Basic Information

Insect: Hofmannophila pseudospretella
Gene Symbol: ZFX
Assembly: GCA_947369225.1
Location: OX376337.1:7246711-7258614[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 35 6.5e-06 0.00041 21.0 2.0 1 23 120 142 120 142 0.98

2 35 7.9e-05 0.005 17.6 2.7 1 23 176 198 176 198 0.98

3 35 0.57 37 5.4 1.0 2 13 228 239 227 240 0.91

4 35 0.006 0.39 11.7 1.2 5 21 243 259 241 260 0.91

5 35 8.5e-06 0.00055 20.6 1.5 1 23 275 297 275 297 0.98

6 35 0.0065 0.42 11.6 0.7 1 23 303 326 303 326 0.94

7 35 0.00052 0.034 15.0 1.8 2 21 375 394 374 395 0.93

8 35 0.15 9.7 7.3 1.9 1 23 468 490 468 490 0.95

9 35 0.0066 0.42 11.5 0.5 1 23 496 518 496 518 0.98

10 35 0.00059 0.038 14.8 5.0 1 23 524 546 524 546 0.98

11 35 0.0043 0.28 12.1 1.2 3 23 552 572 551 572 0.97

12 35 0.0017 0.11 13.4 1.5 1 23 577 599 577 599 0.97

13 35 2.1e-05 0.0014 19.4 0.8 1 23 605 627 605 627 0.98

14 35 3.2e-05 0.0021 18.8 1.3 1 23 633 655 633 655 0.99

15 35 9.2e-05 0.0059 17.4 1.9 1 23 678 700 678 700 0.98

16 35 4.6e-05 0.0029 18.3 0.8 1 23 723 745 723 745 0.98

17 35 0.00026 0.016 16.0 1.7 2 23 752 774 751 774 0.96

18 35 6e-06 0.00039 21.1 2.7 1 23 851 873 851 873 0.95

19 35 2e-05 0.0013 19.4 0.9 1 23 879 902 879 902 0.97

20 35 0.0038 0.24 12.3 6.3 1 21 962 982 962 983 0.94

21 35 0.0002 0.013 16.3 4.5 1 23 1090 1112 1090 1112 0.98

22 35 0.51 33 5.6 2.5 1 17 1144 1160 1144 1160 0.89

23 35 0.089 5.7 8.0 0.0 5 19 1278 1292 1277 1294 0.93

24 35 1e-05 0.00067 20.3 1.6 1 23 1313 1335 1313 1335 0.98

25 35 0.0018 0.12 13.3 0.7 1 23 1341 1364 1341 1364 0.94

26 35 0.045 2.9 8.9 0.7 1 21 1557 1577 1557 1578 0.95

27 35 0.00022 0.014 16.2 2.1 1 23 1656 1678 1656 1678 0.98

28 35 0.013 0.85 10.6 1.0 1 23 1714 1736 1709 1736 0.97

29 35 0.0082 0.53 11.2 5.6 2 23 1743 1764 1742 1764 0.96

30 35 0.00011 0.0069 17.2 4.5 1 23 1770 1792 1770 1792 0.98

31 35 4.3e-05 0.0028 18.4 0.6 1 23 1798 1820 1798 1820 0.97

32 35 0.00046 0.029 15.2 0.5 1 23 1826 1848 1826 1848 0.98

33 35 0.00015 0.0093 16.8 0.3 3 23 1863 1883 1861 1883 0.97

34 35 7e-06 0.00045 20.9 0.9 1 23 1889 1911 1889 1911 0.98

35 35 1.5 97 4.1 6.1 1 22 1917 1938 1917 1938 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	35	6.5e-06	0.00041	21.0	2.0	1	23	120	142	120	142	0.98
2	35	7.9e-05	0.005	17.6	2.7	1	23	176	198	176	198	0.98
3	35	0.57	37	5.4	1.0	2	13	228	239	227	240	0.91
4	35	0.006	0.39	11.7	1.2	5	21	243	259	241	260	0.91
5	35	8.5e-06	0.00055	20.6	1.5	1	23	275	297	275	297	0.98
6	35	0.0065	0.42	11.6	0.7	1	23	303	326	303	326	0.94
7	35	0.00052	0.034	15.0	1.8	2	21	375	394	374	395	0.93
8	35	0.15	9.7	7.3	1.9	1	23	468	490	468	490	0.95
9	35	0.0066	0.42	11.5	0.5	1	23	496	518	496	518	0.98
10	35	0.00059	0.038	14.8	5.0	1	23	524	546	524	546	0.98
11	35	0.0043	0.28	12.1	1.2	3	23	552	572	551	572	0.97
12	35	0.0017	0.11	13.4	1.5	1	23	577	599	577	599	0.97
13	35	2.1e-05	0.0014	19.4	0.8	1	23	605	627	605	627	0.98
14	35	3.2e-05	0.0021	18.8	1.3	1	23	633	655	633	655	0.99
15	35	9.2e-05	0.0059	17.4	1.9	1	23	678	700	678	700	0.98
16	35	4.6e-05	0.0029	18.3	0.8	1	23	723	745	723	745	0.98
17	35	0.00026	0.016	16.0	1.7	2	23	752	774	751	774	0.96
18	35	6e-06	0.00039	21.1	2.7	1	23	851	873	851	873	0.95
19	35	2e-05	0.0013	19.4	0.9	1	23	879	902	879	902	0.97
20	35	0.0038	0.24	12.3	6.3	1	21	962	982	962	983	0.94
21	35	0.0002	0.013	16.3	4.5	1	23	1090	1112	1090	1112	0.98
22	35	0.51	33	5.6	2.5	1	17	1144	1160	1144	1160	0.89
23	35	0.089	5.7	8.0	0.0	5	19	1278	1292	1277	1294	0.93
24	35	1e-05	0.00067	20.3	1.6	1	23	1313	1335	1313	1335	0.98
25	35	0.0018	0.12	13.3	0.7	1	23	1341	1364	1341	1364	0.94
26	35	0.045	2.9	8.9	0.7	1	21	1557	1577	1557	1578	0.95
27	35	0.00022	0.014	16.2	2.1	1	23	1656	1678	1656	1678	0.98
28	35	0.013	0.85	10.6	1.0	1	23	1714	1736	1709	1736	0.97
29	35	0.0082	0.53	11.2	5.6	2	23	1743	1764	1742	1764	0.96
30	35	0.00011	0.0069	17.2	4.5	1	23	1770	1792	1770	1792	0.98
31	35	4.3e-05	0.0028	18.4	0.6	1	23	1798	1820	1798	1820	0.97
32	35	0.00046	0.029	15.2	0.5	1	23	1826	1848	1826	1848	0.98
33	35	0.00015	0.0093	16.8	0.3	3	23	1863	1883	1861	1883	0.97
34	35	7e-06	0.00045	20.9	0.9	1	23	1889	1911	1889	1911	0.98
35	35	1.5	97	4.1	6.1	1	22	1917	1938	1917	1938	0.95

Sequence Information

Coding Sequence: ATGCCTAGTGATGTTTCCAATACAGGATTCATCAAGGAAGAACCCAATTGTGAAGAAAATGAAGTAATTATAAAACTAGAAAATTGCTATGAGGAACAACATAATAAGCGACAACCTTCAGAAAAGGGGGATCGAAATCAGATTTCGTATTCTAGCCATGAGGTGAAAGATGAGTTAGATAATGAACCCAATTTAATGCAGCAGTCTATGCCATTTACTTCAGATATAGATAGTACTACAGAAGTGAAATCATTGCCATCCAATGAAGAATATTCATCAATCACTCGGCTACCAACACTAAAATACCACCAGGACACTAATAGAAGCGATAAACTTGTGCAGACTAAAGAACAATTATTCCCTTGTGATATTTGTAAACAAAGTTTTAACAGAATATCTCATTTAAAACGTCATCAGCTTGTACACAGCAAAGATACACCGTTTACATATGATAAATGTAACGGCAGTTTTAACACCAAACATAATTTAACATGTTACCAAGCTACACGAAACAACAAAAGCTTATTCTCATGTGATGTCTGCAAGCAAAGGTTTAACAGAAAACCTCATTTGCTACGGCACCAATTAGTGCATACAAAGGAAAAAGCATTCTGCAATGTTACCGGAATAAAAATTGATCTGGAACGACATCAACAAGTCAATAATGAAGAAAGGGCGCAGACCTGCGGTGATTGTGATAAAATATTTTCAACAAAATTTCCTTGTAAATGTGGAAAGAAGTTCTCCGATAAAGAGTCTTTGAAACAACACAAATGTGTTGATAAGAAATCTAAAAAGGAACAGTTTAATTTAGAAAAAATATTTTCATGTGACATTTGCGATAAAGGATTTAATACCAGTTACCGTTTAGAACGTCACAAACGTATGCACAGAGTCAGAAAACCATTTCTATGTGAAATTTGCAAAAAATCCTTTGCTAACGTGTCTATTCTGACGAATCACAAAAAACGTGTTCACAAAAAGCCCAGTAATGTTACTTCTAAAGAACAATATGTGCAGGAACCGATGCTTGTATCACACGAGTATGATAACAGTGAGGAAAACCCACTGAAATGTGATATTTCTGAAGAACAGTTGTCTCACATAAAAGAAGAACAATTGGAATGCCATGTTTGTAATGAAAAATTCAATACAAAATCAGAATTATTATCACACCAATGTGTTAATAATGAAGAAGAGATTATCTGTAATGATGAAAAAGAATTCCAGAATTACAATGAAACATTTTCTTCTAAAGAAAAGACATTGTCAATTAAAGAAGAACCAAAAACTCCTGAACGTGTTCGAGTTCCTAAAACTGAAGAAAGTCATTCTAAATCTAATAGTGCTTGCACAAATGAACAAAAGTTTACAGAATCGTTCAGTGACGGGAAAACAGTGTTCTCATGTATTATTTGTGCGAAGCAATATTCACGTAAACAATCAGTGATCGTTCACCATCGCACCCACACTGATAACAAACCTTATTCGTGCAATGTGTGTAGTAAACAATTTATAGTGAAAGCATTTTATAAGGAACATCTGATTGTTCATACGGATGAAAAGCCATTCGAATGTAATTTATGTCACCAGCAGTTCAAACACAAATCTGCTCTAGTGCTACACCTTAAACGCCACAATCGTCAAAACATATGTGATATTTGCAAGATGAAGTTTAATACCAGATTAGAGTTGAGGCAGCACAGACTGAGTCATATAGAAAGTCTGTTTCCATGCGCTACTTGTCCTAAAAAATTCATTTCCCAGACTTGTTTAGACAGACATCGTCTGATTCATGCTGGAAATAGGCCGTTCCCTTGTAGTTTTTGCCCAAAAGAGTTTATTGTTAAATTTGATCTGCTGCGCCATATGCGGAAGCATACTGGAGAAAAACCATACACCTGTGACATTTGTAAAAAGGAATTCGCTAATCGATCTTGTGTGATAGCCCATCTTCGCATGCACAGTTCAAGAAATGAATCTAATACTCAAAAAGGAGCTAAAATGAATAAGGATAGAAAAAGATCTGGTTATGTTTGTGATATCTGCAATCTGAGATTCACAAGTAAAGAGTCATTTAATTCCCACAAACGAAACCATGCAGGCGTCAAACCAGTTTTATGCGATGTCTCTGACCAAAGATACAATTGGAAATCTGACAAACCTTTCTCGTGTGATGTCTGTGAGAAAGGATTCCCTTATAAATCGAAATTGGATCGTCATAGGCGCGTCCATACCGGAGAAAAACCGATTTCTTGTGACGTTTGCCATAGTTCTTTCACTGACACGTCCAATCTCAGATATCATATTAAAAAAGTTCACCTTAAAATTAAACCACTGTATATTAAAGGAGAATTCTTTTGTAATCTATGTAAGAAACATTTGACTGACAAAGAGTTATCGACACACGATTGTGTTCGAAATGAAGAAGAAACTTCGAACGATGATTCAGATAAAAAGATTGGAGGAAACATAACGGATTACCAAATCAGTTTACTGCGCGGTCTACTTGTCACTCGGCGAAGTAAAAAGAAGGGTGATAAACAACCGTTCCTCTGTTATACATGTGGAAAAAGATTTGTCAATAATTATCGACTCACGCGCCACATGCGCACGCATACTAGAGAAAAGCCATATTCATGCGATGTATGCTCAAAATCTTTCTCTGACAGATCTGCTATGGTGAAACACAGGAAACGGGTTCATAAAATTAAAACAACTCCGGGTAGCCACAAAAAAATTTCACAAAATCTTAATCCTGTTGAACAATTAACACAAAACCCTACATTATTGATCAAGAATGATTGTGATGAACAGAAACCTTTACTGCCTGATTCAAACAATACTCCTGAAGAGTCGCAATCCGTGTACATTAAACTAGAATTCTCTTGCAATGTTTGTAAAAAGTATTTCACTCACAAATCACAGTTAATGTCGCACCACTGTGTTAACGATAAAAAAACTTCCACAAGTAAAGAAGAAATATTTAATGAAGAAGACACATTCTCAAATAAAGAAGAGTTATTTACAAATGAAAAAGACATAGTCTCAAAAGAAGAAGAGACATTTACAAATGAGGAAGACACATTCTCAGATCAGTTCCCACATTCAGCAGAACCAACACACCAAGACGTTGGTGAGGAATTCTACCCGATTATTAAAACTGAAGAAACTGTGCCTCGTTCTATAGCTCGCAACGATGAAGAAAAGCGAAGAATGACTCCTAGACGCCGTGAACATCTGCGTGTACACAGCGGAGAAAAGCCATTCATGTGTCATATTTGCGACTACAAGTGTGCACAGACTTCAGCACTGAAATCTCACCTGCGTACCCATGTCAAACAAGGTGTTAAAAATGAGGAAACGAGTATTGGAAACAAGGAACCGAACAGGACTAACATAGCTCCAGCTATAACACCAAGAAGCGCGTTCGTTTGCGATGTCTGCGGCAAACAGTTTCAAAAGAAATATTGTCTACAGCCTATCCCTATCCATTCGTCGGATTCCCACCTTTCCCATGGAATACTGATGGGACAAATGGGAGATCACTTGAGACATAGCGTCATGTCTAACCACACCGATCTCAGTGCCACTGTGAAGGAAGAACCCACTGTTATAGAGCAGTTGGCTCATGAACTGACTGAGGAGATAGAATCTGGTTCCCTCAGCAACTATGAAGAACCAGTAATCAAACAAGATCATTTAGAAGAAGACAATGTGAAGAAACAGGACTTGTATACCGACGGTGTAGTGAAGACTGAGTTGGTAATTGGCCTTGGGGAGATGCAGCGGCCCGTTACACTAATATCTGAAATAGGGAGCAGTAGCAATGATTGTGGACCAATATTCTCCACGAAGGCTTCTTTGAGACGACATGAGATTGATAAAAAACTACTTGCTTCCAAAAAGAAACTGGCAGATTTAGAAGAAAAACCTTTTACATGTGACGTTTGCGACAAAGGATTTAATACCAGTTACCGTTTAGAACGTCACAAACGTATGCACAGAGTCAGAAAACCATTTCTATGTGAAATTTGCAACAAGTCTTTTGCTAAAATGTCCGTTCTAATAAATCACAAGAAACGTCTTCATAAAAATATCAGCGGTATCTCTGATCAACGGTTCATACGGAAGTCTACACTGGTGTCACAAGAATTTGATAGCAGTGAAGAAAACCCACTGAAATGTGATGTTTCTGAAGAACAGTTGTTACACATAAAAGAAGAACATGTTAAAACAGAGCCATTGGAATTCAGAACGATTGAGAAGTCAGAGCTGCTATCTCATCAGTATGTTCATAATGAGAAAGGGACACGCTATGATGAAGACCAATTATCTAATGATGAAGACACATTGTCAACCAAAGAAGAGACGTCGATTAAAGAAGAATCTAAACCTCACATTAAAACTGAAGAAAAAATATCAGTCATTAAGACCAGATCCAATCGTGTTCACACTAATGAACAAAACCCGAAAGAACAATTCACACGTAATTCAACGAAGGATGAAACGTATGATGAACAAAAAATAAATGCACAGAGTGTTATTGATCCCCAAATTACGCAAGAGAGGACACTAAAATCTCCCCAAAAAGATGACAATGAAGAAAAACCACCATTGCTTAACATTCCTGAAGAACAATCACATTCCGTATACATCAAACTGGAATTTACTTGTGACGTCTGTGAAATGGATTTCACTGACCGTTCTGTTTTTATGTCACATCAGTGTGGTCGCAGTGAAGAAACTTTTTCAAATAAAGAAGAACTATTGTCAAATGAAGAAGACGCAGAGTCTGATATTGATCAATTTGCACAGGATTCAGCAGAACCACCAGATGTTGACAGTGAGGAATACTACTTAATTATTAAAGAGGAAGAAAGGACAGTATCTCATTCTTCTGTACGTAACCATGAAGAAAAACCAAAACCTAGGGCTACTAAACGTGTTACCAGTGATAAACTATTCGAATGTGATAATTGTGGACGGCATTACACAAATAGAAAATCTATTGTAAGGCACTTACGTATTCATAATAATAAAAAGAAACCTTATAAACAAAACGTGGACAAAACCTTACAAAGGAAACGTAATAAAGCCGTTGGAAAACAAGGTACCAGTGCAAAATGTGACAAATCGTTCATATGTGATATATGTGGACAACAATTAGTGCGTATAAAATCGATGAATAAACATATGCAAGCTCATAGTGACAATAAATCCTTGCCGTGTGAACATTGCAATAAGGAATTCTTTTCAAAAAACAAATTAGATCACCATAGACGTAGTCACATCGGCACCATACAATTCTCATGCGAGGAATGCAAGAAGACTTTTAATCACAGATCATCATACGTTTACCACCAAAGAGTTCACAGTGGAGAAAAACCTTATTCCTGCGATGTATGCGGTAAAACCTTCGCATTCAGAGGGAATTGGAAAACACACCGAACTGTTCATAACGGAGAAAAACCATTCTCTTGTGCCATTTGTGGATTGAAGTTCAGACTGAAACCGATGTTAAAAATTCATTTAAAAAAGCATATGGAAAAGGATATGCCTTCGAAGGAAAAATCTCATGTTATTTGCAATGTATGCGGGAAGAAACTCGCGAGGAAAGATGTCTTGCAAAAACATATGTTCACACATTCTGATAAGAAACCCTTTCCGTGTAATCTTTGTGAGAAACAGTACACTGTTAGTGATTCTTTGAGGCGGCACATGCGATCTCATACGGGGGAGAAGCCGTATTCGTGCGATTGTTGTAACAAGCGGTTCAGACACAGGACTGGATTCGTTTACCATCAGCGGAAAGGCTGTAAAAACAAATAA
Protein Sequence: MPSDVSNTGFIKEEPNCEENEVIIKLENCYEEQHNKRQPSEKGDRNQISYSSHEVKDELDNEPNLMQQSMPFTSDIDSTTEVKSLPSNEEYSSITRLPTLKYHQDTNRSDKLVQTKEQLFPCDICKQSFNRISHLKRHQLVHSKDTPFTYDKCNGSFNTKHNLTCYQATRNNKSLFSCDVCKQRFNRKPHLLRHQLVHTKEKAFCNVTGIKIDLERHQQVNNEERAQTCGDCDKIFSTKFPCKCGKKFSDKESLKQHKCVDKKSKKEQFNLEKIFSCDICDKGFNTSYRLERHKRMHRVRKPFLCEICKKSFANVSILTNHKKRVHKKPSNVTSKEQYVQEPMLVSHEYDNSEENPLKCDISEEQLSHIKEEQLECHVCNEKFNTKSELLSHQCVNNEEEIICNDEKEFQNYNETFSSKEKTLSIKEEPKTPERVRVPKTEESHSKSNSACTNEQKFTESFSDGKTVFSCIICAKQYSRKQSVIVHHRTHTDNKPYSCNVCSKQFIVKAFYKEHLIVHTDEKPFECNLCHQQFKHKSALVLHLKRHNRQNICDICKMKFNTRLELRQHRLSHIESLFPCATCPKKFISQTCLDRHRLIHAGNRPFPCSFCPKEFIVKFDLLRHMRKHTGEKPYTCDICKKEFANRSCVIAHLRMHSSRNESNTQKGAKMNKDRKRSGYVCDICNLRFTSKESFNSHKRNHAGVKPVLCDVSDQRYNWKSDKPFSCDVCEKGFPYKSKLDRHRRVHTGEKPISCDVCHSSFTDTSNLRYHIKKVHLKIKPLYIKGEFFCNLCKKHLTDKELSTHDCVRNEEETSNDDSDKKIGGNITDYQISLLRGLLVTRRSKKKGDKQPFLCYTCGKRFVNNYRLTRHMRTHTREKPYSCDVCSKSFSDRSAMVKHRKRVHKIKTTPGSHKKISQNLNPVEQLTQNPTLLIKNDCDEQKPLLPDSNNTPEESQSVYIKLEFSCNVCKKYFTHKSQLMSHHCVNDKKTSTSKEEIFNEEDTFSNKEELFTNEKDIVSKEEETFTNEEDTFSDQFPHSAEPTHQDVGEEFYPIIKTEETVPRSIARNDEEKRRMTPRRREHLRVHSGEKPFMCHICDYKCAQTSALKSHLRTHVKQGVKNEETSIGNKEPNRTNIAPAITPRSAFVCDVCGKQFQKKYCLQPIPIHSSDSHLSHGILMGQMGDHLRHSVMSNHTDLSATVKEEPTVIEQLAHELTEEIESGSLSNYEEPVIKQDHLEEDNVKKQDLYTDGVVKTELVIGLGEMQRPVTLISEIGSSSNDCGPIFSTKASLRRHEIDKKLLASKKKLADLEEKPFTCDVCDKGFNTSYRLERHKRMHRVRKPFLCEICNKSFAKMSVLINHKKRLHKNISGISDQRFIRKSTLVSQEFDSSEENPLKCDVSEEQLLHIKEEHVKTEPLEFRTIEKSELLSHQYVHNEKGTRYDEDQLSNDEDTLSTKEETSIKEESKPHIKTEEKISVIKTRSNRVHTNEQNPKEQFTRNSTKDETYDEQKINAQSVIDPQITQERTLKSPQKDDNEEKPPLLNIPEEQSHSVYIKLEFTCDVCEMDFTDRSVFMSHQCGRSEETFSNKEELLSNEEDAESDIDQFAQDSAEPPDVDSEEYYLIIKEEERTVSHSSVRNHEEKPKPRATKRVTSDKLFECDNCGRHYTNRKSIVRHLRIHNNKKKPYKQNVDKTLQRKRNKAVGKQGTSAKCDKSFICDICGQQLVRIKSMNKHMQAHSDNKSLPCEHCNKEFFSKNKLDHHRRSHIGTIQFSCEECKKTFNHRSSYVYHQRVHSGEKPYSCDVCGKTFAFRGNWKTHRTVHNGEKPFSCAICGLKFRLKPMLKIHLKKHMEKDMPSKEKSHVICNVCGKKLARKDVLQKHMFTHSDKKPFPCNLCEKQYTVSDSLRRHMRSHTGEKPYSCDCCNKRFRHRTGFVYHQRKGCKNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -