Basic Information

Gene Symbol
-
Assembly
GCA_947369225.1
Location
OX376336.1:5139213-5141069[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.02 1.3 10.0 0.4 1 23 51 73 51 73 0.97
2 16 0.063 4.1 8.4 0.1 2 23 101 123 100 123 0.89
3 16 0.026 1.7 9.7 0.3 2 23 144 166 143 166 0.94
4 16 0.00047 0.03 15.1 2.0 1 23 171 193 171 194 0.92
5 16 0.016 1 10.3 1.7 1 22 198 219 198 221 0.90
6 16 0.002 0.13 13.1 2.2 3 23 225 246 223 246 0.96
7 16 1.3 86 4.3 0.1 2 19 253 270 252 273 0.93
8 16 0.00071 0.045 14.6 2.7 1 23 323 346 323 346 0.94
9 16 0.083 5.3 8.1 0.1 2 23 374 396 373 396 0.95
10 16 0.00044 0.028 15.2 0.5 3 23 420 441 418 441 0.96
11 16 6.5e-06 0.00042 21.0 1.0 2 23 447 468 446 469 0.93
12 16 0.013 0.82 10.6 5.3 1 21 474 494 474 497 0.91
13 16 6.9e-05 0.0044 17.8 0.1 2 23 503 525 503 525 0.96
14 16 0.0077 0.5 11.3 6.8 1 23 529 552 529 552 0.97
15 16 0.049 3.2 8.8 0.8 2 23 559 580 558 580 0.96
16 16 0.012 0.76 10.7 2.3 1 23 586 608 586 608 0.96

Sequence Information

Coding Sequence
ATGCTTACCAATCCTAAGGGTACACTATACAGAAGACTAAATTTCTTTTCAGATGATAATCCGGCAAAGGGTGCCAATATGCTAAGGAGGAGAAACCTGCAAATCTTGTTCAACAACACAACGATGATACCGTTTAAATGGCGCGGGAAATACATGTGTTTTTACTGTGGGGCCGATATAGATAAATATGATGATTTGAAGAAACACACAAAAGCCCACGGCATATGCACCGAAAGAGATCGGGCTATAAGATTAGTGAAATCCGGAGACGCTGAAGTGAAAATCGACGTCTCAGACATTACTTGTGAACTGTGTAACGAATCATTCCCCAATTTCGAAGAAATTGTTTCTCATTTGATATTTAAACATAAACTAGCGTATAATAAAGACGTAGAGTTAGCAATAACGGTATATCATCTTGTTGATCTCAAATGCTTACAATGTGAAGAAAGTTTTGACTTTTTGGGTAAACTAATAACGCATGTCAATAACAGTCATCCTGACAACTGTTTCTTATGCGACAGTTGCGAACAGAAGTTTAACAAAAAGAGGGATCTGCAAGCTCATATCAGAGCTCATCATAAGGAGAAGTATTACTGTCTAAAGTGCACATCAAGTTTTACCTCTCATGCGGCGCTTCAAAATCACAAAGGGAATGCCCACAGTTCTATATGCAATTTCTGTTTTAAAACCTTCTCATCGGCTACAAAACGTTTGCGACATATGAATAGGGAACATGATTTTGGTGGTCTACTCCAATGCGGACTTTGCCTTAAAGTCCTACAAACGAAGCAGTCCTTTTTACGGCATGCAGCGAACTGCAACTTAACCAACGACGACTGTAAACCAGAAGGATCCAACCTTGATGATAAGGACAACAGAACGAGCATTAAGCAGCTCAGAAGCAATATCGCTTGCATATTGAACATGTCCACCGGAATACCGTTCAAGCATTTCATGAACAGATTCAGATGTTTCTACTGCCCCAAAGACTTTACAGACTGCGATGATATGAAACAACATACTGTAATGGAACACCCGTTGTGCGATATCAAGCTAAAATGCATGAGACTGCGAAATAGAAAAGAAGAATGCATTAAAATAGACACGTCTTCGCTATCGTGCAAAATGTGTTTCGAATCTATGTCTGATCTGAATGCTTTGATAAATCATCTGATAACGGAACACAAGGCGCGATATGACAAAACGATTGCACACGTGTTTCAACCTTTTAAATTGATCAAAAATAACTATGGTTGTCCGTATTGCGGGCAGTTCTACAGCTATTTTAGTACATTACTCAAACATGTTAGCAAAGATCATACGGACAACAGGCTCATATGCTTGTATTGTGGCAAATCTTTCAGAACGGATCCTAATTTAAGAGCTCATATCACCCGTCACCATAAAGCAGCTAGGTACAAATGCACTCACTGTGAATGTGAGTTCACGTCGAGCAACGATTTGCATATGCATTTGGGAGCCAAACACGGCGTTAAGTTCGCCGAATGTCCCCAATGTCCCGAGAAATTCACGTCTCAATATTCAGTTGCTAGACATTTGATAACTGTTCATTCCACGGGACACAAGTGTTCGTTTTGCGACAAATTGTTCACTAGACACTCTTTCATGATGAACCACGTGAGGCGGTTACATTTGAAAGAGAAAAACGTCGAATGTTCCGTGTGTTTCGAACGATTTTTTGATACTCAGCGTCTGAAGATGCATATGGTGAAACATATAGGCGAAAGGAATTTTCACTGTGATATTTGTGGGAAGAAGTTTCTTTGGAAGAAGAATCTTAGAGGGCACATGTCGTCTCATATAAAACATGCTAATTCTCTTTTGCAAAACTGA
Protein Sequence
MLTNPKGTLYRRLNFFSDDNPAKGANMLRRRNLQILFNNTTMIPFKWRGKYMCFYCGADIDKYDDLKKHTKAHGICTERDRAIRLVKSGDAEVKIDVSDITCELCNESFPNFEEIVSHLIFKHKLAYNKDVELAITVYHLVDLKCLQCEESFDFLGKLITHVNNSHPDNCFLCDSCEQKFNKKRDLQAHIRAHHKEKYYCLKCTSSFTSHAALQNHKGNAHSSICNFCFKTFSSATKRLRHMNREHDFGGLLQCGLCLKVLQTKQSFLRHAANCNLTNDDCKPEGSNLDDKDNRTSIKQLRSNIACILNMSTGIPFKHFMNRFRCFYCPKDFTDCDDMKQHTVMEHPLCDIKLKCMRLRNRKEECIKIDTSSLSCKMCFESMSDLNALINHLITEHKARYDKTIAHVFQPFKLIKNNYGCPYCGQFYSYFSTLLKHVSKDHTDNRLICLYCGKSFRTDPNLRAHITRHHKAARYKCTHCECEFTSSNDLHMHLGAKHGVKFAECPQCPEKFTSQYSVARHLITVHSTGHKCSFCDKLFTRHSFMMNHVRRLHLKEKNVECSVCFERFFDTQRLKMHMVKHIGERNFHCDICGKKFLWKKNLRGHMSSHIKHANSLLQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00208139;
90% Identity
-
80% Identity
-