Hpse021129.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_947369225.1
- Location
- OX376312.1:13016675-13028464[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 6.6 4.2e+02 2.1 0.4 2 23 270 291 270 291 0.74 2 13 0.0061 0.39 11.6 0.9 1 22 296 317 296 320 0.92 3 13 0.0032 0.2 12.5 1.8 2 23 440 462 439 462 0.94 4 13 0.00035 0.023 15.5 0.3 1 23 468 490 468 490 0.97 5 13 0.013 0.86 10.6 0.2 1 23 501 524 501 524 0.92 6 13 2.5e-07 1.6e-05 25.5 3.5 1 23 529 551 529 551 0.98 7 13 5.7e-06 0.00037 21.2 1.0 1 23 557 579 557 579 0.97 8 13 8.4e-05 0.0054 17.5 5.1 1 23 585 607 585 607 0.98 9 13 7.2e-08 4.6e-06 27.2 0.4 1 23 613 635 613 635 0.98 10 13 6.4e-06 0.00041 21.0 2.3 1 23 641 663 641 663 0.99 11 13 0.00041 0.026 15.4 0.1 1 22 669 690 669 690 0.95 12 13 0.00055 0.035 14.9 2.7 1 23 697 719 697 719 0.97 13 13 5.8e-06 0.00037 21.2 4.7 1 23 725 748 725 748 0.96
Sequence Information
- Coding Sequence
- ATGGAAGTTTTTCTCTATAATTCCACTGTTTGTAGATTATGTGGTGAAGAAAATGACAGTGGAACATTATTATATTCTTGTGAAGATAATAGTCAAAACCTAAGTGAAGTTATCAATAGCTATTTGCCGATCAAGGTATCGGACGATGGACAGTTGCCCCGAACCATCTGCCCAGGCTGCACAATCCAGCTGGAAGCTACAGTTGAATTCCTGAACCTTATCATCAATGGACAGAAAGTAATTCGTGAGCTGTACCAGAGGGAGAGAGAGTACAAAAAAACGATACTCAACAAAGAGTTACTAGTGGAGACTAGTAATCAAGATGTCATCACCGAGAAAATTGTCTATGAGATTAACACCAGCGATGGAGTGTACCAAGTGGAGCACCCGATCGCCCTCCAAGTGGCGGGGCTCGACCGCCCGAAGCGCAAGCGCGGACGGCCGCCCAAAAAGCCCAAGTCTCCAGAGGAGGTGGCACAGGAGGCCGCCGCCAGGGAGAAGGAAATAGCAGACAGGAAGGAGGGGAAACAGGACGAGGTCTCTGGGAAACGGAGGAGGAAGACTCCCACTAGGTTCCGGGAGGTTGTCCAGGGCAAAGAGCTAGATAGAATATTCAAAGAAGAAGGCGTCACAGACGGCGATGAGAGCGACGGGGAGGTGAAGCCGGAAGCTGACTTCAACACGCCGCCGCCGCCGCCCAAGGAGCCCGAGGTCATCGGCCACATGGAAACGTCTGGCGAGCTGGTCGTGGTGGTCAAGGGCAAGGGACGCGGCAGACCTAAAGGCCGCATGCGCCAAACTCGCGAAGAATGCGCGATATGTGGCATGGAGTTCTCATGCGTCGGCCGCTACATGTCGCATATCGCTCAGCACGGACCAGTCATGTACCAGTGTGGCCAGTGCTCGGCCACCTTCACCACCAGACTGACCTTCAAGGAGCACCAGCAGGAGAGTGGTCATACCGGGCAGAACGTTATACCCTGTGGCAAGACTGTGGAGCAAGTCGTTACGGACACGGAAGTAAACCCAGAGGAACCTACAAACAAACCCGACCAAGAAGGGCGGGACTCAGTCAACAAACTAGTCAGTGACATAGACATGGGCTCACTGCCCAAACTGCTGCCGGACCTGGGCAAAGCTGACGATGACCAGATCGGCACGGAGTTCCTCAAGAGTCTTGTCAATGAGAAGGTGGATGGTGTAGGCCAGGTTGATCCTAGTCAATGTGTTGATAAGAGTGATAAAGAAAACACTCGCCCTGAAAAGGCGGACGATCGCACGGCCGAGGCGACGGACCCCAAAGGGAAGGTGAAGCTCAAGTGTCCGCACTGCGACAAGCTATTCAGTAGTAAGCAGAGCAAGTCCATGCATATCAAGGCGGTGCACCAAGGGGAGCGTCCGTACGTGTGCAAGGAGTGCGGCTGCATGTTCGCGTACCCGCGCTCGCTCGCTCTACACGCGATCTCCCACCGGCGACACCGCGCGGGCGGCGCTCGCCGCTACGCCTGCGACCTGTGCGGGAAGGTCCTGAACCACCCGTCATCAGTGGTATACCACAAGCAGGCGGAGCACGCAGGACAGCGCTACGTGTGCAACAAGTGCGGCAAGTCCTTCAAGCACAAGCAGCTGCTGCAGCGGCACCAGCTCGTGCACTCGCAGCTGCGGCCCTACTCGTGCAAGACATGCAACGCATCATTCAAGACGAAGGCGAATCTTATCAACCACCAGCTGCTGCACACGGGCGTCAAGAAGTTCACGTGCGAGATCTGCAAGCACAAGTTCGCGCACAAGACCAGCCTCACGCTCCACATGAGATGGCACACCGGCTCAAAACCCTTCGTAtgcaaaatctgcggaaaaagcttcagtcagaaaggaaatctatcagaacacgagcgcatccacacgggagagaagccctaccagtgcactctctgtCCGCGACGCTTCACCACGTCGTCTCAGTACCGGCTGCACGCGCGGAGACACCAGCCGGAGAGACCGTACGCCTGCGCGCACTGCCCCAAACGATTCGTATCCCGCGGCTCCTGGGCGGCCCACCAACGCCGCGAAGCCGGGCTCCGCTCGCACCACTGCACAGTGTGCGCCCGCGCGTTCACGGAGCGCTGGGCGCTGTTGAAGCACATGCGGCGCCACACGGGCGAGCGCCCCTTCCGCTGCCCGCACTGCCCGCGCACCTTCGCGGACTGCTCCAACCTCAACAAACACAAGAAGCAAGTACACAAACAAATGAGCCTGCTAGTGACCAACGACAAGAAGCTAGACCCTCCGCGCAGCCCCGACGTGACGTCACAACCAGCGGACAGGCTGCAGATAGTGGAGGGGCCGCACTCGGAGCGCGACCTGGACGAGCGAGTCATATACGTCACGTACGACGTGGGCGGGGCGGAGCCCGCCTTCCACATACTGGACCCTGAACAGGCAGCGTCACTGGACGACAGTAAAGTCATAACAACGTGCGAACTCTACACGGACCCTTCACTGCTCGTTTCGCAGCCTGAACTGTTGGAGCACGAGCAGCTGGAGACGGAGGAGTTCGAGCAGCTCGACGACGGGATGGAGCTCGCCGAACCGCTCGACTTGTCCGACGACGAGCATATAGCGGTGACGGACGAGCAGGGCAACCCGCTGCACTTTACGATGCAGGACGGCACGCGGCTCGCCATCACTTCGGCCGACGGCAAGTCGTTGCAGGTAGTCACTCAAGATGGGCAAACGATTCCAGTGGAGATCAACGGATACGCCGAGGAAGAGGAGGTGGAGGAGCCACCACCCACGATAGTCCACCAGCTGGACCTGCACAAAGACGTGGACGCGGACGTCTCCTCGCCCGTCACGCACTTCTTCACCATCGTGTGA
- Protein Sequence
- MEVFLYNSTVCRLCGEENDSGTLLYSCEDNSQNLSEVINSYLPIKVSDDGQLPRTICPGCTIQLEATVEFLNLIINGQKVIRELYQREREYKKTILNKELLVETSNQDVITEKIVYEINTSDGVYQVEHPIALQVAGLDRPKRKRGRPPKKPKSPEEVAQEAAAREKEIADRKEGKQDEVSGKRRRKTPTRFREVVQGKELDRIFKEEGVTDGDESDGEVKPEADFNTPPPPPKEPEVIGHMETSGELVVVVKGKGRGRPKGRMRQTREECAICGMEFSCVGRYMSHIAQHGPVMYQCGQCSATFTTRLTFKEHQQESGHTGQNVIPCGKTVEQVVTDTEVNPEEPTNKPDQEGRDSVNKLVSDIDMGSLPKLLPDLGKADDDQIGTEFLKSLVNEKVDGVGQVDPSQCVDKSDKENTRPEKADDRTAEATDPKGKVKLKCPHCDKLFSSKQSKSMHIKAVHQGERPYVCKECGCMFAYPRSLALHAISHRRHRAGGARRYACDLCGKVLNHPSSVVYHKQAEHAGQRYVCNKCGKSFKHKQLLQRHQLVHSQLRPYSCKTCNASFKTKANLINHQLLHTGVKKFTCEICKHKFAHKTSLTLHMRWHTGSKPFVCKICGKSFSQKGNLSEHERIHTGEKPYQCTLCPRRFTTSSQYRLHARRHQPERPYACAHCPKRFVSRGSWAAHQRREAGLRSHHCTVCARAFTERWALLKHMRRHTGERPFRCPHCPRTFADCSNLNKHKKQVHKQMSLLVTNDKKLDPPRSPDVTSQPADRLQIVEGPHSERDLDERVIYVTYDVGGAEPAFHILDPEQAASLDDSKVITTCELYTDPSLLVSQPELLEHEQLETEEFEQLDDGMELAEPLDLSDDEHIAVTDEQGNPLHFTMQDGTRLAITSADGKSLQVVTQDGQTIPVEINGYAEEEEVEEPPPTIVHQLDLHKDVDADVSSPVTHFFTIV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -