACGGGGGATCGGCCTGAAGGATATAAAGTGAACGAAGTGAGGTATCGTTGTGTAGTGTGTGGTGATAGTTTTGAAAGCCGAGGACAGCATAGAATTCATGTCAAAACGCACGCTGGACAACTGCCTTTCAAATGTAATTTCTGCCCAAAAGACTTTACGTGCAAGTATTCAATGAAAAGACACATCAATGAACACTTTGGTGTGAAACCTCACGAGTGTCCTATATGCGAGAAGAGGTTTGTTCAAAAAGATCCAATGAAGAGGCATTTGGCCATCGTACATGACCCTCAAAGGGCAACGAGATTGAAGGAACAGTGTGACATGTGTAAACTGAAAGTGTACGATTTAGAACTGCATAGAAAGATCCATTTGAAACGGCCGTATGCTTGCCATTTGTGCAGCAAAACGTACGCAGCAAACAACGGTCTGAACAGACATCTGAAGGAGTCTCACTACCAGAAGAGAGGGTTCGCTTGTGATCTGTGTGATAAGAAATATATGAAGTCTGGTACGTTGAAAAGACATAAATTAAAAATGCATAACGTGAAAACTGAAATCGATGAGTTGCCAGCGTATGCTATTAAAAATAATTATATCAGTGATACAGGGCCTCCAGTATCTGATGAAGATGAATAA
- Protein Sequence
- MLQLLLRDSYINLFLTDNDVDFDDAAEPIKTEDKKTCKIEICLEPKYTPPAKKGGARKRTTRPVKQPAKDKSAKKPPIKRERTHPSLVVKVKTESGHLYTCKACSGSYESLKTLHLHIRTSHKRSYDCTICNENFNGESTFKRHMMTHNETSPFPCTYCDKKFSNYHNLTTHINTHTKQKIYICDVCSKSFATRQIIIKHLRLHEGKNKKCMCEICGHSFNDRTNMMIHVRTVHEKLRPFPCTLCSKTFSAKKHLKVHIMKHTGERPYQCELCLKSFICITDLKCHRKRRHGVTGDRPEGYKVNEVRYRCVVCGDSFESRGQHRIHVKTHAGQLPFKCNFCPKDFTCKYSMKRHINEHFGVKPHECPICEKRFVQKDPMKRHLAIVHDPQRATRLKEQCDMCKLKVYDLELHRKIHLKRPYACHLCSKTYAANNGLNRHLKESHYQKRGFACDLCDKKYMKSGTLKRHKLKMHNVKTEIDELPAYAIKNNYISDTGPPVSDEDE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00806997;
- 90% Identity
- -
- 80% Identity
- -