Hpse009350.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_947369225.1
- Location
- OX376313.1:13555697-13561695[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 6.8e-06 0.00044 20.9 1.1 2 23 148 169 147 169 0.97 2 9 0.00037 0.024 15.5 2.5 2 23 177 198 176 198 0.98 3 9 0.00031 0.02 15.7 1.4 1 23 204 226 204 226 0.97 4 9 7.9e-06 0.0005 20.7 2.3 1 23 232 254 232 254 0.96 5 9 2.7e-06 0.00017 22.2 0.2 3 23 262 282 260 282 0.97 6 9 3.5e-06 0.00023 21.8 0.5 3 23 290 310 288 310 0.97 7 9 1.3e-05 0.00084 20.0 2.3 3 23 318 338 316 338 0.98 8 9 0.0002 0.013 16.3 0.4 1 23 344 366 344 366 0.97 9 9 6.7e-05 0.0043 17.8 4.2 1 23 372 394 372 394 0.97
Sequence Information
- Coding Sequence
- ATGGCGAACACGCAGCTAGATTTCACAAAGATATGTCGTGCTTGTTTGACCGACAACGCACCGATGAAGGATTTGTTTACTGTATGTTCTCCGGACGTCTATAGATACTGCACTTCCGTTGAGGTATCTGAAGGAGACGAAATGCCTAAGCAAGTCTGTGAGGCCTGTCTGGATTTGTTAAACAAGTTCTACTACTTCAAACAAGTTGTAATACGATCAAATGCAGTTTTGAAACAACATTGTTCAGTACCGGTAAAAGTGGAAAATCAACAGGTTGAAGAAATACTAATGGTGGCATTAACAGGGGACTCGGATGAGGGGTCATCTCAGGATAACATACAGGACCAGCCAATGAATGAGGAAGCAAACAAAACAAAACCTAGGAAACGTAGAAAATATACTAGAGGTGCAGAAAAACCCAAACCGAAGAGACCACGGATGAAATGTGTTAAGTGTGAAAAAAGTTTCCAGAAATATGAGAATCTAGAGGCACACATGCGAAGTCATTTTGGTAAAAAGCCGGACATAAAATGTGACCACTGCGAAAAAACATTCCTAAACTTCCGAAGTCTCAACGCGCATGTCCGGACGCACACTGGCGTGCGCAAGTATCAATGTCAGACATGTGGAAAACACTTCGCATACCTCAACGTGTTGAAAAACCACGAGCTCATCCACTCAGGCGTTAAGAAACACGCCTGCCATATATGCGACATGAAGTTTGTTCAGGCTTACAACTTGAAGATGCACCTAGAAACCCACAGCGCGGAAAAGAACTACGGCTGCGTCCAATGTGGAAAGAAGTTTTCTCAGCCGGGCAACCTGAAGATCCATCTTATAAGGCACACGGGCATCAAGAACATAGCCTGCACTATCTGTGATATGAAGTTCTATGTTAAGAGTGATTTATACAAGCACATGCGGTCCCACTCTGAGAACAAGCCGTTCGGATGCAGCCTGTGTGACAAGACTTTCAAGAGCAAGAGCTTCCAGACTGTGCACATGAGGACCCACACCGGCGAAAGGCCCTACGCATGCGACCTGTGCCCCAAACGCTTTATGGCGCGCAAAGACCTCCGAAATCACCGCATGATCCACACCGGGGAGAAACCTCACAAATGCCAACTATGCAACCAGGCATTCATCCAAAAATGCGCCCTCAATCGTCACATGAAGGGCCACGGCAAGTCAACCGCCGACGAGACGCTCCGCCAAGTGCAGGGGGCGCAAATAAGGGCGCAGATGCAAGGGGCGCAAATAAGGAATGCCATAAGTCATATGCAAGATGCGCCTATGGCGCTTTCGTACGCTTGGCAAGGTGATGCGTGA
- Protein Sequence
- MANTQLDFTKICRACLTDNAPMKDLFTVCSPDVYRYCTSVEVSEGDEMPKQVCEACLDLLNKFYYFKQVVIRSNAVLKQHCSVPVKVENQQVEEILMVALTGDSDEGSSQDNIQDQPMNEEANKTKPRKRRKYTRGAEKPKPKRPRMKCVKCEKSFQKYENLEAHMRSHFGKKPDIKCDHCEKTFLNFRSLNAHVRTHTGVRKYQCQTCGKHFAYLNVLKNHELIHSGVKKHACHICDMKFVQAYNLKMHLETHSAEKNYGCVQCGKKFSQPGNLKIHLIRHTGIKNIACTICDMKFYVKSDLYKHMRSHSENKPFGCSLCDKTFKSKSFQTVHMRTHTGERPYACDLCPKRFMARKDLRNHRMIHTGEKPHKCQLCNQAFIQKCALNRHMKGHGKSTADETLRQVQGAQIRAQMQGAQIRNAISHMQDAPMALSYAWQGDA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00674512;
- 90% Identity
- -
- 80% Identity
- -