Basic Information

Insect: Hofmannophila pseudospretella
Gene Symbol: ZFX
Assembly: GCA_947369225.1
Location: OX376330.1:12972949-12978793[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 5.7 3.6e+02 2.3 4.7 1 23 257 279 257 279 0.91

2 19 0.89 57 4.8 0.2 2 23 319 341 319 341 0.91

3 19 8.5e-06 0.00055 20.6 1.7 2 23 368 389 367 389 0.97

4 19 4.6e-06 0.0003 21.5 1.4 1 23 395 418 395 418 0.96

5 19 0.014 0.89 10.5 0.3 1 23 424 446 424 446 0.96

6 19 0.0044 0.28 12.1 4.6 1 23 452 474 452 474 0.96

7 19 0.06 3.8 8.5 3.2 1 23 633 655 633 655 0.95

8 19 0.0003 0.019 15.8 2.0 2 23 662 684 661 684 0.92

9 19 9.8e-06 0.00063 20.4 3.2 1 23 690 712 690 712 0.97

10 19 1.2e-06 7.9e-05 23.3 2.4 1 23 718 740 718 740 0.98

11 19 0.00045 0.029 15.2 1.1 1 23 746 768 746 768 0.98

12 19 0.00033 0.021 15.6 5.2 1 23 774 796 774 796 0.96

13 19 0.00031 0.02 15.7 2.8 1 23 802 825 802 825 0.97

14 19 1 67 4.6 0.4 3 23 899 918 898 918 0.89

15 19 5.8e-05 0.0037 18.0 0.2 1 23 924 947 924 947 0.96

16 19 2.1e-06 0.00014 22.5 7.3 1 23 953 975 953 975 0.98

17 19 0.00025 0.016 16.0 0.1 1 23 981 1003 981 1003 0.98

18 19 1.8e-05 0.0011 19.6 0.1 1 23 1009 1031 1009 1031 0.97

19 19 0.001 0.066 14.1 0.3 5 23 1040 1058 1038 1058 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	5.7	3.6e+02	2.3	4.7	1	23	257	279	257	279	0.91
2	19	0.89	57	4.8	0.2	2	23	319	341	319	341	0.91
3	19	8.5e-06	0.00055	20.6	1.7	2	23	368	389	367	389	0.97
4	19	4.6e-06	0.0003	21.5	1.4	1	23	395	418	395	418	0.96
5	19	0.014	0.89	10.5	0.3	1	23	424	446	424	446	0.96
6	19	0.0044	0.28	12.1	4.6	1	23	452	474	452	474	0.96
7	19	0.06	3.8	8.5	3.2	1	23	633	655	633	655	0.95
8	19	0.0003	0.019	15.8	2.0	2	23	662	684	661	684	0.92
9	19	9.8e-06	0.00063	20.4	3.2	1	23	690	712	690	712	0.97
10	19	1.2e-06	7.9e-05	23.3	2.4	1	23	718	740	718	740	0.98
11	19	0.00045	0.029	15.2	1.1	1	23	746	768	746	768	0.98
12	19	0.00033	0.021	15.6	5.2	1	23	774	796	774	796	0.96
13	19	0.00031	0.02	15.7	2.8	1	23	802	825	802	825	0.97
14	19	1	67	4.6	0.4	3	23	899	918	898	918	0.89
15	19	5.8e-05	0.0037	18.0	0.2	1	23	924	947	924	947	0.96
16	19	2.1e-06	0.00014	22.5	7.3	1	23	953	975	953	975	0.98
17	19	0.00025	0.016	16.0	0.1	1	23	981	1003	981	1003	0.98
18	19	1.8e-05	0.0011	19.6	0.1	1	23	1009	1031	1009	1031	0.97
19	19	0.001	0.066	14.1	0.3	5	23	1040	1058	1038	1058	0.97

Sequence Information

Coding Sequence: ATGAATAACGAAACAGAACAAATATTTCTGATAAACTCCTCGGAAACCCAGCTGTCCAGCGACTCTCAGAAGATAATAGAAGTGCCTTCAGTAGCACAGGTTAACCTCGAGAATGTGGAGGACTTCTCGACCGTGTGCCGAACGTGCGCCACCATCACGGAGTACGTGATCCCCATCTTCGAGGGTGAGGGCCTGCAGAACAGCCTCGCCGACAAGATCCACAAACACTTGCCTATACAGGTATGCCCGGGGGACGCATTGCCGCGCGCAGTTTGCTACCAGTGTGCACACACGCTGCTGGCGTGGCACGAGCTGGTGGCGTGCTGCGAGCAGGCCGACGCCGCGCTGCGCACCCGCCTAGCGCAGCTAGATGTCGCCCGCGCCTGCGCTACGGGACAGGAACAGCAACCAACAACAAGTGAAGAAGACCAAAGTTTAAAACATAAGGAACAGAAAGAGTCACAAACCAGATTTCACACAATCGTAAAAAATGTGCTAAACGACTACTTTCGCATGCTAGATATGGATGGAGAAAATAACTTGGAATTTGTTTGCCAAAAATGTTCCGAAAATCCAGTCTCGAAATCTGTGGAGAGCCTGGTGGAACATTTAAACTCTCTACATTCCTCTGAATTGAGCAGTAAAGTGAAGATAAAACAATTTATAAAACATTTCGTTACTTTTGAGGAGCCATTGATGCTAGAAGATTCAGACAGAGATGGAGATTCAGTCAGGGAAACGCCTGAATCACCGGTAGCATTGAAGGCTTATTGTTGCCCGTACTGCAGAAGCATGTTCTCTTCAGCGACTCGTCTAATCTGCCATCTCAGCCAGCATATGGACATGTGCATCGAACAAGGAGTGATCTGCTGTGAAACCTACTACGACAATAAGAACTTTTTCGCGAAACACTTGCAAGAAAAACATGTGGATCGAGATATCACTACCCCGAATACGTGTCGAAGCTGTGGATACGAGGCCGATAGCAGCGAAGATCTTCAGTCTCACGTAACCAATACTCACGAAGGTAGCACAAGTAAAGAAGTCGACACAAAGAACATTAAAAAACGCAGCACAAAAGATCAAAAATACATCTCAGTGTCATGTCCAGAGTGCAATAAAACTTATTCCAATAAATACCACATGCTCATCCATTTGAGAAGCCATTCGGAGACGACACGATTCTTCTGCACTGAATGTGAAAAATCTTACTCAAACCAGGGAAACTTGAACAAGCACAAGAAAATAGTACACGAGGGTGTATTAAAGTTTACTTGCTCGTTCTGTGGGGAGGCGTTCCCGTCTCGCCGAGCACGAGACAACCACGCACGACTGCACACAGGAGAAAAACCGTTCACCTGCCAGTATTGCAATAAATCCTACCGCTCCAAACAGACGTTAACGTGCCACATTGACATACATTTAGGCGTAAGGAAGTGCAAGTCCTGCCGAAATAACTTCGAAACTCAATTGGCGACGCGCGAGACAAGCGTACACGACATCGCCGATAACGTGAACAAAGATGTAAATTTCGAAATCGCATTAGAACCCGACGATGACAATTTTGATGGCGCCAGTTCACCTCAGTCTGAAGACGATGATGAGCCTCTTTCTACAATTGCAAGCAAGAAATCGAACAATCTTTACAGCGACTTCTACACGGCATTGATCAATTTCAGAAATCATTTTGTAACGGAACATAAAACCAGACACAGTTACCCCGATTTTACCGACTCCAGCGACGGCGAGGTCCCGAGGGACAACGGCGATGTCGACGACATAAACGTGGACAGCTTCGACGACCTCACACACAGCAACATGCGGAAAGACAGAATGGACGAGGAGACACGACTGGAGCTCAGTCAAGTGCAGATGAAAATAAACGGAAAAGTTTACTACTCGTGTAAGATATGCGGGAAGAACTTGAGTTCTTCGCACACGTACGTGTTCCACAAGCGCATCCACACGGGGGAGCGGCCCTGCGTGTGCCACATCTGCGGGAAACAGTTCCGCGCCCCGAACGGGCTCCAGAGGCATCTGACGGAGACCCACGAGAAGGTCCGCCGCCACTCCTGCCGGTTCTGTCCGAAGAACTTCGCCAATTCCCAGAACTTGAAACAGCACATGCGGATTCACACCGGAGAGCGGCCGTTCGTGTGTTCTCAGTGCGGGAAACGCTTCACCCAGAGTGGATCTCTGCACGTTCACTTGAAAACGCACAGCGAGCAGTTTCCTTACCACTGTGCGGAGTGCGGGGCTAAGTTCCGATTGAGGTCGGGGCTGGCGAGGCATAGATTAAAACACACGGGGGAAAGACCGCACGTATGCGTCCATTGTGGCAAGGGATTCCGGCAGAAGCACGAATTGAACAGCCATAGTCTATCCCACAGCGACACCAAGCCGTTCAGCTGCGCGGTGTGCGGCGCAGCCTTCAGGCAGCGCAGAGCGTTGCGGCACCACCACAAACGTCTGCACGAGACCGAGCCGCCGGCGGACGTGGCTGCCTCCCTCGTGCCGCGCGGCTCCGATATGTTAATCTACACCAATATCGGACAGTATCAACAAACATTGACTAACACACAGCTGACGAGAGAAGTCGAGAAAACTACAGAAGATGACCAAACTCAACCGAAAGAAAACCTTGAAAGACCCGCGAACGTTACGATGGGAGCAGACGGAAAAAAGTACGTCGCGTGCGAAATTTGTAAGAAAAACATAGCGACCAGCTCGTGGCGACGCCATTTACGATCCCATCGTGCGGAAAAATGTTACAGCTGCCACGCGTGTGGACTCGGCTTCAACGACAGTGGGAACCTAGCGCGACACACCAGAGCCATACACTCCAAGCAGCGCCCCCACACGTGCGAAATATGTCATAAAAGCTTCTCCAGATACAGCCATCTACAGGACCACATCAGATCGCACTCCGAAAACAGAGAGTTCGTCTGCGATCTCTGCGGGAAGGCGTCCAAATCCGGCGCAGCCTTGCGAATGCACAGACGGACTCACGAGAGCGAATGTCACTTTACGTGCGTGGAGTGCGGCGCCGGGTTCAAGCGGCGGTCAGAGCTGCGCGCGCACGTGACCGTGCACACGGGCGAGCGCGCGCACGCGTGTGGCTGCGGTCGCGCCTTCCGCCTGCGCAGCCAGCTCACCGCCCACGCCAAGACACACGATACTGACGAATAA
Protein Sequence: MNNETEQIFLINSSETQLSSDSQKIIEVPSVAQVNLENVEDFSTVCRTCATITEYVIPIFEGEGLQNSLADKIHKHLPIQVCPGDALPRAVCYQCAHTLLAWHELVACCEQADAALRTRLAQLDVARACATGQEQQPTTSEEDQSLKHKEQKESQTRFHTIVKNVLNDYFRMLDMDGENNLEFVCQKCSENPVSKSVESLVEHLNSLHSSELSSKVKIKQFIKHFVTFEEPLMLEDSDRDGDSVRETPESPVALKAYCCPYCRSMFSSATRLICHLSQHMDMCIEQGVICCETYYDNKNFFAKHLQEKHVDRDITTPNTCRSCGYEADSSEDLQSHVTNTHEGSTSKEVDTKNIKKRSTKDQKYISVSCPECNKTYSNKYHMLIHLRSHSETTRFFCTECEKSYSNQGNLNKHKKIVHEGVLKFTCSFCGEAFPSRRARDNHARLHTGEKPFTCQYCNKSYRSKQTLTCHIDIHLGVRKCKSCRNNFETQLATRETSVHDIADNVNKDVNFEIALEPDDDNFDGASSPQSEDDDEPLSTIASKKSNNLYSDFYTALINFRNHFVTEHKTRHSYPDFTDSSDGEVPRDNGDVDDINVDSFDDLTHSNMRKDRMDEETRLELSQVQMKINGKVYYSCKICGKNLSSSHTYVFHKRIHTGERPCVCHICGKQFRAPNGLQRHLTETHEKVRRHSCRFCPKNFANSQNLKQHMRIHTGERPFVCSQCGKRFTQSGSLHVHLKTHSEQFPYHCAECGAKFRLRSGLARHRLKHTGERPHVCVHCGKGFRQKHELNSHSLSHSDTKPFSCAVCGAAFRQRRALRHHHKRLHETEPPADVAASLVPRGSDMLIYTNIGQYQQTLTNTQLTREVEKTTEDDQTQPKENLERPANVTMGADGKKYVACEICKKNIATSSWRRHLRSHRAEKCYSCHACGLGFNDSGNLARHTRAIHSKQRPHTCEICHKSFSRYSHLQDHIRSHSENREFVCDLCGKASKSGAALRMHRRTHESECHFTCVECGAGFKRRSELRAHVTVHTGERAHACGCGRAFRLRSQLTAHAKTHDTDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -